Does forest loss and fragmentation reduce woodpecker-associated ecosystem functions? by Kazuma Yasuda, Daiki Kato, Shoji Naoe, Tatsuya Amano, Tetsuro Yoshikawa, Kahoko Tochigi, Shinsuke Koike

“…In addition, forest loss, not forest fragmentation, was related to decrease in woodpecker abundance, leading to negative cascading effects on the number of tree cavities and fallen trees. …”
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Hippocampal CA1 Pyramidal Neurons of Mecp2 Mutant Mice Show a Dendritic Spine Phenotype Only in the Presymptomatic Stage by Christopher A. Chapleau, Elena Maria Boggio, Gaston Calfa, Alan K. Percy, Maurizio Giustetto, Lucas Pozzo-Miller

“…RTT, an X chromosome-linked disorder associated with mutations in MECP2, is the leading cause of intellectual disabilities in women. …”
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Dynamic response of aerodynamic flutter of blooie line during gas drilling in mountain areas by Dianchen Liu, Peng Yang, Ke Deng, Shijie Tian, Hai Yan, Hongtao Li

“…The results suggest that a large quantity of rock cuttings and rock fragments, suddenly ejected when a high-production reservoir was unexpectedly encountered during drilling, tends to accumulate at the bends, leading to blockages and a reduction in the circulation area. …”
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Discovery of a non‐nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect by Xiyuan Wang, Zhengsheng Zhan, Zhen Wang, Yan Zhang, Kaiyan Zhao, Han Li, Xiaoqian Zhou, Yuting Guo, Fengying Fan, Jian Ding, Meiyu Geng, Xuekui Yu, Wenhu Duan, Zuoquan Xie

“…DW18343 triggered downstream p‐TBK1/p‐IRF3 signaling, leading to the production of multiple cytokines. Additionally, DW18343 displayed broad and long‐lasting antitumor effects in various syngeneic mouse tumor models, whether administered locally or systemically. …”
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Enrichment Mechanism of the Upper Carboniferous-Lower Permian Transitional Shale in the East Margin of the Ordos Basin, China: Evidence from Geochemical Proxies by Zhifu Wei, Yongli Wang, Gen Wang, Ting Zhang, Wei He, Xueyun Ma, Xiaoli Yu

“…The sedimentary environment of marine-continental transitional shale is obviously different from that of marine shale, which leads to different enrichment characteristics of organic matter. …”
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Evaluating Cholinergic Receptor Expression in Guinea Pig Primary Auditory and Rostral Belt Cortices After Noise Damage Using [H]Scopolamine and [F]Flubatine Autoradiography by Taylor J. Forrest MS, Timothy J. Desmond MS, Mohamad Issa MD, Peter J. H. Scott PhD, Gregory J. Basura MD, PhD

“…Noise-induced hearing loss leads to anatomic and physiologic changes in primary auditory cortex (A1) and the adjacent dorsal rostral belt (RB). …”
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MAPK4 inhibits the early aberrant activation of B cells in rheumatoid arthritis by promoting the IRF4-SHIP1 signaling pathway by Pei Huang, Guangli Yang, Pingping Zhang, Yin Zhu, Yaning Guan, Jian Sun, Qian Li, Yang An, Xiaoqi Shi, Juanjuan Zhao, Chaohong Liu, Zhixu He, Yan Chen, Zuochen Du

“…Loss of MAPK4 in KO mice enhances proximal BCR signaling and activates the PI3K-AKT-mTOR pathway, leading to heightened B cell proliferation. Notably, B cells from MAPK4 KO mice produce significantly higher levels of IL-6, a key pro-inflammatory cytokine in RA. …”
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Pharmacological enhancement of slow-wave activity at an early disease stage improves cognition and reduces amyloid pathology in a mouse model of Alzheimer’s disease by Sedef Kollarik, Sedef Kollarik, Sedef Kollarik, Dorita Bimbiryte, Aakriti Sethi, Inês Dias, Inês Dias, Inês Dias, Carlos G. Moreira, Daniela Noain, Daniela Noain, Daniela Noain, Daniela Noain

“…Histochemical assessment of amyloid plaques demonstrated that SO-treated 11-month-old Tg2576 mice had significantly less plaque burden than placebo-treated ones, whereas ELISA of insoluble protein fractions from brains of 6-month-old Tg2576 mice indicated lower Aβ-42/Aβ-40 ratio in SO-treated group vs. placebo-treated controls.DiscussionAltogether, our results suggest that SWA-dependent reduction in brain amyloidosis leads to alleviated behavioral impairment in Tg2576 mice only if administered early in the disease course, potentially highlighting the key importance of early sleep-based interventions in clinical cohorts.…”
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Hypocalcaemic cardiomyopathy: a description of two cases and a literature review by Martin Válek, Lenka Roblová, Ivan Raška Jr., Dita Schaffelhoferová, Tomáš Paleček

“…Hypocalcaemic cardiomyopathy leads to heart failure with reduced ejection fraction in 87% of patients. …”
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Uptake kinetics and distribution of flupyrimin by rice (Oryza sativa L.): Effects of subcellular fractionation and soil factors by Xugen Shi, Min Wang, Zhenyu Jiang, Ruqiang Cui, Baotong Li, Xianpeng Zhang, Lianhu Zhang, Duantao Cao

“…In rice-soil systems, the accumulation of flupyrimin by rice plants is influenced primarily by the soil organic matter content, which leads to increased adsorption of flupyrimin onto soils (R2 > 0.897, P < 0.014). …”
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Household farms facing barriers in indigenous knowledge-based adaptation to extreme climatic events — Evidence from the Huangshui Basin by Hailin Zhang, Jinyan Zhan, Zheng Yang, Huihui Wang, Naikang Xu, Chunyue Bai, Yufei He, Yuhan Cao

