Combined blockade of GPX4 and activated EGFR/HER3 bypass pathways inhibits the development of ALK‐inhibitor‐induced tolerant persister cells in ALK‐fusion‐positive lung cancer... by Koh Furugaki, Takaaki Fujimura, Narumi Sakaguchi, Yasutaka Watanabe, Ken Uchibori, Eisaku Miyauchi, Hidetoshi Hayashi, Ryohei Katayama, Shigeki Yoshiura

“…We generated alectinib‐induced DTP cells from a patient‐derived ALK+ non‐small‐cell lung cancer (NSCLC) cell line and screened 3114 agents in the anticancer compounds library (TargetMol). We identified phospholipid hydroperoxide glutathione peroxidase GPX4 as being involved in promoting the survival of DTP cells. …”
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Need to clamp indwelling urinary catheters before removal after different durations: a systematic review and meta-analysis by Xiaoyan Fan, Sumin Ma, Jiayi Gu

“…Objective This meta-analysis aimed to evaluate the effect of bladder training by clamping on bladder urethral function in patients with indwelling urinary catheters used for different durations.Design Systematic review and meta-analysis.Data sources The UpToDate, Cochrane Library, OVID, PubMed, China National Knowledge Infrastructure, CINAHL and Embase were screened from 1 January 2000 to 28 February 2022.Eligibility criteria for selecting studies Randomised controlled trials (RCTs) or quasi-experimental designs comparing the efficacy of bladder training in patients with an indwelling urinary catheter by clamping or free drainage before urinary catheter removal were published in English or Chinese.Data extraction and synthesis Two reviewers independently extracted the data and assessed the quality of studies. …”
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F-box protein Fbx23 acts as a transcriptional coactivator to recognize and activate transcription factor Ace1. by Zhongjiao Liu, Kexuan Ma, Panpan Zhang, Siqi Zhang, Xin Song, Yuqi Qin

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Causal relationship between ulcerative colitis and male infertility: A two-sample Mendelian randomization study. by Xia Wang, Tongyi Li, Qiu Chen

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The Role of Probiotics in Managing Glucose Homeostasis in Adults with Prediabetes: A Systematic Review and Meta-Analysis by Chao Sun, Qingyin Liu, Xiaona Ye, Ronghua Li, Miaomiao Meng, Xingjun Han

“…A comprehensive literature search of the PubMed, Embase, and Cochrane Library databases was conducted through August 2022 to assess the impact of probiotics on blood glucose, lipid, and inflammatory markers in adults with prediabetes. …”
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BIOMECHANICAL EVALUATIONS OF IMPLANTO-PROSTHETIC RESTORATIONS by Resmerita Andreea, Cretu Cosmin Ionut, Scheuleac Alexandra, Agop-Forna Doriana, Adam Eduard, Forna Norina

“…Databases searched included PubMed, Cochrane Library, and Web of Science. Studies were selected based on specific inclusion and exclusion criteria, and data were extracted and analyzed using standard meta-analytic techniques. …”
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LincRNA Cox-2 Regulates Lipopolysaccharide-Induced Inflammatory Response of Human Peritoneal Mesothelial Cells via Modulating miR-21/NF-κB Axis by Yaoyao Bian, Lili Yang, Bin Zhang, Wen Li, Sen Wang, Shuling Jiang, Xi Chen, Wenlin Li, Li Zeng

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Efficacy and safety of pembrolizumab in patients with advanced endometrial cancer: a systematic review and meta-analysis by Biqiong Pan, Xiaojun Lai, Jiefang Lu, Xiaoyan Bao, Zengke Fan, Jie Sun

“…ObjectiveThis meta-analysis evaluated pembrolizumab monotherapy and combination therapy’s efficacy and safety in recurrent or advanced endometrial cancer (EC).MethodsWe utilized PubMed, Embase, Cochrane Library, and Web of Science databases to identify clinical trials that were used to search literature from July 2013 to July 2023 to evaluate the efficacy and safety of pembrolizumab in patients with advanced EC. …”
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Risk reduction in SARS-CoV-2 infection and reinfection conferred by humoral antibody levels among essential workers during Omicron predominance. by James Hollister, Cynthia Porter, Ryan Sprissler, Shawn C Beitel, James K Romine, Jennifer L Uhrlaub, Lauren Grant, Young M Yoo, Ashley Fowlkes, Amadea Britton, Lauren E W Olsho, Gabriella Newes-Adeyi, Sammantha Fuller, Pearl Q Zheng, Manjusha Gaglani, Spencer Rose, Kayan Dunnigan, Allison L Naleway, Lisa Gwynn, Alberto Caban-Martinez, Natasha Schaefer Solle, Harmony L Tyner, Andrew L Philips, Kurt T Hegmann, Sarang Yoon, Karen Lutrick, Jefferey L Burgess, Katherine D Ellingson

