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26221
<i>Salmonella enterica</i> serovar Schwarzengrund: Distribution, Virulence, and Antimicrobial Resistance
Published 2025-01-01“…This serotype has been isolated from poultry, retail meat, and other food products, leading to multiple outbreaks. Alongside the increase in infections, there are growing concerns about the increasing levels of antimicrobial resistance (AMR) among <i>S.…”
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26222
Death trends for 2010 - 2022 for members of a large private medical scheme in South Africa
Published 2024-07-01“…Malignant neoplasms and cardiovascular disease have been and remained the two leading causes of death for Discovery Health Medical Scheme (DHMS) clients between 2012 and 2022. …”
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26223
Multi-modal characterisation of early-stage, subclinical cardiac deterioration in patients with type 2 diabetes
Published 2024-10-01“…Our goal is to quantify T2DM-driven abnormalities in ECG and cardiac imaging biomarkers leading to cardiovascular disease. Methods We quantified ECG and cardiac magnetic resonance imaging biomarkers in two matched cohorts of 1781 UK Biobank participants, with and without T2DM, and no diagnosed cardiovascular disease at the time of assessment. …”
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26224
EGCG improve meat quality, restore lipid metabolism disorder and regulate intestinal flora in high-fat fed broilers
Published 2025-03-01“…The results showed that EGCG increased lightness (L*) 24 h (P < 0.05), and decreased drip loss (P < 0.05) of chicken meat; Enhanced the presence of non-essential and flavor amino acids in muscle tissue and greatly enhanced the antioxidant capacity of broilers, leading to a noteworthy upregulation of antioxidant genes at the genetic level (P < 0.05); Reduced in blood lipids, blood glucose, liver and abdominal fat accumulation in high-fat diet-induced obese chickens (P < 0.05), markedly improved serum and liver biochemical parameters, and histological analysis results also demonstrated that EGCG markedly decreased hepatic lipid accumulation caused by HFD feeding. …”
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26225
Changes in Internet Activities and Influencing Factors for Problematic Internet Use During the COVID-19 Pandemic in Korean Adolescents: Repeated Cross-Sectional Study
Published 2025-02-01“…ConclusionsDuring the COVID-19 pandemic, internet use for academic and commercial purposes, including remote classes and videoconferences, increased rapidly worldwide, leading to a significant rise in overall internet use time. …”
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26226
Standardized Outcomes for Randomized Controlled Trials Targeting Early Interventions in Patients With Moderate-to-Severe Traumatic Brain Injury: Protocol for the Development of a C...
Published 2025-01-01“…In the last 20 years, there has been an increase in clinical trials in neurocritical care, leading mostly to negative results. The evaluation of neurological outcomes, predominantly as primary outcomes, using clinical scales (Glasgow Outcome Scale) has limitations that could explain these results. …”
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26227
Characteristics and Influencing Factors of Soil CH4 and N2O Fluxes in Typical Broad-leaved Forests in the Yangtze River Delta Region, China
Published 2024-12-01“…Litter had a significant impact on CH4 absorption and N2O emissions, with litter remove leading to a 29.9% increase in CH4 influx and a 53.2% increase in N2O efflux. …”
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26228
Mindfulness Intervention for Health Information Avoidance in Older Adults: Mixed Methods Study
Published 2025-01-01“…The complexity of online health information often leads to psychological challenges, such as cyberchondria, exacerbating health information avoidance behaviors. …”
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26229
Unilateral biportal endoscopic decompression combined with percutaneous pedicle screw fixation offers new treatment option for thoracolumbar burst fractures with secondary spinal s...
