Expression of Leptin Receptor and Effects of Leptin on Papillary Thyroid Carcinoma Cells by Marilena Celano, Valentina Maggisano, Saverio Massimo Lepore, Marialuisa Sponziello, Valeria Pecce, Antonella Verrienti, Cosimo Durante, Marianna Maranghi, Piernatale Lucia, Stefania Bulotta, Giuseppe Damante, Diego Russo

“…In this translational study, we analyzed in vitro the effects of leptin on the growth and migration of thyroid cancer cells (TPC-1 and K1), the molecular mechanisms underlying leptin’s action, and the influence of prolonged leptin exposure on cell response to a protein kinase inhibitor lenvatinib. …”
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Leptin Promotes Glioblastoma by Johnathan E. Lawrence, Nicholas J. Cook, Richard A. Rovin, Robert J. Winn

“…The hormone leptin has a variety of functions. Originally known for its role in satiety and weight loss, leptin more recently has been shown to augment tumor growth in a variety of cancers. …”
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Leptin as well as Free Leptin Receptor Is Associated with Polycystic Ovary Syndrome in Young Women by Nasser M. Rizk, Elham Sharif

“…The soluble leptin receptor (sOB-R) circulates in the blood and can bind to leptin. …”
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Obesity Hypertension: The Regulatory Role of Leptin by Shilpa Kshatriya, Kan Liu, Ali Salah, Tamas Szombathy, Ronald H. Freeman, Garry P. Reams, Robert M. Spear, Daniel Villarreal

“…Leptin is a 16-kDa-peptide hormone that is primarily synthesized and secreted by adipose tissue. …”
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Environment, Leptin Sensitivity, and Hypothalamic Plasticity by Marco Mainardi, Tommaso Pizzorusso, Margherita Maffei

“…Regulation of feeding behavior has been a crucial step in the interplay between leptin and the arcuate nucleus of the hypothalamus (ARC). …”
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Polymorphisms of Leptin (-2548 G/A) and Leptin Receptor (Q223R) Genes in Iranian Women with Breast Cancer by Reza Mahmoudi, Bahareh Noori Alavicheh, Mohammad Amin Nazer Mozaffari, Mohammad Fararouei, Mohsen Nikseresht

“…Recent studies have shown that polymorphisms in leptin and leptin receptor genes are associated with increased risk for breast cancer. …”
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Leptin Regulates Proliferation and Apoptosis in Human Prostate by Eduardo Leze, Jorge Luiz Alves-Pereira, Sicilia Colli, Fernanda Silveira Cavalcante, Francisco José Sampaio, Cristiane da Fonte Ramos

“…This paper aimed to evaluate the leptin role on the cellular proliferation and the expression of fibroblast growth factor 2, aromatase enzyme, and apoptotic genes in the human prostate tissue. …”
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Serum Leptin as a Marker for Severity of Endometriosis by Shatha Sami Hussein, Fatin Shallal Farhan, Alaa Ibrahim Ali

“…To test the role of serum leptin in determination of severity of endometriosis. …”
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Leptin Induces an Inflammatory Phenotype in Lean Wistar Rats by Monique Allman, Mathew Wallace, Latausha Gaskin, Chantal A. Rivera

“…The present study addressed the hypothesis that leptin promotes leukocyte trafficking into adipose tissue. …”
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Plasma Leptin Concentrations and Esophageal Hypomotility in Obese Patients by Justin Côté-Daigneault, Pierre Poitras, Rémi Rabasa-Lhoret, Mickael Bouin

“…It has been hypothesized that elevated plasma leptin concentration is a risk factor for esophageal dysmotility in obese patients.…”
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Leptin, Adiponectin, and Obesity among Caucasian and Asian Women by Shannon M. Conroy, Weiwen Chai, Unhee Lim, Adrian A. Franke, Robert V. Cooney, Gertraud Maskarinec

“…General linear models were used to estimate adjusted mean levels of leptin, adiponectin, interleukin-6, and C-reactive protein (CRP). …”
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Adiponectin and Leptin Metabolic Biomarkers in Chinese Children and Adolescents by Jie Mi, Mercedes Nancy Munkonda, Ming Li, Mei-Xian Zhang, Xiao-Yuan Zhao, Ponce Cedric Wamba Fouejeu, Katherine Cianflone

“…Objective. To evaluate leptin and adiponectin as biomarkers of metabolic syndrome (MS) risk factors even in nonobese children/adolescents. …”
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Leptin Enhances Synthesis of Proinflammatory Mediators in Human Osteoarthritic Cartilage—Mediator Role of NO in Leptin-Induced PGE2, IL-6, and IL-8 Production by Katriina Vuolteenaho, Anna Koskinen, Meiju Kukkonen, Riina Nieminen, Unto Päivärinta, Teemu Moilanen, Eeva Moilanen

“…In the present paper, the effects of leptin on human OA cartilage were studied. Leptin alone or in combination with IL-1 enhanced the expression of iNOS and COX-2, and production of NO, PGE2, IL-6, and IL-8. …”
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The Effects of Reduction Mammaplasty on Serum Leptin Levels and Insulin Resistance by Hakan Uzun, Ozan Bitik, Yahya Baltu, Çiğdem Sönmez, Ayşegül Öztürk Kaymak

“…A significant correlation between body mass index and leptin change was found postoperatively. Conclusion. …”
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Immunolabeling of leptin in the liver of Nile tilapia using the immunohistochemistry technique by M.O. Pereira, P.H.S. Ferro, A. Jatobá, D.D. Schleder, F. Moreira

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Polymorphisms in the leptin gene and their role in adolescent obesity and metabolic health by Raden Ayu Tanzila, Irfannuddin Irfannuddin, Yudianita Kesuma, Iche Andriyani Liberty, Miranti Dwi Hartanti, Ni Made Elva Mayasari, Wieke Anggraini, Liza Chairani, Thia Prameswarie, Indri Ramayanti, Wulan Aristi, Delvi Larasari

Subjects: “…leptin…”
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POLYMORPHISM OF GENES FOR SOMATOTROPIN, PROLACTIN, LEPTIN, AND THYROGLOBULIN IN STUD BULLS by S. V. Tjulkin, T. M. Ahmetov, E. F. Valiullina, R. R. Vafin

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Chronic Kidney Disease, Obesity, and Hypertension: The Role of Leptin and Adiponectin by M. Tesauro, A. Mascali, O. Franzese, S. Cipriani, C. Cardillo, N. Di Daniele

“…Among these adipocytokines, which represent a link between obesity, hypertension, and chronic nephropathy, leptins and adiponectin appear to play an important role. …”
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Hepatoportal Leptin Sensors and Their Reflex Effects on Autonomic Outflow in the Rat by Akira Niijima

“…Afferent nerve signals were recorded from a peripheral cut end of the small nerve bundle of the hepatic branch of the vagus nerve in anesthetized rats. An injection of leptin (100 pg, 0.1 mL) into the portal vein facilitated the afferent activity. …”
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Discriminatory Value of Adiponectin to Leptin Ratio for COVID-19 Pneumonia by Federica Tonon, Stefano Di Bella, Fabiola Giudici, Verena Zerbato, Ludovica Segat, Raffaella Koncan, Andrea Misin, Barbara Toffoli, Pierlanfranco D’Agaro, Roberto Luzzati, Bruno Fabris, Stella Bernardi

“…Patients with COVID-19 pneumonia had higher levels of leptin, lower adiponectin/leptin (Adpn/Lep) ratio, and higher expression of IL-6. …”
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