Corticostriatal maldevelopment in the R6/2 mouse model of juvenile Huntington's disease by Carlos Cepeda, Sandra M. Holley, Joshua Barry, Katerina D. Oikonomou, Vannah-Wila Yazon, Allison Peng, Deneen Argueta, Michael S. Levine

“…There is a growing consensus that brain development in Huntington's disease (HD) is abnormal, leading to the idea that HD is not only a neurodegenerative but also a neurodevelopmental disorder. …”
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Advancing early detection of organ damage and cardiovascular risk prevention: the Suzhou cardiometabolic health study protocol - exploring the role of oral microbiome and metabolic... by Mengmeng Zhu, Mengmeng Zhu, Yiwen Li, Wenting Wang, Longkun Liu, Wenwu Liu, Jiayu Yu, Qian Xu, Jing Cui, Yanfei Liu, Keji Chen, Yue Liu, Yue Liu

“…BackgroundCardiovascular Disease (CVD) is the leading cause of global mortality, with its incidence rate rising year by year due to the prevalence of metabolic diseases. …”
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Earth–lunar thermal effect on the temperature stability of TianQin telescope and the suppression methods by Wenbo Chang, Yuxiang Wang, Wenhai Tan, Guanhua Wu, Houyuan Chen, Wei Li, Zizheng Li, Fan Zhu, Zhu Li, Xuefeng Zhang, Shanqing Yang

“…Subsequent implementation of vanes within the baffle serves to further suppress the earth and lunar heat flux disturbances, leading to an improved temperature stability of about 0.04 mK/Hz @0.1 mHz and 0.7 μKHz @2 mHz, one order of magnitude below the TianQin total requirement. …”
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Designing a model for fostering organizational resilience based on organizational agility components by Heidar kadivar zinkanloo, gholamabbas shekari, saeed emamgholizadeh

“…Also, the understanding of science guides us to determine the concept of science as a process or method that leads us to a scientific knowledge that can reach the concept of the same science (Paloș et al, 2019). …”
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The relationship between cognitive dissonance, scientific reasoning and systemic thinking with the academic progress of Babol University physics students with the mediating role of... by Akram Kamel Zaherolmahni, Mohammad hassani, Hasan ghalavandi

“…Also, the understanding of science guides us to determine the concept of science as a process or method that leads us to a scientific knowledge that can reach the concept of the same science (Paloș et al, 2019). …”
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Designing an entrepreneurial model in the banking network with a digital technology approach by Afshin Nobakht, majid nasiri, parviz Saeedi

“…Also, the development of banking entrepreneurship with the dimensions of organizational entrepreneurship development, commercial entrepreneurship development, electronic entrepreneurship development, and digital entrepreneurship model development leads to the acceleration of the creation of the banking digital entrepreneurship network. …”
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Designing and Explaining the Competence Model of Knowledge Engineers in Municipalities (Study Case: Tehran Municipality) by Amin Seyyed Nosrati, Zahra Foroutani, Atyieh Bohrani

“…The primary competencies and components of knowledge engineers were identified based on these interviews, leading to the development and explanation of a competence model specifically for knowledge engineers within the Tehran Municipality. …”
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Impact of early arterial-phase multidetector CT in blunt spleen injury: a clinical outcomes-oriented study by Yu-Hao Wang, Yu-Tung Wu, Huan-Wu Chen, Yu-San Tee, Chih-Yuan Fu, Chien-Hung Liao, Chi-Tung Cheng, Chi-Hsun Hsieh

“…NOM failure refers to either NOM-Obs or TAE failure leading to splenectomy. NOM-Obs failure refers to cases initially managed with observation only, but later requiring either TAE or splenectomy. …”
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The potential synergistic effect of combining doxorubicin with vorinostat in urothelial carcinoma therapy by Cheng-Huang Shen, Shou-Chieh Wang, Kah-Min Lee, Hsin-Ting Liu, Szu-Wei Huang, Jin-Yi Wu, Yi-Wen Liu

“…Z-VAD-FMK also completely reduced the protein expression of cleaved caspase 3 and γ-H2AX, suggesting that combining doxorubicin and vorinostat leads to DNA strand breaks and apoptosis. Pre-treatment with Z-IETD-FMK, a specific caspase 8 inhibitor, shows a slight recovery of cell viability in 5637 and BFTC 905 cells following combined treatment. …”
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First-trimester Doppler Ultrasound for Predicting Successful Management of Pregnancy with Recurrent Pregnancy Losses Due to Antiphospholipid Syndrome and Thrombophilia: A Cohort St... by Muhammad Adrianes Bachnas, Uki Retno Budihastuti, Eriana Melinawati, Nutria Widya Purna Anggraini, Robert Ridwan, Lini Astetri, Agung Sari Wijayanti, Atthahira Amalia Hafiizha, Muhammad Denny Gagah Pradana, Aliffudin Nur, Muhammad Alamsyah Azis, Wiryawan Permadi, Luthfi Rahman, Jimmy Yanuar Annas, Daniel Jonathan Mangapul Siagian, Neissya Nastiti Firmanto, Gilang Rizqy Perdana Aries Rohman, Muhammad Ilham Aldika Akbar

“…Background: Recurrent pregnancy loss (RPL) often stems from a hypercoagulable state that exacerbates conditions such as antiphospholipid syndrome (APS) and thrombophilia, leading to early placental issues. Although treatments such as low-molecular-weight heparin (LMWH) and low-dose aspirin (LDA) are used, outcomes vary. …”
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Mechanism of Action of <i>Fusarium oxysporum</i> CCS043 Utilizing Allelochemicals for Rhizosphere Colonization and Enhanced Infection Activity in <i>Rehmannia glutinosa</i> by Feiyue Yuan, Fuxiang Qiu, Jiawei Xie, Yongxi Fan, Bao Zhang, Tingting Zhang, Zhongyi Zhang, Li Gu, Mingjie Li

