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22781
Treatment of Radiation Bone Injury with Transplanted hUCB-MSCs via Wnt/β-Catenin
Published 2021-01-01“…We found that radiation can damage the DNA of osteoblasts; induce apoptosis; reduce the differentiation, migration, and adhesion of osteoblasts, leading to lipogenesis of bone marrow mesenchymal stem cells (BMSCs) and reducing the source of osteoblasts; and increase the number of osteoclasts in bone tissue, while MSC treatment prevents these changes. …”
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22782
EfficientNet-B0 outperforms other CNNs in image-based five-class embryo grading: a comparative analysis
Published 2024-12-01“…Traditional methods, such as the Gardner grading system, rely on subjective human assessment of morphological features, leading to potential inconsistencies and errors. Artificial intelligence-powered grading systems offer a more objective and consistent approach by reducing human biases and enhancing accuracy and reliability. …”
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22783
Inhibition of Extracellular Calcium Influx Results in Enhanced IL-12 Production in LPS-Treated Murine Macrophages by Downregulation of the CaMKKβ-AMPK-SIRT1 Signaling Pathway
Published 2016-01-01“…Overall, our study demonstrates a new role of transmembrane calcium mobilization in immunity modulation such that inhibition of calcium influx leads to impaired activation of CaMKKβ-AMPK-SIRT1 signaling pathway which lifts restriction on NF-κB activation and results in enhanced IL-12 production.…”
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22784
The Effect of Physical Activity on Alzheimer’s Disease - Systematic Review
Published 2025-01-01“…Physical inactivity is one of the leading modifiable risk factors, contributing to approximately 40% of dementia cases. …”
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22785
Influence of Vibration Isolator Failure on Vehicle Operation Performance and Floating Slab Track Structure Vibration Reduction Effectiveness
Published 2019-01-01“…The different numbers of steel-spring failures will change the natural modal frequency of floating slab to varying degrees, which may cause the resonance of a certain frequency of the vehicle-track coupling system, leading to other track structure diseases.…”
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22786
Zakat-based urban farming: A tool for poverty alleviation, community empowerment, financial inclusion, and food security
Published 2024-03-01“…In collaboration with a leading Islamic bank in Malaysia, the model was pilot tested across selected residential communities in Malaysia. …”
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22787
Lysosome and Cytoskeleton Pathways Are Robustly Enriched in the Blood of Septic Patients: A Meta-Analysis of Transcriptomic Data
Published 2015-01-01“…Background. Sepsis is a leading cause of mortality in intensive care units worldwide. …”
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22788
Impact of Wall Material Composition (Maltodextrin vs. Inulin vs. Nutriose) and Emulsion Preparation System (Nano- vs. Microemulsion) on Properties of Spray-Dried Linseed Oil
Published 2025-01-01“…The addition of nutriose induced the most significant variation in this parameter, with nanoemulsification leading to a 1.6-fold increase in viscosity compared to microemulsification. …”
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22789
Metabolomics insights into doxorubicin and 5-fluorouracil combination therapy in triple-negative breast cancer: a xenograft mouse model study
Published 2025-01-01“…BackgroundBreast cancer is one of the most prevalent malignancies and a leading cause of death among women worldwide. Among its subtypes, triple-negative breast cancer (TNBC) poses significant clinical challenges due to its aggressive behavior and limited treatment options. …”
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22790
The Gut Microbiota in Women Suffering from Gestational Diabetes Mellitus with the Failure of Glycemic Control by Lifestyle Modification
Published 2019-01-01“…Gestational diabetes mellitus (GDM) is prevalent worldwide, leading to a high risk of significant morbidity for both the mother and offspring with complications. …”
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22791
Expression of VEGF-A, Otx Homeobox and p53 Family Genes in Proliferative Vitreoretinopathy
Published 2013-01-01“…Pathological epiretinal membranes grow on the retina surface leading to contraction, and surgery fails in 5% to 10% of the cases. …”
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22792
Achieving high strength, plasticity and conductivity in Cu/Cu-graphene oxide laminated composites with extremely low content of graphene oxide
Published 2025-02-01“…In addition, a nacre-like structure with the oriented arrangement of GO is obtained in Cu-0.3GO layers, which is conductive to carrier transport and leads to a high conductivity of 98.49 %IACS for laminated composites. …”
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22793
Image segmentation and CNN-based deep learning architectures for the modelling on particulate matter formation during solid fuels combustion
Published 2025-03-01“…SiAl readily forms ‘angular’ PM10–200, whereas collisions with fine particles in the gas phase leads to the formation of agglomerated particles of Na/K-Al-Si. …”
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22794
Harnessing Non-Antibiotic Strategies to Counter Multidrug-Resistant Clinical Pathogens with Special Reference to Antimicrobial Peptides and Their Coatings
Published 2025-01-01“…Antimicrobial resistance is a critical global challenge in the 21st century, validating Sir Alexander Fleming’s warning about the misuse of antibiotics leading to resistant microbes. With a dwindling arsenal of effective antibiotics, it is imperative to concentrate on alternative antimicrobial strategies. …”
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22795
The Effect of Contaminants and Temperatures of a High-Palm-Oil Biodiesel Blend on the Lifetime of a Diesel Fuel Filter
Published 2025-01-01“…However, a high concentration of biodiesel, specifically a blending volume of 30% (B30), leads to a shorter fuel filter lifetime compared with pure diesel fuel (B0), due to the precipitation of impurities from biodiesel and the presence of contaminants from the environment. …”
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22796
The mediating effect of self-efficacy and physical activity with the moderating effect of social support on the relationship between negative body image and depression among Chines...
Published 2025-01-01“…Abstract Background Fitness to maintain an ideal body shape is becoming increasingly popular among college students. However, it also leads to many mental health issues. This study explores the pathways through which negative body image affects depression in college students. …”
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22797
Progression of Luminal Breast Tumors Is Promoted by Ménage à Trois between the Inflammatory Cytokine TNFα and the Hormonal and Growth-Supporting Arms of the Tumor Microenvironment...
Published 2013-01-01“…Jointly, TNFα + Estrogen + EGF had a stronger effect on breast cancer cells than each element alone, leading to the following: (1) extensive cell spreading and formation of FAK/paxillin-enriched cellular protrusions; (2) elevated proportion of tumor cells coexpressing high levels of CD44 and β1 and VLA6; (3) EMT and cell migration; (4) resistance to chemotherapy; (5) release of protumoral factors (CXCL8, CCL2, MMPs). …”
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22798
Phenomenological understanding of the contribution of bulk and grain boundary precipitates on strengthening in prolonged-aged Al-Zn-Mg-Cu aluminium alloys
Published 2025-03-01“…Intriguingly, as ageing progressed, significant partitioning of solute-Cu along the interfaces initiated a stacking transition in η-phase from hexagonal C14 to cubic C15 via di-hexagonal C36 Laves phase structures, leading to a reduction in lattice misfit strengthening. …”
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22799
Simulation Analysis of Gas Bubble Formation and Escape in Non-Newtonian Drilling Fluids
Published 2021-01-01“…The shear thinning decreases, and the resistance to the bubble increases as the flow behavior index approaches 1, leading to larger bubble formation times and separation volumes. …”
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22800
Effects of Novaluron Exposure on the Oviposition and Expression of Ovarian Development Related Genes in Silkworm, <i>Bombyx mori</i> (Lepidoptera: Bombycidae)
Published 2024-12-01“…Therefore, we speculated that novaluron can affect the energy metabolism, ovary development, and egg formation of silkworms, thus leading to reproductive disorders of silkworms after novaluron exposure.…”
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