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24541
Costs of outpatient services at selected primary healthcare centers in Bangladesh: A cross-sectional study.
Published 2025-01-01“…<h4>Conclusion</h4>Our study found significant gaps between prescribed and provided medicines at UzHCs, leading to higher OOPE for patients. The current healthcare resource allocation strategy does not consider the outpatient load and healthcare demand at PHC facilities, which further exacerbates this gap. …”
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24542
Zebularine Promotes Hepatic Differentiation of Rabbit Bone Marrow Mesenchymal Stem Cells by Interfering with p38 MAPK Signaling
Published 2018-01-01“…Zebularine at concentrations of 10, 20, and 50 μM could not affect cell viability after 48 h. Zebularine treatment leads to an inhibition of DNMT activity and increase of hepatic-specific proteins alpha-fetoprotein and albumin in BMMSCs in vitro; zebularine addition also induced expression of urea production of and ICG metabolism. p38 signal was activated in BMMSCs simulated with HGF; inhibition of p38 facilitated the synthesis of DNMT1 and albumin in cells. …”
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24543
Two-year follow-up of gait and postural control following initiation of recombinant human tripeptidyl intracerebroventricular enzyme replacement therapy in two atypical CLN2 patien...
Published 2025-01-01“…Abstract Neuronal ceroid lipofuscinosis type 2 (CLN2) is a rapidly progressive neurodegenerative disorder leading to premature mortality. Ambulatory CLN2 patients typically receive standard of care treatment through biweekly intracerebroventricular (ICV) enzyme replacement therapy (ERT) involving recombinant human tripeptidyl peptidase 1, known as cerliponase alfa (Brineura®, Biomarin Pharmaceuticals). …”
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24544
Evaluation of community behavior regarding the risk of plastic micro-pollution on the environment health
Published 2024-01-01“…BACKGROUND AND OBJECTIVES: Plastic pollution is increasing globally along with the growing consumption patterns of the global community, leading to practicality (social behavior). The primary contributors to pollution are single-use plastic (SUP) items and inadequate waste management techniques. …”
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24545
Deconstrucţia canonului literar în critica actuală română şi sârbă
Published 2010-12-01“…It is the case of numerous Romanian writers to have had a better reception abroad than in România. This leads to the conclusion that critics like Negrici, while trying to demistify the canons of Romanian literature, involve in a new process of myth-formation, which is not in favour of Romanian literature.…”
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24546
Characterization of YdgH: a mediator of beta-lactam susceptibility in Enterobacterales
Published 2025-01-01“…In a previous screen for novel genetic mediators affecting beta-lactam susceptibility, we discovered that deletion of ydgH, a conserved gene of unknown function, leads to increased resistance to beta-lactams, as well as increased susceptibility to detergent compounds. …”
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24547
Integrated microRNA and mRNA signatures associated with overall survival in epithelial ovarian cancer.
Published 2021-01-01“…Ovarian cancer (OC), the eighth-leading cause of cancer-related death among females worldwide, is mainly represented by epithelial OC (EOC) that can be further subdivided into four subtypes: serous (75%), endometrioid (10%), clear cell (10%), and mucinous (3%). …”
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24548
Disruption of Gut Microbiota and Associated Fecal Metabolites in Collagen-Induced Arthritis Mice During the Early Stage
Published 2025-02-01“…Especially, SCFAs were strongly associated with Bifidobacterium, Alistipes, Ruminococcus, Anaerotruncus, and Allobaculum.Conclusion: These findings suggest that collagen immunization leads to disruption of gut microbiome and induces changes of fecal metabolites in mice, which may play a key role in early development of RA in CIA mice.Keywords: gut microbiota, fecal metabolites, short-chain fatty acids, preclinical stage, collagen-induced arthritis…”
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24549
Optimizing the gelation, structure, and thermal stability of alkali-induced duck egg white gels with calcium chloride
Published 2025-01-01“…However, this method often leads to gel liquefaction and structural instability. …”
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24550
Synthesis and application of zinc oxide nanoparticles in Pieris brassicae larvae as a possible pesticide effect
