OCT Biomarkers in Neovascular Age-Related Macular Degeneration: A Narrative Review by Cristian Metrangolo, Simone Donati, Marco Mazzola, Liviana Fontanel, Walter Messina, Giulia D’alterio, Marisa Rubino, Paolo Radice, Elias Premi, Claudio Azzolini

“…Age-related macular degeneration (AMD) is the leading cause of legal blindness in elderly people. …”
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Multidrug-resistant ESBL E. coli in urban surface waters and public health implications: A Case Study from Goranchatbari, Dhaka by Md. Sakib Hossain, Ahmed Ishtiaque Amin Chowdhury, Mohammad Rafiqul Islam, Ripan Kirtunia, Md. Foysal Abedin, Mohammad Atique Ul Alam, Shampa, Sonia Binte Murshed, Md Shadman Sakib, Siam Alam, M. Shahjahan Mondal, Zahid Hayat Mahmud

“…These water sources critically threaten public health by contaminating nearby freshwater sources with ESBL-producing pathogenic isolates, leading to various hard-to-treat waterborne diseases and risking aquatic biota by deteriorating water quality. …”
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Real-world clinical evidence of oral semaglutide on metabolic abnormalities in subjects with type 2 diabetes: a multicenter retrospective observational study (the Sapporo-Oral SEMA... by Sho Furusawa, Hiroshi Nomoto, Chiho Oba-Yamamoto, Jun Takeuchi, Miki Ito, Hiroyoshi Kurihara, Shin Aoki, Aika Miya, Hiraku Kameda, Akinobu Nakamura, Tatsuya Atsumi

“…The changes in glycated hemoglobin, body weight, and other metabolic parameters were evaluated and any adverse event leading to semaglutide discontinuation were recorded from February 2021 to December 2022. …”
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Compound weather and climate extremes in the Asian region: science-informed recommendations for policy by R. Krishnan, Chirag Dhara, Takeshi Horinouchi, C. Kendra Gotangco Gonzales, C. Kendra Gotangco Gonzales, A. P. Dimri, A. P. Dimri, M. Singh Shrestha, P. Swapna, M. K. Roxy, Seok-Woo Son, Seok-Woo Son, D. C. Ayantika, Faye Abigail T. Cruz, Fangli Qiao

“…Anthropogenic climate change has led to rapid and widespread changes in the atmosphere, land, ocean, cryosphere, and biosphere, leading to more pronounced weather and climate extremes globally. …”
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SMRT sequencing and ddPCR reveal the complexity of developmental trajectories and temporal dynamics of gut bifidobacterial communities in infants by Xu Gao, Tao Zhang, Xiaoye Bai, Qiannan Wen, Dongyu Li, Lai-Yu Kwok, Heping Zhang, Zhihong Sun

“…The infant microbiota showed highly individualized developmental trajectories. The leading species for GF was B. catenulatum, with a relatively stable developmental trajectory. …”
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Is avoidable diabetes-related hospitalization in older patients with type 2 diabetes mellitus associated with increased health expenditure?: A nationwide retrospective cohort study... by Woo-Ri Lee, Gyeong-Min Lee, Noorhee Son, Kyu-Tae Han, Sungyoun Chun, Yehrhee Son, Ki-Bong Yoo

“…Objective: With South Korea's population aging rapidly, the number of patients with type 2 diabetes mellitus (T2DM) is expected to rise, leading to worsened health outcomes and potentially straining healthcare financing. …”
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CC-96673 (BMS-986358), an affinity-tuned anti-CD47 and CD20 bispecific antibody with fully functional fc, selectively targets and depletes non-Hodgkin’s lymphoma by Dan Zhu, Haralambos Hadjivassiliou, Catherine Jennings, David Mikolon, Massimo Ammirante, Sharmistha Acharya, Jon Lloyd, Mahan Abbasian, Rama Krishna Narla, Joseph R. Piccotti, Katie Stamp, Ho Cho, Kandasamy Hariharan

