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22421
Impacts of grade control structures on riverbed degradation
Published 2025-02-01“…Sediment flux of many rivers has been significantly reduced due to human activities caused by economic development, leading to increasingly severe riverbed degradation. …”
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22422
Classifying Food Items During an Eating Occasion: A Machine Learning Approach with Slope Dynamics for Windowed Kinetic Data
Published 2025-01-01“…Increasing the window size from 1 to 5 s leads to a gain in performance for almost all food items. …”
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22423
Simulation Study on Single-Event Burnout Reliability of 900V 4H-SiC Quasi Vertical Double Diffused MOSFET
Published 2025-01-01“…Simulation results indicate that when heavy-ion with linear energy transfer (LET) of 0.5pC/<inline-formula> <tex-math notation="LaTeX">$\mu $ </tex-math></inline-formula>m strikes the device, the primary cause of SEB in the SiC T-QVDMOSFET is the high transient current density and electric field at the trench gate corner. This phenomenon leads to increased power dissipation, resulting in excessive temperatures that ultimately cause thermal failure. …”
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22424
Lacticaseibacillus rhamnosus Fmb14 ameliorates hyperuricemia-induced hepatocyte pyroptosis via NLRP3 inflammasome cascade inhibition
Published 2024-07-01“…Intriguingly, PDIH pyroptosis stimulates the process of apoptosis, which leads to severe leakage of hepatocytes, and both of pyroptosis and apoptosis were decreased after L. rhamnosus Fmb14 treatment. …”
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22425
Diagnostic and prognostic values of tsRNAs in lung cancer: a meta-analysis
Published 2025-01-01“…Abstract Background Lung cancer (LC) is the leading cause of cancer-related death in humans. tRNA-derived small RNA (tsRNA) is a novel biomarker that plays a crucial role in the genesis and development of LC. …”
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22426
A Model of an Integrated Research and Education Program in Space Weather at a Community College
Published 2020-01-01“…Undergraduate research experiences are one of the leading high‐impact practices (HIPs) to encourage students to pursue STEM majors, graduate degrees, and careers. …”
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22427
Effect of crack template structure morphology on electromagnetic shielding efficiency and visual performance of metal mesh optical window
Published 2025-03-01“…Four different acrylic resin colloids were prepared using water, ethylene glycol, glycerol, and N-methylpyrrolidone (NMP), leading to the creation of four mask templates (DP1–DP4).The morphology and structural characteristics of the templates were analyzed using optical and laser confocal microscopy. …”
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22428
APOBEC3C‐mediated NF‐κB activation enhances clear cell renal cell carcinoma progression
Published 2025-01-01“…Upon A3C depletion, essential subunits of the NF‐κB family are abnormally restrained in the cytoplasm, leading to deregulation of NF‐κB target genes. Our study illuminates the pivotal role of A3C in promoting ccRCC tumor development, positioning it as a prospective target for future therapeutic strategies.…”
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22429
Proteomic profiling identifies upregulation of aurora kinases causing resistance to taxane-type chemotherapy in triple negative breast cancer
Published 2025-01-01“…In the current study, we performed an unbiased Reverse Phase Protein Array (RPPA) on TNBC cells treated with chemotherapy compounds and found a leading significant increase of phosphor-AURKA/B/C, AURKA, AURKB, and PLK1, which fall into the mitotic kinase group. …”
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22430
Evaluation of five questionnaires for obstructive sleep apnea screening in the elderly
Published 2025-01-01“…Abstract Obstructive sleep apnea (OSA) often leads to complications in the elderly. This study compares the usefulness of five screening tools for OSA in elderly patients. …”
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22431
Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief
Published 2024-12-01“…We postulate that ENT1 inhibition may enhance extracellular adenosine levels, potentiating endogenous adenosine action at A1R and leading to analgesic effects. Here, we modify the ENT1 inhibitor dilazep based on its complex X-ray structure and show that this modified inhibitor reduces neuropathic and inflammatory pain in animal models while dilazep does not. …”
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22432
Temperature effects on Xe bubble structure and grain boundary migration in UO2: A molecular dynamics simulation
Published 2025-03-01“…Interestingly, reordering of the disrupted atomic structure occurs in Σ5b STGB, which might alter the shear-coupling factor β value from negative to positive, leading to an opposite migration of GBs at 1200 K or higher. …”
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22433
Prevention and management of degenerative lumbar spine disorders through artificial intelligence-based decision support systems: a systematic review
Published 2025-02-01“…Abstract Background Low back pain is the leading cause of disability worldwide with a significant socioeconomic burden; artificial intelligence (AI) has proved to have a great potential in supporting clinical decisions at each stage of the healthcare process. …”
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22434
Neural Network-Based Parameter Estimation and Compensation Control for Time-Delay Servo System of Aeroengine
Published 2025-01-01“…The repetitive, reciprocating motion of the servo system leads to significant changes in its time delay and gain characteristics, and degradation increases the uncertainty of these changes. …”
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22435
Dynamic Hydrogen Production from Methanol/Water Photo-Splitting Using Core@Shell-Structured CuS@TiO2 Catalyst Wrapped by High Concentrated TiO2 Particles
Published 2013-01-01“…The synthesized core@shell-structured CuS@TiO2 particles absorbed a long wavelength (a short band gap) above 700 nm compared to that pure TiO2, which at approximately 300 nm, leading to easier electronic transitions, even at low energy. …”
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22436
Immunoregulative coating for scarless healing in anterior cruciate ligament reconstruction
Published 2025-03-01“…PET's inert surface, lower bioactivity, and mechanical abrasion trigger an M1 macrophage-mediated inflammatory response, leading to excessive, disorganized scar tissue. This scar tissue creates a space-occupying effect at the interface, obstructing graft-bone integration and contributing to bone tunnel enlargement. …”
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22437
Oral Breathing Effects on Malocclusions and Mandibular Posture: Complex Consequences on Dentofacial Development in Pediatric Orthodontics
Published 2025-01-01“…Dentofacial changes in oral breathers include adenoid facies, convex facial profile, and increased lower facial height. Oral breathing also leads to significant changes in cranial posture, often accompanied by mandibular, lingual, and palatal alterations.…”
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22438
Comparative in Vitro Study on the Antimicrobial Efficacy of Endodontic Sealers Against Common Oral Pathogens
Published 2024-12-01“…<b>Background/Objectives</b>: Microorganisms are the leading cause of infections in the root canal system, contributing to the failure of endodontic treatments. …”
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22439
Mechanistic Insights into the Anticancer Potential of Methoxyflavones Analogs: A Review
Published 2025-01-01“…The methoxy group in naturally occurring flavones promotes cytotoxic activity in various cancer cell lines by targeting protein markers, in facilitating ligand–protein binding mechanisms and activating cascading downstream signaling pathways leading to cell death. However, the lipophilic nature of these analogs is a key concern as it impacts drug membrane transfer. …”
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22440
Genomic landscape of head and neck cancer in Asia: A comprehensive meta-analysis of 1016 samples
Published 2024-09-01“…Additionaly, specific mutations like MET in Singaporean patients can be effectively addressed with drugs like Crizotinib, leading to rapid responses in HNSCC. Smokers exhibited high frequencies of CASP8 and FAT1 mutations. …”
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