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23441
Design of pH-Responsive Nanomaterials Based on the Tumor Microenvironment
Published 2025-01-01“…Yunheng Liu,1,* Longqing Si,1,* Yuxuan Jiang,1,* Shaojing Jiang,2 Xiaokang Zhang,1 Song Li,1 Jing Chen,1 Jinghui Hu2 1School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, People’s Republic of China; 2Yantai Engineering Research Center for Digital Technology of Stomatology, Characteristic Laboratories of Colleges and Universities in Shandong Province for Digital Stomatology, Institute of Stomatology, Binzhou Medical University, Yantai, 264003, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Chen, School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, People’s Republic of China, Email chenjingbyyxy@163.com Jinghui Hu, Yantai Engineering Research Center for Digital Technology of Stomatology, Characteristic Laboratories of Colleges and Universities in Shandong Province for Digital Stomatology, Institute of Stomatology, Binzhou Medical University, Yantai, 264003, People’s Republic of China, Email bykfhjh@163.comAbstract: The metabolic activity of tumor cells leads to the acidification of the surrounding microenvironment, which provides new strategies for the application of nanotechnology in cancer therapy. …”
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23442
PREDICTION OF THE INCIDENCE OF PROSTATE CANCER IN THE URAL ECONOMIC REGION OF THE RUSSIAN FEDERATION
Published 2016-06-01“…In recent years, the development of medical technology has led to the expansion of the arsenal of diagnostic and therapeutic opportunities in prostate cancer leading to the emergence of alternative choice of activities in the preparation of individual treatment plan of the patient with newly diagnosed. …”
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23443
Knowledge and attitudes towards cervical cancer and screening among migrant women: a qualitative study in Portugal
Published 2024-12-01“…Objective To explore the perceptions of migrant women, healthcare professionals and community workers regarding migrant women’s knowledge and attitudes about cervical cancer (CC) and screening and how these influence cervical cancer screening (CCS) uptake.Design Qualitative study with seven focus groups, using a semistructured guide.Setting Five focus groups were conducted online and two in community associations in Lisbon, Portugal.Participants This study included 23 migrant women, 12 healthcare professionals and 10 community workers.Results A lack of knowledge and negative attitudes towards screening among migrants were discussed as important factors leading to a lower CCS uptake. For participants, many migrant women are unaware of the disease and CCS. …”
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23444
The reproductive function of women with infertility after suffering COVID-19 infection
Published 2023-06-01“…Determined changes in reproductive function may be directly or indirectly related to the "long-COVID" consequences, namely, a high level of stress, anxiety and depression, pernicious habits, general fatigability that leads to a sedentary lifestyle, sleep disturbances, the developing or exacerbation of somatic pathologies, among which stand out metabolic disorders and pathology of the liver and gastrointestinal tract. …”
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23445
Analysis of mortality factors in ICU patients with sepsis and septic shock: a retrospective study
Published 2025-01-01“…Abstract Background Sepsis and septic shock are critical conditions that pose significant challenges in intensive care units (ICUs), characterized by a dysregulated host response to infection, leading to organ dysfunction and high mortality rates. …”
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23446
Multispectral Polarization State Analyzer of Scanning Polarimeter ScanPol
Published 2020-01-01“…The errors of azimuth mount of Wollaston prisms ≤2 arcmin in ScanPol leads to error of degree of linear polarization ≤0.0012.…”
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23447
POSITIVISM AND ITS ADVERSARIES: BRADLEY, COLLINGWOOD, NIETZSCHE AND HEIDEGGER
Published 1998-01-01“…At the same time he believes that positivism excels all previous philosophies and is a step leading to his own philosophy. The relation of Heidegger to positivism is ambivalent as well. …”
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23448
Exploring the use of solid fuels for cooking and household air pollution in informal settlements through photovoice: The Fuel to Pot study in Ndirande (Malawi) and Mukuru (Kenya).
