Autophagy-Enhancing Properties of <i>Hedyotis diffusa</i> Extracts in HaCaT Keratinocytes: Potential as an Anti-Photoaging Cosmetic Ingredient by Qiwen Zheng, Xiangji Jin, Trang Thi Minh Nguyen, Eun-Ji Yi, Se-Jig Park, Gyeong-Seon Yi, Su-Jin Yang, Tae-Hoo Yi

“…The decline in autophagy disrupts homeostasis in skin cells, leading to oxidative stress, energy deficiency, and inflammation—all key contributors to skin photoaging. …”
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Refined Modeling of Geoeffective Fast Halo CMEs During Solar Cycle 24 by E. Yordanova, M. Temmer, M. Dumbović, C. Scolini, E. Paouris, A. L. E. Werner, A. P. Dimmock, L. Sorriso‐Valvo

“…In addition, we performed multi‐CME runs to simulate potential interactions. This leads, to even larger uncertainties in the forecast. …”
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Enhanced compressive strength and in vitro degradation of porous pectin/ calcium phosphate cement scaffolds by freeze casting without sintered by Hao Zhang, Yufei Tang, Xuan Zhou, Qian Liang, Yani Sun, Bo Zhang, Kang Zhao, Zixiang Wu

“…The apatite phase with low crystallinity can be obtained following the hydration reaction of the non-sintered calcium phosphate bone cement (CPC) scaffolds. However, this leads to the formation of a weak alkaline environment during degradation, ultimately resulting in unsustainable degradation. …”
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Effects of Active Video Games Combined with Conventional Physical Therapy on Perceived Functionality in Older Adults with Knee or Hip Osteoarthritis: A Randomized Controlled Trial by Francisco Guede-Rojas, Cristhian Mendoza, Jorge Fuentes-Contreras, Cristian Alvarez, Bárbara Agurto Tarbes, Javiera Karina Muñoz-Gutiérrez, Adolfo Soto-Martínez, Claudio Carvajal-Parodi

“…Background: Osteoarthritis (OA) leads to functional decline in older adults. This study aimed to evaluate the effectiveness of active video games (AVGs) as a complement to conventional physical therapy (CPT) in improving functional disability. …”
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Design and Characteristics of a Single-Story Building Model Incorporating Waste by Mohamed Darwish, Mohamed Elnakeb, Marina Moawad, Marwan Mohamed Shawki, Ehab Abdelhamid, Donia Eldwib, Mohamed Nagib Abouzeid, Maram Saudy, Safwan Khedr, Khaled Nassar

“…That study showed that the roofs made of Structural Insulated Panels (SIPs) using Wood-Plastic Composite (WPC) facings when used with hollow-block cement block walls have shown enduring cost efficiency and improved thermal insulation, leading to diminished energy usage, life-cycle expenses, and carbon emissions. …”
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Factors Affecting Treatment Adherence Among Patients with Tuberculosis in Indonesia: Literature Review by Fahrul Islam, Haeranah Ahmad, Nurbaya, Masnaeni Ahmad, Ansar, Kadar Ramadhan, Muhammad Syukri, Syafran Arrazy, Agung Aji Perdana, Deborah Siregar, Nining Ade Ningsih, Ikes Dwi Astuti, St. Kadijah Hamid, Asrul Hamonangan Pasaribu

“…Introduction: Tuberculosis (TB) is the leading cause of death from infectious diseases in the world and Indonesia is the second largest contributor to TB cases after India. …”
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Understanding the Spectrum of Mild Clinical Outcomes and Novel Findings in Arterial Tortuosity Syndrome Among Qatari Patients: Implications of SLC2A10 Mutation by Muhammed Riyas K. Rahmath, Haytham Ibrahim, Muhammad Faiyaz-Ul-Haque, Zafar Nawaz, Ahmad Zitoun, Ahmed Hussein, Ahmed Sadek, Ayman El-Menyar, Reema Kamal, Hassan Al-Thani, Gulab Sher