Published 2024-10-01“…Pieris brassicae is commonly known as the cabbage moth and is a species known to be invasive, thereby causing serious damage to vegetables and subsequently leading to total crop loss. Formulations of nanopesticides can provide unique characteristics such as size and shape, in addition to having integrated properties in a single material, making them efficient in pest management and protection against diseases in a single material; it can be applied in small volumes, with a greater precision, lower input costs, and a potential reduction in environmental contamination. …”
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24551
Compressive Characteristics and Fracture Simulation of Cerasus Humilis Fruit
Published 2025-01-01“…During the harvesting process of Cerasus humilis, the fruits are susceptible to compression and impacts from the combing teeth, leading to internal damage to the pulp and rupture of the peel. …”
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24552
Organization of the regional cancer service to improve the detection of malignant new formations during the COVID-19 pandemic
Published 2021-06-01“…Results. MagO region, leading in the rate of morbidity and mortality from malignant neoplasms in the Far Eastern Federal District: incidence of malignant neoplasms for 2009-2019 increased by 23 %. …”
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24553
The quality of early breast cancer diagnosis in urban women by doctors of adult polyclinics
Published 2019-12-01“…In oncology, one of the leading places belongs to breast cancer. This problem is particularly significant in the current situation, when the issue of reproductive health of the female population is acute lyuped in connection with the unfavourable demographic trends in our country. …”
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24554
A comparative analysis and survival analysis of open versus minimally invasive radical antegrade modular pancreatosplenectomy for pancreatic cancer: a systematic review and meta-an...
Published 2025-01-01“…BackgroundPancreatic ductal adenocarcinoma (PDAC) is a major public health concern, ranking as the fourth leading cause of cancer-related mortality in the United States. …”
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24555
Multimorbidity in Atherosclerotic Cardiovascular Disease and Its Associations With Adverse Cardiovascular Events and Healthcare Costs: A Real-World Evidence Study
Published 2024-03-01“…**Background:** Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of mortality and disability in the United States and worldwide. …”
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24556
Chemical Control of the Invasive Weed <i>Trianthema portulacastrum</i>: Nethouse Studies
Published 2024-12-01“…The results of pre-emergence herbicide screening showed that Fomesafen, Terbutryne, Flurochloridon, Sulfosulfuron, Cyrosulfamid + Izoxaflutole, and Dimethenamid were the most effective herbicides, leading to complete eradication of <i>T. portulacastrum</i> plants. …”
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24557
Pengenalan Jalan Berlubang Berbasis Vision Menggunakan Pyramid Histogram Of Oriented Gradients
Published 2023-07-01“…Abstract Potholes on roads can damage vehicles and endanger drivers, potentially leading to accidents. Preventative management of potholes is crucial for driver safety and efficient traffic flow. …”
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24558
Glycemic Profile and Clinical Treatment in Patients with Diabetes Mellitus-Tuberculosis: An Update Scoping Review
Published 2025-02-01“…Raya Bandung Sumedang KM.21 Hegarmanah, Jatinangor, Sumedang, West Java, 45363, Indonesia, Tel +62895604502223, Email nursiswati@unpad.ac.idBackground: Type 2 diabetes mellitus (T2DM), characterized by chronic hyperglycemia, leads to a decreased immune system and increased susceptibility to infections, such as tuberculosis (TB). …”
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24559
Advancements in Public First Responder Programs for Out-of-Hospital Cardiac Arrest: An Updated Literature Review
Published 2025-01-01“…Out-of-hospital cardiac arrest (OHCA) is a leading cause of death worldwide, with a low survival rate of around 7% globally. …”
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24560
Effectiveness of a 5-day adapted swim instruction program for children with disabilities
Published 2025-01-01“…BackgroundDrowning is a leading cause of death for children. Some populations of children with disabilities, such as children with autism, experience a health disparity in drowning when compared to peers without disabilities.ObjectiveThis study presents a secondary data analysis of the response to intervention for a 5-day adapted swim instruction program (iCan Swim) for children with disabilities (n = 164 participants) ages 3–18 years.MethodsThis secondary data analysis assessed the effectiveness of the swim intervention on changes in swim skill level from Day 1 to Day 5. …”
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