Sex-based differences in the long-term fate of hippocampal neurons born after a traumatic brain injury by Hannah C. Downing, Hannah C. Downing, Ashley B. Glover, Jessica E. Gebhardt, Jessica E. Gebhardt, Katherine L. Thompson, Kathryn E. Saatman, Kathryn E. Saatman, Kathryn E. Saatman

“…IntroductionModerate-to-severe traumatic brain injury (TBI) results in an early loss of immature hippocampal granule cells and the activation of typically quiescent neural stem cells (NSCs) in the dentate gyrus. Activation of NSCs leads to a robust increase in proliferation and generation of neural progenitor cells (NPCs), supporting restoration of the immature neuron population of over a period of 1–2 weeks. …”
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Circular RNA circBNC2 inhibits tumorigenesis by modulating ferroptosis and acts as a nanotherapeutic target in prostate cancer by Xiang Pan, Kailai Chen, Wei Gao, Meiqi Xu, Fanlong Meng, Mengyuan Wu, Zi Qi Wang, Yun Qi Li, Wanhai Xu, Manjie Zhang, Yakun Luo

“…Abstract Background Metastasis is a leading cause of cancer-related death in castration-resistant prostate cancer (CRPC) patients. …”
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Advancements in Hyaluronic Acid Effect in Alveolar Ridge Preservation: A Narrative Review by Paul Andrei Nistor, Andreea Cândea, Iulia Cristina Micu, Andrada Soancă, Carmen Silvia Caloian, Alina Bârdea, Alexandra Roman

“…<b>Background/Objectives</b>: Tooth extraction induces significant alveolar ridge dimensional changes and soft tissue modifications, often leading to challenges in implant placement or conventional prosthetic rehabilitation. …”
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uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease by Yu Shen, Kaiyan Jiang, Dandan Tan, Min Zhu, Yusen Qiu, Pencheng Huang, Wenquan Zou, Jianwen Deng, Zhaoxia Wang, Ying Xiong, Daojun Hong

“…Results Single-cell sequencing revealed a significant reduction in the expression of NFKBIA, encoding NF-κB inhibitor alpha (IkBa), which facilitates the nuclear translocation of p65, a key NF-κB component. uN2CpolyG directly interacted with and sequestered p65 in nuclear inclusions, leading to reduced phosphorylated p65 (p-p65) levels. …”
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Oxidative Stress, Antioxidant Capacity, and Inflammatory Markers in Patients with Idiopathic Complete Heart Block by Shobhit Shah, Monika Bhandari, Pravesh Vishwakarma, Wahid Ali, Mohammad Kaleem Ahmad, Abhishek Singh, Ayush Shukla, Akhil Kumar Sharma, Gaurav Chaudhary, Akshyaya Pradhan, Sharad Chandra, Rishi Sethi, S. K. Dwivedi

“…Total antioxidant capacity levels(TOAC) (P = 0.025), GSH (P = 0.027), CAT (P = 0.003), and SOD (P = 0.891) were considerably lower in patients during a CHB compared to the healthy control group, indicating that an increase in oxidative free radicals leads to endothelial dysfunction. High significant increases in MDA (P ≤ 0.001) were indicative of increased reactive oxygen species-mediated tissue damage. …”
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Changing trends in the global burden of polycystic ovarian syndrome-related infertility over the past 30 years: retrospective data analysis of the global burden of disease study 20... by Ming Huo, Yixiang Wang, Xianbin Yuan, Yue Yuan, Xuehong Zhang

“…Abstract Objectives Polycystic ovary syndrome (PCOS) represents a significant and persistent metabolic disorder, emerging as a leading factor contributing to infertility. Despite its profound impact, there remains an inadequate understanding of the global burden of PCOS-related infertility across diverse regions and countries. …”
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Crystal structures of zinc(II) coordination complexes with isoquinoline N-oxide by Erin N. Groneck, Nathan Peek, Will E. Lynch, Clifford W. Padgett

