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Discovery and Characterization of Two Selective Inhibitors for a Mu-Class Glutathione S-Transferase of 25 kDa from <i>Taenia solium</i> Using Computational and Bioinformatics Tools
Published 2024-12-01“…Representative structures from these simulations and a putative binding site with low conservation relative to human GSTs, identified via the SILCS methodology, were employed for virtual screening through ensemble docking against a commercial compound library. The two compounds were found to reduce the enzyme’s activity by 50–70% under assay conditions, while showing a reduction of only 30–35% for human mu-class GSTM1, demonstrating selectivity for Ts25GST. …”
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Discovery and Characterization of Novel Esterases with Ethyl Carbamate-Hydrolyzing Activity
Published 2025-01-01“…The EC-degrading esterases had good ethanol tolerance, which not only enrich the EC-hydrolyzing enzyme library, but also provide a new method for controlling the EC content in traditional fermented foods with low alcohol content.…”
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Costs of outpatient services at selected primary healthcare centers in Bangladesh: A cross-sectional study.
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A scoping review of interventions to improve strength training participation.
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Integrated microRNA and mRNA signatures associated with overall survival in epithelial ovarian cancer.
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Sustainable Distance E-Learning for Enhanced Students Retention and Support: Faculty of Law National Open University of Nigeria in Focus
Published 2016-07-01“…Strategies proffered to remedy the situation include pre-enrolment orientation in e-Learning environment and mentoring, improved budgetary allocation, improved ICT facilities including e-library, follow-up on students and proper staffing amongst others. …”
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AI enabled, mobile soil pH classification with colorimetric paper sensors for sustainable agriculture.
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Nurses' use of social media during the COVID-19 pandemic-A scoping review.
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A comparative analysis and survival analysis of open versus minimally invasive radical antegrade modular pancreatosplenectomy for pancreatic cancer: a systematic review and meta-an...
Published 2025-01-01“…Data were extracted from EMBASE, PubMed, and the Cochrane Library databases through September 16, 2023. The ROBINS-I tool was used to assess the risk of bias. …”
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