“…<b>Results</b>: The study revealed that the NM_030777.4(SLC2A10):c.243C>G (p.Ser81Arg) mutation in SLC2A10 leads to mild outcomes of no mortality and less morbidity. …”
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Accelerated and precise skin cancer detection through an enhanced machine learning pipeline for improved diagnostic accuracy by SM Masfequier Rahman Swapno, S.M. Nuruzzaman Nobel, P.K. Meena, V.P. Meena, Jitendra Bahadur, Abhishek Appaji

“…Unrepaired DNA damage in skin cells causes mutations leading to skin cancer, a highly aggressive malignancy. …”
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The impact on productivity costs of reducing unemployment in patients with advanced breast cancer: A model estimation based on a Portuguese nationwide observational study by Leonor Vasconcelos de Matos, Margarida Borges, Ana Teresa Oliveira, Carolina Bulhosa, Luís Silva Miguel, Tiago Fidalgo de Freitas, Renato Cunha, Ana Duarte Mendes, Ana Júlia Arede, Cristiana Marques, Diogo Alpuim Costa, Jorge Alves Correia, Margarida Brito, Mário Fontes e Sousa, Teresa Guimarães, Fatima Cardoso

“…A subsidized part-time employment regimen, despite increased government costs, would allow a reduction in productivity costs, leading to a positive balance of 2,431,329€ over the same period. …”
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Fibrin Glue Enhances Adipose-Derived Stromal Cell Cytokine Secretion and Survival Conferring Accelerated Diabetic Wound Healing by Ursula Hopfner, Matthias M. Aitzetmueller, Philipp Neßbach, Michael S. Hu, Hans-Guenther Machens, Zeshaan N. Maan, Dominik Duscher

“…Results. Fibrin glue seeding leads to a significantly enhanced secretion of key cytokines (SDF-1, bFGF, and MMP-2) of human ASCs in vitro. …”
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Isolation, genetic, and biological characterization of human adenovirus type 55 positive isolates from Wuhan, China by Jing Xie, Yan Wang, Huan Li, Bingxiu Tan, Zhengying Yu, Lizhong Li, Wei Zhang, Hongbin Song, Leili Jia

“…Infections by HAdV-55, one of the important pathogens leading to respiratory tract infections, often develop into pneumonia and are frequently associated with outbreaks in military camps and schools. …”
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Ddx21 mutant peptide is an effective neoantigen in prophylactic lung cancer vaccines and activates long-term anti-tumor immunity by Zhe Zhang, Yimeng Xia, Yimeng Xia, Zhihong Wang, Yaxing Sun, Dan Pu, Yijia He, Ruixian Liu, Yanru Zhang, Yan Liu, Junzhi Yu, Shiyang Ning, Baisui Feng, Yaohe Wang, Na Wang

“…IntroductionLung cancer is the leading cause of cancer-related death worldwide, and its morbidity and mortality are increasing. …”
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Investigating the impact of acceptance and commitment therapy for mental healthcare professionals: the effect on patients´ self-stigmatization, a pilot study by Kim L. Helmus, Kim L. Helmus, Kim L. Helmus, Marilon van Doorn, Marilon van Doorn, Mariken B. de Koning, Mariken B. de Koning, Mariken B. de Koning, Inez Myin-Germeys, Frederike N. Schirmbeck, Frederike N. Schirmbeck, Therese A. M. J. van Amelsvoort, Dorien H. Nieman, Dorien H. Nieman, Monique W. M. Jaspers, Monique W. M. Jaspers, Arne Popma, Arne Popma, Lieuwe de Haan, Lieuwe de Haan

“…On the contrary, no effect was found on the subscales ‘awareness’, ‘agreement’ and ‘hurt-self’.ConclusionPreliminary results suggest that a brief ACT training for MHCP might heighten their awareness and contribute to reduction of their stigmatizing attitudes and behavior, leading to less application of self-stigmatizing beliefs in their patients.…”
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Role of Vitamin D and E as Antioxidants Against Cerebral Endothelial Dysfunction: An In Vivo Study in White Rats (Rattus norvegicus) Sepsis Model by Fauzan Fajri, Sukmawan Fajar, Denny Irmawati Hasan, Herlina Dimiati, Eka Yunita Amna, Nora Sovira, Anidar Anidar, Mulya Safri, Aris Gunawan