“…To date, the advancement of CD47-targeted modalities is hindered by the ubiquitous expression of the target, often leading to rapid drug elimination and hematologic toxicity including anemia. …”
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Evaluating implementation of a hospital‐based cancer registry to improve childhood cancer care in low‐ and middle‐income countries by Melissa R. Maas, Allison Yang, Michele A. Muir, James B. Collins IV, Courtney Canter, Gevorg Tamamyan, Inam Chitsike, Francine Kouya, Kim Hoa Nguyen, Alia Ahmad, Ana Patricia Alcasabas, Yi‐Jin Gao, Kimberly J. Johnson, Gia Ferrara, Nickhill Bhakta, Benyam Muluneh

“…Abstract Purpose Cancer is a leading cause of global childhood mortality, affecting 400,000 children annually. …”
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Long term safety and efficacy of ligelizumab in the treatment of Japanese patients with chronic spontaneous urticaria by Hidetoshi Takahashi, Atsushi Fukunaga, Koremasa Hayama, Takayoshi Sasajima, Ayako Fujishige, Ryohei Ichishita, Naoko Tomimatsu, Eva Hua, Vineeth Varanasi, Alis Burciu, Michihiro Hide, Thomas Severin

“…Results: From a total of 66 CSU patients (80.3% females; mean ± SD age 46.4 ± 13.2 years; mean ± SD baseline UAS7 28.7 ± 6.5) enrolled, 53 patients (80.3%) reported ≥1 TEAE during the study, with no severe or serious adverse events, no anaphylaxis events and low frequency of TEAEs leading to treatment discontinuations (6.1%). Absolute mean CFB of UAS7 showed a rapid onset of response at Week 4 (−14.2) with further improvement until end of treatment at Week 52 (−22.9). …”
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Biogenic synthesis of titanium nanoparticles by Streptomyces rubrolavendulae for sustainable management of Icerya aegyptiaca (Douglas) by Enayat M. Elqady, Eman El-said, Asmaa A. Tharwat, Lina A. Abou El-Khashab, Inas M. Y. Mostafa, Fatma Z. Hamed, Wesam M. Morsi, Mohamed M. Rezk, Inas M. Abou El-Enain

“…Icerya aegyptiaca (Douglas) is a pest that has many generations per year and can affect 123 plant species from 49 families by absorbing sap from bark, forming honeydew, causing sooty mold, and attracting invasive ant species, leading to significant agricultural losses. The purpose of this work was to synthesize titanium dioxide nanoparticles (TiO2-NPs) from marine actinobacteria and evaluate their insecticidal effects on Icerya aegyptiaca (Hemiptera: Monophlebidae), in addition to explaining their effects on protein electrophoresis analysis of SDS‒PAGE proteins from control and treated insects after 24, 72 and 120 h of exposure. …”
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Fuel starvation in automotive PEMFC stacks: stack current and bipolar plate resistance by Jens Nissen, Jan-Peter Boye, Max Schrievers, Jan Nicolas Schwämmlein, Markus Hölzle

“…These reactions are known to cause oxidation of the carbon in the anode catalyst layer, leading to performance degradation. This study demonstrates that FGS situations may furthermore cause a detrimental overheating behavior at high stack current. …”
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The Protective Effect of Anthocyanins Extracted from Aronia Melanocarpa Berry in Renal Ischemia-Reperfusion Injury in Mice by Li Li, Jun Li, Hui Xu, Fengmei Zhu, Zhijun Li, Hongzhi Lu, Jinrong Zhang, Zhengsheng Yang, Yongsheng Liu

“…Ischemia acute kidney injury is a significant risk in developing progressive and deterioration of renal function leading to clinic chronic kidney disease. There were many attempts to protect the kidney against this progression of renal damage. …”
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Impact of secondary ice production on thunderstorm electrification under different aerosol conditions by S. Huang, J. Yang, J. Yang, J. Li, Q. Chen, Q. Zhang, F. Guo

