Differential Recruitment of Dendritic Cells Subsets to Lymph Nodes Correlates with a Protective or Permissive T-Cell Response during Leishmania (Viannia) Braziliensis or Leishmania... by A. K. Carvalho, K. Carvalho, L. F. D. Passero, M. G. T. Sousa, V. L. R. da Matta, C. M. C. Gomes, C. E. P. Corbett, G. E. Kallas, F. T. Silveira, M. D. Laurenti

“…(V.) braziliensis (Lb) are responsible for a large clinical and immunopathological spectrum in human disease; while La may be responsible for anergic disease, Lb infection leads to cellular hypersensitivity. To better understand the dichotomy in the immune response caused by these Leishmania species, we evaluated subsets of dendritic cells (DCs) and T lymphocyte in draining lymph nodes during the course of La and Lb infection in BALB/c mice. …”
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Guanidines Conjugated with Cell-Penetrating Peptides: A New Approach for the Development of Antileishmanial Molecules by João Victor Marcelino de Souza, Natalia C. S. Costa, Maria C. O. Arruda Brasil, Luana Ribeiro dos Anjos, Renata Priscila Barros de Menezes, Eduardo Henrique Zampieri, Jhonatan Santos de Lima, Angela Maria Arenas Velasquez, Luciana Scotti, Marcus Tullius Scotti, Marcia A. S. Graminha, Eduardo R. Pérez Gonzalez, Eduardo Maffud Cilli

“…In addition, the current compounds have low selectivity for the pathogen, leading to various side effects, which results in lower adherence to treatment. …”
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Blockchain sharding scheme based on generative AI and DRL: Applied to building internet of things by Jinlong Wang, Yixin Li, Yunting Wu, Wenhu Zheng, Shangzhuo Zhou, Xiaoyun Xiong

“…However, since the historical interaction characteristics do not accurately reflect the interaction details within specific fine-grained time periods, this leads to poor system performance. Additionally, the parameter configuration in blockchain sharding systems is mostly based on arbitrary or default settings, which also results in unstable system performance. …”
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High-resolution analysis of hydraulic response characteristics of silted stormwater pipeline and manholes in urban catchments using GASM-TranGRU and CFD-DEM by Danyang Di, Ruoyi Wang, Hongyuan Fang, Mingsheng Shi, Bin Sun, Niannian Wang, Bin Li

“…The local and global feature search capabilities were enhanced by an embedded self-attention network, which in turn established an intelligent early warning model for manhole water levels in silted pipelines.Results:The results of the test analysis showed that, owing to the blocking effect of siltation, the water level of the manhole at the first end of the silted pipe was high, leading to a decrease in the water level of the manhole at the tail end. …”
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Genetic Polymorphisms of Interleukin-1 Alpha and the Vitamin D Receptor in Mexican Mestizo Patients with Intervertebral Disc Degeneration by Salvador Cervin Serrano, Dalia González Villareal, Maribel Aguilar-Medina, Jose Guillermo Romero-Navarro, Jose Geovanni Romero Quintana, Eliakym Arámbula Meraz, Ignacio Osuna Ramírez, Veronica Picos-Cárdenas, Julio Granados, Iris Estrada-García, Guzman Sánchez-Schmitz, Rosalío Ramos-Payán

“…Intervertebral disc degeneration (IDD) is the most common diagnosis in patients with back pain, a leading cause of musculoskeletal disability worldwide. …”
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Global research trends in necrotizing pancreatitis: a bibliometric analysis from 2013 to 2024 by Gulnur G. Gainollina, Murat K. Jakanov, Bazylbek S. Zhakiev, Uteugaly G. Karsakbayev, Kairat R. Taishibayev, Bulat A. Kurmanbayev, Bulat A. Kurmanbayev

“…BackgroundThis study aims to analyzing scientific publications related to necrotizing pancreatitis and its mortality, identifying key areas and trends, and determining the leading research institutions, authors, countries, and journals actively working in this field.MethodsThe Web of Science and Scopus databases were searched for articles on NP published between January 1, 2013, and April 22, 2024. …”
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Infections Caused by Actinomyces neuii: A Case Series and Review of an Unusual Bacterium by Nathan Zelyas, Susan Gee, Barb Nilsson, Tracy Bennett, Robert Rennie

“…Increased use of MALDI-TOF MS MIS is leading to increased detection; thus, understanding the pathogenicity of this bacterium and its typical susceptibility profile will aid clinical decision-making.…”
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Effect of Omega-3 Fatty Acid on the Fatty Acid Content of the Erythrocyte Membrane and Proteinuria in Patients with Diabetic Nephropathy by Su Mi Lee, Seuk Hee Chung, Yongjin Park, Mi Kyoung Park, Young Ki Son, Seong Eun Kim, Won Suk An

“…Diabetic nephropathy is the leading cause of end-stage renal disease and is associated with an increased risk of cardiovascular events. …”
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The Effect of Race, Sex, and Insurance Status on Time-to-Listing Decisions for Liver Transplantation by Cindy L. Bryce, Chung-Chou Ho Chang, Derek C. Angus, Robert M. Arnold, Maxwell Farrell, Mark S. Roberts

