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25481
The association between digital technology use and depression among older people in China: a moderated mediation model
Published 2025-02-01“…Promoting social participation through digital technology use is associated with lower depressive symptom scores, and vigorous PAL further strengthens this association, leading to improved mental health.…”
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25482
Study on the potential diagnostic value of metabolomics changes in different biological fluids for aspiration pneumonia
Published 2025-02-01“…While the diagnosis of AP relies on clinical history, swallowing assessments, and imaging, these methods have significant limitations, often leading to underdiagnosis or misdiagnosis. Reliable biomarkers for AP diagnosis are lacking, making early detection and treatment challenging. …”
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25483
Geospatial distribution of Hepatitis E seroprevalence in Nepal, 2021.
Published 2024-12-01“…Limited surveillance capacity and suboptimal access to diagnostics leads to under-reporting of HEV infections in affected countries, including Nepal. …”
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25484
Effect of Intestinal Levodopa-Carbidopa Infusion on Pharyngeal Dysphagia: Results from a Retrospective Pilot Study in Patients with Parkinson’s Disease
Published 2020-01-01“…Pharyngeal dysphagia is a common symptom of Parkinson’s disease (PD) leading to severe complications. PD-related pharyngeal dysphagia (PDrPD) may significantly improve in up to half of patients following acute oral levodopa challenge. …”
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25485
The status of serum 25(OH)D levels is related to breast cancer
Published 2024-01-01“…Aim: Breast cancer is the second most common cancer among women and the leading cause of cancer-related mortality in this population. …”
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25486
Development of HfO₂-Based Solar-Blind SAW UV-C Sensor for Corona Discharge Detection Application
Published 2025-01-01“…Furthermore, the effect of HfO₂ film thickness on the sensor’s response to UV-C exposure was examined in detail, showing that increased thickness leads to a higher frequency shift, thereby enhancing sensitivity. …”
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25487
Currently prescribed drugs in the UK that could upregulate or downregulate ACE2 in COVID-19 disease: a systematic review
Published 2020-09-01“…More studies reported upregulation than downregulation with ACE-I (n=22), ARBs (n=55), insulin (n=8), thiazolidinedione (n=7) aldosterone agonists (n=3), statins (n=5), oestrogens (n=5) calcium channel blockers (n=3) glucagon-like peptide 1 (GLP-1) agonists (n=2) and Non-steroidal anti-inflammatory drugs (NSAIDs) (n=2).Conclusions There is an abundance of the academic literature and media reports on the potential of drugs that could attenuate or exacerbate COVID-19 disease. This is leading to trials of repurposed drugs and uncertainty among patients and clinicians concerning continuation or cessation of prescribed medications. …”
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25488
Constructing adverse outcome pathway for per- and polyfluoroalkyl substances and retinoblastoma based on PI3K-AKT/MAPK signaling pathway
Published 2024-12-01“…The activation of receptor tyrosine kinases (RTKs) served as the molecular initiating event, leading to the activation of key oncogenes such as RAS and AKT, as well as nuclear factor kappa-light chainenhancer of activated B cells (NF-κB), along with the inhibition of the tumor suppressor gene P53. …”
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25489
The Role of Cardiac Resynchronization Therapy in Heart Failure: A Narrative Review
Published 2025-01-01“…ABSTRACT Introduction Structural and functional cardiac defects leading to inadequate tissue oxygenation is known as Heart failure (HF) which is characterized by extensive morbidity and mortality. …”
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25490
Epidemiologic features of non-alcoholic fatty liver disease in Russia
Published 2014-10-01“…Metabolic syndrome and its components have been determined as leading risk factors of this disease, that once again emphasizes significance of interrelation of cardio-vascular diseases and NAFLD. …”
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25491
The Value of P‐Wave Parameters Changes in Predicting Catheter Ablation Outcomes for Paroxysmal Atrial Fibrillation
Published 2025-01-01“…Procedure success was defined by freedom of ECG‐documented AF at 12 months. Digital 12 leads ECGs with 1–50 hertz bandpass filter were monitored before the procedure. …”
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25492
Impact of Cyclosporine A on Cognitive Functions and Neuronal Oxidative Stress, Apoptosis and Inflammatory Markers in Rats
Published 2024-07-01“…In conclusion, CYP-A induces neurotoxicity, leading to oxidative stress, neuroinflammation, apoptosis, and cognitive deficits. …”
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25493
Comparative Study of Chikungunya Only and Chikungunya-Scrub Typhus Coinfection in Children: Findings from a Hospital-Based Observational Study from Central Nepal
Published 2021-01-01“…In children, coinfection with scrub typhus often leads to modification of the clinical profile, complications, and chikungunya outcome.…”
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25494
The role of adenosine monophosphate-activated protein kinase and serum amyloid A proteins in the early diagnosis of neonatal sepsis
Published 2024-09-01“…Neonatal sepsis is a leading cause of mortality among newborns globally, with an incidence of 1 per 1,000 live births. …”
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25495
The immediate alteration of cerebellar Glx/GABA and cerebello-thalamo-cortical connectivity in patients with schizophrenia after cerebellar TMS
Published 2025-02-01“…Additionally, our study shows that cerebellar TMS can increase Glx levels in schizophrenia patients, leading to the normalization of the Glx/GABA ratio, which may contribute to the therapeutic effects of TMS in schizophrenia.…”
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25496
Grafiti: exposición de la religiosidad de las pandillas de San Luis Potosí
Published 2024-08-01“…These graffiti reveal important aspects about both gangs, such as their foreign influence, the rivalry between them, and, most importantly, their close relationship with religious images, like the image of the Virgin of Guadalupe and that of St. Jude Thaddeus. This leads to the conclusion that these gangs, through this religious connection, try to cleanse their criminal actions in order to find a kind of divine acceptance that contrasts with the rejection they receive by the society around them. …”
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25497
Applications of Indocyanine Green in Breast Cancer for Sentinel Lymph Node Mapping: Protocol for a Scoping Review
Published 2025-01-01“… Abstract IntroductionBreast cancer is the leading cause of morbidity and mortality worldwide. …”
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25498
Contribution of Open Access Databases to Intensive Care Medicine Research: Scoping Review
Published 2025-01-01“…Collaborative ventures have enabled the emergence of large open access databases, leading to numerous publications in the field. …”
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25499
Association Between Body Mass Index, Abdominal Obesity and Menopause-Related Symptoms in Postmenopausal Women
Published 2024-12-01“…This is caused by a reduction of the secretion of oestrogen and progesterone, leading to reduced ovarian function. These changes have been attributed to many psychological, vasomotor and urogenital symptoms such as hot flushes, sleep problems, vaginal dryness, anxiety and exhaustion. …”
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25500
Anti-VEGF agents for the treatment of diabetic macular edema
Published 2019-11-01“…Diabetic retinopathy and diabetic macular edema (DME) are the leading causes of vision loss in the working-age population. …”
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