Non-enzymatic protein targeting agents as a promising strategy for cancer treatment by Madison Ambrose, Jeremy Lee, Aleem Syed, Zamal Ahmed, Guang Peng

“…To efficiently identify potential chemical leads for these approaches, high-throughput screening (HTS) has been extremely valuable due to its ability to quickly screen large libraries of compounds. In this review paper, we will provide an overview of developing anti-cancer agents targeting non-enzymatic activities of proteins and the potential clinical impact of this new class of inhibitors.…”
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Raiding nature’s genetic toolbox for UV-C resistance by functional metagenomics by Garrett A. Roberts Kingman, Justin L. Kipness, Lynn J. Rothschild

“…We address a key gap in functional metagenomics work by exploring the impact of the experimental parameters chosen for functional metagenomics libraries. Experimental design dictates both fragment size and copy number, and we show that both can have outsized effects on the resultant phenotypes in non-intuitive ways. …”
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Phylogeography of the woolly mammoth (<i>Mammuthus primigenius</i>) in the Minusinsk Depression of southern Siberia in the Late Pleistocene by S. A. Modina, M. A. Kusliy, D. G. Malikov, A. S. Molodtseva

“…Within the framework of this effort, libraries for high-throughput sequencing of seven bone samples of woolly mammoths were obtained, two-round enrichment using biotinylated probes of modern mtDNA of Elephas maximus immobilised on magnetic microspheres and sequencing with subsequent bioinformatic analysis were carried out. …”
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Interplay of Transcriptomic Regulation, Microbiota, and Signaling Pathways in Lung and Gut Inflammation-Induced Tumorigenesis by Beatriz Andrea Otálora-Otálora, César Payán-Gómez, Juan Javier López-Rivera, Natalia Belén Pedroza-Aconcha, Sally Lorena Arboleda-Mojica, Claudia Aristizábal-Guzmán, Mario Arturo Isaza-Ruget, Carlos Arturo Álvarez-Moreno

“…A transcriptomic analysis of five pulmonary arterial hypertension, twelve Crohn’s disease, and twelve ulcerative colitis high throughput sequencing datasets using R language specialized libraries and gene enrichment analyses identified a regulatory network in each inflammatory disease. …”
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Synthetic Peptides as Potential Antigens for Cutaneous Leishmaniosis Diagnosis by Juliana Seger Link, Silvana Maria Alban, Carlos Ricardo Soccol, Gilberto Vinicius Melo Pereira, Vanete Thomaz Soccol

“…In order to reach the goal, we used random peptide phage display libraries screened using antibodies from Leishmania braziliensis patients. …”
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Bergenin, a bioactive flavonoid: advancements in the prospects of anticancer mechanism, pharmacokinetics and nanoformulations by Pratibha Pandey, Pratibha Pandey, Sorabh Lakhanpal, Danish Mahmood, Han Na Kang, Byunggyu Kim, Sojin Kang, Jinwon Choi, Seungjoon Moon, Shivam Pandey, Suhas Ballal, Sanjay Kumar, Fahad Khan, Bonglee Kim

“…Natural products are used as initial compounds to create combinatorial libraries by targeted modifications and then by analyzing their structure-activity connections. …”
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The effect of micro climate factors on energy consumption optimization approach in Tehran urban buildings by pariz Amiri Ade, Saeed Tizghalam zenozi, Mehrdad Javidi Nejad

“…The present study is of applied purpose and analytical method. Libraries and documents were used to collect the required data. …”
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Molecular Identification of Fungal Communities in a Soil Cultivated with Vegetables and Soil Suppressiveness to Rhizoctonia solani by Silvana Pompéia Val-Moraes, Eliamar Aparecida Nascimbem Pedrinho, Eliana Gertrudes Macedo Lemos, Lucia Maria Carareto-Alves

“…This metagenomic DNA was used as a template to amplify fungal 18S rDNA sequences, and libraries were constructed in Escherichia coli by cloning PCR products. …”
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A Critical Analysis of the Book New Criticism of Story, Novel and Narrative in Arabic Literature by Payman Salehi

“…The great tendency of contemporary Arab fiction literature critics to new approaches of Western criticism, especially in the last decade of the twentieth century and concerns about the severance of their relationship with the old Arabic critique and the urgent need of Arab libraries for works on criticism of critiques, made the Syrian Abu Heif to write the book “New Criticism of Story, Novel and Narrative in Arabic Literature”. …”
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Alkaloids Profiling of Fumaria capreolata by Analytical Platforms Based on the Hyphenation of Gas Chromatography and Liquid Chromatography with Quadrupole-Time-of-Flight Mass Spect... by María del Mar Contreras, Noureddine Bribi, Ana María Gómez-Caravaca, Julio Gálvez, Antonio Segura-Carretero