“…The increase of the barriers leads to an increase and then a decrease in the possibility of adaptive behavior. (3) Addressing technical barriers is key to rapidly increasing household adaptive behavior in response to ECEs. …”
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The influence of land surface temperature on Ghana’s climate variability and implications for sustainable development by Collins Oduro, Kenny Thiam Choy Lim Kam Sian, Daniel Fiifi Tawia Hagan, Hassen Babaousmail, Brian Odhiambo Ayugi, Yanjuan Wu, Tatenda Dalu, Naicheng Wu

“…Specifically, higher LST leads to decreased precipitation and increased NST, contributing to the increasing trend of NST over the last two decades. …”
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TEAD1‐Mediated Trans‐Differentiation of Vascular Smooth Muscle Cells into Fibroblast‐Like Cells Contributes to the Stabilization and Repair of Disrupted Atherosclerotic Plaques... by Ming Zhai, Zhijun Lei, Yefei Shi, Jiayun Shi, Yanxi Zeng, Shiyu Gong, Weixia Jian, Jianhui Zhuang, Qing Yu, Mark W. Feinberg, Wenhui Peng

“…Insufficient repair of these plaques leads to thrombosis and subsequent ACS. Central to this process is the modulation of vascular smooth muscle cells (VSMCs) phenotypes, emphasizing their pivotal role in atherosclerotic plaque stability and healing post‐disruption. …”
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Adapting to evolving MRI data: A transfer learning approach for Alzheimer’s disease prediction by Rosanna Turrisi, Sarthak Pati, Giovanni Pioggia, Gennaro Tartarisco

“…However, changes in MRI technologies and acquisition protocols often yield limited data, leading to potential overfitting. This study explores Transfer Learning (TL) approaches to enhance AD diagnosis using a Baseline model consisting of a 3D-Convolutional Neural Network trained on 80 3T MRI scans.Two scenarios are explored: (A) utilizing historical data to address changes in MRI acquisitions (from 1.5T to 3T MRI), and (B) adapting 2D models pre-trained on ImageNet (ResNet18, ResNet50, ResNet101) for 3D image processing when historical data is unavailable. …”
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Deep learning technology: enabling safe communication via the internet of things by Ramiz Salama, Hitesh Mohapatra, Tuğşad Tülbentçi, Fadi Al-Turjman

“…Despite offering many advantages, the diversified architecture and wide connectivity of IoT make it vulnerable to various cyberattacks, potentially leading to data breaches and financial loss. Preventing such attacks on the IoT ecosystem is essential to ensuring its security.MethodsThis paper introduces a software-defined network (SDN)-enabled solution for vulnerability discovery in IoT systems, leveraging deep learning. …”
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Using monitoring and simulation to analyze the failure characteristics of multizone landslides controlled by faults: a case study by Jinduo Li, Tianhong Yang, Wenxue Deng, Shigui Du, Penghai Zhang, Jia Wang, Dongdong Sun, Yuan Gao

“…The first failure occurred in a critical area, creating space for further sliding in other regions and reducing lateral constraints in neighboring areas, eventually leading to significant deformations. Therefore, by using this method to identify potential critical areas before landslides occur, targeted mitigation measures can be implemented to reduce the risk of such events.…”
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Targeting tRNA‐Derived Non‐Coding RNA Alleviates Diabetes‐Induced Visual Impairment through Protecting Retinal Neurovascular Unit by Jin Yao, Wen Yao, Jun‐Ya Zhu, Yan Liu, Jin‐Hong Liu, Yu‐Ke Ji, Xi‐Shen Ni, Wan Mu, Biao Yan

“…Abstract Diabetes is a major risk factor for compromised visual health, leading to retinal vasculopathy and neuropathy, both of which are hallmarks of neurovascular unit dysfunction. …”
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The trend of suicide and self-harm in the Chinese population from 2018 to 2022 based on ambulance medical emergency cases: a retrospective study by Ruizhe Yang, Jinsu Zhou, Francis Manyori Bigambo, Wu Yan, Xu Wang, Haibo Yang

“…Descriptive statistics and content analysis were conducted to identify characteristics and themes related to these events, with age groups defined according to American Medical Association standards.ResultsThe study highlights drug poisoning as the leading method, accounting for 63.56% of the 4,103 suicide events. …”
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Is acupuncture effective for knee osteoarthritis? A protocol for a systematic review and meta-analysis by Jing-Wen Yang, Jian-Feng Tu, Myeong Soo Lee, Chuan-Yang Liu, Ling-Yu Qi, Fang-Ting Yu, Shi-Yan Yan, Jin-Ling Li, Lu-Lu Lin, Xiao-Wan Hao, Xin-Tong Su, Li-Qiong Wang

“…Introduction Knee osteoarthritis (KOA) is one of the leading causes of disability. The effectiveness of acupuncture for treating KOA remains controversial. …”
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Sociodemografic and Clinical Characteristics of Suicidal Cases who Attempted to Emergency Services in Ankara by Selma ERCAN, Mustafa AKSOY, Abdussamed YALCIN, A. Cigdem SIMSEK, S. Rahmi ACAR, Tulay ERCIN SAHIN

“…Family (16.0%) and psychiatric disorder (15.2%) are mainly stressors leading to suicide attempted. Discussion: All attempted suicide patients who applied to Emergency Department should be directed to Crisis Intervention Unit immediately and following-up the cases with psychiatric consultation must become obligatory as well as medical treatments. …”
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