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21081
Transurethral Water Vapor Ablation: Potential for a Novel Prostate Cancer Management Strategy
Published 2025-02-01“…It is possible to successfully retreat residual disease or new lesions identified on surveillance with only transient mild to moderate adverse events and acceptable oncologic outcomes offering a new management strategy for localized prostate cancer.Plain Language Summary: Treatment decisions for men with localized prostate cancer (PCa) are determined with consideration of multiple factors including, disease risk, co-morbidities, estimated life-expectancy and each patient’s preferences. Currently, many men with low-risk disease are offered active surveillance, during which the prostate cancer is closely monitored for any changes, whereas men with intermediate or high-risk localized cancers are more often considered for surgical removal of the prostate or treatment with radiation. …”
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21082
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21083
Investigating mental health disparities in rural sexual and gender minority adults: protocol for the rural exploration and approaches to LGBTQ + Mental Health (REALM) prospective c...
Published 2025-02-01“…Abstract Background Sexual and gender minority (SGM) persons experience substantial mental health disparities throughout the life course, including increased vulnerability to depression and suicide. …”
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21084
The effect of irrigation practice and water consumption using aqua-crop
Published 2024-10-01“…The study also looks into how to achieve sustainable water management in the agricultural sector.METHODS: Aqua-crop, a computerized model, was utilized mimic real-life crop harvests. The aqua crop model was used to simulate crop yield in response to water availability. …”
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21085
Low & Anaplastic Grade Glioma Umbrella Study of MOlecular Guided TherapieS (LUMOS-2): study protocol for a phase 2, prospective, multicentre, open-label, multiarm, biomarker-direct...
Published 2025-02-01“…Secondary objectives include assessment of overall survival, response rate, safety and quality of life measures. Two additional therapeutic arms are currently in development.Ethics and dissemination Central ethics approval was obtained from the Sydney Local Health District Ethics Review Committee, Royal Prince Alfred Hospital Zone, Sydney, Australia (Approval: 2022/ETH02230). …”
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21086
Efficacy of the internet-based intervention “Cultivating our resilience” (CORE) for improving resilience and coping strategies in university students: A randomized controlled trial...
Published 2025-03-01“…A total of 493 students with low levels of resilience participated in the study.Participants in the intervention group gained access to an internet-based program aiming to enhance resilience by learning to cope with stressors in daily life, promote self-empowerment, and improve well-being. …”
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21089
Balneotherapy for the treatment of post-COVID syndrome: a randomized controlled trial
Published 2025-02-01“…The following scales/questionnaires were employed: Post-COVID-19 functional status scale, mMRC dyspnea Scale, SF-36, Pittsburgh Sleep Quality Index (PSQI), Hospital Anxiety and Depression Scale (HADS), Memory failures in everyday life following severe head injury, and Visual Analogic Scale (VAS). …”
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21090
Reims antique, acquis et perspectives
Published 2022-11-01“…City officials undertook the construction of attributes worthy of a Roman provincial capital: a powerful city wall, remarkable monumental decorations, large public spaces devoted to civic and economic life, circulation routes, water supply and drainage networks, etc. …”
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21092
Observational study on the current status of thalassaemia in Malaysia: a report from the Malaysian Thalassaemia Registry
Published 2020-06-01“…However, cardiac complications are still the main cause of death in patients with thalassaemia.Conclusion Data gathered into the registry can be used to understand the progression of the disorder, to monitor iron overload management and to improve the outcomes of treatment, to enhance preventive strategies, reduce healthcare burden and improve the quality of life. Sustainability of the Malaysian Thalassaemia Registry is important for surveillance of thalassaemia management in the country and help the national health authorities to develop more effective policies.…”
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21093
Targeting the G-quadruplex as a novel strategy for developing antibiotics against hypervirulent drug-resistant Staphylococcus aureus
Published 2025-02-01“…The limited number of established targets further restricts the identification of novel antibiotics to treat life-threatening MDR infections caused by Staphylococcus aureus strains. …”
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21094
Open-source code for analysis of the lifetime total physical activity questionnaire (LTPAQ)
Published 2025-01-01“…By facilitating the processing of physical activity data from this questionnaire, our tool is expected to encourage its application in epidemiological studies and foster new insights into the impact of lifestyle from a life course perspective, ultimately playing a crucial role in shaping public health policies and enhancing clinical practice.…”
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21095
Effectiveness–implementation hybrid-2 randomised trial of a collaborative Shared Care Model for Detecting Neurodevelopmental Impairments after Critical Illness in Young Children (D...