“…However, starting with zinc(II) perchlorate or nitrate leads to the formation of complex ions with the compositions [Zn(iQNO)6](X)2 for X = ClO4− (IV), and [Zn(iQNO)(H2O)5](iQNO)2X2 for X = NO3− (V). …”
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Hydrogen-oxygen mixture inhalation as an adjunctive treatment to home-based exercise in older patients with knee osteoarthritis: an open-label, blinded-endpoint, randomized control... by Chenhui Wang, Mengwei Yan, Yuru Li, Lei Han, Hongqian Wang, Shufeng Jia, Xingchen Liu, Yang Liu, Fan Wu, Baoguo Wang

“…ObjectiveKnee osteoarthritis (KOA) is a degenerative joint condition, leading to disability and diminished quality of life. …”
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The miR-146a SNP Rs2910164 and miR-155 SNP rs767649 Are Risk Factors for Non-Small Cell Lung Cancer in the Iranian Population by Neda K. Dezfuli, Ian M. Adcock, Shamila D. Alipoor, Sharareh Seyfi, Babak Salimi, Maryam Mafi Golchin, Neda Dalil Roofchayee, Mohammad Varhram, Esmaeil Mortaz

“…Lung cancer is one of the leading causes of death worldwide. MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and may act as both tumor suppressors and as oncogenes. …”
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Plasma S100β is a predictor for pathology and cognitive decline in Alzheimer’s disease by Geetika Nehra, Bryan J. Maloney, Rebecca R. Smith, Wijitra Chumboatong, Erin L. Abner, Peter T. Nelson, Björn Bauer, Anika M. S. Hartz

“…Abstract Background Blood–brain barrier dysfunction is one characteristic of Alzheimer’s disease (AD) and is recognized as both a cause and consequence of the pathological cascade leading to cognitive decline. The goal of this study was to assess markers for barrier dysfunction in postmortem tissue samples from research participants who were either cognitively normal individuals (CNI) or diagnosed with AD at the time of autopsy and determine to what extent these markers are associated with AD neuropathologic changes (ADNC) and cognitive impairment. …”
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Blastic plasmacytoid dendritic cell neoplasm: a Swiss case series of a very rare disease and a structured review of the literature by Ramona Meier-Lienhard, Cosima Suter, Thomas Pabst, Felicitas Hitz, Jakob R. Passweg, Olivier Spertini, Nathan Cantoni, Daniel Betticher, Lucas Simeon, Michael Medinger, Stefanie Hayoz, Adrian Schmidt

“…METHODS: We collected data from BPDCN patients from leading Swiss haemato-oncology centres from 2005 to 2022. …”
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The Policy and Governance Observatory as a Facilitator of Smart and Evidence-based Governance by Atiye Yousefi, Mahdi Abdolhamid

“…The result of these actions leads to the publication of databases and policy and policy research reports, which, in addition to providing comprehensive insight to government officials and improving the quality of their future decisions, also convey extensive information to citizens that it has a significant effect in informing the society about the functioning of the system and promoting social capital. …”
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Exploring the barriers to cervical screening and perspectives on new self-sampling methods amongst under-served groups by Stephanie Gillibrand, Helen Gibson, Kelly Howells, Sean Urwin, Jennifer C. Davies, Emma J. Crosbie, Caroline Sanders

“…Self-sampling methods (vaginal swab and urine collection) were positively received by participants, and may address some existing barriers through the proponents of enhanced choice – between method and location (which also dovetailed with convenience) leading to greater empowerment. The removal of the speculum and lack of invasive examination by a healthcare professional was also positively received. …”
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Estimating the Cost-Effectiveness of Tumor Treating Fields (TTFields) Therapy with an Immune Checkpoint Inhibitor or Docetaxel in Metastatic Non-Small Cell Lung Cancer by Furnback W, Wu E, Koh CYC, Nino de Rivera Guzman JF, Kruhl C, Kotecha R, Wang BC

