A Novel Multiplex LAMP Assay for the Rapid and Accurate Diagnosis of Visceral Leishmaniasis Caused by Leishmania infantum from Iran by Sahar Samsami, Sahar Namavari, Saeed Ataei, Abdolmajid Ghasemian, Ava Yazdanpanah, Neda Sepahi, Gholamreza Hatam, Hossein Faramarzi, Hadi Mirzaei, Razie Ranjbar, Ali Ghanbariasad

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Evaluation of Regulatory Immune Response in Skin Lesions of Patients Affected by Nonulcerated or Atypical Cutaneous Leishmaniasis in Honduras, Central America by Gabriela Venicia Araujo Flores, Carmen Maria Sandoval Pacheco, Thaise Yumie Tomokane, Wilfredo Sosa Ochoa, Concepción Zúniga Valeriano, Claudia Maria Castro Gomes, Carlos Eduardo Pereira Corbett, Marcia Dalastra Laurenti

“…In Honduras, Leishmania (L.) infantum chagasi causes both visceral leishmaniasis (LV) and nonulcerated or atypical cutaneous leishmaniasis (NUCL). …”
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Identification of CβS and ODC antimony resistance markers in anthroponotic cutaneous leishmaniasis field isolates by gene expression profiling by Farzaneh Zarrinkar, Iraj Sharifi, Razieh Tavakoli Oliaee, Ali Afgar, Elaheh Molaakbari, Mehdi Bamorovat, Zahra Babaei, Ebrahim Eskandari, Ehsan Salarkia, Marzieh Asadi

“…Twenty-six patients were randomly selected from widely known foci of anthroponotic cutaneous leishmaniasis in southeastern Iran. Written informed consent of the patients was obtained. …”
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Single-nucleotide polymorphisms in genes associated with the vitamin D pathway related to clinical and therapeutic outcomes of American tegumentary leishmaniasis by Iara Barreto Neves Oliveira, Ramon Vieira Nunes, Vanessa Rafaela Milhomem Cruz Leite, Camila Freire Araújo, Murilo Barros Silveira, Sebastião Alves Pinto, Lorena Andrade Lamounier, Clayton Luiz Borges, Edésio Martins, Iane de Oliveira Pires Porto, Rodrigo Saar Gomes, Fátima Ribeiro-Dias

“…The aim of this study was to evaluate single-nucleotide polymorphisms (SNPs) in the components of the vitamin D pathway and associated cytokine genes that could be related to resistance or susceptibility to American tegumentary leishmaniasis (ATL).MethodsThe expressions of IFNG, IL15, IL32, CYP27B1, VDR, and other pro-inflammatory cytokines TNF, IL6, and IL17 genes were evaluated using real-time polymerase chain reaction (qPCR) in lesions of patients with localized cutaneous leishmaniasis (LCL) or mucosal leishmaniasis (ML). …”
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Introducing Single Dose Liposomal Amphotericin B for the Treatment of Visceral Leishmaniasis in Rural Bangladesh: Feasibility and Acceptance to Patients and Health Staff by Eva-Maria Maintz, Mahbub Hassan, M. Mamun Huda, Debashis Ghosh, Md. Shakhawat Hossain, Abdul Alim, Axel Kroeger, Byron Arana, Dinesh Mondal

“…For the treatment of visceral leishmaniasis in Bangladesh, single dose liposomal amphotericin B (ambisome) is supposed to be the safest and most effective treatment. …”
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Recombinase-based amplification coupled with lateral flow chromatography for the specific and sensitive detection and identification of Leishmania major in cutaneous leishmaniasis patients by Insaf Bel Hadj Ali, Yusr Saadi-Ben Aoun, Imen Khammeri, Hejer Souguir, Emna Harigua-Souiai, Hamed Chouaieb, Ahmed S. Chakroun, Meryem Lemrani, Aicha Kallel, Kalthoum Kallel, Nabil Haddad, Oussaima El Dbouni, Rhea N. Coler, Rhea N. Coler, Rhea N. Coler, Steven G. Reed, Akila Fathallah-Mili, Akila Fathallah-Mili, Ikram Guizani

