5′-UTR allelic variants and expression of the lycopene-ɛ-cyclase <i>LCYE</i> gene in maize (<i>Zea mays</i> L.) inbred lines of Russian selection by D. Kh. Arkhestova, B. R. Shomakhov, A. V. Shchennikova, E. Z. Kochieva

“…The parallel β,ε-branch is triggered by lycopene-ε-cyclase LCYE, a low expression of which leads to an increase in provitamin A content and is associated with the variability    of the 5’-UTR gene regulatory sequence. …”
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Cutaneous amyloidosis in the orbital region (case report) by A.N. Bochkareva, V.V. Egorov, O.V. Kolenko, G.P. Smolyakova, P.A. Banshchikov

“…Fyodorov Eye Microsurgery Federal State Institution, Khabarovsk, Russian Federation </p> <p> ²Institute of Advanced Training of Healthcare Specialists, Khabarovsk, Russian Federation </p> <p> Amyloidosis is an extracellular mesenchymal dysproteinosis characterized by deposition of amyloid in tissues, parenchymal atrophy and functional organ failure leading to fatal outcomes. A significant problem of this disease for a doctor of any specialty remains a long period of establishing a clinical diagnosis. …”
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Measurement error in remotely sensed fractional snow cover datasets: implications for ecological research by Rowan Jacques-Hamilton, Mihai Valcu, Eunbi Kwon, Tom S L Versluijs, Bart Kempenaers

“…We found that satellite datasets tended to overestimate FSC, leading to late estimates for snow melt dates. The Sentinel-2 dataset gave the most accurate results, followed by VIIRS, with MODIS giving the least accurate results. …”
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Joint Analysis of Transcriptome and Metabolome at Different Leaf Color Stages of Cymbidium sinense 'Red Sun' by Jie GAO, Chuyan XIANG, Junhong ZHAO, Qiming PAN, Fengxi YANG

“…【Conclusion】The reduction in the content of anthocyanin synthesis precursors and the expression levels of related synthetic enzyme genes leads to the gradual disappearance of the red color in leaves of C. sinense 'Red Sun', and the high expression of photosynthetic pigment synthesis-related genes is the main reason for the leaves of C. sinense 'Red Sun' changing from yellow to green.…”
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The Impact of Optical Undersampling on the Ca2+ Signal Resolution in Ca2+ Imaging of Spontaneous Neuronal Activity by Katarina D. Milicevic, Violetta O. Ivanova, Tina N. Brazil, Cesar A. Varillas, Yan M.D. Zhu, Pavle R. Andjus, Srdjan D. Antic

“…Conclusions: Our findings reveal that Ca2+ signal undersampling leads to three types of information loss: (1) distortion of rise times and durations for large-amplitude transients, (2) failure to detect small-amplitude transients in cell bodies, and (3) omission of small-amplitude transients in the neuropil.…”
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Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-a... by Khalid W. Helmi, Ahmed S. Abdulhamid, Mohammed S. Alomari, Ali S. Alsudais, Badran S. Alqurashi, Abdullah Alsharif, Abdulrahman H. Alzahrani, Abdulrahman M. Bahalaq, Mohammed F. Qutub, Hashem S. Almarzouki

“…Abstract Background Primary acquired nasolacrimal duct obstruction (PANDO) is a condition in which tear ducts are blocked, leading to epiphora and dacryocystitis. This systematic review and meta-analysis aimed to measure the ability of transcanalicular dacryocystorhinostomy (TC-DCR) as an alternative approach to PANDO compared to traditional external dacryocystorhinostomy (EX-DCR). …”
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Evaluation of the Expression of Infection-Related Long Noncoding RNAs among COVID-19 Patients: A Case-Control Study by Zahra Firoozi, Elham Mohammadisoleimani, Farzaneh Bagheri, Atefeh Taheri, Babak Pezeshki, Mohammad Mehdi Naghizadeh, Abdolreza Daraei, Jalal Karimi, Yousef Gholampour, Yaser Mansoori, Zahra Montaseri

