Understanding the exodus: a 15-year retrospective cohort study on the pattern and determinants of migration among Nigerian doctors and dentists by Oghenebrume Wariri, Patience Toyin-Thomas, Itua C.G. Akhirevbulu, Oladapo Oladeinde, Oluchi Omogbai, Philippa Odika, John Osakue, Avwebo Ukueku, Efetobo Orikpete, Chinelo Iwegim, Efe E. Omoyibo, Jermaine Okpere, Uwaila Otakhoigbogie, Ekhosuehi T. Agho, Sunday C. Madubueze, Nnennaya C. Ugoji, Chukwunwike W. Ozegbe, Oti N. Aria, Paul Ikhurionan

“…The top three destination countries were the UK (48.5%, 65/134), Canada (20.9%, 28/134), and the USA (19.4%, 26/134). The leading push factors were insecurity of lives and property (57.8%), concerns about children’s futures (50.3%), and limited career development opportunities (45.9%). …”
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Changes in liver and kidney function, red blood cell count and hemoglobin levels 1 day after ultrasound-guided percutaneous microwave ablation for uterine fibroids by Xiao-Yu Huang, Qin-Sheng Lu, Shao-Ping Wu, Han-Ming Huang, Yong-Fa Zhang

“…The RBC count and HGB levels decreased significantly after UPMWA (p < 0.01).Conclusion Ultrasound-guided percutaneous microwave ablation for uterine fibroids can impose a higher detoxification load on the liver and cause thermal damage to and the destruction of RBCs within local circulation, potentially leading to AKI. Protein levels significantly decreased after UPMWA. …”
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Degradation Kinetics of Ascorbic Acid in Xanthan Gum Solution by Runqi JIA, Yujie TANG, Weiwei HE, Xiaoxiao SONG, Junyi YIN

“…In addition, elevated reaction temperature accelerated the reaction between AA and XG, leading to a degradation rate of AA increased to 45.59% after heating at 90 ℃for 1 h. …”
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Estimating the global cost of vision impairment and its major causes: protocol for a systematic review by Nathan Congdon, Thomas Butt, Peng Tee Khaw, Andrew Bastawrous, Tasanee Braithwaite, Rupert R A Bourne, Matthew J Burton, Serge Resnikoff, Jacqueline Ramke, Kevin Frick, Hugh Taylor, Iris Gordon, Ana Patricia Marques, John Cairns, Justine H Zhang, Hannah B Faal, Iain Jones, Marty Jovic, Allyala Nandakumar

“…The review will include any study published from 1 January 2000 to November 2019 that provides information about costs of illness, burden of disease and/or loss of well-being in participants with VI due to an unspecified cause or due to one of the seven leading causes globally.Two reviewers will independently screen studies and extract relevant data from included studies. …”
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Assessing the Colorectal Cancer Landscape: A Comprehensive Exploration of Future Trends in 216 Countries and Territories from 2021 to 2040 by Meysam Olfatifar, Fariba Rafiei, Amir Sadeghi, Elnaz Ataei, Mohammad Amin Habibi, Mehdi Pezeshgi Modarres, Zohreh Ghalavand, Hamidreza Houri

“…Abstract Background Colorectal cancer (CRC) has become a significant global concern, presenting formidable challenges to healthcare systems and leading to substantial healthcare expenses. This study examines the projected prevalence and trends of CRC worldwide, encompassing 21 regions and 195 nations. …”
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Density-Driven CO₂ Dissolution in Depleted Gas Reservoirs with Bottom Aquifers by Xiaocong Lyu, Fang Cen, Rui Wang, Huiqing Liu, Jing Wang, Junxi Xiao, Xudong Shen

“…Consequently, there is an alleviation of the concentration and density differentials between saturated water and fresh water, resulting in the attenuation of the driving force governing CO₂ diffusion and convection. This leads to a substantial reduction in the rate of CO₂ dissolution, primarily governed by gravity-induced fingering, thereby manifesting as a delay in the onset and decay time of convection, accompanied by a pronounced decrement in the maximum Sherwood number. …”
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Luminescence and scintillation properties of Cs3ZnCl5 and Cs3ZnCl5 (Eu) single crystals by Oleg Yurchenko, Olexandr Rebrov, Victor Cherginets, Ianina Boyarintseva, Tetyana Rebrova, Tamara Ponomarenko, Oleksiy Lebedinskiy, Olga Zelenskaya

