Thermal deformation compensation scheme to the sub-nanometre level of a piezoelectric offset mirror for MHz repetition rate free-electron laser by Baoning Sun, Qinming Li, Chuan Yang, Kai Hu, Zhongmin Xu, Xiaohao Dong, Weiqing Zhang, Xueming Yang

“…Such deformation degrades the characteristics of the reflected photon beam, leading to focal spot aberrations and wavefront distortions that fail to meet experimental requirements. …”
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Unveiling shadows: A data-driven insight on depression among Bangladeshi university students by Sanjib Kumar Sen, Md. Shifatul Ahsan Apurba, Anika Priodorshinee Mrittika, Md. Tawhid Anwar, A.B.M. Alim Al Islam, Jannatun Noor

“…Each of these factors can play a significant role in leading someone towards depression, with their impact varying from person to person. …”
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Free convection investigation for a Casson-based Cu−H2O nanofluid in semi parabolic enclosure with corrugated cylinder by Rafel H. Hameed, Rana Ali Hussein, Qusay H. Al-Salami, Mohammed Azeez Alomari, Ahmed M. Hassan, Farah Q.A. Alyousuf, Faris Alqurashi, Mujtaba A. Flayyih

“…These findings provide valuable insights for designing more efficient thermal management systems in applications such as electronics cooling, solar thermal collectors, and heat exchangers, potentially leading to improved energy efficiency and performance in various industrial and technological sectors.…”
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Tracing the Origin of Oxide Inclusions in Vacuum Arc Remelted Steel Ingots Using Trace Element Profiles and Strontium Isotope Ratios by Christoph Walkner, Gulnaz Mukhametzianova, Stefan Wagner, Jörg C. Korp, Andreas Graf, Johanna Irrgeher, Thomas C. Meisel, Thomas Prohaska

“…The combination of the data allowed the drawing of conclusions about the processes leading to the formation of these inclusions. For both specimens, very similar results were obtained, indicating a common mechanism of formation. …”
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The temporal evolution of HCHO and changes in atmospheric composition in the southeast of the United Kingdom by Balendra V.S. Chauhan, Kirsty L. Smallbone, Maureen Berg, Kevin P. Wyche

“…Elevated temperatures accelerate VOC oxidation reactions, leading to increased HCHO formation. The study also finds a significant correlation (81 %) between summertime tropospheric O3 and air temperature. …”
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Protocol for a systematic review and individual participant data meta-analysis for risk factors for lung cancer in individuals with lung nodules identified by low-dose CT screening by Matthew Callister, Harry J de Koning, Robert C Rintoul, Carolyn Horst, Arjun Nair, John K Field, Christine D Berg, Samantha Quaife, Rhian Gabe, Stephen Duffy, Sam Janes, Philip AJ Crosbie, Mark M Hammer, Panos Alexandris, Michael PA Davies

“…Background Worldwide, lung cancer (LC) is the second most frequent cancer and the leading cause of cancer related mortality. Low-dose CT (LDCT) screening reduced LC mortality by 20–24% in randomised trials of high-risk populations. …”
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ERK5 Contributes to VEGF Alteration in Diabetic Retinopathy by Yuexiu Wu, Yufeng Zuo, Rana Chakrabarti, Biao Feng, Shali Chen, Subrata Chakrabarti

“…Several signaling mechanisms are activated secondary to hyperglycemia in diabetes, leading to activation of vasoactive factors. We investigated a novel pathway, namely extracellular signal regulated kinase 5 (ERK5) mediated signaling, in modulating glucose-induced vascular endothelial growth factor (VEGF) expression. …”
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The assessment of change in human heat stress risk in Brazil projected by the CMIP6 models by Laila K Gohar, Dan Bernie, Damian Wilson, Kate Willett, Richard Betts

“…Thresholds in the environmental conditions leading to heat stress in humans are projected to be exceeded for long periods of the year across large parts of the country. …”
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Spatiotemporal dynamics of early oogenesis in pigs by Wei Ge, Yi-Lin Niu, Yu-Kang Li, Li Li, Han Wang, Wen-Wen Li, Tian Qiao, Yan-Ni Feng, Yu-Qing Feng, Jing Liu, Jun-Jie Wang, Xiao-Feng Sun, Shun-Feng Cheng, Lan Li, Wei Shen

“…Abstract Background In humans and other mammals, the process of oogenesis initiates asynchronously in specific ovarian regions, leading to the localization of dormant and growing follicles in the cortex and medulla, respectively; however, the current understanding of this process remains insufficient. …”
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Problematic internet use and its relationship with eating disorders by Claudia Ruiz-Centeno, Raquel Cueto-Galán, Raquel Cueto-Galán, Raquel Cueto-Galán, Jose Miguel Pena-Andreu, Andrés Fontalba-Navas, Andrés Fontalba-Navas, Andrés Fontalba-Navas

“…It has been demonstrated that self-esteem in adolescents and young adults can be affected by social media use, leading to body dissatisfaction that may result in increased use of these platforms with access to pro-anorexia and pro-bulimia content, which can contribute to the development of these disorders. …”
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Professional experiences on use of the mental health act in ethnically diverse populations: a photovoice study by Roisin Mooney, Paul McCrone, Rose McCabe, Kamaldeep Bhui, Brian Brown, Colin King, Andrew Molodynski, Nusrat Husain, Jacqueline Sin, Karen Newbigging, Michael Larkin, Neil Caton, Raghu Raghavan, Doreen Joseph, Anthony Zigmond, Michelle Yeung, Julie Carr, Phuong Hua, Frank Keating, Tara Morey, Claire Dempsey, Rahul Battacharya, Nuwan Dissanyake, Rochelle Ramkisson, Laura Dixon, Kopal Tandon, Gary Roberts, Paul Illingworth, Jo White, Karen Persaud, Sayeeda Basharat, Tripti Kandia, Sandra Griffiths, Michael Molete

“…We undertook a thematic analysis.Results Ineffective communications between inpatient and community services, insufficient staff capacity, a lack of continuity of care and language and cultural constraints meant MHA assessments were lacking information, leading to elevated perceptions of risk. Practitioners felt helpless at times of staff shortages and often felt CAT could have been prevented. …”
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Influences of different components on viscosities of CaO-MgO-Al2O3-SiO2 melts by Zhang G.H., Chou K.C., Lv X.Y.

