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22801
Research hotspots and frontiers of endoplasmic reticulum in glomerular podocytes: a bibliometric and visual analysis from 2005 to 2023
Published 2025-01-01“…Cybulsky, Andrey V, and Papillon, Joan emerge as the most prolific authors, and the Journal of the American Society of Nephrology is the leading journal in this field. China is the top contributor in terms of publications, with McGill University being the most productive institution. …”
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22802
Unveiling urban biodiversity: An interdisciplinary hands-on project that catalyzes awareness
Published 2025-02-01“…Urbanization, a global phenomenon, has significantly transformed ecosystems, often leading to the loss of biodiversity. Despite these challenges, urban green spaces (UGS) continue to serve as essential refuges for diverse flora and fauna within cities. …”
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22803
Rare Occasions: Tidal Disruption Events Rarely Power the AGNs Observed in Dwarf Galaxies
Published 2025-01-01“…We focus on X-ray sources with full-band detections, leading to a sample of 78 AGNs (0.122 ≤ z ≤ 3.515). …”
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22804
Novel inhibitors of the (VIBVN) NAT protein identified through pharmacophore modeling
Published 2025-01-01“…NAT in marine V. vulnificus plays a role in the metabolism of drugs, leading to the development of drug resistance in marine V. vulnificus. …”
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22805
Disaster Control of Roof Falling in Deep Coal Mine Roadway Subjected to High Abutment Pressure
Published 2021-01-01“…In regard to the 5306 coalface in the Tangkou coal mine, Shandong, China, the depth of coal seam is 992.8 m and the stress concentration coefficient of the roadway surrounding rock is 3.33. This leads to a serious deformation of the roadway roof, thereby producing a high risk of the roof falling disaster. …”
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22806
Association between five novel anthropometric indices and erectile dysfunction in US adults from NHANES database
Published 2025-01-01“…Abstract Erectile Dysfunction (ED) is the leading cause of sexual dysfunction affecting hundreds of millions of men worldwide, and has been described as an important public health problem. …”
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22807
Comparison of Resampling Methods and Radiomic Machine Learning Classifiers for Predicting Bone Quality Using Dual-Energy X-Ray Absorptiometry
Published 2025-01-01“…<b>Conclusions</b>: This research demonstrates the potential of radiomic texture features, resampling techniques, and machine learning methods for classifying DXA images into healthy or degraded bone structures, which potentially leads to improved clinical diagnosis and treatment.…”
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22808
Experimental study on the influencing factors of permeability of sand media
Published 2024-11-01“…However, factors such as particle size and compaction of the sand medium, differences between the total dissolved solids (TDS) and the head of the water, and the test temperature, leading to great differences in the results of the Darcy test, cause great uncertainty to the practical application. …”
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22809
FOXC1-mediated serine metabolism reprogramming enhances colorectal cancer growth and 5-FU resistance under serine restriction
Published 2025-01-01“…Serine deprivation activate the ERK1/2-p-ELK1 signaling axis, leading to upregulated FOXC1 expression in CRC cells. …”
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22810
Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome.
Published 2021-12-01“…Here, we generated RTS patient-derived induced pluripotent stem cells (iPSCs) to dissect the pathological signaling leading to RTS patient-associated osteosarcoma. RTS iPSC-derived osteoblasts showed defective osteogenic differentiation and gain of in vitro tumorigenic ability. …”
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22811
Differential Effects of Chronic Pulsatile versus Chronic Constant Maternal Hyperglycemia on Fetal Pancreatic β-Cells
Published 2012-01-01“…These results indicate that late gestation constant maternal hyperglycemia leads to significant β-cell toxicity (increased apoptosis and decreased GSIS). …”
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22812
Modeling dynamic changes in type 1 diabetes progression:Quantifying $\beta$-cell variation after the appearance ofislet-specific autoimmune responses
Published 2009-08-01“…Because of the limited access to pancreatic tissue and pancreatic lymph nodes during the normoglycemic phase of the disease, little is known about the dynamics involved in the chain of events leading to the clinical onset of the disease in humans. …”
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22813
The SGLT-2 Inhibitors and their Role in the Treatment of Heart Failure - A Review of Literature
Published 2025-02-01“…Despite advancements in treatment, HF remains the leading cause of hospitalization among the elderly. …”
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22814
The interplay between persistent pathogen infections with tumor microenvironment and immunotherapy in cancer
Published 2024-09-01“…Unraveling the underlying mechanisms can unveil potential targets for immunotherapy, improving our comprehension of the immune response to cancer and potentially leading to more effective cancer treatments in the future.…”
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22815
DEPEND study protocol: early detection of patients with pancreatic cancer – a pilot study to evaluate the utility of faecal elastase-1 and 13C-mixed triglyceride breath test as scr...
Published 2022-02-01“…Introduction Pancreatic cancer (PC) is the fifth leading cause of cancer-related death in the UK. The incidence of PC is increasing, with little or no improvement in overall survival and the best chance for long-term survival in patients with PC relies on early detection and surgical resection. …”
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22816
Melatonin Rescued Reactive Oxygen Species-Impaired Osteogenesis of Human Bone Marrow Mesenchymal Stem Cells in the Presence of Tumor Necrosis Factor-Alpha
Published 2019-01-01“…This process can contribute to the imbalance of bone remodeling, which ultimately leads to osteoporosis. Therefore, reducing the ROS generation during osteogenesis of BMSCs may be an effective way to reverse the impairment of osteogenesis. …”
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22817
Enhancement of Single‐Molecule Magnet Properties by Manipulating Intramolecular Dipolar Interactions
Published 2025-01-01“…The two COT‐Er units in the newly formed complex are triply bridged by µ‐Cl ligands, leading to the “head‐to‐tail” alignment of the magnetic easy axes distinctly different from the “staggered” arrangement in the precursor complex. …”
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22818
The Efficient Integration of Dust and Numerical Weather Prediction for Renewable Energy Applications
Published 2025-01-01“…Abstract The growing demand for renewable energy underscores the importance of accurate dust forecasting in regions with abundant wind and solar resources. However, leading real‐time global numerical weather prediction (NWP) models often lack dust modules due to computational constraints. …”
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22819
The Relationship between Climbing Ability and Physiological Responses to Rock Climbing
Published 2014-01-01“…However, the increased technical ability and fitness of higher level climbers appears to an extent to offset the increased demand through improved exercise economy which in turn leads to an increased time to exhaustion and an improvement in performance.…”
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22820
Spleno-Mesenteric Venous Blood Flow Dynamics in Adult Patients with Chronic Portal Vein Thrombosis Analyzed by Sequential CT-Spleno- and Mesenterico-Portography
Published 2025-01-01“…Background: Portal vein thrombosis (PVT) leads to portal hypertension (PH) with its sequelae. …”
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