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22561
Influences of Different Factors and Sensitivity Analysis of Permeability of Gassy Coal
Published 2025-01-01“…When the gas pressure is lower than the critical value, the slippage effect plays the leading role in the variation of permeability of the coal; on the contrary, effective stress plays the dominant role. …”
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22562
Fetal and neonatal cardiac tumor diagnosed as Tuberous Sclerosis associated rhabdomyomas resulting from novel pathogenic missense variant detected in TSC2 gene: A case report
Published 2025-03-01“…This pathogenic variant is located on exon 10 of the TSC2 gene, which encodes the hamartin binding domain, leading to impair inhibitory function of the hamartin-tuberin complex, which activates mammalian target of rapamycin(mTOR) activity. …”
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22563
What impact has the NIHR Academic Clinical Fellowship (ACF) scheme had on clinical academic careers in England over the last 10 years? A retrospective study
Published 2017-06-01“…This was performed using mixed methods including routine data collections of career destination, analysis of application rates to doctoral level fellowships and supplemented by survey information that captured the perceived benefits and challenges from previous ACFs and their current career activities.Participants 1239 NIHR ACFs who completed or left their posts between 2006 and March 2015.Results ACFs are perceived by the candidate population as attractive posts, with high numbers of applications leading to high fill rates. Balancing clinical and academic commitments is one of the reported challenges when completing an ACF. …”
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22564
Characterization of acute respiratory infections behavior. Cienfuegos Province. First quarter 2020
Published 2020-10-01“…<br /><strong>Results:</strong> the characterizing essentialities were: its highest incidence in children under five years of age and adults 60 years and over; the leading cause of death was from community-acquired pneumonia; the identified circulating viruses were respiratory syncytial, parainfluenza, unsubtyped influenza A, and coronavirus. …”
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22565
Preparation and application evaluation of monoclonal antibodies against Monkeypox virus A29 protein
Published 2025-01-01“…Then, the mAb-25 was used as a coating antibody to pair with other monoclonal antibodies, leading to the identification of a well-matched antibody pair. …”
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22566
Experimental evidence of flexural phonons in low-temperature heat capacity of carbon nanotubes
Published 2025-04-01“…The grinding effect, associated with the reduction of the size of MWCNTs agglomerates, leads to an increased heat capacity. It was demonstrated that the lowest-temperature heat capacity consists of two main contributions: the Debye (C3T3) and the dispersive (C5T5) one. …”
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22567
A Novel Bimodal Imaging Agent Targeting HER2 Molecule of Breast Cancer
Published 2018-01-01“…The encapsulation efficiency (EE) of IR-783 was 15.09% in the conjugates leading to a successful NIR fluorescence and ultrasound enhancement imaging ex vivo. …”
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22568
The Role of Nature Reserves in Ecosystem Services and Urban Ecological Sustainable Development
Published 2025-01-01“…The results indicate that from 1990 to 2010, the built-up area of Panjin increased by approximately 159%, leading to a reduction in carbon storage, soil retention, and habitat quality by 20%, 4%, and 14%, respectively. …”
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22569
Major Causes of Preventable Death in Trauma Patients
Published 2021-12-01“…Of these, definitely preventable deaths comprised 0.5% and potentially preventable deaths 7.5%. The leading cause of death in trauma patients was traumatic brain injury. …”
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22570
Thermally tunable add-drop filter based on valley photonic crystals for optical communications
Published 2024-10-01“…A diamond-shaped microloop resonator is designed to confine the light and enhance its interaction with the thermal field generated by the microheater, leading to a relatively low power of 23.97 mW needed for switching the output signal from one port to the other. …”
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22571
What about the donor site morbidity – how invasive is the free latissimus dorsi flap?
Published 2024-12-01“…Conclusion: LDM flap surgery leads to a significant impairment of the strength and ROM in the shoulder joint. …”
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22572
An injectable, expandable polyacrylamide cryogel decreases blood loss and improves survival in a porcine model of junctional hemorrhage
Published 2025-02-01“…Abstract Uncontrolled hemorrhage, including junctional hemorrhage, is a leading cause of preventable death in military trauma. …”
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22573
Case report: Illustrating associated malignancies in Paget’s disease using contrast-enhanced mammography
Published 2025-01-01“…CEM findings influenced surgical decisions, leading to total mastectomies with reconstruction instead of conservative approaches. …”
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22574
Controversial Roles of Regenerating Family Proteins in Tissue Repair and Tumor Development
Published 2024-12-01“…The immunogenicity of Reg proteins could recruit immune cells leading to an anti-tumor effect. Such functional diversity is correlated with their structural characteristics: the N-terminal region contributes to autoantigenicity, while the C-type lectin fragment near the C-terminal determines the trophic action. …”
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22575
Artificial intelligence in precision medicine for lung cancer: A bibliometric analysis
Published 2025-01-01“…These publications were mainly published in the following scientific disciplines, including Radiology Nuclear Medicine, Medical Imaging, Oncology, and Computer Science Notably, Li Weimin and Aerts Hugo J. W. L. stand out as leading authorities in this domain. In the keyword co-occurrence and co-citation cluster analysis of the publication, the knowledge base was divided into four clusters that are more easily understood, including screening, diagnosis, treatment, and prognosis. …”
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22576
Niraparib restricts intraperitoneal metastases of ovarian cancer by eliciting CD36-dependent ferroptosis
Published 2025-03-01“…In the context of abundant fatty acids, niraparib elevated intracellular levels of fatty acids and lipid peroxidation, leading to subsequent tumor cell ferroptosis in a p53 and BRCA-independent manner. …”
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22577
High Energy Density Welding of Ni-Based Superalloys: An Overview
Published 2025-01-01“…Nonetheless, the peculiar crystallographic and chemical complexity of Ni-based superalloys (whether characterized by polycrystalline, directionally solidified, or single-crystal microstructure) leads to high susceptibility to welding processes and, in general, challenging issues related to the microstructural features of the welded joints. …”
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22578
Atrioventricular Conduction Delay in the Second Trimester Measured by Fetal Magnetocardiography
Published 2014-01-01“…Slight antibody effects in pregnancy, leading to PR segment prolongation, can already be seen from 18-week gestation onwards by fMCG. …”
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22579
Characterization of Bozitinib as a potential therapeutic agent for MET-amplified gastric cancer
Published 2025-01-01“…Bozitinib demonstrates a strong effect on MET-amplified gastric cancer cells by blocking the c-Met signaling pathway, leading to the inhibition of cell proliferation and survival, as well as the induction of G0/G1 phase arrest and apoptosis. …”
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22580
Modeling and correction of protein conformational disease in iPSC-derived neurons through personalized base editing
Published 2025-03-01“…Mutations in SERPINI1, the gene encoding neuroserpin, can alter protein conformation resulting in cytotoxic aggregation leading to neuronal death. Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is a rare autosomal dominant progressive myoclonic epilepsy that progresses to dementia and premature death. …”
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