“…BGO crystal (Bi4Ge3O12) and the form of the pulse-height spectra for the crystals grown from both melts practically coincide. This leads to the conclusion that the transfer of excitation from the matrix to Eu2+ ions is absent and, according to the photoluminescence studies it can be assumed that Eu2+ exists in the said crystals as inclusions of CsCl:Eu2+ solid solution.…”
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Advantages of using T1-mapping in cardiac magnetic resonance imaging in patients with acromegaly by Alina A. Almaskhanova, Konstantin V. Melkozerov, Elena G. Przhiyalkovskaya, Natalia V. Tarbaeva, Anastasya Y. Korneluk, Raisa S. Kosharnaia, Victor Y. Kalashnikov, Zhanna E. Belaya, Galina A. Mel'nichenko, Natalia G. Mokrysheva

“…To determine the incidence of interstitial myocardial fibrosis (MF) in acromegaly, which leads to the development of cardiac arrhythmias and conduction disorders. …”
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Hospital burden of pneumococcal disease in Spain (2016–2022): A retrospective study by Ruth Gil-Prieto, Valentín Hernandez-Barrera, Patricia Marín-García, Alba González-Escalada, Ángel Gil-de-Miguel

“…Pneumococcal disease is a leading cause of morbidity and mortality worldwide. …”
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Blimp-1 orchestrates macrophage polarization and metabolic homeostasis via purine biosynthesis in sepsis by Wenjuan Peng, Qiushi Qin, Rui Li, Yujia Liu, Lan Li, Yue Zhang, Liuluan Zhu

“…Abstract Sepsis is a life-threatening condition characterized by a dysregulated immune response to infection, leading to systemic inflammation and organ dysfunction. …”
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<i>Weizmannia coagulans</i> BC99 Attenuates Oxidative Stress Induced by Acute Alcoholic Liver Injury via Nrf2/SKN-1 Pathway and Liver Metabolism Regulation by Ying Wu, Cheng Li, Yinyin Gao, Jie Zhang, Yao Dong, Lina Zhao, Yuwan Li, Shaobin Gu

“…In rats, excessive alcohol was predominantly metabolized via the CYP2E1 pathway, leading to severe oxidative stress. However, intervention with BC99 suppressed CYP2E1 expression and enhanced antioxidant enzyme activities through the Nrf2/SKN-1 pathway, thereby alleviating oxidative stress. …”
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Downregulation of hnRNPA1 inhibits hepatocellular carcinoma cell progression by modulating alternative splicing of ZNF207 exon 9 by Qi Ouyang, Qi Ouyang, Wenhui He, Yiping Guo, Lin Li, Ying Mao, Xiang Li, Shuanglin Xiang, Xiang Hu, Jun He

“…IntroductionHepatocellular carcinoma (HCC) is the most prevalent liver cancer and a leading cause of cancer-related deaths worldwide. …”
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Medical Liability of Residents in Taiwan Criminal Court: An Analysis of Closed Malpractice Cases by Kuan-Han Wu, Po-Chun Chuang, Chih-Min Su, Fu-Jen Cheng, Chien-Hung Wu, Fu-Cheng Chen, Yii-Ting Huang

“…By analyzing closed criminal malpractice claims involving resident physicians, we aimed to clarify the characteristics of litigations and examine the litigious errors leading to guilty verdicts. Design. A retrospective descriptive study. …”
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Role of Arg1+ ILC2s and ILCregs in gestational diabetes progression by Zhangyun Gong, Haixing Yi, Jie Zhang, Wan Li, Hao Wang, Peipei Guo, Caihua Li, Anan Pan, Yunxia Cao, Zhimin Lu, Huanhuan Jiang