“…<i>Rehmannia glutinosa</i> is an important medicinal herb; but its long-term cultivation often leads to continuous cropping problems. The underlying cause can be attributed to the accumulation of and alterations in root exudates; which interact with soil-borne pathogens; particularly <i>Fusarium oxysporum</i>; triggering disease outbreaks that severely affect its yield and quality. …”
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Anatomical and Functional Outcomes of Vitrectomy with/without Intravitreal Methotrexate Infusion for Management of Proliferative Vitreoretinopathy Secondary to Rhegmatogenous Retin... by Samir El Baha, Mahmoud Leila, Ahmed Amr, Mohamed M. A. Lolah

“…Methotrexate as an adjuvant therapy blocks essential drivers in the pathogenetic cascade leading to PVR. Intravitreal infusion has the advantage of blocking the pathology in its nascence and obviates the need for repeated intravitreal injections of the drug.…”
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Semen Analysis of Covid-19 Survivors and Uninfected Men: Examining the Motility, Concentration, Vitality, and Morphology Parameters of Spermatozoa by Sri Musta'ina, Eko Budi Siswidiyanto, Pety Narulita, Agustinus, Aucky Hinting, Atika, Zakiyatul Faizah

“…Spermatozoa can be affected by coronavirus disease 2019 (COVID-19) due to a disruption in spermatogenesis, leading to a decline in semen quality. 2. This study compared the semen quality of COVID-19 survivors and those who had not been infected with COVID-19, specifically on the first spermatogenesis cycle following the confirmation of COVID-19 infection. 3. …”
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Genetic predisposition to Behcet's disease mediated by a IL10RA enhancer polymorphism by Handan Tan, Zhenyu Zhong, Xiaojie Feng, Xiang Luo, Qingfeng Cao, Peizeng Yang

“…The protective G-allele of non-coding rs4936415 located inside an enhancer region of IL10RA promoted the enhancer activity and increased the expression of IL10RA.The risk C-allele is able to specifically bind NF-κB1 and, in turn, promotes enhancer activity of IL10RA. This subsequently leads to an increased expression of IL10RA. Low expression of IL-10RA suggests a relative deficiency of NF-κB1 in BD.…”
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Research Progress of Intelligent Evaluation and Virtual Reality Based Training in Upper Limb Rehabilitation afrer Stroke by XIE Qiurong, LIN Wanqi, ZHANG Qi, SHENG Bo, ZHANG Yanxin, HUANG Jia

“…Stroke is the leading cause of disability worldwide, with approximately 85% of poststroke patients experiencing upper extremity dysfunction at first presentation and only 5% to 20% fully recovered at six months post-stroke. …”
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The mediating role of social support in self-management and quality of life in patients with liver cirrhosis by Ying Zhang, LeYao Xiao, Qian Liu, XinYi Zhang, MingDan Li, YaLi Xu, Mei Dai, Fei Zhao, YouShu Shen, Jordan Tovera Salvador, Ping Yang

“…Abstract Patients with liver cirrhosis often experience factors such as malnutrition and lack of exercise, leading to reduced quality of life. Insufficient social support is related to self-management in patients with chronic diseases. …”
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hUC-MSC preserves erectile function by restoring mitochondrial mass of penile smooth muscle cells in a rat model of cavernous nerve injury via SIRT1/PGC-1a/TFAM signaling by Mengbo Yang, Xinda Chen, Ming Zhang, Xiaolin Zhang, Dongdong Xiao, Huiming Xu, Mujun Lu

“…In addition, knockdown of SIRT1 in CCSMCs abolished the protective effects of hUC-MSC on mitochondrial mass and function, while leading to an increase in cellular apoptosis. Conclusions hUC-MSC contribute to the recovery of erectile function in CNI-ED rats by restoring mitochondrial mass and function of CCSMCs through the SIRT1/PGC-1α/TFAM pathway. …”
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RETRACTED: Long non‐coding RNA Sox2OT promotes coronary microembolization‐induced myocardial injury by mediating pyroptosis by Liying Xuan, Danni Fu, Dong Zhen, Dongsong Bai, Lijun Yu, Guohua Gong

“…Silencing of Sox2OT favoured miR‐23b binding to 3′UTR of TLR4 mRNA leading to suppressed TLR4‐mediated NFKB signalling and pyroptosis in myocardial tissues harvested from CME rat models. …”
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Comparative performance of microscopy, rapid diagnostic tests, and multiplex real-time PCR for detection of malaria parasites among pregnant women in northwest Ethiopia by Zemenu Tamir, Abebe Animut, Sisay Dugassa, Araya Gebresilassie, Mahlet Belachew, Adugna Abera, Berhanu Erko

“…Abstract Background Low malaria parasitaemia is a diagnostic challenge in pregnancy, leading to false negative microscopy and rapid diagnostic test (RDT) results. …”
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The potential benefits of radiotherapy in elderly patients with early-stage triple-negative breast cancer by Zheng Xu, Zheng Xu, Chengdong Qin, Binxiao Cao, Binxiao Cao, Pengcheng Ruan, Pengcheng Ruan, Mianhao Zhang, Mianhao Zhang, Guidong Chen, Guidong Chen

“…BackgroundBreast cancer (BC) is the most common cancer in women in the U.S. and a leading cause of cancer-related deaths. The incidence rises with age, especially in women over 70. …”
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