“…The addition of Al2O3 leads to a complex variation of viscosity. In different composition ranges, viscosity may exhibit different variation tendencies as changing the relative contents of CaO and MgO while keeping contents of other components constant. …”
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Prediction of Colorectal Cancer Risk Using a Genetic Risk Score: The Korean Cancer Prevention Study-II (KCPS-II) by Jaeseong Jo, Chung Mo Nam, Jae Woong Sull, Ji Eun Yun, Sang Yeun Kim, Sun Ju Lee, Yoon Nam Kim, Eun Jung Park, Heejin Kimm, Sun Ha Jee

“…Colorectal cancer (CRC) is among the leading causes of cancer deaths and can be caused by environmental factors as well as genetic factors. …”
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The role of the C5a-C5aR pathway in iron metabolism and gastric cancer progression by Qinxue Ni, Hong Yang, Hang Rao, Liyong Zhang, Mengyuan Xiong, Xiao Han, Boshao Deng, Lulu Wang, Jian Chen, Yan Shi

“…Gastric cancer continues to be a leading global health concern, with current therapeutic approaches requiring significant improvement. …”
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Proximity-based solutions for optimizing autism spectrum disorder treatment: integrating clinical and process data for personalized care by Annarita Vignapiano, Annarita Vignapiano, Francesco Monaco, Francesco Monaco, Stefania Landi, Luca Steardo, Carlo Mancuso, Claudio Pagano, Gianvito Petrillo, Alessandra Marenna, Martina Piacente, Stefano Leo, Carminia Marina Ingenito, Rossella Bonifacio, Benedetta Di Gruttola, Marco Solmi, Marco Solmi, Marco Solmi, Marco Solmi, Maria Pontillo, Giorgio Di Lorenzo, Giorgio Di Lorenzo, Alessio Fasano, Alessio Fasano, Alessio Fasano, Giulio Corrivetti, Giulio Corrivetti

“…This project will improve access to care, personalize treatments for better outcomes, shorten wait times, boost patient involvement, and raise ASD awareness, leading to better resource allocation. This project marks a transformative shift toward data-driven, patient-centred ASD care in Italy. …”
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miR-34a Regulates Multidrug Resistance via Positively Modulating OAZ2 Signaling in Colon Cancer Cells by Yong Li, Ping Gong, Ji-xue Hou, Wei Huang, Xiao-ping Ma, Yu-li Wang, Jing Li, Xiao-bin Cui, Na Li

“…Consequently, suppression of the expression of miR-34a/OAZ2 signaling by chemotherapeutic agents significantly enhanced the activation of MDR-associated ATP-binding cassette (ABC) transporters and antiapoptosis pathways, thus leading to MDR development in CCa cells. Collectively, our combined analysis reveals a critical role of miR-34a/OAZ2 cascade in conferring a proper cellular response to CCa chemotherapy.…”
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Quantitative Analysis of Energy Storage Demand in Northeast China Using Gaussian Mixture Clustering Model by Yiwen Yao, Yu Shi, Jing Wang, Zifang Zhang, Xin Xu, Xinhong Wang, Dingheng Wang, Zilai Ou, Zhe Ma

“…However, a clear quantitative assessment of the region’s energy storage needs is lacking, leading to weak grid stability and limited growth potential. …”
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Increased Intra-Abdominal Pressure as One of the Links in the Pathogenesis of Secondary Diffuse Purulent Peritonitis by D. V. Cherdantsev, O. V. Ovchinnikova, Yu. G. Trofimovich, I. G. Noskov, O. V. Pervova, A. A. Kovalenko

“…This condition is characterized by increased pressure in two or more anatomical areas, which leads to decreased blood flow and subsequent tissue hypoxia. …”
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Prosaposin – A plausible biomarker in head and neck squamous cell carcinoma by Avradeep Datta, Rajandeep Kaur, Anshika Chauhan, Geeta Singh Boora, Himanshu Garg, Debajyoti Chatterjee, Jaimanti Bakshi, Sushmita Ghoshal, Arnab Pal

“…Objectives: Head and Neck Squamous Cell Carcinoma (HNSCC) is one of the leading cancers in developing countries with very high morbidity and mortality. …”
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Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy by Timothy J Abreo, Emma C Thompson, Anuraag Madabushi, Kristen L Park, Heun Soh, Nissi Varghese, Carlos G Vanoye, Kristen Springer, Jim Johnson, Scotty Sims, Zhigang Ji, Ana G Chavez, Miranda J Jankovic, Bereket Habte, Aamir R Zuberi, Cathleen M Lutz, Zhao Wang, Vaishnav Krishnan, Lisa Dudler, Stephanie Einsele-Scholz, Jeffrey L Noebels, Alfred L George, Atul Maheshwari, Anastasios Tzingounis, Edward C Cooper

“…Kcnq2G256W/+ mice have epilepsy leading to premature deaths. Hippocampal CA1 pyramidal cells from G256W/+ brain slices showed hyperexcitability. …”
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