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Prevalence of HIV infection and uptake of HIV/AIDs services among fishermen on the shores of Lake Victoria in Kagera region, Northwestern Tanzania. by Patrick Mwanahapa, Mtoro J Mtoro, Dina Gerald, Pius Horumpende, Salaam Mujeeb

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The RNA-binding protein Puf5 and the HMGB protein Ixr1 regulate cell cycle-specific expression of CLB1 and CLB2 in Saccharomyces cerevisiae. by Megumi Sato, Varsha Rana, Yasuyuki Suda, Tomoaki Mizuno, Kenji Irie

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A systematic scoping review of latent class analysis applied to accelerometry-assessed physical activity and sedentary behavior. by Michael Kebede, Annie Green Howard, Yumeng Ren, Blake Anuskiewicz, Chongzhi Di, Melissa A Troester, Kelly R Evenson

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Effectiveness of Digital Mental Health Interventions in the Workplace: Umbrella Review of Systematic Reviews by Gillian Cameron, Maurice Mulvenna, Edel Ennis, Siobhan O'Neill, Raymond Bond, David Cameron, Alex Bunting

“…The following databases were searched: PubMed, Web of Science, MEDLINE, PsycINFO, and Cochrane Library. Data were extracted using a predefined extraction table. …”
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Comparison of the Efficacy and Safety of Intravitreal Conbercept with Intravitreal Ranibizumab for Treatment of Diabetic Macular Edema: A Meta-Analysis by Xiaolei Sun, Jingjing Zhang, Jingyi Tian, Shijiu Chen, Fanxing Zeng, Gongqiang Yuan

“…Relevant studies were identified through systemic searches of PubMed, Embase, Cochrane Library, Ovid, CNKI, and Wanfang database up to 28 February 2019. …”
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Tibiofemoral Joint Contact Force Estimation Based on OpenSim Musculoskeletal Modeling by WANG Xiaoling, JIAN Jiawei, XIE Qiurong, LIAN Zhanghui, GUO Chunming, GUO Jiemei, LI Yurong

“…Based on the general musculoskeletal model gait2392 in the OpenSim model library, the tibial-femoral joint is adjusted from a single contact point to a double contact point, and the knee joint structure is adjusted to have three directional degrees of freedom. …”
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Disentangling the effects of intermittent faecal shedding and imperfect test sensitivity on the microscopy-based detection of gut parasites in stool samples. by Lana C E Ferreira-Sá, Eleuza R Machado, Rodrigo Gurgel-Gonçalves, Fernando Abad-Franch

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Pulmonary Bacterial Communities in Surgically Resected Noncystic Fibrosis Bronchiectasis Lungs Are Similar to Those in Cystic Fibrosis by Heather Maughan, Kristopher S. Cunningham, Pauline W. Wang, Yu Zhang, Marcelo Cypel, Cecilia Chaparro, D. Elizabeth Tullis, Thomas K. Waddell, Shaf Keshavjee, Mingyao Liu, David S. Guttman, David M. Hwang

“…Bacterial 16S rRNA gene libraries were constructed from lung tissue of 10 non-CF bronchiectasis and 21 CF patients, followed by DNA sequencing of isolates from each library. …”
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The invisible enemy: A systematic review and meta-analysis of maternal smokeless tobacco use as a risk factor for low birth weight. by Akanksha Mahajan, Bhawna Gupta, Michael Tong

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Optimising primary molecular profiling in non-small cell lung cancer. by R D Schouten, I Schouten, M M F Schuurbiers, V van der Noort, R A M Damhuis, E H F M van der Heijden, J A Burgers, N P Barlo, A S R van Lindert, K W Maas, J J G van den Brand, A A J Smit, J M W van Haarst, B van der Maat, E Schuuring, H Blaauwgeers, S M Willems, K Monkhorst, D van den Broek, M M van den Heuvel

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Feasibility of a pragmatic randomized adaptive clinical trial to evaluate a brief negotiational interview for harmful and hazardous alcohol use in Moshi, Tanzania. by Catherine A Staton, Kaitlyn Friedman, Ashley J Phillips, Mary Catherine Minnig, Francis M Sakita, Kennedy M Ngowi, Brian Suffoletto, Jon Mark Hirshon, Monica Swahn, Blandina T Mmbaga, Joao Ricardo Nickenig Vissoci

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