A multicenter, cross‐sectional analysis to assess the safety and usage pattern of brivaracetam in the management of partial‐onset seizure with BAEs—BREEZE study: A post‐hoc analysi... by Arvind Sharma, Krishnaprasad Korukonda, Amit Haldar, Usha Kant Misra, R. V. Anand, Yakshdeep Dave, Girish Kulkarni

“…Significance BRV remains a pertinent therapeutic choice for FoS for the treatment naïve and/or BAE cases. Exposure of LEV leads to considerable BAEs compared to patients without LEV exposure. …”
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Knockdown of Gfi1 increases BMSCs exosomal miR-150-3p to inhibit osteoblast ferroptosis in steroid-induced osteonecrosis of the femoral head through BTRC/Nrf2 axis by Liwen Zheng, Changjie Zhang, Lele Liao, Zhijie Hai, Xin Luo, Haoliang Xiao

“…MiR-150-3p directly targeted BTRC, leading to its downregulation in osteoblasts. The BTRC/Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway was involved in the inhibition of DEX-induced osteoblast ferroptosis by BMSCs-Exos-miR-150-3p. …”
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Ilaser Submucous Destruction in the Treatment of Hemorrhoids by S. A. Frolov, D. V. Vyshegorodtsev, A. M. Kuzminov, Yu. L. Trubacheva, V. Yu. Korolik, I. S. Bogormistrov, I. A. Mukhin, A. N. Ryndin, A. A. Anarbaeva

“…The absence of postoperative wounds in the anal canal leads to a decrease in pain syndrome, and by day 7 there are no clinical manifestations of hemorrhoids. …”
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The Rickettsia actin-based motility effectors RickA and Sca2 contribute differently to cell-to-cell spread and pathogenicity by Cuong J. Tran, Zahra Zubair-Nizami, Ingeborg M. Langohr, Matthew D. Welch

“…Our results suggest that actin-based motility effectors RickA and Sca2 drive two distinct forms of cell-to-cell spread and contribute differently to pathogenicity in the mammalian host.IMPORTANCERickettsia parkeri, a bacterium in the spotted fever group of Rickettsia species, can be transmitted from ticks to humans, leading to symptoms including fever, rash, muscle aches, and a lesion at the site of the tick bite. …”
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Association of extreme heat events with sleep and cardiovascular health: a scoping review by Nathan Ashe, Sarah Wozniak, Malcolm Conner, Rayan Ahmed, Olivia Keenan, Michelle R. Demetres, Nour Makarem, Parisa Tehranifar, Rajalakshmi Nandakumar, Arnab K. Ghosh

“…A possible mechanism leading to heat-related CVD is disturbances in sleep health, which can increase the risk of hypertension, and is associated with ideal cardiovascular health. …”
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Spectrum and Clinical Characteristics of Renal Diseases in Ghanaian Adults: A 13-Year Retrospective Study by Perditer Okyere, Isaac Okyere, Richard Kobina Dadzie Ephraim, Joseph Attakorah, Charlotte Osafo, Bernard Arhin, Sarah Bachelle, Albert Abaka-Yawson

“…Renal diseases over the years have become one of the leading causes of morbidity and mortality worldwide. …”
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Hubungan Indeks Massa Tubuh dengan Kejadian Preeklampsia di RSUP Dr. M. Djamil Padang by Cintya Andriani, Nur Indrawati Lipoeto, Bobby Indra Utama

“…</p><p><strong>Kata kunci:</strong> preeklampsia, faktor risiko, indeks massa tubuh</p><p> </p><p><strong><em>Abstract</em></strong></p><p><em>Preeclampsia is the leading cause of maternal death in addition to bleeding and infection. …”
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Functional Characterization of the <i>PoWHY1</i> Gene from <i>Platycladus orientalis</i> and Its Role in Abiotic Stress Tolerance in Transgenic <i>Arabidopsis thaliana</i> by Chun Ou, Zhiyu Dong, Xudong Zheng, Wenhui Cheng, Ermei Chang, Xiamei Yao

“…The frequent occurrence of extreme weather conditions in the world has brought many unfavorable factors to plant growth, causing the growth and development of plants to be hindered and even leading to plant death, with abiotic stress hindering the growth and metabolism of plants due to severe uncontrollability. …”
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Terminal complement complex deposition on chondrocytes promotes premature senescence in age- and trauma-related osteoarthritis by Leonie Ruths, Jana Hengge, Graciosa Q. Teixeira, Melanie Haffner-Luntzer, Anita Ignatius, Jana Riegger

“…BackgroundThe complement system is locally activated after joint injuries and leads to the deposition of the terminal complement complex (TCC). …”
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Perinatal outcomes and predictors of placental abruption: a retrospective study in an Ethiopian tertiary care center by Mesfin Tadese, Gebresenbet Getachew, Tirusew Nigussie Kebede, Toyba Ebrahim Yesuf, Saba Desta Tessema, Wogene Asefa Damesa, Gebeyehu Shumet Solomon