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A Case of Visceral Leishmaniasis in a 4-Year-Old Child Living in Nonendemic Area Located in Suburbs of Dakar, Senegal by Magatte Ndiaye, Dienaba Fafa Cissé, Aicha Djigal, Aminata Sow, Souléye Lélo, Fatoumata Ly, Isaac A. Manga, Mame Ami Diouf, Doudou Sow, Oumar Gaye, Boubacar Camara, Babacar Faye

“…Visceral leishmaniasis (VL) is an infectious disease caused by protozoa of the genus Leishmania. …”
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Identification of a New Pentafluorosulfanyl-Substituted Chalcone with Activity Against Hepatoma and Human Parasites by Alessandra Viperino, Michael Höpfner, Nicole Edel, Ibrahim S. Al Nasr, Waleed S. Koko, Tariq A. Khan, Imen Ben Abdelmalek, Rainer Schobert, Bernhard Biersack, Bianca Nitzsche

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Improved Performance of ELISA and Immunochromatographic Tests Using a New Chimeric A2-Based Protein for Human Visceral Leishmaniasis Diagnosis by Maria Marta Figueiredo, Anna R. R. dos Santos, Lara C. Godoi, Natália S. de Castro, Bruno C. de Andrade, Sarah A. R. Sergio, Selma M. B. Jerônimo, Edward J. de Oliveira, Ruth T. Valencia-Portillo, Lucilândia M. Bezerra, Hiro Goto, Maria C. A. Sanchez, Caroline Junqueira, Santuza M. R. Teixeira, Flávio G. da Fonseca, Ricardo T. Gazzinelli, Ana Paula Fernandes

“…Summary. Human visceral leishmaniasis (VL) is a major public health problem worldwide, leading to significant mortality rates if not properly treated and controlled. …”
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Updates on Prevalence and Trend Status of Visceral Leishmaniasis at Two Health Facilities in Amhara Regional State, Northwest Ethiopia: A Retrospective Study by Mulat Yimer, Endalkachew Nibret, Gizachew Yismaw

“…Of the 2,703 visceral leishmaniasis suspected cases diagnosed with the rK39 test, 877 (32.4%) were confirmed (positive) cases. …”
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Genome-wide association study analysis of single nucleotide variants in L. infantum associated with IL-6 inflammatory response in visceral leishmaniasis by Amanda Miranda da Silva, Kátia Silene Sousa Carvalho, Caio Andrey Bezerra Januário, Raquel Gomes de Sena Carneiro Caldas, Bianka Lopes da Silva Paulino, Débora Cavalcante Braz, Dorcas Lamounier Costa, Gabriel da Luz Wallau, Wilson Jose da Silva Junior, Carlos Henrique Nery Costa

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Prevalence of asymptomatic Leishmania donovani infection and associated factors in Ethiopia: a systematic review and meta-analysis by Habtamu Belay, Adugna Abera, Esayas Aklilu, Tesfahun Bishaw, Ayinalem Alemu, Geremew Tasew, Berhanu Erko

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Targeting Cutaneous Leishmaniasis with Thiadiazine Thione Derivatives: An In Vivo Study of Its Anti-Inflammatory, Anti-Pyretic, Anti-Nociceptive, and Anti-Sedative Properties by Sarah Sarwar, Nadia Sarwar, Haleema Ali, Rafiullah, Rasool Khan, Ajaz Ahmad, Amin Ullah, Ho Soonmin, Nazif Ullah

“…The available treatments against leishmaniasis are inadequate, as they are associated with high cost, toxicity, and increased resistance. …”
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Emergence of coinfection with visceral Leishmania infantum in COVID-19 patients: a case‒control field study in an endemic area of visceral leishmaniasis in Iran by Selva Aminizadeh, Behnam Mohammadi-Ghalehbin, Mehdi Mohebali, Homa Hajjaran, Zabih Zarei, Zahra Heidari, Behnaz Akhondi, Zahra Alizadeh, Jafar Aghaei

