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24981
Measurements and Modeling of the Responses of VLF Transmitter Signals to X‐Class Solar Flares at the Great Wall Station in Antarctica
Published 2023-04-01“…Abstract Solar flares can severely disturb the Earth's ionosphere, leading to changes of atmospheric chemistry and degradation of Global Navigation Satellite System (GNSS) signals. …”
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24982
Chemokine family significance and prognostic value in colorectal cancer
Published 2025-01-01“…BackgroundColorectal cancer (CRC) poses a substantial global health concern, exhibits inconspicuous early symptoms, and is typically diagnosed at advanced stages leading to unfavorable outcomes. The intricate tumor microenvironment plays a crucial role in CRC development and progression, where chemokines contribute significantly. …”
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24983
The Role of Caspase-4 and NLRP1 in MCF7 Cell Pyroptosis Induced by hUCMSC-Secreted Factors
Published 2020-01-01“…Mesenchymal stem cells (MSCs) are being widely investigated for the development of novel therapeutic approaches for different cancers, including breast cancer, the leading form of cancer in women. Our previous study showed that the factors secreted by human umbilical cord MSCs (hUCMSCs) induced pyroptosis in the breast cancer cell line MCF7 and our RNA sequencing studies revealed an increase in the expression of the pyroptosis-related gene caspase-4 (CASP4) and nucleotide-binding, leucine-rich repeat pyrin domain-containing protein 1 (NLRP1) in pyroptotic MCF7 cells. …”
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24984
Epidemiology of Pediatric Traumatic Brain Injury at Sylvanus Olympio University Hospital of Lomé in Togo
Published 2019-01-01“…Severe pediatric traumatic brain injury (pTBI) is a leading cause of disability and death in children worldwide. …”
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24985
Deficiency of purinergic P2Y2 receptor impairs the recovery after renal ischemia-reperfusion injury and accelerates renal fibrosis and tubular senescence in mice
Published 2024-12-01“…Renal ischemia-reperfusion (IR) induces oxidative stress and inflammatory responses leading to severe tissue damage, where incomplete or maladaptive repair accelerates renal fibrosis and aging. …”
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24986
Emerging Trends and New Developments in Transient Elastography: A Bibliometric and Cocitation Analysis from 1999 to 2017
Published 2019-01-01“…(n=21) and France (n=43) was the leading country. The most productive journal was Journal of Hepatology (n=20). …”
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24987
First Detection of <i>Wolbachia</i> in Namibian Bird Ectoparasites (Acariformes: Syringophilidae) with a Description of New Quill Mite Species
Published 2024-12-01“…In arthropods, it typically acts as a reproductive parasite, leading to various phenotypic effects such as cytoplasmic incompatibility, parthenogenesis, feminization, or male-killing. …”
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24988
PD-L1 monoclonal antibody alleviated MI injury of left ventricular function via modulating CD47/SHP2/SIRPα/SYK/FcγR signalings in tumor associated macrophages
Published 2025-01-01“…Treatment with a STING inhibitor significantly reduced the cGAMP effect, leading to improved left ventricular function in mice with MI. …”
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24989
Cell Wall Protein 2 as a Vaccine Candidate Protects Mice Against <i>Clostridioides difficile</i> Infection
Published 2024-12-01“…Standard treatment options for <i>C. difficile</i> infection (CDI) involve a limited selection of antibiotics that are not fully effective, leading to high recurrence rates. Vaccination presents a promising strategy for preventing both CDI and its recurrence. …”
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24990
Exploring the impact of insufficient thermal ablation on hepatocellular carcinoma: NDST2 overexpression mechanism and its role in facilitating growth and invasion of residual cance...
Published 2024-12-01“…Additionally, NDST2 was knocked down in heat stress-induced HCC cells, and the effects of NDST2 on these cells were verified using Cell Counting Kit-8 assays, scratch assays, and Transwell assays.Results NDST2 expression levels are elevated in HCC, leading to a decrease in overall survival rates of HCC patients. …”
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24991
Effect of ocean acidification on the oxygen consumption of the sea urchins Paracentrotus lividus (Lamarck, 1816) and Arbacia lixula (Linnaeus, 1758) living in CO2 natural gradients
Published 2025-02-01“…Ocean acidification (OA) stands out as one of the main threats to marine ecosystems. OA leads to a reduction in the availability of carbonate ions, which are essential for marine calcifiers such as echinoderms. …”
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24992
An Integrated Electricity–Gas–Heat Energy System Based on the Synergy of Long- and Short-Term Energy Storage
Published 2024-12-01“…The example shows that the configuration of the electrical–thermal hybrid energy storage system proposed in this paper leads to a significant improvement in the economy, with an increase in annual profit of CNY 3.78 million, or 22.96%. …”
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24993
Design of a novel Cu-Cr-X alloy with high strength and high electrical conductivity based on mechanical learning
Published 2025-02-01“…The outstanding performance enhancement and rapid prediction of process scopes leads us to recognise that the great potential of multi-objective machine-learning-aid design in the complex composition and process problems.…”
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24994
Designing a glass nanoshell on barium titanium trioxide to suppress nanocrystal growth during sintering for fine-grain dielectric ceramics
Published 2025-03-01“…However, BT70, with a larger specific surface area, higher reactivity, and lower crystallinity, was more prone to hydrolyze in the sol-gel process, leading to the formation of a new phase after sintering, Ba2TiSi2O8, which adversely affected both the sintering behavior and dielectric properties. …”
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24995
Tgfbr1 regulates lateral plate mesoderm and endoderm reorganization during the trunk to tail transition
Published 2025-01-01“…The vascular remodeling involving the dorsal aorta and the umbilical artery leading to the connection between embryonic and extraembryonic circulation was also affected in the Tgfbr1 mutant embryos. …”
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24996
Neural Correlates of Irritability and Potential Moderating Effects of Inhibitory Control
Published 2025-03-01“…Conclusions: Exploratory findings indicate that reduced between-network connectivity may underlie difficulty regulating negative emotions, leading to greater irritability.…”
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24997
Immune imbalance in the pre-ovulatory follicular microenvironment of overweight and obese women during IVF
Published 2025-02-01“…Conclusion Overweight and obesity can disrupt immune hemostasis in the pre-ovulatory follicular microenvironment, potentially leading to adverse effects on assisted reproductive outcomes.…”
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24998
Application Analysis of Intelligent Robot Inspection System at Offshore Step-up Substation
Published 2025-01-01“…As offshore wind farms continue to expand into deeper and farther waters, the safety risks, operation and maintenance costs, inspection efficiency and other problems brought by the manual inspection mode become even more prominent, leading to the increasing demand for intelligent inspection of offshore wind farms. …”
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24999
Polymorphic variants of the <i>hOGG1, APEX1, XPD, SOD2</i>, and <i>CAT</i> genes involved in DNA repair processes and antioxidant defense and their association with breast cancer r...
Published 2024-07-01“…Breast cancer is one of the leading causes of mortality among women. The most frequently encountered tumors are luminal tumors. …”
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25000
Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance
Published 2025-01-01“…This regulatory function can be disrupted by Factor H autoantibodies (FHAA), which then leads to diseases such as atypical hemolytic uremic syndrome (aHUS) and C3 Glomerulopathy (C3G). …”
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