Flow Cytometry Evaluation of Blood-Cell-Bound Surface FVIII in Hemophilia A and Thrombosis by Anjud Al-Mohannadi, Reem Mohammed Yahia, Hani Bibawi, Che-Ann Lachica, Watfa Ahmed, Igor Pavlovski, Giusy Gentilcore, Elkhansa Elbukhari Elgaali, Anila Ejaz, Areeg Ahmed, Mohammed Elanbari, Zainab Awada, Mohammed J. Al-Kubaisi, Muhammad Elnaggar, Ayman Saleh, Chiara Cugno, Sara Deola

“…Hemophilia A (HA) is associated with FVIII coagulation insufficiency or inactivity leading to excessive bleeding. Elevated FVIII, on the contrary, is associated with thrombophilia, thrombosis, myocardial infarctions, and stroke. …”
Get full text

A Low-Cost Layered Double Hydroxide (LDH) Based Amperometric Sensor for the Detection of Isoproturon in Water Using Carbon Paste Modified Electrode by Herve Leclerc Tcheumi, Aude Peggy Kameni Wendji, Ignas Kenfack Tonle, Emmanuel Ngameni

“…After optimization, a linear calibration curve was obtained in the concentration range from 2 × 10−8 to 1.8 × 10−7 M, leading to a detection limit of 1 × 10−9 M (S/N = 3). …”
Get full text

Analysis of Inflammatory Mediator Profiles in Sepsis Patients Reveals That Extracellular Histones Are Strongly Elevated in Nonsurvivors by Tanja Eichhorn, Ingrid Linsberger, Lucia Lauková, Carla Tripisciano, Birgit Fendl, René Weiss, Franz König, Gerhard Valicek, Georg Miestinger, Christoph Hörmann, Viktoria Weber

“…The timely recognition of sepsis and the prediction of its clinical course are challenging due to the complex molecular mechanisms leading to organ failure and to the heterogeneity of sepsis patients. …”
Get full text

Blood Glucose Lowering Efficacy of Strawberry Extracts Rich in Ellagitannins with Different Degree of Polymerization in Rats by Juśkiewicz Jerzy, Jurgonski Adam, Kołodziejczyk Krzysztof, Kosmala Monika, Milala Joanna, Zduńczyk Zenon, Fotschki Bartosz, Żary-Sikorska Ewa

“…The results clearly showed that the separate mechanisms (glucose transport across the intestine, intestinal mucosal disaccharidases inhibition activity, pancreatic α-amylase inhibitory activity) leading to decreased postprandial glycaemia upon dietary administration of strawberry ellagitannins largely depended on their chemical structure, i.e. degree of polymerization.…”
Get full text

Sporothrix brasiliensis Gp70 is a cell wall protein required for adhesion, proper interaction with innate immune cells, and virulence by Leonardo Padró-Villegas, Manuela Gómez-Gaviria, Iván Martínez-Duncker, Luz A. López-Ramírez, José A. Martínez-Álvarez, Gustavo A. Niño-Vega, Héctor M. Mora-Montes

“…Sporothrix brasiliensis is one of the leading etiological agents of sporotrichosis, a cutaneous and subcutaneous mycosis worldwide distributed. …”
Get full text

Trending applications of Phase Change Materials in sustainable thermal engineering: An up-to-date review by Matteo Morciano, Matteo Fasano, Eliodoro Chiavazzo, Luigi Mongibello

“…The on-going search for increasingly sustainable and efficient thermal energy management across a wide range of sectors leads to continuous exploration of innovative solutions. …”
Get full text

From Technical Prerequisites to Improved Care: Distributed Edge AI for Tomographic Imaging by Bilgehan Akdemir, Hafiz Faheem Shahid, Mikael A. K. Brix, Juho Laakkola, Johirul Islam, Tanesh Kumar, Jarmo Reponen, Miika T. Nieminen, Erkki Harjula

“…Recent years have seen a surge in AI-driven medical image processing, leading to significant improvements in diagnostic performance. …”
Get full text

Accelerated development of multi-component alloys in discrete design space using Bayesian multi-objective optimisation by Osman Mamun, Markus Bause, Bhuiyan Shameem Mahmood Ebna Hai

“…This study evaluates several leading multiobjective BO acquisition functions–namely, parallel expected hypervolume improvement (qEHVI), noisy qEHVI, parallel parEGO, and parallel noisy parEGO (qNparEGO)–in optimizing the physical properties of multi-component alloys. …”
Get full text

Strategic SWOT analysis of the University of Nigeria Teaching Hospital using Modified Delphi Technique: implications for strengthening national and regional health systems by Cyril Chukwudi Dim, Chinyere Ojiugo Mbachu, Nympha Onyinye Enebe, Wilson Chukwukasi Kassy, Johnpaul Ejikeme Nnagbo, Ikechukwu Emmanuel Obi, Nkiruka Pauline Onodugo, Nwamaka Ngozika Lasebikan, Obinna Donatus Onodugo

“…By identifying its internal strengths and weaknesses and external opportunities and threats, the hospital can thus formulate effective strategies to enhance its performance and maintain its position as a leading healthcare institution.…”
Get full text

The REpeated ASSEssment of SurvivorS in intracerebral haemorrhage: protocol for a multicentre, prospective observational study by Daniel Woo, Richard Thompson, Carl D Langefeld, Nichol McBee, Daniel Hanley, Matthew L Flaherty, Lauren Sansing, Karen Lane, Lee A Gilkerson, Achala Vagal, Nathan Walborn, Wendy Ziai, Noeleen Ostapkovich, Kevin Triene, Timothy David Howard

