PPARα suppresses growth of hepatocellular carcinoma in a high-fat diet context by reducing neutrophil extracellular trap release by Banglun Pan, Zhu Zhang, Dongjie Ye, Xiaoxia Zhang, Yuxin Yao, Yue Luo, Haijie Hong, Xinran Cai, Yanling Chen, Nanhong Tang

“…The presence of a HFD was observed to induce mitochondrial impairment in neutrophils, leading to the activation of cGAS-STING by oxidized mitochondrial DNA (Ox-mtDNA). …”
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Comparison of Tropospheric Horizontal Gradients Modeling Methods in LEO Constellation Augmented GNSS Precise Point Positioning by Xinyu Zhang, Wenwu Ding, Xiaochuan Qu, Hongjin Xu, Xuanzhao Tan, Yunbin Yuan

“…In comparison, the analysis of slant path delays accuracy for elevation below 10° shows that the directional model is more suitable for low elevation observations, but the introduction of too many redundant parameters leads to a decrease in the accuracy at high elevation angles. …”
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Development of a standardized patient-reported clinical questionnaire for children with spinal pain by Freja Gomez Overgaard, Henrik Hein Lauridsen, Mads Damkjær, Anne Reffsøe Ebbesen, Lise Hestbæk, Mikkel Brunsgaard Konner, Søren Francis Dyhrberg O’Neill, Stine Haugaard Pape, Michael Skovdal Rathleff, Christian Lund Straszek, Casper Nim

“…The second phase involved pilot testing among pediatric spinal pain patients, leading to modifications for improved clarity and relevance. …”
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Impaction bone grafting for acetabular bone defects replacement in revision hip arthroplasty: biomechanical aspects by Vadim N. Golnik, Natalia V. Fedorova, Alexey Y. Larichkin, Svetlana V. Boyko, Andrey A. Panchenko, Alexandr M. Kosinov, Vladimir A. Peleganchuk, Vitaliy V. Pavlov

“…Background. The leading role in long-term survival of the prosthesis installed using impaction bone grafting is given to the mechanical properties of the graft. …”
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Hydrogen Sulfide Promotes Functional Endometrium Recovery via Regulating Pyroptosis in Severe Endometrial Injury: A Prospective Laboratory Based Randomized Control Trial by Haiyan Shan, Mingyuan Xu, Jie Ni, Ling Zhou, Mengchun Xue, Jun Xue, Xiaohuan Yuan, Luyang Tao, Mingyang Zhang, Hong Zhang

“…Background: Severe endometrial injury constitutes a significant risk to female fertility, often leading to the development of intrauterine adhesions. …”
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Clinical utility and predictive value of cerebrospinal fluid cell-free DNA profiling in non-small cell lung cancer patients with leptomeningeal metastasis by Sheng-Kai Liang, Wei-Yu Liao, Jin-Yuan Shih, Chia-Lin Hsu, Ching-Yao Yang, Shang-Gin Wu, Yen-Ting Lin, Yueh-Feng Wen, Lun-Che Chen, Yen-Fu Chen, Ya-Fang Chen, Yen-Heng Lin, Chong-Jen Yu

“…MET CNG positively impacts survival for ITP recipients, whereas the coexistence of EGFR T790M and EGFR-independent resistance mechanisms leads to poor outcomes.…”
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Evaluating the efficacy of carbetocin versus oxytocin for preventing intraoperative blood loss, early postpartum hemorrhage, and maintaining a favorable hemodynamic profile in lowe... by Bisma Fayaz, Raja Suhail Shounthoo, Ajaiz Rasool, Saima Wani, Showkat Ahmad Gurcoo

“…Carbetocin has a significantly longer half-life than oxytocin, potentially leading to more sustained uterine contractions and reduced blood loss. …”
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The global, regional, and national burden of type 2 diabetes mellitus attributable to low physical activity from 1990 to 2021: a systematic analysis of the global burden of disease... by Jiehua Wei, Luying Fan, Zixuan He, Senmao Zhang, Ying Zhang, Xidi Zhu, Fan Xia, Xinli Song, Lizhang Chen, Zhiyong Zou, Tingting Wang

“…Abstract Background Low physical activity (LPA) is a leading risk factor for type 2 diabetes mellitus (T2DM). …”
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Application of trichloroisocyanuric acid in controlling kiwifruit bacterial canker disease demonstrates its promising potential as an eco-friendly bactericide by Jianyou Gao, Jiewei Li, Cuixia Liu, Hongjuan Gong, Beibei Qi, Rongxiang Zhu, Liming Xia, Li Li, Shibiao Liu, Qiaosheng Jiang, Kaiyu Ye, Faming Wang

“…Mechanistic investigations revealed that TCCA inhibited bacterial biofilm formation, impaired motility, disrupted cell integrity, and suppressed the expression of virulence-related genes, ultimately leading to bacterial cell death. Additionally, TCCA treatment of both healthy and infected canes induced the activity of key defense-related enzymes, including catalase (CAT), peroxidase (POD), glutathione reductase (GR), and phenylalanine ammonia-lyase (PAL), suggesting that TCCA may activate systemic plant defense responses. …”
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Enhanced Control Efficacy of Different Insecticides Mixed with Mineral Oil Against Asian Citrus Psyllid, <i>Diaphorina citri</i> Kuwayama, Under Varying Climates by Wei Hu, Kejing Wang, Xiaoyue Zhong, Pei Jiang, Shunchang Zhang, Zhanjun Lu, Zhixiang Zhang, Long Yi, Ning Zhang

