Identification of Heat-Responsive Genes in Guar [Cyamopsis tetragonoloba (L.) Taub] by Aref Alshameri, Fahad Al-Qurainy, Abdel-Rhman Gaafar, Salim Khan, Mohammad Nadeem, Saleh Alansi

“…The threat of heat stress on crop production increased dramatically due to global warming leading to the rise on the demand of heat-tolerant crops and understanding their tolerance. …”
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N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1 by Li Xu, Shuo Chen, Qiuling Fan, Yonghong Zhu, Hang Mei, Jiao Wang, Hongyuan Yu, Ying Chen, Fan Liu

“…Conclusions Our findings suggest that the m6A modification of GLIS1, activated by METTL3 and reduced in a YTHDF1-dependent manner, leads to kidney aging by regulating the metabolic shift from FAO to glycolysis. …”
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Evaluating the influence of anti-PD-1 immunotherapy combined with IMRT on thyroid dysfunction in nasopharyngeal carcinoma by Liqianqi Chen, Zihuang Li, Xianming Li, Shihai Wu, Long Gong, Gang Xu, Shanyi Chen, Yucong Zhang

“…However, its potent anti-tumor effects can also attack normal tissues and organs, leading to immune-related adverse effects (irAE), with the thyroid being one of the most commonly affected organs. …”
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Experimental Investigation of the Effect of Two-Stage Peltier Application on the Temperature of a Microprocessor by Fatih Uysal, Sinan Çobaner

“…Increasing the number of transistors to enhance the performance of processors leads to overheating, creating a need for cooling. …”
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Problems of healing chronic wounds by N. M. Babenko, O. B. Litvinova, S. B. Pavlov, M. V. Kumechko, V. V. Komarchuk

“…Choosing the right method of influencing the reparative process, taking into account the leading mechanism of damage repair, becomes very important to ensure the best chance for optimal wound healing.…”
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Research hotspots and trends in lung cancer STAS: a bibliometric and visualization analysis by Xiuhua Peng, Hupo Bian, Hongxing Zhao, Dan Jia, Mei Li, Wenhui Li, Pengliang Xu

“…China, Kadota K, and Fudan University were leading countries, authors, and institutions by publication volume. …”
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Immune checkpoint inhibitors in cancer patients with autoimmune disease: Safety and efficacy by Jiayuan Le, Yuming Sun, Guangtong Deng, Yating Dian, Yanli Xie, Furong Zeng

“…The utilization of immune-checkpoint inhibitors (ICIs) in cancer immunotherapy frequently leads to the occurrence of immune-related adverse events (irAEs), making it generally not recommended for patients with preexisting autoimmune diseases. …”
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The effect of cheese intake on osteoarthritis: a Mendelian randomization study by Song Wen, Zehan Huang, Bin Zhang, Yuqing Huang

“…Introduction Osteoarthritis (OA) is a debilitating chronic disease with a high prevalence, characterized by progressive degeneration of articular cartilage that leads to joint dysfunction, pain, and disability. …”
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Role of CX3CL1/CX3CR1 Signaling Axis Activity in Osteoporosis by Piotr Wojdasiewicz, Pawel Turczyn, Barbara Dobies-Krzesniak, Justyna Frasunska, Beata Tarnacka

“…The present study, based on world literature review, sums and describes convincing evidences of a significant role of the CX3CL1/CX3CR1 axis in processes leading to bone mineral density (BMD) reduction. The CX3CL1/CX3CR1 axis plays a principal role in osteoclast maturation and binding them with immune cells to the surface of the bone tissue. …”
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Comprehensive analysis of histophysiology, transcriptomics and metabolomics in goslings exposed to gossypol acetate: unraveling hepatotoxic mechanisms by Jun Yu, Jun Yu, Haiming Yang, Jian Wang, Zixin Huang, Shi Chen, Hongchang Zhao, Jun Wang, Zhiyue Wang

“…Overall, GA-induced hepatotoxicity involves impaired energy production, disrupted lipid metabolism, and abnormal liver focal adhesion, leading to liver cell dysfunction. These findings highlight the vulnerability of mitochondria and critical metabolic pathways, providing insights into the molecular mechanisms of GA toxicity and guiding future studies on mitigating GA-induced liver damage in goslings.…”
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Inhibition and evasion of neutrophil microbicidal responses by Legionella longbeachae by Hannah E. Hanford, Christopher T. D. Price, Silvia Uriarte, Yousef Abu Kwaik

“…Upon transmission to humans, L. longbeachae invades and replicates within alveolar macrophages, leading to the manifestation of pneumonia. In addition to alveolar macrophages, neutrophils are abundant immune cells acting as the first line of defense against invading pathogens. …”
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Aqueous photocatalytic oxidation of lignin and humic acids with supported <mml:math> <mml:mrow> <mml:msub> <mml:mrow> <mml:mtext>TiO</mml:mtext> </mml:mrow> <...

