Lucidin from <i>Rubia cordifolia</i> Outperforms FDA-Approved Lapatinib as a Potential Multitargeted Candidate for Breast Cancer Signalling Proteins by Akram Ahmed Aloqbi, Hadil Alahdal, Amany I. Alqosaibi, Mashael M. Alnamshan, Ibtesam S. Al-Dhuayan, Ahood A. Al-Eidan, Hind A. S. Alzahrani, Nouf K. ALaqeel, Fatmah Hazza Alsharif, Abeer Al Tuwaijri

“…<b>Methods:</b> We performed multitargeted molecular docking studies on key breast cancer proteins using a natural compound library from ZINC. Comparative analyses of Lucidin and Lapatinib included molecular interaction fingerprints, pharmacokinetics, WaterMap computations (5 ns) to assess water thermodynamics and binding interactions, and Molecular Dynamics Simulations (100 ns) in water to evaluate complex stability and dynamic behaviour. …”
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SARS-CoV-2 active infection and antibodies amongst health personnel during the outbreak in Cameroon: Strengthening the health system for response to future public health emergencie... by Sen Claudine Henriette Ngomtcho, Blaise Mboringong Akenji, Ketina Hirma Tchio-Nighie, Joseph Fokam, Etienne Guenou, Carolle Nsa'Amang Eyebe, Yvan Junior Nzegni Kamkoum, Valdex Derick Ntale Tchoffo, Collins Buh Nkum, Hervé Christian Tchoudjin Paho, Yvette Marie Solange Ebogo, Aude Nanfak, Martin Maidadi-Foudi, Crescence Fouda, Angyiba Serge Andigema, Lilian Nsah Bongdze-Em, Beri Nadin Nfor, Judith Torimiro, Anne Cécile Zoung-Kanyi Bissek, Michel Noubom, Marie Claire Assoumou Okomo, Jérôme Ateudjieu

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Scrub typhus in pregnancy: A 10-year multicenter study in resource-limited settings in China. by Peilin Zhao, Tieyong Dong, Hongbin Lu, Rui Zhu, Shanshan Zhao, Wuqian Tao, Li Li, Chunmei Liu, Shuwei Pu, Ling Mo, Huanhuan Wang

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Design and Application of a Data-computation Integrated Database for Meteorological Grid Data by Wang Shu, Xu Yongjun, He Wenchun, Wu Huanping, Gao Feng, Liu Yuanyuan, Liu Bei, Lü Guanru, Ni Xuelei

“…To address these issues, National Meteorological Information Center has developed PostGrid, an integrated database for meteorological gridded data and computing, based on Tianqing Spatial Analysis Library and is specifically designed for distributed environments. …”
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Comparison of efficacy and safety of thrombus prevention strategies after abdominal and pelvic cancer surgery: Bayesian network based meta-analysis by Shiran Qin, Shiran Qin, Sitong Guo, Yucheng Yao, Yucheng Yao, Ying He, Dandan Xu, Dandan Xu, Henghai Su, Xiaoyu Chen, Haoru Meng

“…However, there is insufficient evidence supporting the choice of anticoagulation strategies.MethodsWe searched PubMed, The Cochrane Library, Embase, and Web of Science for randomized controlled trials from inception to January 2024. …”
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Perceived benefits and challenges one year after receiving brief therapy in a district psychiatric centre. An exploration of patients' and GPs' experiences: A qualitative study. by Hilde V Markussen, Lene Aasdahl, Petter Viksveen, Marit B Rise

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Transition to home after very preterm birth: improving outcomes of children and their families—a systematic review protocol by Beatrice Latal, Ulrike Held, Ursula Kiechl-Kohlendorfer, Sandra Siegfried, Vivienne Engel, Valentina Mauron-Papadimitriou, Lea Bührer, Laura Ebner, Lena Keller, Martina Gosteli

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Review protocol for a systematic review and meta-analysis on HIV inequities in transgender and non-binary populations by Jennifer Sherwood, Arjee Restar, Don Operario, Hannah Rogers, Ruby Lucas, Ruwenne Moodley, Jessie M. Garcia Gutiérrez, Audren J K Bambilla, Dil Singh, Emerson Dusic, Danielle Giovenco, Shufang Sun

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A systematic review of Streptococcus Mutans and Veillonellae species interactions in dental caries progression: Positive or Negative impact? [version 2; peer review: 1 approved, 2... by Faizul Hasan, Prawati Nuraini, Ariadna Adisattya Djais, Ervina Restiwulan Winoto, Tantiana Tantiana, Rini Devijanti Ridwan, Juni Handajani, Rajesh Ramasamy, Silvia Anitasari, Hendrik Setia Budi

“…Three electronic databases, namely PubMed, Embase, and the Cochrane library, were used to conduct a systematic search for eligible studies from their inception until July 18, 2023. …”
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Effects of Corporal Punishments on Pupils Learning of English in Selected Primary Schools in Kyanamira Sub-County Kabale District Western Uganda. by Tumwijukye, Wencesilous

