Peroxisome Proliferator-Activated Receptor-γ-Mediated Polarization of Macrophages in Leishmania Infection by Marion M. Chan, Nagasuresh Adapala, Cui Chen

“…Infection is the outcome of a contest between a pathogen and its host. In the disease leishmaniasis, the causative protozoan parasites are harbored inside the macrophages. …”
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YAT2150 is irresistible in Plasmodium falciparum and active against Plasmodium vivax and Leishmania clinical isolates by Inés Bouzón-Arnáiz, Mukul Rawat, Rachael Coyle, Lionel Brice Feufack-Donfack, Malen Ea, Agnes Orban, Jean Popovici, Lucía Román-Álamo, Antonino Nicolò Fallica, Bárbara Domínguez-Asenjo, Javier Moreno, Elsa M. Arce, Ana Mallo-Abreu, Diego Muñoz-Torrero, Marcus C. S. Lee, Xavier Fernàndez-Busquets

“…Tests performed in clinical isolates indicated that YAT2150 had also strong activity against Plasmodium vivax (IC50 between 4 and 36 nM) and Leishmania infantum (1.27 and 1.11 µM), placing it as a unique compound with perspectives of becoming the first drug to be used against both malaria and leishmaniasis.…”
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Dyarrheal Syndrome in a Patient Co-Infected with Leishmania infantum and Schistosoma mansoni by Gláucia Fernandes Cota, Luciana Inácia Gomes, Bruna Fernandes Pinto, Joanna R. Santos-Oliveira, Alda Maria Da-Cruz, Moisés Salgado Pedrosa, Wagner Luiz Tafuri, Ana Rabello

“…This case report describes an atypical clinical presentation of visceral leishmaniasis affecting the digestive tract and causing malabsorption syndrome in a patient without recognized immunosuppressive condition. …”
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Clinical and Epidemiological Features of Patients with Drug-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Iran: Different Points of Children from Adults by Bahareh Abtahi-Naeini, Mohammad-sadegh Dehghan, Fatemeh Paknazar, Zabihollah Shahmoradi, Gita Faghihi, Ali Mohammad Sabzghabaee, Mojtaba Akbari, Mahdi Hadian, Tooba Momen

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Dendritic Cells and Leishmania Infection: Adding Layers of Complexity to a Complex Disease by Daniel Feijó, Rafael Tibúrcio, Mariana Ampuero, Cláudia Brodskyn, Natalia Tavares

“…Leishmaniasis is a group of neglected diseases whose clinical manifestations depend on factors from the host and the pathogen. …”
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A Novel Sesterterpenoid, Petrosaspongin and γ-Lactone Sesterterpenoids with Leishmanicidal Activity from Okinawan Marine Invertebrates by Takahiro Jomori, Nanami Higa, Shogo Hokama, Trianda Ayuning Tyas, Natsuki Matsuura, Yudai Ueda, Ryo Kimura, Sei Arizono, Nicole Joy de Voogd, Yasuhiro Hayashi, Mina Yasumoto-Hirose, Junichi Tanaka, Kanami Mori-Yasumoto

“…Leishmaniasis is a major public health problem, especially affecting vulnerable populations in tropical and subtropical regions. …”
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Novel Arsenic Nanoparticles Are More Effective and Less Toxic than As (III) to Inhibit Extracellular and Intracellular Proliferation of Leishmania donovani by Sudipta Chakraborty, Kaushik Bhar, Sandip Saha, Rajarshi Chakrabarti, Anjali Pal, Anirban Siddhanta

“…Visceral leishmaniasis, a vector-borne tropical disease that is threatening about 350 million people worldwide, is caused by the protozoan parasite Leishmania donovani. …”
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Comparing the Trends of Vector-Borne Diseases (VBDs) before and after the COVID-19 Pandemic and Their Spatial Distribution in Southern Iran by Zahra Gheibi, Mitra Boroomand, Aboozar Soltani

“…However, the difference between observed and expected values revealed that the consequences of the COVID-19 pandemic had increased the number of leishmaniasis cases. Conclusion. Tropical regions of Iran, including Fars province, are the favorite destinations for travelers. …”
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La Leishmaniosis by Jorge R. Rey

“…Rey, is the Spanish language version of ENY-738: Leishmaniasis. It describes this disease caused by parasitic protozoans transmitted to humans by sandflies. …”
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La Leishmaniosis by Jorge R. Rey

“…Rey, is the Spanish language version of ENY-738: Leishmaniasis. It describes this disease caused by parasitic protozoans transmitted to humans by sandflies. …”
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Calophyllum brasiliense Modulates the Immune Response and Promotes Leishmania amazonensis Intracellular Death by L. Domeneghetti, I. G. Demarchi, J. Z. Caitano, R. B. Pedroso, T. G. V. Silveira, M. V. C. Lonardoni

