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Leptin Modifies the Rat Heart Performance Associated with Mitochondrial Dysfunction Independently of Its Prohypertrophic Effects
Published 2018-01-01“…Functional receptors for leptin were described on the surface of cardiomyocytes, and there was a prohypertrophic effect with high concentrations of the cytokine. …”
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Evaluation of serum leptin and adiponectin and their associations with obesity-related renal injury among Egyptian adolescents
Published 2023-12-01Subjects: Get full text
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43
Polymorphism in LEP and LEPR May Modify Leptin Levels and Represent Risk Factors for Thyroid Cancer
Published 2015-01-01“…Patients with AA genotype of rs7799039 had higher levels of serum leptin (9.22±0.98 ng/mL) than those with AG genotype (10.07±0.60 ng/mL; P=0.005). …”
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Diet-Induced Swine Model with Obesity/Leptin Resistance for the Study of Metabolic Syndrome and Type 2 Diabetes
Published 2012-01-01“…The objective of the present study was to determine the suitability of a swine breed with leptin resistance and predisposition to obesity (the Iberian pig) as model for studies on metabolic syndrome and type 2 diabetes. …”
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45
Chronic cholecystitis at patients with the various trophological status: mechanisms and feature of clinical course
Published 2014-09-01Subjects: Get full text
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46
Association of leptin receptor Gln223Arg genetic polymorphism with obesity and non-alcoholic fatty liver disease
Published 2014-09-01Subjects: “…leptin receptor gene…”
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47
Serum choline, leptin and interleukin-6 levels in fibromyalgia syndrome-induced pain: a case–control study
Published 2025-02-01Subjects: Get full text
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48
Association of Serum Adiponectin, Leptin, and Resistin Concentrations with the Severity of Liver Dysfunction and the Disease Complications in Alcoholic Liver Disease
Published 2013-01-01“…Acrp30 and resistin levels were significantly higher in patients with ALD than in controls. Lower leptin levels in females with ALD compared to controls, but no significant differences in leptin concentrations in males, were found. …”
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Leptin Receptor Deficiency Protects Mice against Chronic Cerebral Hypoperfusion-Induced Neuroinflammation and White Matter Lesions
Published 2020-01-01“…Leptin participates in the inflammatory responses in multiple cell types and animal models. …”
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Impaired inflammatory resolution with severe SARS-CoV-2 infection in leptin knock out obese hamster
Published 2025-02-01“…Here, we used gene-edited leptin knock out (Leptin−/−) obese hamsters to establish a severe infection model. …”
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Oral Findings, Salivary Copper, Magnesium, and Leptin in Type II Diabetic Patients in Relation to Oral Candida Species
Published 2024-01-01“…However, the variables being examined, such as body mass index (BMI), burning mouth syndrome (BMS), salivary flow rate (SFR), salivary leptin, salivary copper, and salivary magnesium, did not exhibit any significant variations in quantities between the diabetic and healthy groups (p>0.05). …”
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52
Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls
Published 2012-01-01“…BACKGROUND: Leptin, an adipocyte-produced cytokine, interacts with various hormones, including those of the hypothalamic-pituitary-adrenal axis. …”
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Single-Cell RNA Sequencing Reveals Macrophage Dynamics During MASH in <i>Leptin</i>-Deficient Rats
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54
Altered Hepatic Lipid Metabolism Contributes to Nonalcoholic Fatty Liver Disease in Leptin-Deficient Ob/Ob Mice
Published 2013-01-01“…Here we examined genes and proteins involved in hepatic oxidation and lipogenesis in 14-week-old leptin-deficient Ob/Ob mice, a commonly studied model of obesity and hepatic steatosis. …”
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Influence of leptin administration to pregnant female mice on obesity development, taste preferences, and gene expression in the liver and muscles of their male and female offspring
Published 2021-10-01Subjects: “…leptin…”
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56
Salivary Hormones Leptin, Ghrelin, Glucagon, and Glucagon-Like Peptide 1 and Their Relation to Sweet Taste Perception in Diabetic Patients
Published 2023-01-01“…DM may disrupt hormone regulation. Metabolic hormones, leptin, ghrelin, glucagon, and glucagon-like peptide 1, are produced by the salivary glands and taste cells. …”
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Does Q223R Polymorphism of Leptin Receptor Influence on Anthropometric Parameters and Bone Density in Childhood Cancer Survivors?
Published 2013-01-01“…Childhood cancer survivors are in augmented risk for developing obesity. For many factors leptin and leptin receptor gene polymorphism play an important role in the development and metabolism not only of fat, but also, bone tissue. …”
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Recombinant Human Leptin Does Not Alter Gut Hormone Levels after Gastric Bypass but May Attenuate Sweet Cravings
Published 2014-01-01“…Bariatric surgery improves glucose homeostasis and alters gut hormones partly independent of weight loss. Leptin plays a role in these processes; levels are decreased following bariatric surgery, creating a relative leptin insufficiency. …”
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Leptin Inhibits the Proliferation of Vascular Smooth Muscle Cells Induced by Angiotensin II through Nitric Oxide-Dependent Mechanisms
Published 2010-01-01“…This inhibitory effect of leptin was abolished by NOS inhibitor, NMMA, and iNOS selective inhibitor, L-NIL, and was not observed in leptin receptor-deficient fa/fa rats. …”
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Fasting Leptin Is a Metabolic Determinant of Food Reward in Overweight and Obese Individuals during Chronic Aerobic Exercise Training
Published 2014-01-01“…Furthermore, a greater exercise-induced decline in fasting leptin was associated with increased liking (P=0.018). …”
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