“…The warm-rain process is suppressed, and the declined raindrop concentration leads to fewer graupel particles. In a clean environment (aerosol concentration <span class="inline-formula">&lt;1000</span> <span class="inline-formula">cm⁻³</span>), the SD process is the most important to ice production between 0 and <span class="inline-formula">−10</span> °C, while in a polluted environment (aerosol concentration <span class="inline-formula">≥2000</span> <span class="inline-formula">cm⁻³</span>), the RS process contributes the most between 0 and <span class="inline-formula">−10</span> °C. …”
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Shexiang Tongxin dropping pills ameliorate myocardial ischemia-reperfusion injury progression via the S1PR2/RhoA/ROCK pathway by Ying Sun, Boyang Jiao, Yizhou Liu, Ran Wang, Qiong Deng, David N. Criddle, Yulin Ouyang, Wei Wang, Xuegong Xu, Chun Li

“…The S1PR2/RhoA/ROCK pathway was inhibited by STDP in vitro, leading to the regulation of endothelial cell TJs, adhesion junctions, and cytoskeletal morphology. …”
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AgIn2 thickness on void rate, microstructure, IMC growth, thermal and mechanical properties of fluxless In@AgIn2 joint by Jing Wen, Guoliao Sun, Jinyang Su, Yi Fan, Linzheng Fu, Zhuo Chen, Wenhui Zhu

“…However, organic flux residues trapped within the In solder during indium reflow process can outgas during subsequent solder ball reflow cycles, leading to the formation of significant voids (up to 35% void fraction) in the In TIM1. …”
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Improving the integrity and reproducibility of research that uses antibodies: a technical, data sharing, behavioral and policy challenge by M. Biddle, P. Stylianou, M. Rekas, A. Wright, J. Sousa, D. Ruddy, M. I. Stefana, K. Kmiecik, A. Bandrowski, R.A. Kahn, C. Laflamme, E. M. Krockow, H.S. Virk

“…Yet many antibodies used in research do not recognize their intended target, or recognize additional molecules, compromising the integrity of research findings and leading to waste of resources, lack of reproducibility, failure of research projects, and delays in drug development. …”
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Design of INSPIRE: Evaluation of the effectiveness of practice facilitation on implementation of screening, brief interventions, referral to treatment and medication for unhealthy... by Jennifer Bannon, Justin D. Smith, Mark J. Van Ryzin, Megan McHugh, Jennifer Heinrich, Theresa L. Walunas, Abel N. Kho

“…Background: Unhealthy alcohol use is a leading cause of preventable mortality and a risk factor for an array of social and health problems. …”
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Trends in the Use of Sphingosine 1 Phosphate in Age-Related Diseases: A Scientometric Research Study (1992-2020) by Qiong He, Gaofeng Ding, Mengyuan Zhang, Peng Nie, Jing Yang, Dong Liang, Jiaqi Bo, Yi Zhang, Yunfeng Liu

“…The USA (n=175), China (n=42), and Germany (n=37) were the three largest contributors to the global publications on S1P and aging, while the Medical University of South Carolina (n=15), University of California, San Francisco (n=13), and University of Toronto (n=13) were the leading institutions in this field. Analysis showed that early studies primarily focused on the mechanism of S1P intervention in AD. …”
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Analysis of the dynamics of occupational morbidity and its consequences in Ukraine in comparison with other countries of the world by M.H. Prodanchuk, A.V. Basanets, O.P. Kravchuk, K.Y. Hashynova, V.A. Hvozdetskyy

“…Obvious distortion of statistical indicators on occupational morbidity and related consequences leads to inconsistency in determining priority areas of health care activity. …”
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Rationale and design for Healthy Hearts in Manufacturing (HHM): A pragmatic single-arm hybrid effectiveness-implementation study for hypertension management and tobacco cessation by Hanzi Jiang, Yao Tian, Jennifer Bannon, Amy E. Krefman, Lawrence C. An, Dustin D. French, Claude R. Maechling, Jane Holl, Richard Chagnon, Theresa L. Walunas, Christopher Burch, Anthony Musci, Darce Latsis, Dawn Carey, Megan McHugh

“…Background: Heart disease is the leading cause of mortality in the United States and contributes more than $320 billion annually in health care costs and lost productivity. …”
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