“…BackgroundPlacental abruption is a critical obstetric condition characterized by the premature separation of the placenta from the uterus, leading to severe maternal and fetal complications. …”
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Cardiac Myosin-binding Protein-C as a Biomarker in the Early Diagnosis of Acute Coronary Syndrome and Differentiation of Its Types by Ali Abdul Rasool Hussein, Abdulkareem Hamadi Issa, Abbas Naji Muslem Al Shareeifi

“…The ACS is manifested in one of three subtypes and it is the leading cause of mortality worldwide. The three subtypes of ACS include: acute myocardial infarction (MI) with the electrocardiogram (ECG) presenting ST-segment elevation (STEMI), MI with no ST-segment elevation on ECG (NSTEMI), and the third subtype is unstable angina (UA). …”
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MT1G promotes iron autophagy and inhibits the function of gastric cancer cell lines by intervening in GPX4/SQSTM1 by Kaiqiang Meng, Jian Song, Fan Qi, Jiamin Li, Zhichao Fang, Liang Song

“…Overexpression of MT1G promotes the transformation of LC3B I to LC3B II, reduces SQSTM1 protein expression, and leads to the appearance of more autophagosomes and autolysosomes at low magnification. …”
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Tradition and Development of Lithuanian Terminology by Antanas Smetona

“…Consequently, alongside original Lithuanian terminology, a considerable number of translated terms, calques, and foreign language influences emerged, leading to synonymy issues. Often a patriot or a man of science, who has returned or is returning to the Lithuanian language, has, to put it mildly, insufficient knowledge of Lithuanian word formation and grammar, and hence the rather poor quality of terminology emerges. …”
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From cellular senescence towards age-related macular degeneration: the role of telomeres by L.K. Moshetova, O.I. Abramova, K.I. Turkina, O.P. Dmitrenko, N.S. Karpova

“…This disease is the third leading cause of blindness in elderly patients after glaucoma and cataract. …”
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Evaluating the feasibility, sensitivity, and specificity of next-generation molecular methods for pleural infection diagnosis by Peter T. Bell, Timothy Baird, John Goddard, Olusola S. Olagoke, Andrew Burke, Shradha Subedi, Tiana R. Davey, James Anderson, Derek S. Sarovich, Erin P. Price

“…Limitations of conventional diagnostic tests result in prolonged and inappropriately broad-spectrum antimicrobial use, encouraging antimicrobial resistance and leading to avoidable adverse effects. Here, we demonstrate the feasibility, utility, and challenges associated with the use of culture-independent molecular techniques for accurate pleural infection diagnosis in a real-world clinical setting. …”
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Trends and ethnic disparity in endometrial cancer mortality in South Africa (1999-2018): A population-based Age-period-cohort and Join point regression analyses. by Gbenga Olorunfemi, Elena Libhaber, Oliver Chukwujekwu Ezechi, Eustasius Musenge

“…<h4>Background</h4>Endometrial cancer is the sixth leading cause of cancer among females and about 97,000 global deaths of endometrial cancer. …”
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Post-Hercynian ultrahigh-temperature tectono-metamorphic evolution of the Middle Atlas lower crust (central Morocco) revealed by metapelitic granulite xenoliths by A. El Maz, A. Vauchez, J.-M. Dautria

“…This event was followed by gradual cooling down to <span class="inline-formula">∼</span> 800 °C, leading to static crystallization of the felsic melt in the quartzo-feldspathic granulites. …”
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Preservative-free IOP-lowering medications: potential advantages by I.B. Alekseev, I.A. Koroleva

“…Koroleva²<br> </p> <p> ¹Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation </p> <p> ²City Clinical Hospital No. 15, Moscow, Russian Federation </p> <p> <i>According to the World Health Organization, glaucoma is the second leading cause of blindness in the world. Pharmacotherapy for glaucoma implies long-term instillations of IOP-lowering drugs. …”
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Influencing basic behavioral mechanisms of action while targeting daily walking in sedentary adults at risk for cardiovascular disease: randomised factorial design protocol by Karina W Davidson, Ying Kuen Cheung, Joan Duer-Hefele, Jerry Suls, Ashley M Goodwin, Samantha Gordon, Ravneet Sahni, Frank Vicari, Kaitlyn Accardi, Salvatore Crusco, Ciaran Friel, Elizabeth A Vrany

“…Introduction Cardiovascular disease (CVD) is the leading cause of mortality worldwide, though it may be prevented by increasing physical activity (PA). …”
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Lowering light intensity while extending photoperiod at a constant daily light integral synergistically interacts with warm temperature to enhance leaf expansion and crop yield in... by Sang Jun Jeong, Sang Jun Jeong, Shuyang Zhen, Qianwen Zhang, Qianwen Zhang, Genhua Niu

“…However, under strong shade signals composed of FR light, low light intensity, and warm temperature, lettuce prioritizes stem elongation at the expense of leaf expansion, leading to reduced crop yield.…”
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