“…Calophyllum brasiliense is a plant from the Brazilian rain forests and has been used in folk medicine for the treatment of various diseases, including leishmaniasis. This infectious disease depends on the Leishmania sp. and the host immune response. …”
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4-Aminoquinoline as a privileged scaffold for the design of leishmanicidal agents: structure–property relationships and key biological targets by Angel H. Romero, Francisco Delgado

“…Leishmaniasis is one of the most important neglected tropical diseases, with more than two million new cases annually. …”
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Investigating the Existence of Ribosomal Protein L5 Gene in Syrian Strain of Leishmania tropica Genome: Sequencing It and Evaluating Its Immune Response as DNA Vaccine by Mohammad Maarouf, Alyaa A. Abdlwahab

“…Cutaneous leishmaniasis in Syria is caused mainly by Leishmania tropica. …”
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P2Y2 Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1β Secretion by Maria Luiza Thorstenberg, Monique Daiane Andrade Martins, Vanessa Figliuolo, Claudia Lucia Martins Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva

“…Leishmaniasis is a neglected tropical disease caused by an intracellular parasite of the genus Leishmania. …”
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Guanidines Conjugated with Cell-Penetrating Peptides: A New Approach for the Development of Antileishmanial Molecules by João Victor Marcelino de Souza, Natalia C. S. Costa, Maria C. O. Arruda Brasil, Luana Ribeiro dos Anjos, Renata Priscila Barros de Menezes, Eduardo Henrique Zampieri, Jhonatan Santos de Lima, Angela Maria Arenas Velasquez, Luciana Scotti, Marcus Tullius Scotti, Marcia A. S. Graminha, Eduardo R. Pérez Gonzalez, Eduardo Maffud Cilli

“…Leishmaniasis is a neglected tropical disease caused by a protozoan of the genus Leishmania, which has visceral and cutaneous forms. …”
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Human migrations, anthropogenic changes, and insect-borne diseases in Latin America by André B. B. Wilke, Priscilla Farina, Marco Ajelli, Angelo Canale, Filipe Dantas-Torres, Domenico Otranto, Giovanni Benelli

“…Malaria, Chagas disease, yellow fever, and leishmaniasis have historically afflicted the region, while dengue, chikungunya, and Zika have been described and expanded more recently. …”
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Mixed Cutaneous Infection Caused by Leishmania and Dermatophytes: A Rare Coincidence or Immunological Fact by Amresh Kumar Singh, Ankur Kumar, Jayesh Pandey, Vivek Gaur, Pratima Tripathi, Indra Prasad Adhikari

“…Leishmaniasis was first described in 1824, in the Jessore district of Bengal (now Bangladesh) and more prevalent in Bihar, Uttar Pradesh, Jharkhand, and West Bengal. …”
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Cobalamin and Folic Acid Status in Relation to the Etiopathogenesis of Pancytopenia in Adults at a Tertiary Care Centre in North India by M. Premkumar, N. Gupta, T. Singh, T. Velpandian

“…Infectious diseases like tuberculosis, leishmaniasis, and increasingly HIV are important and treatable causes of pancytopenia. …”
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Addressing challenges in vector control: a review of current strategies and the imperative for novel tools in India’s combat against vector-borne diseases by Kuldeep Singh, Amit Sharma, Manju Rahi, Sanjeev Kumar Gupta, Gaurav Kumar, Rajendra Baharia, Sam Joy

“…Malaria, chikungunya, dengue, visceral leishmaniasis, lymphatic filariasis and Japanese encephalitis are among the public health concerns for India. …”
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Performance evaluation of nine reference centers and comparison of DNA extraction protocols for effective surveillance of Leishmania-infected Phlebotomine sand flies: Basis for tec... by Jorian Prudhomme, Aymeric Delabarre, Bulent Alten, Umut Berberoglu, Eduardo Berriatua, Gioia Bongiorno, José Manuel Cristovao, Maya Davidovich-Cohen, Trentina Di Muccio, Ozge Erisoz Kasap, Eleonora Fiorentino, Oscar D Kirstein, Edwin Kniha, Carla Maia, Mesut Mungan, Clara Muñoz-Hernández, Muhammed Nalçaci, Gizem Oguz Kaskan, Yusuf Ozbel, Seray Ozensoy Toz, Ricardo Parreira, Katharina Platzgummer, Ceylan Polat, José Risueño, Liora Studentsky, Gamze Varol, Julia Walochnik, Kardelen Yetişmiş, Florence Robert-Gangneux

“…<h4>Background</h4>Leishmaniasis, caused by Leishmania protozoan parasites transmitted by Phlebotomine sand flies, is a significant public health concern in the Mediterranean basin. …”
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