“…If successful, the REASSESS study could demonstrate that reduction of ICH volume is a critical target to reduce the risk of progressive cognitive decline, establish targets for residual haematoma volume reduction and determine if greater residual haematoma volume leads to a long-term inflammatory state.Ethics and dissemination Approval of this study was obtained from the Johns Hopkins University Institutional Review Board (IRB00311985). …”
Get full text

Utilization of refuse-derived fuel in industrial applications: Insights from Uttar Pradesh, India by Utsav Sharma, Dayanand Sharma, Amit Kumar, Tushar Bansal, Ankit Agarwal, Shudhanshu Kumar, Abid Hussian, Hesam Kamyab, Moinul Haq

“…Urbanization and population growth in India have quickened, leading to an annual generation of around 62 million tonnes of municipal solid waste (MSW). …”
Get full text

Performance evaluation of the Qiagen BK virus ASR on the NeuMoDx system by Amorce Lima, Luciano Soares, Caroline Simmons, Laura Rowe, Dominic Uy, Deanna Becker, Suzane Silbert

“…Compared to the SOC, the Qiagen BKV ASR had a more automated workflow, with less hands-on time, leading to quicker turnaround time. Conclusion: The Qiagen BKV ASR is specific, sensitive, and accurate in quantifying BKV in plasma and urine specimens on the fully automated NeuMoDx™ 96 System.…”
Get full text

Evaluation of mental disorder related to colposcopy procedure during the COVID period: A cross-sectional study by Ilaria Bochicchio, Martina Catalano, Giovanni Deiana, Giandomenico Roviello, Pasquale Marino, Fabrizia Calenda, Alessandro R Lettini, Francesca Sanseverino

“…Background: The Coronavirus Disease (COVID-19) has had a significant impact on healthcare organizations, leading to a reduction in screening. The pandemic period has caused important psychological repercussions in the most fragile patients. …”
Get full text

Mapping the Dream: Designing Optimal E-Bike Routes in Valparaíso, Chile, Using a Multicriteria Analysis and an Experimental Study by Vicente Aprigliano, Catalina Toro, Gonzalo Rojas, Iván Bastías, Marcus Cardoso, Tálita Santos, Marcelino Aurélio Vieira da Silva, Emilio Bustos, Ualison Rébula de Oliveira, Sebastian Seriani

“…Addressing these aspects could position Valparaíso as a leading example of sustainable urban mobility for cities facing comparable challenges.…”
Get full text

Higher AVCO2 and Lactate Gradient Combined with SOFA Score as a Mortality Predictor during the 6-Hours of Resuscitation of Septic Shock by Morteza Talebi Doluee, Sahar Azam Ghasemzadeh, Ahmad Bagheri Moghadam, Zahra Abbasishaye, Davood Soroosh, Elnaz Vafadar Moradi

“… Background: Sepsis is a severe and life-threatening condition leading to widespread inflammation and organ dysfunction. …”
Get full text

A novel cytoprotective organ perfusion platform for reconstructing homeostasis of DCD liver while alleviating IRI injury by Tingting Lan, Mingxing Yu, Tao Ming, Hong Wang, Juan Deng, Shuhan Cheng, Zhongyang Shen, Deling Kong

“…However, the continuous extrusion forming with the rigid stationary shaft of the peristaltic pumps can damage cells, leading to metabolic disorders and eventual dysfunction of transplanted organs. …”
Get full text

Propylene glycol-based deep eutectic solvent as an alternative to Ethaline for electrometallurgy by Bertoloni, Calogera, Mba Ekomo, Vitalys, Villemejeanne, Benoît, Lemoine, Charly, Duwald, Romain, Billy, Emmanuel, Mendil-Jakani, Hakima,  Legeai, Sophie

“…Because changing the hydrogen bond donor leads to a modification in the DES bulk properties, the first part of this work deals with the determination of PG-based DESs’ density, viscosity, and conductivity, which are properties of interest for electrochemical processes. …”
Get full text

Monitoring of agricultural progress in rice-wheat rotation area based on UAV RGB images by Jianliang Wang, Jianliang Wang, Chen Chen, Senpeng Huang, Senpeng Huang, Hui Wang, Yuanyuan Zhao, Yuanyuan Zhao, Jiacheng Wang, Jiacheng Wang, Zhaosheng Yao, Zhaosheng Yao, Chengming Sun, Chengming Sun, Tao Liu, Tao Liu

“…However, the current monitoring methods mainly rely on manual recording and observation, leading to low monitoring efficiency. This study addresses the challenges of monitoring agricultural progress and the time-consuming and labor-intensive nature of the monitoring process. …”
Get full text

Hydrogen sulfide attenuates disturbed flow-induced vascular remodeling by inhibiting LDHB-mediated autophagic flux by Xia Wang, Xiying Huang, Yongya Zhang, Huanhuan Huo, Guo Zhou, Linghong Shen, Long Li, Ben He

“…Furthermore, LDHB interacted with vacuolar-type proton ATPase catalytic subunit A (ATP6V1A), leading to lysosomal acidification, a process that was attenuated by NaHS treatment. …”
Get full text

Spatial and Temporal Evolution of Different‐Scale Ionospheric Irregularities in Central and East Siberia During the 27–28 May 2017 Geomagnetic Storm by V. B. Ovodenko, M. V. Klimenko, I. E. Zakharenkova, A. V. Oinats, D. S. Kotova, A. V. Nikolaev, I. V. Tyutin, D. D. Rogov, K. G. Ratovsky, D. V. Chugunin, P. A. Budnikov, J. C. Coxon, B. J. Anderson, A. A. Chernyshov

“…An increase and equatorward displacement of Region 1 (R1)/Region 2 (R2) FACs leads to appearance and equatorward expansion of ionospheric irregularities. …”
Get full text