Costs of Potential Medication Wastage Due to Switching Treatment Among People With Multiple Sclerosis by Darin T. Okuda, Achal Patel, Robert Schuldt, Ibraheem Abioye, Nicole G. Bonine

“…People with multiple sclerosis (PwMS) commonly switch disease-modifying therapies (DMTs), leading to medication wastage and substantial costs for insurers and patients. …”
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Numerical investigating the impact of fluid properties and oscillation frequency on micro mixer efficiency by Sajad Ghanbari, Mohammad Sefid, Mohammad Ali Sabbaghi

“…As the difference in viscosity and density between the two fluids increases, the level of mixing decreases, such that an increase in the logarithmic viscosity ratio up to R = 2 results in a 257.66 % reduction in mixing, and an increase in the density ratio up to S = 3 leads to a 170.08 % reduction in mixing efficiency. …”
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Autoimmune hepatitis under the COVID-19 veil: an analysis of the nature of potential associations by Chaojie Yu, Wenrui Wang, Qian Zhang, Zhenjing Jin

“…In this review, we analyse the clinical-immunological characteristics, risks associated with severe disease progression, and prognosis for AIH patients infected with SARS-CoV-2; discuss the detrimental effects exerted by SARS-CoV-2 on hepatic function; summarise the mechanisms and attributes leading to new-onset AIH; as well as provide insights into how vaccination may interfere with autoimmunity processes. …”
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A COMBINATION OF CHEEK FLAP, CARTILAGE INSERTION, AND FAT TRANSFER ON POST-TRAUMA LOWER EYELID ECTROPION RECONSTRUCTION by Ulfa Elfiah, Dicky Primadika Aprinova

“… • This method effectively addresses the challenges of cicatricial ectropion caused by injuries or burns, leading to improved, durable, and cost-effective outcomes in restoring eyelid function and volume. …”
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Developing and Activated T Cell Survival Depends on Differential Signaling Pathways to Regulate Anti-Apoptotic Bcl-xL by Ruiqing Wang, Huimin Xie, Zhaofeng Huang, Weirong Shang, Zuoming Sun

“…The anti-apoptotic protein Bcl-xL is the ultimate effector regulating the survival of CD4+CD8+ thymocytes subject to the selection process, and the deletion of Bcl-xL leads to premature apoptosis of thymocytes prior to the completion of the developmental process. …”
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Loss of pelagic fish and zooplankton density associated with subglacial upwelling in high Arctic estuaries may be mitigated by benthic habitat expansion following tidewater glacier... by Victor Gonzalez Triginer, Arunima Sen, Maxime Geoffroy, Børge Damsgård

“…As tidewater glaciers retreat into land, this subglacial circulation will disappear and sedimentation from terrestrial runoff will increase, leading to a decrease in pelagic productivity with a decline in the abundance of fish and zooplankton. …”
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The Growth and Yield of Rice (Oryza sativa L.) with Organic and Inorganic Fertilizer Application by Cellulolytic Microbes in Peat by Atrisina Allamah, Hapsoh Hapsoh, Wawan Wawan, Isna Rahma Dini

“…Limitations of productive land causing agricultural extension leads on marginal land. Peatlands are one type of land including the criteria for marginal land. …”
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Siponimod supports remyelination in the non-supportive environment by Johann Krüger, Newshan Behrangi, David Schliep, Leo Heinig, Elise Vankriekelsvenne, Nicole Wigger, Markus Kipp

“…Abstract Inflammatory demyelination, a hallmark of multiple sclerosis (MS) lesions, leads to functional impairments and progressive axonal loss over time. …”
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Influence of organism stimulation with bacterial lipopolysaccharide on nitric oxide production and metabolism in rat heart on the background of metabolic syndrome by O. Ye. Akimov, A. O. Mykytenko, V. O. Kostenko

“…Combination of metabolic syndrome and stimulation of organism with bacterial lipopolysaccharide leads to prevalence of peroxynitrite formation during increased nitric oxide production NO-synthase-dependent and nitrate-nitrite-NO pathways in rat heart.…”
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Model Predictive Current Control with Asymmetric Stacked Multilevel Inverter and LCL-Filter Based STATCOM by Mostafa Q. Kasim, Raaed Faleh Hassan

“…One of the essential features of this inverter that distinguishes it from the conventional types is that it achieves the required voltage levels with fewer switching devices, leading to simplifying the control process. Moreover, the work includes using a Finite Control Set Model Predictive Current Control (FCS-MPCC) to control the proposed structure. …”
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Characteristics and Driving Mechanism of Soil Organic Carbon Content in Farmland of Beijing Plain: Implication for the Fate of Engineered Polymers in Soil by Lanlan Zhang, Zhen Li, Shiwen Zhang, Shasha Xia, Hongguang Zou, Yuanfang Huang