Published 2025-01-01“…In Type A3 fractures, there is often a displacement of fracture fragments into the spinal canal, leading to secondary spinal stenosis. The traditional approach is posterior open surgery pedicle screws combined with direct visualization for decompression, which requires extensive stripping of paravertebral muscles and resection of more bone, and is more traumatic2, which is not in line with the current development concept of minimally invasive spine. …”
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26230
Kinesiophobia and associated factors among people with musculoskeletal disorders in Ethiopia: a multicenter cross-sectional study
Published 2025-01-01“…Abstract Introduction Kinesiophobia has a major health impact on patients with Musculoskeletal disorders (MSDs) in their functional and physical activities, which leads to poor outcomes, loss of motivation, loss of mobility, and decreased quality of life. …”
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26231
Bi-level data-driven enterprise-wide optimization with mixed-integer nonlinear scheduling problems
Published 2025-03-01“…Among different layers of the operating decisions, planning and scheduling are often treated sequentially, leading to impractical solutions. To tackle this problem, integrated approaches, such as bi-level programming are utilized to optimize these two layers simultaneously. …”
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26232
After neonatal care, what next? A qualitative study of mothers’ post-discharge experiences after premature birth in Kenya
Published 2025-01-01“…Prominent healthcare structural and socio-economic factors in SSA, for example poverty and weak health systems, amplify vulnerabilities for mothers and premature babies; often leading to poor outcomes. Post-discharge mortality rates are high, and readmission is common. …”
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26233
Correlation Analysis of the Entorhinal Cortex-Hippocampus Nerve Fiber Changes and Memory Dysfunction in P301L-Tau Mouse Model and Molecular Mechanism
Published 2023-04-01“…Pearson correlation analysis was used to analyze the correlation between fractional anisotropy (FA) values in different brain regions of the entorhinal cortex-hippocampus and their corresponding learning and memory functions.Results(1) Learning and memory function test: compared with the control group, the learning and memory function of the model group significantly decreased, the escape latency significantly increased, the number of platform crossings and time ratio of target quadrant significantly decreased (<italic>P</italic><0.05). (2) Structure of nerve fibers in the entorhinal cortex and hippocampus: compared with the control group, FA values of the entorhinal cortex and hippocampus in the model group decreased more significantly, MD values of the entorhinal cortex in the model group increased more significantly, while there was no significant difference in the MD values of the hippocampus in the model group (<italic>P</italic>>0.05). (3) Correlation analysis between FA values in the entorhinal cortex-hippocampus and learning and memory function: FA values in the entorhinal cortex and hippocampus were positively correlated with the number of platform crossings (<italic>r</italic>=0.76, <italic>P</italic><0.05; <italic>r</italic>=0.62, <italic>P</italic><0.05). (4) Expression of t-Tau, Ser262 and GSK3β protein in the entorhinal cortex-hippocampus: compared with the control group, the expression of t-Tau, p-Tau (Ser262) and GSK3β protein of entorhinal cortex and hippocamp increased more significantly in the model group (<italic>P</italic><0.05).ConclusionThe Tau protein in the entorhinal cortex-hippocampus of the P301LTau mouse model was hyperphosphorylated, which leads to destruction of the nerve fiber structures in the entorhinal cortex-hippocampus and learning and memory dysfunctions. …”
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26234
In vitro study of size-dependent inhibition of human cytochrome P450 (P450) P450-1A2, P450-2A6, P450-2B6, P450-2C8, P450-2E1, P450-2J2, and P450-3A5 by zinc oxide nanoparticles (Zn...
Published 2025-02-01“…Cytochrome P450 (P450-) isozymes, which play a crucial function in human bio-transforming drugs, can be inhibited by ZnONPs, leading to slower clearance of co-administrated drugs and elevated drug plasma concentrations. …”
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26235
Disruption of zinc homeostasis reverses tigecycline resistance in Klebsiella pneumoniae
Published 2025-02-01“…Specifically, PBT2 increased the concentration of intracellular zinc ions in K. pneumoniae, leading to a suppression of superoxide dismutase activity within the cell and an elevation of reactive oxygen species concentration. …”
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26236
Systematic Review with Network Meta-Analysis: Comparative Efficacy and Safety of Combination Therapy with Angiotensin II Receptor Blockers and Amlodipine in Asian Hypertensive Pati...
Published 2019-01-01“…Hypertension (HTN) is the leading risk factor for cardiovascular mortality globally. …”
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26237
Parametric Study of the Borehole Drilling in Jointed Rock Mass
Published 2021-01-01“…The overlap of the position of the maximum von Mises stress or the maximum displacement with different joint angles or different numbers of joint leads to a reexploration of such positions. The position of the maximum von Mises stress and the maximum displacement o is relatively steady, which locates symmetrically around the borehole. …”
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26238
Sport innovation structure landscape in Switzerland and abroad
Published 2025-01-01“…Successful elite sport policies: An international comparison of the Sports Policy factors Leading to International Sporting Success (SPLISS 2.0) in 15 nations. …”
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26239
Unlocking the Potential of Receptor-Based Approaches in Diabetes Treatment
Published 2025-01-01“…Additionally, patient monitoring, adherence, and self-management will be greatly aided by the integration of digital health technology, telemedicine, and artificial intelligence (AI), thus leading to better treatment outcomes and patient quality of life. …”
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26240
The Association of Pension Income with the Incidence of Type I Obesity among Retired Israelis
Published 2019-01-01“…Previous studies have identified obesity and overweight as the fourth leading risk factor for global mortality. The objective of the current study is to investigate gender differences and the impact of wealth and income from pensions, sociodemographic variables, and self-assessment of health conditions on the projected probability to become obese in the postretirement age (67 years and older). …”
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