Published 2024-01-01“…<h4>Introduction</h4>Worldwide, 2.4 billion people rely on solid fuels such as wood or charcoal for cooking, leading to approximately 3.2 million deaths per year from illnesses attributable to household air pollution. …”
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23449
Measuring overall functional diversity by aggregating its multiple facets: Functional richness, biomass evenness, trait evenness and dispersion
Published 2025-01-01“…Abstract Human activities induce environmental changes, which can affect individuals' traits thereby leading to changes in functional diversity and finally in ecosystem functioning. …”
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23450
Social Support Theory for Predicting Stress, Anxiety, and Job Burnout of Healthcare Workers in the Post-pandemic COVID-19
Published 2025-01-01“…Background: The COVID-19 pandemic created substantial mental health challenges for healthcare workers, leading to elevated levels of stress, anxiety, and burnout. …”
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23451
Comprehensive characterization of platelet function in dogs with hyperadrenocorticism
Published 2025-02-01“… Hyperadrenocorticism (HAC) leads to a hypercoagulable state and contributes to the risk of thromboembolic disease. …”
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23452
SEARCHING FOR THE TRUE SELF: THE WAY OF NONDUAL WISDOM
Published 2017-12-01“…People become existentially absorbed in the world - the changeful world of artists and children, the world where everyone and everything undergo transformations. Meditation leads to the new horizons, to the awareness of infinity and diversity of life. …”
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23453
The Regulation Effect of α7nAChRs and M1AChRs on Inflammation and Immunity in Sepsis
Published 2021-01-01“…It coordinates not only the sympathetic system and vagus system but also the autonomic nervous system and neuroendocrine system to regulate inflammation and immunity; α7nAChRs are widely expressed in immune cells, neurons, and muscle cells; the activation of α7nAChRs can suppress local and systemic inflammation; the expression of α7nAChRs represents the acute or chronic inflammatory state to a certain extent; M1AChRs are mainly expressed in the advanced centers of the brain and regulate systemic inflammation; neuroinflammation of the MVZ, hypothalamus, and forebrain induced by sepsis not only leads to their dysfunctions but also underlies the regulatory dysfunction on systemic inflammation and immunity. …”
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23454
The Effects of Coronavirus Disease-19 Pandemic on Tuberculosis Treatment Uptake and Outcomes in the Fako Division of Cameroon
Published 2024-12-01“…Background: Tuberculosis (TB) caused by Mycobacterium tuberculosis is an infectious disease affecting mainly the lungs and persists as the leading cause of death worldwide. With the emergence of coronavirus disease-19 (COVID-19) pandemic, the management and outcome of TB has been greatly affected because of the global shift in attention. …”
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23455
Etiology of Tendency Toward Using Cannabis: A Qualitative Study of the Lived Experiences of Teenager’s Consumers
Published 2024-12-01“…Main categories included cognitive distortion regarding the effects of cannabis, low mood frustration, lack of a specific work plan, having an unstable personality, unawareness of the harmful nature of cannabis, usage to cope with emotional problems, usage to cope with parental conflicts, peer influence on usage, justification of usage by modeling after prominent figures, and accessibility (easy access) leading to increased usage. Conclusion. Exploring the experiences and views of adolescents who consume cannabis in intrapersonal, interpersonal, and extrapersonal domains provided more knowledge about different indicators of cannabis consumption among teenagers. …”
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23456
Ekoantropologia antyhumanistyczna. Przypadek Johna Nicholasa Graya
Published 2015-12-01“…Gray’s anti-humanistic eco-anthropology leads us in the end to a sombre, pessimistic vision of the post-humankind that a highly probable destiny is mass destruction if human beings do not come to their senses in time becoming the straw subjects.…”
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23457
Vaginal bleeding during pregnancy: a retrospective cohort study assessing maternal and perinatal outcomes
Published 2025-02-01“…As vaginal bleeding may compromise newborn health outcomes, for example, leading to low birth weight and neonatal intensive care unit (NICU) hospitalizations, it is imperative to understand the etiology of the bleed and effectively manage the patient’s condition. …”
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23458
Acute kidney injury and outcomes in hospitalized children with autoimmune rheumatic disease
Published 2025-02-01“…Abstract Background Autoimmune rheumatic diseases (ARDs) in children can negatively impact renal function, potentially leading to acute kidney injury (AKI). This study compares the prevalence of AKI and other adverse in-hospital outcomes among hospitalized children with ARDs. …”
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23459
Oral Findings, Salivary Copper, Magnesium, and Leptin in Type II Diabetic Patients in Relation to Oral Candida Species
Published 2024-01-01“…Type 2 diabetes is a condition in which the body becomes resistant to the effects of insulin, leading to reduced insulin production in the pancreas. …”
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23460
Repurposing antiviral drugs targeting the PARP-1 and HER2 pathways with multifaceted impacts through integrated network analysis and molecular mechanics
Published 2025-06-01“…Molecular docking studies were performed to evaluate drug-receptor interactions, leading to the selection of promising candidates: Fostemsavir, Efavirenz, Doravirine, and Didanosine for HER2, and Efavirenz, Lopinavir, Fostemsavir, and Elvitegravir for PARP-1. …”
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