“…Wesley Furnback,1 Elizabeth Wu,1 Cloe Ying Chee Koh,2 Jorge Fernando Nino de Rivera Guzman,2 Christian Kruhl,3 Rupesh Kotecha,4 Bruce CM Wang3 1Real Chemistry, New York, NY, USA; 2Novocure, Inc, Portsmouth, NH, USA; 3Novocure GmbH, Root, Switzerland; 4Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, Miami, FL, USACorrespondence: Bruce CM Wang, Novocure GmbH, Neuhofstrasse 21, Baar, 6340, Switzerland, Email bcwang@novocure.comPurpose: Lung cancer remains a leading cause of cancer-related mortality. Tumor Treating Fields (TTFields) therapy extended survival in patients with metastatic non-small cell lung cancer (NSCLC) on or after platinum-based therapy. …”
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Entre espaces domestiques et « espaces domestiqués » : « L’autonomisation intime » des étudiantes en Turquie by Tuğba Gökduman

“…The article concludes that the rules of these spaces do not refrain women to search for ways leading to sexual emancipation. It also underlines that these women construct their individuality and their access to sexuality at the crossroads of different sexual norms and moral expectations. …”
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Double-Blind Clinical Trial of Arginine Supplementation in the Treatment of Adult Patients with Sickle Cell Anaemia by Renata M. N. Eleutério, Francisco O. Nascimento, Tamara G. Araújo, Marilena F. Castro, Tarcísio P. Almeida Filho, Pedro A. Maia Filho, José Eleutério, Darcielle B. D. Elias, Romélia P. G. Lemes

“…Because arginine is a substrate for NO formation, this decrease leads to reduced NO (vasodilator) synthesis. SCA treatment uses hydroxyurea (HU) to maintain high foetal haemoglobin (HbF) levels and reduces HbS to avoid haemolytic episodes. …”
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No Need to Know: Toward Astrophysics-free Gravitational-wave Cosmology by Amanda M. Farah, Thomas A. Callister, Jose María Ezquiaga, Michael Zevin, Daniel E. Holz

“…However, the use of an inaccurate representation leads to biases in the cosmological inference, an acute problem given the current uncertainties in true source population. …”
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Rehabilitation using virtual gaming for Hospital and hOMe-Based training for the Upper limb post Stroke (RHOMBUS II): protocol of a feasibility randomised controlled trial by Cherry Kilbride, Tom Butcher, Meriel Norris, Nana Anokye, Alyson Warland, Karen Baker, Dimitrios A Athanasiou, Guillem Singla-Buxarrais, Jennifer Ryan, Francesca Gowing, Carole Pound, Victoria Stewart, Basaam Aweid, Arul Samiyappan

“…Introduction Upper limb (UL) rehabilitation is most effective early after stroke, with higher doses leading to improved outcomes. For the stroke survivor, the repetition may be monotonous. …”
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Effect of Channel Orientation and Rib Pitch-to-Height Ratio on Pressure Drop in a Rotating Square Channel with Ribs on Two Opposite Surfaces by Prabhu S. V., Arora Neelabh, Vedula R. P.

“…The test section in which the ribs are placed on the leading and trailing surfaces is considered as the base case (<math alttext="$ext{orientation angle} = 0^{circ}$"> <mtext>orientation angle</mtext><mo>=</mo><msup> <mn>0</mn> <mo>&compfn;</mo> </msup> </math>, Coriolis force vector normal to the ribbed surfaces). …”
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Prevalence and Determinants of Diarrheal Diseases among Under-Five Children in Horo Guduru Wollega Zone, Oromia Region, Western Ethiopia: A Community-Based Cross-Sectional Study by Kefalew Alemayehu, Lemessa Oljira, Melake Demena, Abdi Birhanu, Dasselegn Workineh

“…Diarrheal diseases are the leading cause of preventable death, especially among under-five children in developing countries, including Ethiopia. …”
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