Cardiac manifestations of Fabry disease in G3Stg/GlaKO and GlaKO mouse models-Translation to Fabry disease patients. by Abirami Kugadas, Pietro Artoni, Wanida Ruangsiriluk, Meng Zhao, Natalia Boukharov, Rizwana Islam, Dmitri Volfson, Katayoun Derakhchan

“…Loss of α-Gal activity leads to progressive lysosomal accumulation of α-Gal substrate, predominately globotriaosylceramide (Gb3) and its deacylated derivative globotriaosylsphingosine (lyso-Gb3). …”
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Regulation of human papillomavirus E6 oncoprotein function via a novel ubiquitin ligase FBXO4 by Arushi Vats, Luca Braga, Nezka Kavcic, Paola Massimi, Edoardo Schneider, Mauro Giacca, Laimonis A. Laimins, Lawrence Banks

“…Upon validation of the interaction of 18E6 with these ubiquitin ligases in cervical cancer-derived cell lines, we found that the knockdown of ubiquitin ligase F-box protein 4 (FBXO4), together with E6AP knockdown, leads to a dramatic increase in the levels of endogenous HPV-18E6 oncoprotein. …”
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The Model of Disengagement of Talent with Meta-synthesis Method by Ali Asghar Mobasheri, Ali Nasr Isfahani, Hadi Teimouri

“…Thematic analysis was employed to analyze and synthesize the data, ultimately leading to the final results. Results After selecting the appropriate sources, the text of each was meticulously reviewed, and primary codes were extracted. …”
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A Community-Based Intervention for Mental Health and Wellbeing in Pregnancy and Postpartum: One Healthy Start Site’s Story by Sampson M, Xu W, York FN, Roberson J

“…McClain Sampson,1 Wen Xu,2 Felicia N York,3 Jerry Roberson4 1Graduate College of Social Work, University of Houston, Houston, TX, USA; 2Department of Innovative Social Work, Faculty of Health and Wellbeing, City University of Macau, Macao, SAR, People’s Republic of China; 3Texas A&M University, College Station, TX, USA; 4United Associates, Dallas, TX, USACorrespondence: McClain Sampson, Graduate College of Social Work, University of Houston, Houston, TX, USA, Email mmsampson@uh.eduPurpose: Perinatal mood and anxiety disorders (PMADs) are the leading cause for maternal morbidity and are associated with underlying causes of pregnancy-related death. …”
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End-to-End Stroke Imaging Analysis Using Effective Connectivity and Interpretable Artificial Intelligence by Wojciech Ciezobka, Joan Falco-Roget, Cemal Koba, Alessandro Crimi

“…Stroke is one of the leading causes of mortality and morbidity worldwide, and it demands precise diagnostic tools for timely intervention and improved patient outcomes. …”
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Designing a Conceptual model for Evaluating the Performance of Software Developers in Fintech Organizations by Hassan Javadi, Fereshteh Amin

“…Many fintech organizations consistently face challenges in their relationships with software developers, leading to a high turnover rate. This turnover not only results in the loss and transfer of valuable knowledge and experience outside the organization, thereby weakening its competitive position, but also causes stakeholder dissatisfaction and a significant waste of financial and credit resources. …”
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Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

“…FuRong Laboratory, Changsha, Hunan, 410078, People’s Republic of China, Email ghzhang@hunnu.edu.cn Jian Wang, The Institute of Reproduction and Stem Cell Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410006, People’s Republic of China, Email 205106@csu.edu.cnBackground: Ferroptosis is a form of programmed cell death triggered by iron-dependent lipid peroxidation, characterized by iron accumulation and elevated reactive oxygen species (ROS), leading to cell membrane damage. It is associated with a variety of diseases. …”
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Translation and Validation of the Edinburgh Postnatal Depression Scale for Eritrea: A Screening Tool for Postpartum Depression in Primary Health Care Facilities by Gebregziabher NK, Netsereab TB, Alazar FA, Fessaha YG, Sium AH, Ghebrehiwet NK

“…Healthcare providers can now use this culturally and linguistically appropriate tool to screen for postpartum depression, leading to early detection and intervention. Improving screening can significantly enhance new mothers’ mental health and overall well-being, supporting healthier families and communities.Keywords: EPDS, postpartum depression, Eritrea, validation, mental health, Tigrinya…”
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Spinal pain prevalence and associated determinants: A population‐based study using the National Survey for Wales by David C. Byfield, Benjamin S. Stacey, Hywel T. Evans, Ian W. Farr, Leon Yandle, Lora Roberts, Teresa Filipponi, Damian M. Bailey

“…Abstract Spinal pain (SP) remains the leading cause of disability worldwide. The present study aimed to establish a current prevalence of SP and associated determinants in Wales by retrospectively analyzing data from the National Survey for Wales Dataset (NSWD). …”
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Evaluation of mineral and near-infrared forecasting of wheat yield varieties using spectrophotometric techniques by H.A. Pardhe, N. Krishnaveni, B.K. Chekraverthy, S. Patel, S. Naveen, V. Rashmi, P.C. Govinden