“…The use of these mass analyzers enabled tentatively identifying the alkaloids by matching their accurate mass signals and suggested molecular formulae with those previously reported in libraries and databases. Moreover, the proposed structures were corroborated by studying their fragmentation pattern obtained by both platforms. …”
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Energy Management Strategies for Smart Green MicroGrid Systems:  A Systematic Literature Review by Chaimaa Essayeh, Mohammed Raiss El-Fenni, Hamza Dahmouni, Mohamed Aymane Ahajjam

“…The selection process was based on an automated search and covered three known digital libraries. The extraction process covers three main questions. …”
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Prospective de novo drug design with deep interactome learning by Kenneth Atz, Leandro Cotos, Clemens Isert, Maria Håkansson, Dorota Focht, Mattis Hilleke, David F. Nippa, Michael Iff, Jann Ledergerber, Carl C. G. Schiebroek, Valentina Romeo, Jan A. Hiss, Daniel Merk, Petra Schneider, Bernd Kuhn, Uwe Grether, Gisbert Schneider

“…It enables the “zero-shot" construction of compound libraries tailored to possess specific bioactivity, synthesizability, and structural novelty. …”
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Transcriptome Analysis of the Thymus in Short-Term Calorie-Restricted Mice Using RNA-seq by Zehra Omeroğlu Ulu, Salih Ulu, Soner Dogan, Bilge Guvenc Tuna, Nehir Ozdemir Ozgenturk

“…RNA-seq-based transcriptome sequencing was performed to thymus tissues of MMTV-TGF-α mice subjected to ad libitum (AL), chronic calorie restriction (CCR), and intermittent calorie restriction (ICR) diets in this study. Three cDNA libraries were sequenced using Illumina HiSeq™ 4000 to produce 100 base pair-end reads. …”
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Indigofera suffruticosa Mill. (Anil): Plant Profile, Phytochemistry, and Pharmacology Review by Janaina K. L. Campos, Tiago F. da S. Araújo, Thaíse G. da S. Brito, Ana P. S. da Silva, Rebeca X. da Cunha, Mônica B. Martins, Nicácio H. da Silva, Bianka S. dos Santos, César A. da Silva, Vera L. de M. Lima

“…Information on I. suffruticosa was gathered via the Internet (from Elsevier, NCBI, and Sci-Hub) and libraries in the period from February to March 2016. …”
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Which aspects of neighbourhood environment are most associated with meeting physical activity recommendations in American adults: an NHIS study by Leigh F Callahan, Sarah C Gebauer, Joanne Salas, Jeffrey Scherrer

“…Other elements associated with meeting PA were presence of bus or transit stops to walk to and presence of movies, libraries or churches to walk to (OR=1.12 (95% CI 1.03 to 1.23) and OR=1.19 (95% CI 1.08 to 1.31), respectively).Conclusions In this analysis, the characteristic most strongly associated with PA was presence of places to walk and relax. …”
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Estonian book historiography by Mare Lott

“…During the post-war period, there was no leading center for book study, and the research concentrated at the major libraries. The problems of book history and research were also studied in the Department of Bibliography, first at Tartu University and then at Tallinn Pedagogical Institute. …”
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FACS‐Sortable Triple Emulsion Picoreactors for Screening Reactions in Biphasic Environments by Samuel Thompson, Yanrong Zhang, Zijian Yang, Lisa Nichols, Polly M. Fordyce

“…These triple emulsion picoreactors have the potential for future screening bead‐encoded catalyst libraries, including enzymes such as lipases for biofuel production.…”
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Potential plant extinctions with the loss of the Pleistocene mammoth steppe by Jérémy Courtin, Kathleen R. Stoof-Leichsenring, Simeon Lisovski, Ying Liu, Inger Greve Alsos, Boris K. Biskaborn, Bernhard Diekmann, Martin Melles, Bernd Wagner, Luidmila Pestryakova, James Russell, Yongsong Huang, Ulrike Herzschuh

“…While the robustness of the estimates will increase as DNA reference libraries and ancient sedaDNA data expand, the available data support that plants are more resilient to environmental changes than mammals.…”
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Big Data Analysis Using Apache Spark MLlib and Hadoop HDFS with Scala and Java by Hoger Khayrolla Omar, Alaa Khalil Jumaa

“…Apache Spark is another tool that developed and established to be the real model for analyzing big data with its innovative processing framework inside the memory and high-level programming libraries for machine learning, efficient data treating and etc. …”
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Expression Analysis of Sugarcane Aquaporin Genes under Water Deficit by Manassés Daniel da Silva, Roberta Lane de Oliveira Silva, José Ribamar Costa Ferreira Neto, Ana Carolina Ribeiro Guimarães, Daniela Truffi Veiga, Sabrina Moutinho Chabregas, William Lee Burnquist, Günter Kahl, Ana Maria Benko-Iseppon, Ederson Akio Kido

“…Forty-two distinct aquaporin isoforms were expressed in four HT-SuperSAGE libraries from sugarcane roots of drought-tolerant and -sensitive genotypes, respectively. …”
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