“…Sepsis is a life-threatening condition caused by the body's response to an infection, leading to organ dysfunction. A antioxidants can help neutralize harmful free radicals that cause cellular and tissue damage through oxidative stress. …”
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MiMeJF: Application of Coupled Matrix and Tensor Factorization (CMTF) for Enhanced Microbiome-Metabolome Multi-Omic Analysis by Zheyuan Ou, Xi Fu, Dan Norbäck, Ruqin Lin, Jikai Wen, Yu Sun

“…However, widely used multi-omic data analyses often employ a stepwise mining approach, failing to harness the full potential of multi-omic datasets and leading to reduced detection accuracy. Synergistic analysis incorporating microbiome/metabolome data are essential for deeper understanding. …”
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Effect of Load Vector Orientation on Uniaxial Compressive Strength of 3D Photoresin by Evgenii Kozhevnikov, Mikhail Turbakov, Evgenii Riabokon, Zakhar Ivanov, Andrei Golosov, Arina Panteleeva, Yan Savitsky

“…In contrast, the lower part of the layer, with a higher degree of polymerization, leads to brittle behavior in the samples.…”
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Comparing Campylobacter jejuni to three other enteric pathogens in OligoMM12 mice reveals pathogen-specific host and microbiota responses by Mathias K.-M. Herzog, Audrey Peters, Nizar Shayya, Monica Cazzaniga, Kardokh Kaka Bra, Trisha Arora, Manja Barthel, Ersin Gül, Luca Maurer, Patrick Kiefer, Philipp Christen, Katharina Endhardt, Julia A. Vorholt, Gad Frankel, Markus M. Heimesaat, Stefan Bereswill, Cormac G. M. Gahan, Marcus J. Claesson, Xavier Domingo-Almenara, Wolf-Dietrich Hardt

“…., Listeria monocytogenes and enteropathogenic/enterohemorrhagic Escherichia coli (EPEC/EHEC) are leading causes of food-borne illness worldwide. Citrobacter rodentium has been used to model EPEC and EHEC infection in mice. …”
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Case report: Accidental aconitine poisoning caused by the inappropriate use of a type of Chinese patent medicine by Ruikai Shang, Ruikai Shang, Hongyu Liu, Qiaoxin Tian, Qiaoxin Tian, Yuru Liu, Xiangdong Jian, Xiangdong Jian, Qilu Li

“…However, improper use and overdose can easily cause acute poisoning, leading to malignant arrhythmias, cardiogenic shock, and even death.MethodsThis study retrospectively analyzed the clinical data of eight patients who were treated in our hospital from June 2023 to February 2024 after taking compound schizonepeta fumigation lotion by mistake.Case presentationWe report 8 cases of patients who took compound schizonepeta fumigation lotion by mistake. …”
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Hypoxia-induced CTCF mediates alternative splicing via coupling chromatin looping and RNA Pol II pause to promote EMT in breast cancer by Parik Kakani, Shruti Ganesh Dhamdhere, Deepak Pant, Rushikesh Joshi, Sachin Mishra, Anchala Pandey, Dimple Notani, Sanjeev Shukla

“…This further regulates the CTCF-mediated RNA polymerase II pause at COL5A1exon64A, leading to its inclusion in promoting the EMT under hypoxia. …”
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Early and delayed STAT1-dependent responses drive local trained immunity of macrophages in the spleen by Aryeh Solomon, Noa Bossel Ben-Moshe, Dotan Hoffman, Sébastien Trzebanski, Dror Yehezkel, Leia Vainman, Mihai G Netea, Roi Avraham

“…Trained immunity (TI) is the process wherein innate immune cells gain functional memory upon exposure to specific ligands or pathogens, leading to augmented inflammatory responses and pathogen clearance upon secondary exposure. …”
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