“…Inadequate dietary iron intake leads to iron deficiency anemia, affecting nearly 1.6 billion people, especially pregnant women and preschool children. …”
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“I believe it when there is an expert next to me:” a qualitative analysis on the perceptions and experiences of pregnant women to self-monitor blood pressure in Lombok, Indonesia... by Tigest Tamrat, Yuni Dwi Setiyawati, Maria Barreix, Nya’Jeumpa Madani, Antoine Geissbühler, Anuraj H. Shankar, Ozge Tuncalp

“…Abstract Background Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal deaths and require close monitoring of blood pressure (BP) to mitigate potential adverse effects. …”
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Application of artificial intelligence in the health management of chronic disease: bibliometric analysis by Mingxia Pan, Mingxia Pan, Rong Li, Junfan Wei, Huan Peng, Ziping Hu, Yuanfang Xiong, Na Li, Yuqin Guo, Weisheng Gu, Hanjiao Liu, Hanjiao Liu

“…The United States and the Journal of Medical Internet Research were the leading contributors in this field. Our analysis of the 341 publications revealed four primary research clusters: diagnosis, care, telemedicine, and technology. …”
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Photosynthetic Induction Characteristics in Saplings of Four Sun-Demanding Trees and Shrubs by Qiuping Liu, Wei Jin, Liying Huang, Danfeng Wang, Kedong Xu, Yunmin Wei

“…Light serves as the unique driving force of photosynthesis in plants, yet its intensity varies over time and space, leading to corresponding changes in the photosynthetic rate. …”
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April 15th war and hemodialysis patients in Sudan: a cross-sectional study by Malaz Hassan Dafaalla Idrees, Moez Mohammed Ibrahim Bashir, Balqees Abdeen Ahmed Mohamed, Amal Essam Ali Ahmed, Hamid Mohieldin Mohamed Abdalla, Kamil Mirghani Ali Shaaban

“…Abstract Background On April 15th, 2023, intense clashes involving heavy weapons and airstrikes occurred between the Sudanese Armed Forces (SAF) and the paramilitary Rapid Support Forces (RSF) in Khartoum, the capital of Sudan, leading to the displacement of almost 8.1 million people. …”
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Water, Sanitation and Hygiene in a Conflict Area: A Cross-Sectional Study in South Kordofan, Sudan by Rofida Asmally, Abdelmalik A. Imam, Abdullatif Eissa, Abubakr Saeed, Ahmed Mohamed, Eahaa Abdalla, Mariam Alazraa M. Esmaeel, Mariam Elbashir, Mohamed H. Elbadawi, Mohammed Omer, Raghad Eltayeb, Ranya Mohammed, Tibyan Abdalhamed, Tina Merghani

“…Moreover, these conflicts led to disruption of the economical status leading to the absence of proper water purification infrastructure.…”
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Whole-genome sequencing and metagenomics reveal diversity and prevalence of Listeria spp. from soil in the Nantahala National Forest by Jia Wang, Claire N. Schamp, Lauren K. Hudson, Harleen K. Chaggar, Daniel W. Bryan, Katie N. Garman, Mark Radosevich, Thomas G. Denes

“…Moreover, using a metagenomic approach provides a detailed understanding of the soil microbial ecosystems, leading to more effective monitoring and control of foodborne pathogens. …”
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Growth of microbes in competitive lifestyles promotes increased ARGs in soil microbiota: insights based on genetic traits by Zishu Liu, Xiangwu Yao, Chengyi Chen, Yuxiang Zhao, Chifei Dong, Lingtao Sun, Junxian Zhao, Baofeng Zhang, Zhendi Yu, Dongqing Cheng, Lizhong Zhu, Baolan Hu

“…They possess greater substrate utilization capacity and carry more ARGs, due to this they were faster growing and leading to a greater increase in the abundance of ARGs. …”
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Accurate phenotype-to-genotype mapping of high-diversity yeast libraries by heat-shock-electroporation (HEEL) by Marcus Wäneskog, Emma Elise Hoch-Schneider, Shilpa Garg, Christian Kronborg Cantalapiedra, Elena Schäfer, Michael Krogh Jensen, Emil Damgaard Jensen

“…The HEEL methodology presented here aims to address this issue by minimizing the problem of multi-plasmid uptake during high-throughput yeast DNA transformations, which leads to the creation of heterogeneous cellular genotypes. …”
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Early Electroacupuncture Extends the rtPA Time Window to 6 h in a Male Rat Model of Embolic Stroke via the ERK1/2-MMP9 Pathway by Xin-chang Zhang, Ya-hui Gu, Wen-tao Xu, Yang-yang Song, Ao Zhang, Zhi-hui Zhang, Si-yuan Jiang, Si-qi Chang, Guang-xia Ni

“…When administered at time points greater than 4.5 h after stroke onset, rtPA disrupts the blood-brain barrier (BBB), which leads to serious brain edema and hemorrhagic transformation. …”
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Biomimetic polydopamine loaded with janus kinase inhibitor for synergistic vitiligo therapy via hydrogel microneedles by Chunying Li, Wenwen Wang, Junyi Shao, Sen Zhou, Xiaolin Ji, Youxia Xi, Qiuyang Xu, Yuhan Huang, Jingle Wang, Yilin Wan, Zhiming Li

“…Under oxidative stress, the apoptotic melanocytes expose self-antigens and release high mobility group box 1 (HMGB1), triggering autoimmune activation and recruiting CD8+ T cells. This process further leads to the destruction of melanocytes, resulting in the lack of melanin granules. …”
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