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22541
Understanding retinal tau pathology through functional 2D and 3D iPSC-derived in vitro retinal models
Published 2025-01-01“…Our findings reveal that the MAPT mutation leads to delayed retinal cell differentiation and maturation, with tau-mutant disease models exhibiting sustained higher expression of retinal progenitor cell markers and a reduced presence of post-mitotic neurons. …”
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22542
Study on freeze-thaw resistance and pore structure deterioration of fly ash reactive powder concrete based on low-field NMR relaxation
Published 2025-07-01“…The results demonstrate that an appropriate cement replacement with FA can fill the internal pores of the matrix and fully react with Ca(OH)2 for secondary hydration, significantly reduce the number of harmful pores in RPC and optimize the pore size distribution, thus inhibiting the generation of cracks during the freeze-thaw cycle. This replacement leads to reduced mass loss of RPC during cycles and an increase in RDME. …”
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22543
Enhancing grape juice with Lacticaseibacillus rhamnosus CWKu-12: Assessing probiotic viability, physicochemical changes, sensory characteristics, and quality kinetics throughout st...
Published 2025-06-01“…Fruit juices are popular with people of all ages and are seen as healthy and refreshing, leading to interest in creating probiotic functional beverages from them. …”
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22544
Research on the Impact of Blending Dissociated Methanol Gas on the Performance and Emissions of Marine Medium-Speed Methanol Engines
Published 2024-12-01“…The research findings indicate that, under stoichiometric combustion conditions at both rated and idle speeds, the incorporation of DMG leads to increases in the peak in-cylinder pressure, peak heat release rate, and peak in-cylinder temperature, with these peaks occurring earlier. …”
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22545
RNA-Seq Based Transcriptome Analysis of the Type I Interferon Host Response upon Vaccinia Virus Infection of Mouse Cells
Published 2017-01-01“…Transcriptome profiling of L929 cells after incubation with purified recombinant B18 protein showed that attachment of B18 to the cell surface does not trigger cell signalling leading to transcriptional activation. Consistent with its ability to bind type I IFN, B18 completely inhibited the IFN-mediated modulation of host gene expression. …”
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22546
Blockade of Vascular Endothelial Growth Factor Receptor 1 Prevents Inflammation and Vascular Leakage in Diabetic Retinopathy
Published 2015-01-01“…Diabetic retinopathy (DR) is a leading cause of blindness in working age adults. …”
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22547
Measurement of the temperature-dependent cross-plane thermal conductivity of the Li-ion battery pouch cell
Published 2025-01-01“…Due to the lamella structure of Li-ion batteries, their cross-plane thermal conductivity is substantially lower than the in-plane conductivity. This leads to pronounced anisotropy, which complicates the accurate measurement of thermal conductivity, underscoring the importance of precise temperature monitoring to better understand and manage thermal behavior within the battery. …”
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22548
Identification of Potential Serum Metabolic Biomarkers of Diabetic Kidney Disease: A Widely Targeted Metabolomics Study
Published 2020-01-01“…Diabetic kidney disease is a leading cause of chronic kidney disease and end-stage renal disease across the world. …”
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22549
Effect of structural parameters of active pre-chamber on ammonia/hydrogen premixed combustion process: A numerical investigation
Published 2025-01-01“…Moreover, the utilization of active pre-chamber is able to achieve rapid combustion speed, therefore leading to higher overall thermal efficiency. In order to realize an optimized combustion process, it is essential to investigate effects of the structural parameters of active pre-chamber on combustion process. …”
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22550
Analyzing CLIL Studies in Primary Education: Bibliometric analysis
Published 2025-01-01“…Foremost authors included Madrid D and Martinez Agudo JD, while the 'International Journal of Bilingual Education and Bilingualism' emerged as a leading publication venue. Among contributing institutions, the University of Cordoba and University of Granada featured prominently. …”
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22551
Unveiling the Role of Hahani (Paternal Aunts) in the VaTsonga Culture of South Africa
Published 2024-12-01“…To illuminate this subject matter, the paper focused on discussing who the hahani is, her marital counseling role, conflict resolution and leading indigenous rituals in the family from the lived experiences of the authors. …”
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22552
The Analysis of Spatiotemporal Changes in Vegetation Coverage and Driving Factors in the Historically Affected Manganese Mining Areas of Yongzhou City, Hunan Province
Published 2025-01-01“…Manganese ore, as an important strategic metal resource for the country, was subject to unreasonable mining practices and outdated smelting technologies in early China, leading to severe ecological damage in mining areas. …”
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22553
Numerical assessment of solar panel with utilizing ferrofluid flow within wavy duct equipped with V-shaped fins
Published 2025-02-01“…When the Hartmann number is set to 95, an increase in dust levels leads to a reduction of 25.33 % in ηPV and 9.82 % in ηth. …”
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22554
Diagnostic and Surgical Challenges in Recurrent Dermatofibrosarcoma Protuberans: A Case Report
Published 2025-01-01“…Initially, conservative treatment was attempted, but the condition became symptomatic, leading to excision and a diagnosis of Chronic Granulomatous Changes (CGC) and liquefactive necrosis. …”
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22555
A novel sensitizer reduces EGFR-TKI resistance by regulating the PI3K/Akt/mTOR pathway and autophagy
Published 2025-01-01“…However, EGFR-TKI resistance leads to treatment failure. Yifei-Sanjie pill (YFSJ) is a novel type of Chinese patent medicine for lung cancer. …”
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22556
Operative Versus Nonoperative Management of Pyogenic Flexor Tenosynovitis: An Analysis of the National Readmissions Database
Published 2025-01-01“…Infectious complications from the original diagnosis of PFT were the leading causes of readmission. Variables associated with 90-day readmission were higher Charlson comorbidity index, hypertension, Medicaid insurance, longer initial length of hospital stay, tobacco use, and nonsurgical management. …”
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22557
An Unusual Cause of Cardiac Tamponade during Cardiac Catheterization Study
Published 2014-01-01“…On exploration, it was found that there was continuous bleeding from a lacerated epicardial vessel which contributed to the pericardial collection leading to further tamponade effect. This second iatrogenic injury complicated the management of the first iatrogenic cardiac perforation and, thereby, created a life-threatening situation which needed immediate surgical exploration. …”
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22558
When surgery leaves more than just scars: The curious case of gossypiboma— A case report and literature review
Published 2025-03-01“…Owing to its serious medicolegal implications it remains underreported leading to a blurred clinical spectrum. This fact is also depicted in our case which presents an array of nonspecific symptoms painting a picture of possible malignancy. …”
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22559
Optimizing infrared drying of black soldier fly larvae for sustainable cricket feed production
Published 2025-01-01“…Higher temperatures significantly reduced drying time, with 70 °C leading to the fastest drying in ∼5 h. While air velocity had minimal impact on overall drying time, it influenced drying rates. …”
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22560
Economic Evaluations of Health Service Interventions Targeting Patients with Multimorbidities: A Scoping Literature Review
Published 2025-01-01“…Introduction: Multimorbid patients have been growing, leading to an exponential increase in healthcare costs and patterns of resource utilization. …”
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