Revealing excitation-inhibition imbalance in Alzheimer’s disease using multiscale neural model inversion of resting-state functional MRI by Guoshi Li, Li-Ming Hsu, Ye Wu, Andrea C. Bozoki, Yen-Yu Ian Shih, Pew-Thian Yap

“…Also, we find that local inhibitory connections are more significantly impaired than excitatory ones and the strengths of most connections are reduced in MCI and AD, leading to gradual decoupling of neural populations. …”
Get full text

Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori. by Md Nahian, Md Rasel Khan, Fabiha Rahman, Hossain Mohammed Reza, Imren Bayil, Tanjum Ahmed Nodee, Tabassum Basher, Mostafizur Rahaman Sany, Rabeya Najnin Munmun, S M Ariful Habib, Lincon Mazumder, Mrityunjoy Acharjee

“…Helicobacter pylori is a gram-negative bacterium that persistently infects the human stomach, leading to peptic ulcers, gastritis, and an increased risk of gastric cancer. …”
Get full text

FD-YOLO: A YOLO Network Optimized for Fall Detection by Hoseong Hwang, Donghyun Kim, Hochul Kim

“…Falls represent a serious public health issue, ranking as the second leading cause of death from unintentional injuries, following traffic accidents. …”
Get full text

The Malthusian parameter and $R_0$ for heterogeneous populations in periodic environments by Hisashi Inaba

“…Our arguments depend on the uniform primitivity of positive evolutionary system, which leads the weak ergodicity and the existence of exponential solution in periodic environments. …”
Get full text

Associating Field Actors in the Observation of Visitor Flows and Recreational Activities in Mountain Regions: Lessons Drawn from two Collaborative Projects in France and Switzerlan... by Christophe Clivaz, Marc Langenbach, Olivier Obin, Alexandre Savioz

“…First of all, this concerns the rise in the rain-snow limit and the increasing scarcity of snow (Gonseth, 2013), leading ski lift companies to invest heavily in the production of artificial snow in order to sustain the activities of skiing and snowboarding (Abegg, 2011; Clivaz et al., 2015). …”
Get full text

Experimental Testing and Numerical Simulation of Recycled Concrete Aggregate in a Concrete Mix by Bini Neupane, Kameshwar Sahani, Shyam Sundar Khadka

“…Additionally, the RCA increased the flexural strength, with R25 leading with a 5% increase and R50 following with a 1.66% increase at 28 days of testing. …”
Get full text

Roxadustat improves diabetic myocardial injury by upregulating HIF-1α/UCP2 against oxidative stress by Tingting Fang, Congcong Ma, Bingyun Yang, Meiyu Zhao, Luning Sun, Ningning Zheng

“…Hyperglycemia induces oxidative stress, compromising mitochondria energy metabolism disturbances, leading to cardiomyocyte hypoxia and dysregulation of hypoxia-inducible factor-1α (HIF-1α), thereby exacerbating diabetic myocardial injury. …”
Get full text

Stiffness of a fire-damaged reinforced concrete column during unloading after high-intensity horizontal impact by A. G. Tamrazyan, V. I. Chernik

“…The low-cycle nature of seismic action leads to the necessity of developing hysteresis models, which would reflect the specific behaviour of the structure not only during loading but also during unloading and subsequent application of force in the opposite direction. …”
Get full text

Low levels of Plasmodium falciparum parasitaemia among patients receiving antiretroviral therapy at the treatment centre of the Regional Hospital Bamenda, Northwest Cameroon. by Calvin Bisong Ebai, Cedric Yamssi, Flore Nguemaïm Ngoufo, Nicaise Ngouemeta Tchoffo, Omarine Nfor Nlinwe, Helen Kuokuo Kimbi

“…<h4>Background</h4>Malaria and HIV are leading causes of death in Africa, including Cameroon. …”
Get full text

PHENETIC ANALYSIS OF POPULUS NIGRA, P. LAURIFOLIA AND P. × JRTYSCHENSIS IN NATURAL HYBRIDIZATION ZONE by A. V. Klimov, B. V. Proshkin

“…Natural selection is most likely the factor governing the inter-population differentiation in P. × jrtyschensis, leading to the predominance of F1 hybrids in populations and hence to a sharp decrease in inter-population variability.…”
Get full text