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a worldwide pandemic, activates signaling cascades and leads to innate immune responses and secretion of multiple chemokines and cytokines. …”
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DIGITALIZATION OF THE ECONOMY AS THE BASIS OF HUMAN CAPITAL POTENTIAL by Ahmadova Akima Amir, Rzayev Mirza Agharza, İsmayilova Lala Hamlet, Muradova Jala Nizami

“…The digital transformation of modern society has a profound impact on traditional human capital, as the active adoption of digitalization leads to the intellectualization of labor. In the context of a digitized economy, human capita – its development and level – becomes a key driver of economic growth and national prosperity. …”
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Performance of Banana Peelings Extract as A Natural Coagulant in the Treatment of Surface Water Case Study: River Rwizi, Mbarara. by Asingya, Derrick

“…The existence of suspended solids and other pollutants in water leads to countless drawbacks during water treatment creating deleterious disinfection by-products such as trihalomethanes, Dichlorobromomethane and Trichloroacetic acid after the use of chemical coagulants, which are potentially deleterious to human health and the environment. …”
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Youth Involvement in Pornography and Academic Engagement in Selected Secondary Schools in Kabale Municipality. by Kanyesigye, Bens Rogers

“…The key findings from the study revealed that watching videos of naked persons on computers in the computer lab is the leading form of pornography (M=4.61, SD=.490), while on the sources of pornography, indecent dressing while showing private body parts was considered a major source of pornographic material (M=4.61, SD=.490). …”
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Genetic diversity and population structure of Plasmodium falciparum across areas of varied malaria transmission intensities in Uganda. by Mwesigwa, Alex, Tukwasibwe, Stephen, Cummings, Bryan, Kawalya, Hakiimu, Kiyaga, Shahiid, Okoboi, Stephen, Castelnuovo, Barbara, Bikaitwoha, Everd Maniple, Kalyango, Joan N., Nsobya, Samuel L., Karamagi, Charles, Byakika‑Kibwika, Pauline, Nankabirwa, Joaniter I.

“…Plasmodium falciparum is the predominant species in the region, leading to substantial morbidity and mortality. Despite intensified control efforts over the last two decades, P. falciparum genetic diversity and multiplicity of infections (MOI) continue to pose significant challenges to malaria elimination in the region. …”
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Factors Associated with Stunting in Children Under Five Years of Age: A Case of Buhara Sub County, Kabale District. by Namanya, Oliver

“…The study recommended that, Kabale District local government in conjunction with Buhara Sub County leadership should come up with ordinances and byelaws on how to improve community sanitation and hygiene practices especially improving toilet coverage, hand washing and proper disposal of the wastes to avoid stunting as they pose great risk to diarrheal diseases leading to mal-absorption food. Keywords Stunting Children, Under Five Years, Age, Buhara Sub-County, Kabale District.…”
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The impact of biofeedback in enhancing chronic pain rehabilitation: A systematic review of mechanisms and outcomes by Andrea Calderone, Vincenza Maura Mazzurco Masi, Rosaria De Luca, Antonio Gangemi, Mirjam Bonanno, Daniela Floridia, Francesco Corallo, Giovanni Morone, Angelo Quartarone, Maria Grazia Maggio, Rocco Salvatore Calabrò

“…Mechanistically, BFB facilitates improved self-regulation by training patients to modulate physiological responses, such as muscle tension and heart rate variability, leading to better pain control and stress reduction. …”
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Intranigral Administration of β-Sitosterol-β-D-Glucoside Elicits Neurotoxic A1 Astrocyte Reactivity and Chronic Neuroinflammation in the Rat Substantia Nigra by Claudia Luna-Herrera, Irma A. Martínez-Dávila, Luis O. Soto-Rojas, Yazmin M. Flores-Martinez, Manuel A. Fernandez-Parrilla, Jose Ayala-Davila, Bertha A. León-Chavez, Guadalupe Soto-Rodriguez, Victor M. Blanco-Alvarez, Francisco E. Lopez-Salas, Maria E. Gutierrez-Castillo, Bismark Gatica-Garcia, America Padilla-Viveros, Cecilia Bañuelos, David Reyes-Corona, Armando J. Espadas-Alvarez, Linda Garcés-Ramírez, Oriana Hidalgo-Alegria, Fidel De La Cruz-lópez, Daniel Martinez-Fong