“…SOC content increases as organic fertilizer input rises, and an extra unit (15 kg·ha−1) of organic fertilizer input leads to an increase of 0.057 g·kg−1 in SOC content. …”
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Damage control resuscitation: how it’s done and where we can improve. A view of the Brazilian reality according to trauma professionals by MARCELO AUGUSTO FONTENELLE RIBEIRO JUNIOR, LETICIA STEFANI PACHECO, JUAN CARLOS DUCHESNE, JOSE GUSTAVO PARREIRA, SHAHIN MOHSENI

“…ABSTRACT Introduction: Hemorrhage is the leading cause of preventable deaths in trauma patients, resulting in 1.5 million deaths annually worldwide. …”
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Digitalization of the Workflow for Drone-Assisted Inspection and Automated Assessment of Industrial Buildings for Effective Maintenance Management by Jorge Torres-Barriuso, Natalia Lasarte, Ignacio Piñero, Eduardo Roji, Peru Elguezabal

“…This paper researches an innovative digitalized process for the inspection and diagnosis of industrial buildings, which leads to categorizing and prioritizing maintenance actions in an objective and cost-effective way from the inspection data. …”
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Occurrence of severe cognitive impairment in elderly individuals with poor glycemic control Vs elderly individuals with good glycemic control or no DM: a case control study” by Basma Salman, Fatima Jehangir, Aroosa Jahan, Saira Aslam, Nadra Ansari

“… ABSTRACT: Background: There is substantiatial corroboration that diabetes (both T1DM and T2DM) plays an essential role in predisposition to cognitive decline thus leading to dementia in both human and animal studies. (1,2,3). …”
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The Sequence of Prostaglandin-Endoperoxide Synthase 2 Gene in Women with Cervicitis by Maha A. Ahlial, Nazar Sh. Mohammed, Maysara S. Khalaf

“…Prostaglandin endo peroxide synthase2 (Cyclooxygenase-2) is a key enzyme in prostaglandin synthesis, which is coded by the PTGS2 gene, and recognized as the master switch that activates the inflammatory response; its induction leads to the biosynthesis of prostaglandins. The current study aims to determine the CA125, CA 19.9, and, CA 15.3 markers level and their relationship with the COX-2 gene. …”
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Comparison of Bimatoprost 0.03% and Brimonidine 0.2% in Managing Intraocular Pressure Elevation Following Nd:YAG Laser Capsulotomy for Posterior Capsule Opacification by Tulika Gupta, Rupali Kashyap, Shikhar Ganjoo

“…It is a dynamic process caused by the migration and proliferation of residual lens epithelial cells on the posterior capsule, leading to visual impairment. The standard treatment for PCO is neodymium: yttrium–aluminum–garnet (Nd: YAG) laser capsulotomy. …”
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A Novel Network for Choroidal Segmentation Based on Enhanced Boundary Information by Wenbo Huang, Chaofan Qu, Yang Yan

“…A custom loss function, specifically designed to replace the conventional Mean Squared Error (MSE) loss, is utilized to optimize network parameters, leading to further improvements in segmentation performance. …”
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Understanding the Relationship Between Cerebrovascular Disease and the Gut Microbiome by William Roth, Elaine Lo, Orlando De Leon, Sajid Suriya, Farima Fakhri, James R. Brorson, Sean Polster, Tareq Kass‐Hout, Shyam Prabhakaran, James E. Siegler

“…Moreover, the metabolism of certain substrates found in animal products (notably l‐carnitine and choline) and of refined sugars by these microorganisms leads to buildup of circulating metabolites with known links to atherogenesis, platelet activation, atrial fibrillation, and other adverse vascular outcomes. …”
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Qualitative financial modelling in fractal dimensions by Rami Ahmad El-Nabulsi, Waranont Anukool

“…These fractional models are expected since the Black–Scholes equation is derived using Ito’s lemma from stochastic calculus, where fractional derivatives play a leading role. Hence, a fractional stochastic model that includes the basic Black–Scholes model as a special case is expected. …”
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Gender-specific secular trends and related factors of high perceived stress level among Korean older adults: a nation-wide serial cross-sectional study by Eunjeong Choi, Hyun-Ju Seo, Kye Ha Kim, Sun-Young Jung

“…Abstract Background Aging is associated with various physical, functional, and social losses, leading to stress, which affects mental health and overall quality of life. …”
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