“…However the addition of <mml:math> <mml:msup> <mml:mtext>Fe</mml:mtext> <mml:mrow> <mml:mn>2</mml:mn><mml:mo>+</mml:mo> </mml:mrow> </mml:msup> </mml:math> ions, up to 0.05 mM, to the lignin solution leads to a dramatic increase, about 25%, in PCO efficiency. …”
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Soil Degradation Evidence Following a Wildfire in Arequipa’s Andean Region, Peru by Lunsden Coaguila, Jorge Mataix-Solera, Sonia Nina, Minerva García-Carmona, Elizabeth T. Salazar

“…The results show that the combined fire and post-fire erosion processes significantly impacted soil properties, leading to a loss of soil organic carbon (SOC), increased bulk density (BD), loss of soil structure and, in the second sampling, a strong reduction in clay content attributable to weak aggregation and erosive processes. …”
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Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer by Snehal Aditya Arvindekar, Sanket Rathod, Prafulla Balkrishna Choudhari, Pradnya Kiran Mane, Aditya Umesh Arvindekar, Suraj Narayan Mali, Bapu Thorat

“…The in silico protocol utilised can be useful in the drug discovery process for development of new leads from structurally diverse set of natural products that are comparable to the drugs used clinically in breast cancer therapy.…”
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Identification of deleterious variants associated with male infertility genes in a cohort of idiopathic hypospermatogenesis patients by Nisha Sharma, Ashutosh Halder, Seema Kaushal, Manoj Kumar, Manish Jain

“…The symptomatic heterozygosity leading to mild spermatogenic failure resulting in hypospermatogenesis points towards a multifactorial etiology of the disease. …”
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Stroke Induces a BDNF-Dependent Improvement in Cognitive Flexibility in Aged Mice by Josh Houlton, Lisa Y. Y. Zhou, Deanna Barwick, Emma K. Gowing, Andrew N. Clarkson

“…Stroke remains a leading cause of disability worldwide. Recently, we have established an animal model of stroke that results in delayed impairment in spatial memory, allowing us to better investigate cognitive deficits. …”
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Chronic abdominal pain. A multidisciplinary approach in gastroenterology and psychiatry by O.Yu. Gubska

“…Antidepressants are the basis of pharmacological therapy for CAPS, with tricyclic antidepressants play a leading role due to their pronounced analgesic effect in low doses, but selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors are also important as the drugs of choice in patients with chronic pain and depressive states. …”
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Combining Host Plant Resistance, Selective Insecticides, and Biological Control Agents for Integrated Management of Tuta absoluta by Peris Wangari Nderitu, Mattias Jonsson, Esther Arunga, Mark Otieno, John Jamleck Muturi, Geoffrey O. Wafula

“…Overreliance on synthetic insecticides in the management of Tuta absoluta has led to pesticide resistance leading to difficulties in managing the pest. In this regard, alternative measures need to be put in place to reduce the effects of this pest. …”
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Assessing safety culture and second victim experience following adverse events among Romanian nurses: a cross-sectional study by Mirabela Ioana Istrate, Alina Ioana Forray, Marius-Ionuț Ungureanu, José Joaquín Mira, Sorana Alexandra Constantinescu, Răzvan Mircea Cherecheș

“…Abstract Background Healthcare adverse events (AEs) significantly impact professionals, often leading to emotional distress and lasting effects. …”
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Influence of Coal Caving Time and Tail Beam Swing Angle on the Evolution of the Coal Gangue Boundary Line during Top Coal Caving by Qingliang Zeng, Yanpeng Zhu, Yang Yang, Zhe Li, Lirong Wan

“…At the same caving time, the position of the coal gangue boundary will be closer to the coal caving outlet, which leads to excessive mixing of coal and gangue. Second, the longer the drawing time, the greater the deformation of the coal gangue boundary, and the easier the coal gangue is mixed, resulting in an increase in the gangue content of the discharged coal. …”
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