Published 2022-07-01“…Introduction In Australia, while paediatric intensive care unit (PICU) mortality has dropped to 2.2%, one in three survivors experience long-term neurodevelopmental impairment, limiting their life-course opportunities. Unlike other high-risk paediatric populations, standardised routine neurodevelopmental follow-up of PICU survivors is rare, and there is limited knowledge regarding the best methods. …”
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21096
Pengaruh Edible Coating Berbasis Kitosan, Ekstrak Aloe Vera Dengan Penambahan Pektin Jeruk Terhadap Masa Simpan Buah Pir Potong
Published 2025-01-01“…Quality tests were then carried out, including weight loss, pH, vitamin C content, total dissolved solids and organoleptics.The results showed that edible coatings significantly reduced weight loss, maintained total soluble solid, pH, vitamin C content, and organoleptic quality, extending the shelf life of sliced pears compared to untreated pears (control). …”
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21097
Evaluasi TKTI Puri Saron Hotel Seminyak dengan Framework Cobit 5
Published 2023-10-01“…The findings of the analysis are centered on the COBIT Process, specifically the domains (EDM04) IT Resources, (APO01) Consistency Management, (APO03) IT Architecture, (APO04) IT Innovation, (APO07) Resource Management, (BAI04) Balancing Flows and Future Needs , (BAI09) Company Assets, (BAI10) Configuration Management, (DSS01) Operations Management, (DSS03) Managing Company Life Cycle Problems, and ( The process of planning, assessing and adjusting Puri Saron Hotel Seminyak for a better direction, and most of the domain activities have been executed, policies and norms have been written, and communication has improved. …”
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21098
Pengaruh Pesan Keagamaan Dalam Nadham Maulid Al-Dhiyâ’ Al-Lâmi’ Terhadap Jamaah Majelis Taklim Al-Hidayat Gampong Peulanggahan Banda Aceh; Kajian Ritual Effect
Published 2024-08-01“…The findings are as follows: First, the content includes messages of monotheism, praise for the Prophet, nobility, lineage, praises for the birth, and prophetic history; second, the religious impact on the lives of the congregation and the Acehnese community includes increased faith, love for the Prophet, adherence to Allah’s Sharia and the Prophet’s Sunnah, blessed life, improved morals, psychological therapy, and strengthened social relationships; third, the ritual art of reciting Nadham Maulid Al-Dhiyâ’ Al-Lâmi’ can be preserved due to the attraction to the familial network of the Prophet known as Ahlul Bait, as well as the traditional Hadrah music تركز هذه الدراسة على تحليل الرسائل الدينية في الطقوس القرائية لنظم مولد الضياء اللامع، وتأثيره على جماعة مجلس التعليم الهدى والمجتمع، وكذلك دوافع واستراتيجيات الحفاظ عليه باستخدام نهج تأثير الطقوس. …”
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21099
Endothelial calcium firing mediates the extravasation of metastatic tumor cells
Published 2025-02-01“…Summary: Metastatic dissemination is driven by genetic, biochemical, and biophysical cues that favor the distant colonization of organs and the formation of life-threatening secondary tumors. We have previously demonstrated that endothelial cells (ECs) actively remodel during extravasation by enwrapping arrested tumor cells (TCs) and extruding them from the vascular lumen while maintaining perfusion. …”
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21100
Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy
Published 2025-02-01“…IntroductionRheumatoid arthritis (RA) primarily affects the joints but can also affect multiple organs and profoundly impacts patients’ ability to carry out daily activities, mental health, and life expectancy. Current treatments for RA are limited in terms of duration, efficacy, and adverse effects. …”
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