“…Chronic consumption of β-sitosterol-β-D-glucoside (BSSG), a neurotoxin contained in cycad seeds, leads to Parkinson’s disease in humans and rodents. …”
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Depression screening using patient-targeted feedback in general practices: study protocol of the German multicentre GET.FEEDBACK.GP randomised controlled trial by Joachim Szecsenyi, Hans-Helmut König, Karl Wegscheider, Martin Härter, Bernd Löwe, Antonius Schneider, Martin Scherer, Jürgen Gallinat, Antonia Zapf, Sebastian Kohlmann, Marco Lehmann, Marion Eisele, Lea-Elena Braunschneider, Gabriella Marx, Stefanie Joos, Gaby Resmark, Christine Allwang, Christoph Nikendei, Sven Schulz, Katja Brenk-Franz

“…A previous single-centre randomised controlled trial (RCT) in cardiac patients, the DEPSCREEN-INFO trial, provided the first evidence that written feedback to patients following a positive depression screening reduces depression severity and leads to more comprehensive patient engagement in mental healthcare. …”
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Oxidative Stress Induced Damage and Early Senescence in Preterm Placenta by Yudianto Budi Saroyo, Noroyono Wibowo, Rima Irwinda, Ani Retno Prijanti, Evy Yunihastuti, Saptawati Bardosono, Sofie Rifayani Krisnadi, Putri Indah Permata, Stephanie Wijaya, Victor Prana Andika Santawi

“…Further research is needed to discover the factors leading to early telomere shortening in the placenta of preterm birth.…”
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Effectiveness of a pharmacist-led tele-psychiatric clinic in managing drug-related problems by Majed Al Shakhori, Savera Arain, Suhaj Abdulsalim, Mohammed Salim Karattuthodi, Marwa Al Dhamen, Shoruq Almutairi, Shabeer Ali Thorakkattil, Dina Alahmdi, Vijayanarayana Kunhikatta, Abdul Sammad AlJishi

“…Additionally, the research assessed physicians' acceptance of pharmacists' recommendations for managing these DRPs.Methods: A cohort retrospective study was conducted at a leading tertiary care hospital in Saudi Arabia spanning from January 2023 to January 2024 in a psychiatry setting. …”
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Molecular-genetic pathways of hepatitis C virus regulation of the expression of cellular factors PREB and PLA2G4C, which play an important role in virus replication by E. L. Mishchenko, A. A. Makarova, E. A. Antropova, A. S. Venzel, T. V. Ivanisenko, P. S. Demenkov, V. A. Ivanisenko

“…We assumed that NS3 could inhibit the function of host transcription factor (TF) NOTCH1 by protein-protein interaction, leading to upregulation of PREB and PLA2G4C. Analysis of the gene networks and data on differential gene expression in HCV-infected cells allowed us to hypothesize further how HCV could regulate the expression of TFs, the binding sites of which are localized within PREB and PLA2G4C gene regions. …”
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Global Mean and Relative Sea-Level Changes Over the Past 66 Myr: Implications for Early Eocene Ice Sheets by K. G. Miller, W. J. Schmelz, J. V. Browning, Y. Rosenthal, A. V. Hess, R. E. Kopp, J. D. Wright

“…Both the BSL and RSL estimates have markedly higher Oligocene to Early Miocene Myr-scale amplitudes (20–60 m) than recently published δ18O-based estimates (<20 m) and much lower estimates than those of Exxon Production Research (>100 m), leading us to reject those estimates. The US Mid-Atlantic margin RSL was dominated by GMGSL but was overprinted by changes in mantle dynamic topography on the several Myr scale, showing approximately 50 m higher Eocene estimates and regionally propagating Miocene RSL changes.…”
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The effect of baseline versus early glucocorticoid use on immune checkpoint inhibitor efficacy in patients with advanced NSCLC by Yifan Wang, Yifan Wang, Jianying Zhou, Simin Peng, Simin Peng, Zhao Cui, Zhao Cui, Weiqi Wang, Weiqi Wang, Wenqin Zeng, Wenqin Zeng, Tingting Qiu, Zhentian Liu

“…In particular, GC use during the baseline period leads to higher ORR and PFS, regardless of the dose or duration of GC use. …”
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