“…Respondents said 40 (20%) teachers should use effective participatory methods in teaching, 36 (18%) suggested that schools should take pupils on study tours, 56 (28%) pupils should have enough group discussions, 24 (12%) said learners should be provided with regular assignment, also 16 (8%) suggested schools should have guidance and counseling services, 12 (6%) said there should be remedial classes, 16 (8%) suggested effective use of library. Table 12.14 summarizes the results. From the findings and conclusions of the study, the following recommendations have been made to reduce the use of corporal punishment as the solution to academic performance in primary schools. …”
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Leave no child behind: Using data from 1.7 million children from 67 developing countries to measure inequality within and between groups of births and to identify left behind popul... by Antonio P Ramos, Martin J Flores, Robert E Weiss

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Prevalence and related factors of compassion fatigue among registered nurses and nursing students during the internship: a systematic review and meta-analysis by Lijuan Yi, Suwen Hu, Mengqi Liao, Liang Cheng, Yi Liu, Xu Tian, Maria F. Jiménez-Herrera

“…Literature searches were conducted in five databases (Cochrane Library, PubMed, EMBASE, CNKI, and WanFang) up to November 30, 2022, with updates planned until January 17, 2024, if necessary. …”
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Effects of practical models of low-volume high-intensity interval training on glycemic control and insulin resistance in adults: a systematic review and meta-analysis of randomized... by Yining Lu, Julien S. Baker, Shanshan Ying, Yichen Lu

“…ObjectivesThe aim of this systematic review and meta-analysis was to investigate the effects of practical models of low-volume high-intensity interval training protocols (LV-HIIT) on glucose control and insulin resistance compared with moderate-intensity continuous training (MICT) protocols and no-exercise controls (CON).MethodsFour databases (PubMed, Web of Science, Scopus, and Cochrane Library) were searched for randomized controlled studies conducted using LV-HIIT interventions (HIIT/SIT protocols involving ≤ 15 min of intense training, within a session lasting ≤ 30 min; &lt; 30 s all-out sprint for SIT additionally). …”
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Comparison of Robot-Assisted, Laparoscopic, and Open Radical Prostatectomy Outcomes: A Systematic Review and Network Meta-Analysis from KSER Update Series by Do Kyung Kim, Young Joon Moon, Doo Yong Chung, Hae Do Jung, Seung Hyun Jeon, Seok Ho Kang, Sunghyun Paick, Joo Yong Lee

“…<i>Materials and Methods:</i> A comprehensive literature search was performed in Pubmed, EMBASE, and the Cochrane library for papers published before May 2021. Only studies of patients with prostate cancer that assessed perioperative, functional, and oncological outcomes and reported outcome values were included. …”
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Point prevalence survey of antibiotic use in Mexican secondary care hospitals. by Federico A Zumaya-Estrada, Celia M Alpuche-Aranda, Hilda Ivonne Huerta Icelo, Felipe D Neri-Estrada, Verónica M Calixto Silva, Haydee E Quiroz Escoriza, Jesus Ulises Garza-Ramos, Pedro J Saturno-Hernandez

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Study on the impact of Kinesiophobia after Total Knee Arthroplasty on the rehabilitation of patients during hospitalization: A pilot study. by Yichao Yao, Qi Zhang, Shaoning Cui, Xumeng Guo

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Efficacy and safety of the pulsed electromagnetic field in osteoarthritis: a meta-analysis by Ziying Wu, Xiang Ding, Guanghua Lei, Chao Zeng, Jie Wei, Jiatian Li, Hui Li, Tuo Yang, Yang Cui, Yilin Xiong, Yilun Wang, Dongxing Xie

“…Objective To investigate the efficacy and safety of the pulsed electromagnetic field (PEMF) therapy in treating osteoarthritis (OA).Design Meta-analysis.Data sources PubMed, Embase, the Cochrane Library and Web of Science were searched through 13 October 2017.Eligibility criteria for selecting studies Randomised controlled trials compared the efficacy of PEMF therapy with sham control in patients with OA.Data extraction and synthesis Pain, function, adverse effects and characteristics of participants were extracted. …”
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Clinical benefits of modifying the evening light environment in an acute psychiatric unit: A single-centre, two-arm, parallel-group, pragmatic effectiveness randomised controlled t... by Håvard Kallestad, Knut Langsrud, Melanie Rae Simpson, Cecilie Lund Vestergaard, Daniel Vethe, Kaia Kjørstad, Patrick Faaland, Stian Lydersen, Gunnar Morken, Ingvild Ulsaker-Janke, Simen Berg Saksvik, Jan Scott

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Replication of European hypertension associations in a case-control study of 9,534 African Americans. by Harpreet Kaur, Dana C Crawford, Jingjing Liang, Penelope Benchek, COGENT BP Consortium, Xiaofeng Zhu, Asha R Kallianpur, William S Bush

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Impacts of stem cells from different sources on wound healing rate in diabetic foot ulcers: a systematic review and meta-analysis by Le Tong, Le Tong, Le Tong, Lin Tang, Lin Tang, Lin Tang, Bangli Tang, Jianna Zhang, Jianna Zhang, Jianna Zhang

“…The objective of this meta-analysis was to evaluate the impacts of stem cells from different sources on wound healing rate in DFU patients.MethodsWe systematically retrieved records via key databases PubMed, Cochrane Library, Web of Science, Embase, China National Knowledge Infrastructure (CNKI) and Wanfang from the inception to October 2024. …”
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