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22141
Numerical heat transfer analysis considering thermal contact conductance between rough reciprocating sliding surfaces
Published 2025-01-01“…The frictional heat generated leads to elevated surface temperatures, which markedly influence the reliability and service life of friction pairs. …”
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22142
LncRNA PVT1 links estrogen receptor alpha and the polycomb repressive complex 2 in suppression of pro-apoptotic genes in hormone-responsive breast cancer
Published 2025-02-01“…Native immunoprecipitation of nuclear ERα-interacting RNAs coupled to NGS (RIP-Seq) was performed in MCF-7 cells, leading to the identification of essential lncRNAs interacting with the receptor in multi-molecular regulatory complexes. …”
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22143
Using the appropriate modulus of elasticity of periodontal ligament matters in stress analysis of human first premolar tooth and periodontium structures
Published 2025-01-01“…With the low EPDL value, the stress magnitude was overestimated by 1,195%, potentially leading to erroneous conclusions regarding material failure and tooth movement. …”
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22144
Effects of mti-2 Transgenic Potato Plants on the Aphid Myzus persicae (Sternorrhyncha: Aphididae)
Published 2010-01-01“…DM6 and DM11 lines slightly enhanced M. persicae daily fecundity and intrinsic rate of natural increase, leading to a reduction of the doubling time of the populations by 1 day. …”
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22145
DNA replication stress underpins the vulnerability to oxidative phosphorylation inhibition in colorectal cancer
Published 2025-01-01“…This shortage in aspartate, in turn, caused nucleotide deficiencies, leading to S phase cell cycle arrest, replication fork stalling, and enrichment of the p53 pathway, manifestations of replication stress. …”
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22146
Comparison of Medpor Coated Tear Drainage Tube versus Silicon Tear Drainage Tube in Conjunctivodacryocystorhinostomy: Problems and Solutions
Published 2014-01-01“…In our study, the most significant complication we observed in the use of silicon tear drainage tubes was tube extrusion,whereas the leading complication related to the use of Medpor coated tear drainage tubes was tube obstruction.…”
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22147
Electrochemical Study and Determination of Homovanillic Acid, the Final Metabolite of Dopamine, Using an Unmodified Disposable Electrode
Published 2025-01-01“…The type and the composition of the graphite leads used as PGE, the pH of the supporting electrolyte, as well as the scan rates were optimized by CV. …”
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22148
Effect of Cyclic Expansion-Extrusion Process on Microstructure, Deformation and Dynamic Recrystallization Mechanisms, and Texture Evolution of AZ80 Magnesium Alloy
Published 2019-01-01“…The grain refinement changes the deformation and DRX mechanisms of CEE process, which leads the (0002) basal texture intensity first decrease and then increase suddenly. …”
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22149
Comprehensive analysis of advanced glycation end-products in commonly consumed foods: presenting a database for dietary AGEs and associated exposure assessment
Published 2024-07-01“…Assessment of estimated daily intake implied that the contribution of food groups to daily AGE intake varied a lot under different eating patterns, and selection of high-AGE foods leads to up to a 2.7-fold higher intake of AGEs through daily meals. …”
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22150
Review of osteokines in spinal cord injury: potential biomarkers during rehabilitation
Published 2025-01-01“…Abstract After spinal cord injury (SCI), mechanical unloading, denervation, as well as negative changes in blood supply, inflammation state, and hormone levels produce significant negative effects on bone density, leading to a high prevalence of osteoporosis after SCI. …”
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22151
The Neuro-Inflammatory-Vascular Circuit: Evidence for a Sex-Dependent Interrelation?
Published 2020-12-01“…Cardiovascular disease (CVD) is the leading cause of death worldwide with mortality rates in women currently exceeding those in men. …”
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22152
Evolution of Alzheimer’s Disease Therapeutics: From Conventional Drugs to Medicinal Plants, Immunotherapy, Microbiotherapy and Nanotherapy
Published 2025-01-01“…Alzheimer’s disease (AD) represents an escalating global health crisis, constituting the leading cause of dementia among the elderly and profoundly impairing their quality of life. …”
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22153
A glimpse into the future: Integrating artificial intelligence for precision HER2‐positive breast cancer management
Published 2024-09-01“…The advent of deep learning has propelled the artificial intelligence (AI) revolution, leading to an increased applicability of AI in predictive models. …”
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22154
Ligature technique as a treatment for mucocele in an infant - Case report
Published 2024-07-01“… Mucocele is a common benign pathology of the minor salivary glands, caused by trauma that leads to rupture or obstruction of the glandular ducts. …”
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22155
Experimental Investigation into the Bedding Plane Slip Effect on the Overlying Strata Behavior in Longwall Top Coal Caving of Soft Coal Seam
Published 2019-01-01“…The bedding plane slip becomes steady after gradual increase and leads to the subsidence of the overlying strata in the “three-soft” coal seam. …”
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22156
Intravenous Administration of Adipose-Derived Stem Cell Protein Extracts Improves Neurological Deficits in a Rat Model of Stroke
Published 2017-01-01“…While the injection of ADSC leads to a relatively mild but prolonged therapeutic effect, the administration of ADSC-E results in a fast and pronounced clinical improvement which was associated with a unique change in the molecular signature suggesting that potential mechanisms underlying different therapeutic approach may be different. …”
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22157
N6‐Methyladenosine Regulates Cilia Elongation in Cancer Cells by Modulating HDAC6 Expression
Published 2025-01-01“…Collectively, depletion of METTL3‐mediated m6A modification leads to abnormally elongated cilia via suppressing HDAC6‐dependent deacetylation of axonemal α‐tubulin, ultimately attenuating cell growth and cervical cancer development.…”
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22158
Unveiling the Anti-Angiogenic Potential of Small-Molecule (Kinase) Inhibitors for Application in Rheumatoid Arthritis
Published 2025-01-01“…Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation leading to joint damage and systemic complications. …”
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22159
Risk factors for coronary atherosclerotic heart disease in postmenopausal women: a meta-analysis
Published 2025-01-01“…BackgroundCoronary atherosclerotic heart disease (coronary heart disease; CHD) is the leading cause of death in women worldwide, and the number of patients and deaths is increasing each year. …”
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22160
Polystyrene microplastics disrupt adrenal steroid synthesis in male mice via mitochondrial dysfunction
Published 2025-01-01“…In this study, through both in vivo and in vitro models, we found that polystyrene microplastics (PS-MPs) impaired adrenal steroid synthesis, leading to a reduction in corticosterone levels. In vivo, we further observed that chronic exposure to PS-MPs (0.25, 0.5 and 1 mg/d for 4 weeks) could induce abnormal mitochondrial morphology and functional disruptions of adrenal glands in male mice, along with an imbalance in cellular oxidative stress, manifested as increased level of reactive oxygen species, diminished antioxidant activity (glutathione peroxidase and superoxide dismutase). …”
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