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22301
Combined BPA and DIBP Exposure Induced Intestinal Mucosal Barrier Impairment Through the Notch Pathway and Gut Microbiota Dysbiosis in Mice
Published 2025-01-01“…Plasticizers can be released from polymers, migrate into food, and be ingested by humans, leading to various health problems. However, little research has investigated the combined toxicity of BPA and DIBP, particularly their intestinal toxicity. …”
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22302
A Body‐Temperature‐Triggered In Situ Softening Peripheral Nerve Electrode for Chronic Robust Neuromodulation
Published 2025-02-01“…However, these mechanically tissue‐like electrodes suffer from unmanageable operating forces, leading to high risks of nerve injury and fragile electrode‐tissue interfaces. …”
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22303
Two-phase Agrawal hybrid nanofluid flow for thermal and solutal transport fluxes induced by a permeable stretching/shrinking disk
Published 2025-01-01“…Also, enhancing the solid volume fraction of nanoparticles leads to a notable rise in the shear stress and heat transfer for both solution branches, whereas the mass transfer rate experiences a reduction.…”
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22304
The FvABF3-FvALKBH10B-FvSEP3 cascade regulates fruit ripening in strawberry
Published 2024-12-01“…FvALKBH10B is induced by phytohormone abscisic acid (ABA), and ABA-Responsive Element Binding Factor 3 (FvABF3), a master regulator in ABA signaling, is responsible for this activation. FvALKBH10B mutation leads to a delay in fruit ripening and causes global m6A hypermethylation of 1859 genes. …”
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22305
Structural Characteristics Analysis of Overlying Rocks and Prevention Measures with a Long-Wall Face Passing Across Abandoned Roadways: A Case Study
Published 2021-01-01“…The results show that the bearing stress in advanced coal pillar is accumulated larger and larger with the width of advanced coal pillar gradually decreasing, and meanwhile, the key stratum in overlying strata would also be sliding instability under some minimum critical width condition; the sudden failure of advanced coal pillar which leads to a sharp increase of bending moment is the key factor that induces fracture of the main roof in front of long-wall face, and the advanced fracture of the main roof can be prevented by changing the stress state of the advanced coal pillar from a two-dimensional state to a three-dimensional state; the method of backfilling abandoned roadway is used to improve the stability of advanced coal pillar and the corresponding monitoring results verify that this method is effective. …”
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22306
Flavonoids of Rosa rugosa Thunb. inhibit tumor proliferation and metastasis in human hepatocellular carcinoma HepG2 cells
Published 2022-03-01“…The results indicated that rose flavonoids at low concentration (10–40 μg/mL) had a better inhibitory effect on migration and invasion of HepG2 cells in a dose-dependent manner, while rose flavonoids at high concentration (80–160 μg/mL) could induce apoptosis of HepG2 cells by up-regulating the expression of pro-apoptotic proteins p53 and Bax, and down-regulating the expression of anti-apoptotic proteins Bcl-2, leading to the functioning of caspase-3 and caspase-9. …”
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22307
Protein dielectric characterization using a tetra square-shaped DNG metamaterial as a differential microwave sensor
Published 2025-12-01“…The incorporation of MM leads to an enhancement in the electric field concentration within the sensing zone of the differential sensor, hence enabling the simultaneous detection of two protein samples. …”
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22308
Deregulation mechanisms and therapeutic opportunities of p53-responsive microRNAs in diffuse large B-cell lymphoma
Published 2025-01-01“…We analyze various molecular mechanisms leading to this dysregulation, including mutations in the TP53 gene, DNA methylation, changes in host-genes expression or microRNA gene copy number, mutations in microRNA and microRNA biogenesis genes.…”
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22309
Spatially mapping the tumour immune microenvironments of non-small cell lung cancer
Published 2025-02-01“…Abstract Lung cancer is the leading cause of cancer-related deaths. An enhanced understanding of the immune microenvironments within these tumours may foster more precise and efficient treatment, particularly for immune-targeted therapies. …”
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22310
Baryon Pasting the Uchuu Light-cone Simulation
Published 2025-01-01“…Additionally, scatter in the thermal pressure and gas density profiles of halos enhances the X-ray and SZ power spectra, leading to biases in cosmological parameter estimates. …”
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22311
Enhancing the Therapeutic Potential of Peptide Antibiotics Using Bacteriophage Mimicry Strategies
Published 2025-01-01“…However, its cationic nature leads to hemolysis and cytotoxicity, which has limited its clinical application. …”
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22312
Immune-endocrine crossroads: the impact of nuclear receptors in Tuberculosis and Chagas disease
Published 2025-02-01“…Unlike acute inflammation, which helps the host respond to pathogens, chronic inflammation leads to metabolic disorders and a dysregulated neuro-immuno-endocrine response. …”
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22313
Quaternized Molecular Brush‐Grafted Injectable Microgel with Anti‐Inflammatory and Drainage Properties for Efficient Therapy of Anal Fistula
Published 2025-02-01“…Traditional treatments often fail to effectively eliminate inflammation and ensure adequate drainage, leading to prolonged healing time and a high recurrence rate. …”
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22314
Assessing moisture content in XLPE power cables using frequency-dependent tangent delta measurements
Published 2025-01-01“…The reliability of cross-linked polyethylene (XLPE)-insulated power cables, mostly used for electricity distribution and transmission in urban areas, is often compromised due to the lack of effective condition-based monitoring systems. This leads to difficulties in early fault detection and increased risk of unscheduled outages, and failures, particularly in cable end terminations. …”
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22315
Physical activity in patients after bariatric surgery - a literature review
Published 2025-01-01“… Introduction: Obesity is a growing global health concern, leading to severe comorbidities such as cardiovascular disease, diabetes, and depression. …”
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22316
Passive and active suppression of transduced noise in silicon spin qubits
Published 2025-01-01“…Here, we demonstrate both open- and closed-loop suppression techniques for the transduced noise in silicon spin qubits, resulting in a more than two-fold (ten-fold) improvement of the inhomogeneous coherence time (Rabi oscillation quality) that leads to a single-qubit gate fidelity of over 99.6% even in the presence of a strong decoherence field gradient. …”
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22317
Asymptomatic Hyperuricemia and the Kidney: Lessons from the URRAH Study
Published 2025-01-01“…This variability complicates the establishment of universal guidelines for treating asymptomatic HSUA, leading to a lack of specific recommendations in clinical practice. …”
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22318
Mitigating CaCO3 crystal nucleation and growth through continuous ion displacement via alternating electric fields
Published 2025-01-01“…We show that at relatively high AC frequencies, incomplete EDL formation leads to an alternating electric field that propagates far into the bulk solution, inducing rapid ion migration that overwhelms the Brownian motion of ions. …”
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22319
Global scenario of silica-associated diseases: A review on emerging pathophysiology of silicosis and potential therapeutic regimes
Published 2025-06-01“…Moreover, it sheds light on diverse mechanisms of silicosis, outlining molecular events and peculiar alterations in lung parenchyma leading to this occupational lung disease. Evaluation of pathophysiological mechanisms could aid in the identification of novel target molecules and treatments; to date, there is no curative treatment for silicosis. …”
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22320
Risedronate Attenuates Podocyte Injury in Phosphate Transporter-Overexpressing Rats
Published 2019-01-01“…Renal dysfunction causes phosphorus accumulation in the circulating plasma and leads to the development of CKD-mineral bone disorder (MBD). …”
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