“…The present study aimed to determine the frequency of L. infantum infection and its role in disease and mortality among symptomatic COVID-19 patients in comparison with the non-COVID-19 control group in the endemic area of visceral leishmaniasis (VL) in Iran. Methods A total of 250 blood samples from hospitalized COVID-19 patients and 231 blood samples from non-COVID-19 patients as a control group were collected in Mashkin Shahr city, Iran from October 2020 to May 2021, and anti-Leishmania infantum antibodies were detected via direct agglutination test (DAT). …”
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Diagnostic Performance of Three rK39 Rapid Diagnostic Tests and Two Direct Agglutination Tests for the Diagnosis of Visceral Leishmaniasis in Southern Iran by Zahra Rezaei, Bahman Pourabbas, Vera Kühne, Parham Pourabbas, Philippe Büscher

“…To evaluate the diagnostic performance of five alternative serodiagnostic tests, serum samples from 100 confirmed visceral leishmaniasis (VL) patients, 197 healthy endemic individuals, and 58 non-VL patients living in southern Iran were compared. …”
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Performance of Culture Using a Semi-Automatic Needle as a Novel Tool for Collecting Lymph Node Samples for the Diagnosis of Canine Visceral Leishmaniasis by Artur Augusto Velho Mendes Júnior, Fabiano Borges Figueiredo, Luiz Cláudio Ferreira, Lucas Keidel, Renato Orsini Ornellas, Adilson Benedito Almeida, Fernanda Nunes Santos, Luciana de Freitas Campos Miranda, Andreza Pain Marcelino, Sandro Antonio Pereira, Rodrigo Caldas Menezes

Subjects: “…canine visceral leishmaniasis…”
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A comprehensive review of biological and genetic control approaches for leishmaniasis vector sand flies; emphasis towards promoting tools for integrated vector management. by Yasoda Kumari, Nayana Gunathilaka, Deepika Amarasinghe

“…<h4>Background</h4>Leishmaniasis is a health problem in many regions with poor health and poor life resources. …”
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Effect of environmental conditions and preventive behaviors on cutaneous leishmaniasis from the earthquake that hit cities in Western Iran in 2021: A cross-sectional study by Fakhreddin CHABOKSAVAR, Arash ZIAPOUR, Mozhgan IRANDOST, Behzad MAHAKI, Francesco CHIRICO, Murat YILDIRIM, Gabriella NUCERA, Lukasz SZARPAK, Nicola BRAGAZZI, Anvar ASADI

“…Introduction: To investigate the role of environmental conditions, knowledge, attitudes, and control measures of preventive behaviors in cutaneous leishmaniasis (CL) based on the BASNEF model in patients who were referred to the health care centers of cities hit by earthquakes, including Sarpol-Zahab and Qasr-Shirin located in Kermanshah province, Western Iran, in 2021. …”
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Protocol for a prospective observational cohort study of cutaneous leishmaniasis in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations] by Fewzia Shikur Mohammed, Amel Beshir Mohammed, Shimelis Doni Nigusse, Feleke Tilahun Zewdu, Abebaw Yeshambel Alemu, Teklu Cherkose, Kidist Bobosha, Eshetu Molla, Iris Mosweu, Vanessa Yardley, Saba Maria Lambert, Mirgissa Kaba, Endalamaw Gadisa, Yohannes Hailemichael, Catherine Pitt, Elizabeth Allen, Stephen L. Walker, Michael Marks

Subjects: “…Cutaneous leishmaniasis…”
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Entomological Investigations, Seasonal Fluctuations and Impact of Bioclimate Factors of Phlebotomines Sand Flies (Diptera: Psychodidae) of an Emerging Focus of Cutaneous Leishmaniasis in Aichoun, Central Morocco by Fatima Zahra Talbi, Abdelhakim El Ouali Lalami, Mouhcine Fadil, Mohamed Najy, Hassan Ech-Chafay, Mohamed Lachhab, Said Lotfi, Nordine Nouayti, Khadija Lahouiti, Chafika Faraj, Abdellatif Janati Idrissi

“…Leishmaniasis diseases are endemic in Morocco. An entomological survey was conducted in Aichoun locality for 1 year from September 2013 to August 2014. …”
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