“…Chronic low-grade inflammation leads to insulin resistance, a major etiological factor in gestational diabetes mellitus (GDM). …”
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Yield and Sensorial and Nutritional Quality of Strawberry (<i>Fragaria</i> × <i>ananassa</i> Duch.) Fruits from Plants Grown Under Different Amounts of Irrigation in Soilless Culti... by Davide Raffaelli, Rohullah Qaderi, Luca Mazzoni, Bruno Mezzetti, Franco Capocasa

“…It is intensified by rising temperatures, leading to greater evaporation and reduced precipitation. …”
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Prenatal bisphenol A and/or diethylhexyl phthalate exposure followed by adult estradiol treatment affects behavior and brain monoamines in female rat offspring by Amrita Kaimal, Jessica M. Hooversmith, Maryam H. Al Mansi, Ariana D. Cherry, Jillian T. Garrity, Philip V. Holmes, Puliyur S. MohanKumar, Puliyur S. MohanKumar, Sheba M. J. MohanKumar, Sheba M. J. MohanKumar

“…Exposure during these times can impact brain development in the offspring, potentially leading to mood disorders in later life. Additionally, fluctuating levels of endogenous estrogens, as seen during pregnancy, or the use of oral contraceptives, can further elevate this risk. …”
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Peroxiredoxin 6 maintains mitochondrial homeostasis and promotes tumor progression through ROS/JNK/p38 MAPK signaling pathway in multiple myeloma by Dandan Gao, Yang Lv, Fei Hong, Dong Wu, Ting Wang, Gongzhizi Gao, Zujie Lin, Ruoyu Yang, Jinsong Hu, Aili He, Pengyu Zhang

“…In addition, oxidative stress decreased mitochondrial membrane potential (MMP), reduced gene expression levels of oxidative phosphorylation (OXPHOS), and increased in the density of mitochondrial crumpling, leading to mitochondrial structural abnormalities and dysfunction. …”
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Evaluation of intranasal TLR2/6 agonist INNA-051: safety, tolerability and proof of pharmacology by Francesca A. Mercuri, Scott White, Hayley A. McQuilten, Charlotte Lemech, Stephan Mynhardt, Rana Hari, Ping Zhang, Nicole Kruger, Grant McLachlan, Bruce E. Miller, Nicholas P. West, Ruth Tal-Singer, Christophe Demaison

“…The objectives of the present study were to understand the potential of prophylactic treatment with a TLR2/6 agonist as an enhancer of innate immunity pathways leading to accelerated respiratory virus clearance from the upper airways. …”
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Knowledge and Attitude about Basic Life Support and Emergency Medical Services amongst Healthcare Interns in University Hospitals: A Cross-Sectional Study by Shahabe A. Saquib, Hassan M. Al-Harthi, Anas A. Khoshhal, Adel A. Shaher, Abdulsalam B. Al-Shammari, AbdulAhad Khan, Tahani A. Al-Qahtani, Imran Khalid

“…Road traffic accident and sudden cardiac arrest are one of the most leading causes of death in KSA. Basic life support (BLS) is lifesaving intervention as a premedical facility. …”
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First Results from the JWST Early Release Science Program Q3D: The Fast Outflow in a Red Quasar at z = 0.44 by Weizhe Liu, Sylvain Veilleux, Swetha Sankar, David S. N. Rupke, Nadia L. Zakamska, Dominika Wylezalek, Andrey Vayner, Caroline Bertemes, Yuzo Ishikawa, Yu-Ching Chen, Jenny E. Greene, Timothy Heckman, Guilin Liu, Hsiao-Wen Chen, Dieter Lutz, Sean D. Johnson, Nicole P. H. Nesvadba, Patrick Ogle, Nadiia Diachenko, Andy D. Goulding, Kevin N. Hainline, Fred Hamann, Hui Xian Grace Lim, Nora Lützgendorf, Vincenzo Mainieri, Ryan McCrory, Grey Murphree, Lu Shen, Eckhard Sturm, Lillian Whitesell

“…The higher spatial resolution of our new observation leads to more reliable measurements of outflow kinematics. …”
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