“…Moreover, the rainfastness of THX was improved after adding LY, leading to a greater retention on the leaves. LY at a rate of 1.0% exhibited excellent efficacy against ACP nymphs, and observations using scanning electron microscopy (SEM) showed that LY altered ACP mouthpart morphology and blocked spiracles, likely contributing to its insecticidal effects. …”
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Economic impact of heart failure with preserved ejection fraction: insights from the ALDO‐DHF trial by Djawid Hashemi, Ludwig Dettmann, Tobias D. Trippel, Volker Holzendorf, Johannes Petutschnigg, Rolf Wachter, Gerd Hasenfuß, Burkert Pieske, Antonia Zapf, Frank Edelmann

“…Abstract Aims Although heart failure (HF) with preserved ejection fraction (HFpEF) is a leading cause for hospitalization, its overall costs remain unclear. …”
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An interval bilateral regulation framework of water resources supply and demand in irrigation area under water sources uncertainty by Zhan Shu, Yan Kang, Ying Gao, Xuemai Shi, Wanxue Li, Shuo Zhang, Songbai Song, Lingjie Li

“…Climate change and human activities have diminished the stability of the water resources system, leading to multiple uncertainties in the prediction of incoming water, reservoir operation optimization on the water supply side, and adaptive adjustments of the water-use structure on the water demand side. …”
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Amending the algorithm of aerosol–radiation interactions in WRF-Chem (v4.4) by J. Feng, C. Zhao, C. Zhao, C. Zhao, C. Zhao, C. Zhao, C. Zhao, Q. Du, Z. Yang, C. Jin

“…The modification also leads to changes in meteorological fields due to alterations in radiative feedback effects of aerosols. …”
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Genome-wide linkage mapping of Fusarium crown rot in common wheat (Triticum aestivum L.) by Faji Li, Can Guo, Qi Zhao, Weie Wen, Shengnan Zhai, Xinyou Cao, Cheng Liu, Dungong Cheng, Jun Guo, Yan Zi, Aifeng Liu, Jianmin Song, Jianjun Liu, Jindong Liu, Haosheng Li

“…IntroductionFusarium crown rot (FCR) is a severe soil-borne disease that affects wheat globally and leads to significant yield reductions. Identifying the loci associated with resistance to FCR and developing corresponding markers are essential for the breeding of resistant wheat varieties.MethodsIn this study, we evaluated the resistance to FCR in a recombinant inbred line (RIL) population originating from Gaocheng 8901 and Zhoumai 16 across four environments. …”
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Robust and Long-Lasting Immunity and Protection in Mice Induced by Lipopolyplex-Delivered mRNA Vaccines Expressing the Prefusion Protein of Respiratory Syncytial Virus by Xuchang Shan, Ruiwen Han, Xueting Cheng, Jialuo Bing, Zhenyong Qi, Shucai Sun, Tangqi Wang, Qiaohong Chu, Yao Deng, Desheng Zhai, Wenjie Tan

“…Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections in infants and children. mRNA vaccines based on the lipopolyplex (LPP) platform have been previously reported, but they remain unapplied in RSV vaccine development. …”
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Spatial transcriptomics reveals unique metabolic profile and key oncogenic regulators of cervical squamous cell carcinoma by Limin Zhou, Jiejie Liu, Peipei Yao, Xing Liu, Fei Chen, Yu Chen, Li Zhou, Chao Shen, You Zhou, Xin Du, Junbo Hu

“…Coupled with single-cell RNA sequencing (scRNA-seq) data after deconvolution, we described spatial distribution maps of tumor leading edge and core regions in detail. Tumor tissues were classified into hypermetabolic and hypometabolic regions to analyze the metabolism profiles and tumor differentiation degree across different spatial areas. …”
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Hypermethylation in Calca Promoter Inhibited ASC Osteogenic Differentiation in Rats with Type 2 Diabetic Mellitus by Lei Wang, Feng Ding, Shaojie Shi, Xingxing Wang, Sijia Zhang, Yingliang Song

“…The abnormal environment of type 2 diabetes mellitus (T2DM) leads to a substantial decrease in osteogenic function of stem cells. …”
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Hypercalcemia Following Adrenalectomy for Cushing Syndrome in a Patient with Post-Surgical Hypoparathyroidism by Pietro Locantore, Alessandro Oliva, Gianluca Cera, Rosa Maria Paragliola, Roberto Novizio, Caterina Policola, Andrea Corsello, Alfredo Pontecorvi

“…During her follow-up, an ACTH-independent Cushing syndrome was diagnosed, leading to a unilateral right adrenalectomy. In the two months following surgery, she was admitted to the emergency ward on three occasions because of severe, persistent, idiopathic hypercalcemia. …”
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Mineralogical and geochemical characteristics of the third member of Palaeogene Dongying formation in the Nanpu Sag, Bohai Bay Basin: implications for controlling on organic matter... by Shiyan Yin, Shiyan Yin, Aidong Yao, Jianzhong Cheng, Chuang Lei, Zhaosheng Wang, Zhenguo Zhang, Ying Zhang, Yu Wang, Xiaoying Han, Zhigang Ma

“…Here, aquatic organic matter was oxidized and degraded in the oxidation condition, leading to low organic matter accumulation.DiscussionThe exploration of unconventional shale oil in the Ed3 member of Nanpu Sag should focus on the organic-matter-rich mudstones developed in the humid climate.…”
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High Data-Rate Hilbert-Curved-Shaped MIMO Antenna With Improved Bandwidth and Circular Polarization for Wireless Capsule Endoscopy by Syed Misbah Un Noor, Syed Ahson Ali Shah, Shahid Khan, Izaz Ali Shah, Jamal Nasir, Salahuddin Khan, Slawomir Koziel

“…The proposed MIMO antenna, with its superb dominant characteristics, outperforms leading state-of-the-art endoscopic antennas, offering promising advancements for capsule endoscopy systems.…”
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