Designing a competency model for the succession of nursing managers, using the Fuzzy Inference System by Marzieh Khorasani-Gerdehkouhi, Seyed Mahmoud Taheri, Mohammad Ali Cheraghi

“…Results: The results showed that managerial experience, equipment management, emotional intelligence, influence and impact on others, self-confidence, and strategic thinking in the first Fuzzy Inference System level, as well as management abilities, influencing skills, and leading management development in the second level, were more influential. …”
Get full text

Study on Mechanism of Influence of Mining Speed on Roof Movement Based on Microseismic Monitoring by Ke Ma, Su-jian Wang, Fu-zhen Yuan, Yi-lin Peng, Shi-min Jia

“…The increase of large moment magnitude event frequency leads to the decrease of b value. The risk of roof instability and strata behavior increases.…”
Get full text

Application of character based DNA barcode: a novel approach towards identification of fruit fly (Diptera: Tephritidae) species from cucurbit crops by Ankush Mitra, Pubali Mitra, Pradosh Mahadani, Subrata Trivedi, Dhriti Banerjee, Madhusudan Das

“…Numerous species within this family are major agricultural pests, with a tendency to infest a wide array of fruits and vegetables in tropical and sub- tropical regions, leading to considerable damage and consequent reductions in the market value of the crops. …”
Get full text

Axial spondyloarthritis in India: determining the delay in diagnosis, impact on work productivity, and attitude of patients toward treatment by Kamini Narendra Reddy, Asawari Raut, Pravin Patil

“…AxSpA not only reduces work productivity but also leads to work disability. There is a need to address the patient's concerns regarding modern medicine so that their health-seeking behavior is improved.…”
Get full text

Pulmonary cavernous hemangioma: a case report by Wei Li, Xingxing Zheng, Hongzhe Tian, Yu Xi, Yuhao Liu

“…Post-operative histological examination showed that the lesion consisted of dilated nodular hyperplasia rich in red blood cells, leading to a diagnosis of PCH. No recurrence has been observed since postoperative follow-up. …”
Get full text

Construction Payment Automation Through Scan-to-BIM and Blockchain-Enabled Smart Contract by Hamdy Elsharkawi, Emad Elbeltagi, Mohamed S. Eid, Wael Alattyih, Hossam Wefki

“…This study leveraged accurate, real-time building progress data to automate payments using blockchain-enabled smart contracts upon work completion, thus reducing payment disputes by tying payments to verifiable construction progress, leading to faster release of payments. The findings show that this approach provides a transparent basis for payment, enhancing trust and allowing precise project progress tracking.…”
Get full text

Peptic ulcer: does it changed identity? by Ye. A. Pyatenko, A. A. Sheptulin

“…Epigastric pain that develop in fasting state or after food intake remains to be the leading symptom of PU relapse and is observed at 87.5% of male and 95.7% of female patients. …”
Get full text

AIM2 Mediates Inflammation-Associated Renal Damage in Hepatitis B Virus-Associated Glomerulonephritis by Regulating Caspase-1, IL-1β, and IL-18 by Junhui Zhen, Le Zhang, Jiachao Pan, Shumin Ma, Xiaojian Yu, Xiaobo Li, Shijun Chen, Wenjun Du

“…We hypothesized that AIM2 expression is positively correlated with HBV-mediated inflammation in patients with HBV-associated glomerulonephritis (HBV-GN), potentiating inflammation and leading to renal damage. We therefore analyzed the expression of AIM2 and inflammatory factors in HBV-GN tissues and cell lines relative to the inflammatory response to HBV infection and HBV status. …”
Get full text

miR-197 Participates in Lipopolysaccharide-Induced Cardiomyocyte Injury by Modulating SIRT1 by Miaomiao Liu, Ying Zhang, Xiantong Cao, Tao Shi, Yang Yan

“…Sepsis is a systemic inflammation and is capable of inducing myocarditis, which is a major leading cause of death in patients. Studies have found that miR-197 is correlated with the prognosis of patients with inflammatory heart disease, but its effect on sepsis-induced cardiomyocyte injury remains unclear. …”
Get full text

State Power Legitimacy Crisis in the Era of Globalization by I. I. Osvetimskaya

“…The shaking of habitual traditions and norms of behavior leads to the imposed rules rejection and disruption of the consensus-communicative public discourse mechanisms functioning. …”
Get full text