“…Fair allocation of organs to candidates listed for transplantation is fundamental to organ-donation policies. Processes leading to listing decisions are neither regulated nor understood. …”
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Postrema area syndrome in the context of systemic lupus erythematosus: Case report by Jose Ricardo Muñoz-Zúñiga, Andrea del Mar Tamayo-Delgado, Alberto Masaru Shinchi-Tanaka, Juan Camilo Márquez, Alex Echeverri-García, Santiago Lopez Garcia

“…Negative anti-aquaporin 4 antibodies ruled out neuromyelitis optica spectrum disorder (NMOSD), leading to a probable diagnosis of APS associated with SLE. …”
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Acute Mesenteric Ischemia after Cardiac Surgery: An Analysis of 52 Patients by Cuneyt Eris, Senol Yavuz, Serhat Yalcinkaya, Arif Gucu, Faruk Toktas, Gunduz Yumun, Burak Erdolu, Ahmet Ozyazıcıoglu

“…Prompt diagnosis and early treatment should be initiated as early as possible in any patient suspected of AMI, leading to dramatic reduction in the mortality rate.…”
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Prevalence of HIV Drug Resistance Mutations in HIV Type 1 Isolates in Antiretroviral Therapy Naïve Population from Northern India by S. Sinha, H. Ahmad, R. C. Shekhar, N. Kumar, L. Dar, J. C. Samantaray, S. K. Sharma, A. Bhargava, R. M. Pandey, R. L. Mitsuyasu, J. L. Fahey

“…The increased use of antiretroviral therapy (ART) has reduced the morbidity and mortality associated with HIV, adversely leading to the emergence of HIV drug resistance (HIVDR). …”
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Analysis of the changes of volatile flavor compounds in a traditional Chinese shrimp paste during fermentation based on electronic nose, SPME-GC-MS and HS-GC-IMS by Ying Li, Li Yuan, Huijie Liu, Hongying Liu, Yue Zhou, Miaonan Li, Ruichang Gao

“…Traditionally fermented shrimp paste has a long fermentation period and is susceptible of external factors, which leads to unstable quality and limits its development and application. …”
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Introducing youth to clinical research: Development and pilot implementation of a children’s activity book by Renee Cadzow, Andy Strohmeier, Erin Carnes, Teresa Quattrin

“…Conclusions: The book is an important advocacy tool with a long-term aim of increasing children’s knowledge and awareness about clinical research, ultimately leading to enhanced participation in clinical research and trials. …”
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Positron Emission Tomography—Computer Tomography Scan Used as a Monitoring Tool Following Cellular Therapy in Cerebral Palsy and Mental Retardation—A Case Report by Alok Sharma, Hemangi Sane, Amruta Paranjape, Nandini Gokulchandran, Pooja Kulkarni, Anjana Nagrajan, Prerna Badhe

“…Cerebral palsy (CP) is one of the non-progressive neurological diseases caused by damage to the brain tissue at birth, which leads to physical, cognitive and perceptive symptoms. …”
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Graded transcendental functions: an application to four-point amplitudes with one off-shell leg by Thomas Gehrmann, Johannes Henn, Petr Jakubčík, Jungwon Lim, Cesare Carlo Mella, Nikolaos Syrrakos, Lorenzo Tancredi, William J. Torres Bobadilla

“…As a first application, we evaluate all integral topologies relevant to the three-loop Hggg and Hgq q ¯ $$ Hgq\overline{q} $$ amplitudes in the leading-colour approximation and heavy-top limit. …”
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Shivering Management in Spinal Anesthesia: Evaluating the Role of Ketamine: A Narrative Review by Siavash Sangi, Mehrdad Mesbah Kiaei, Shahnam Sedigh Maroufi, Maryam Aligholizadeh, Parisa Moradimajd, Azam Saei

“… Background: Shivering is one of the most prevalent known complications due to dysregulation in the thermoregulatory system following regional anesthesia, with an incidence of 65%, leading to unpleasant outcomes and decreased patient satisfaction. …”
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Achieving enhanced strength-ductility synergy in heterogeneous equiaxed structured Ti-6Al-4V alloy sheets by cryogenic pre-stretching by Lingjian Meng, Zhuoya Zhao, Peng Lin, Zhengyi Jiang, Jingwei Zhao

“…For the heterogeneous equiaxed structure, the grain boundaries between large equiaxed and small fragmented α grains act as barriers for dislocation motion and cause the significant strain gradient and back stress strengthening effect, thus leading to an enhanced strength. On the other hand, the lamellar α fragmentation release the large local stress concentration during cryogenic pre-stretching, which maintains the high work hardening capacity of the alloy. …”
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Reduced aerosols and intensified summertime rainfall in India during the pandemic suggest potentially more amplified precipitation in the future by Fan Wang, Meng Gao

“…Reduced aerosol loading leads to a northward shift of the subtropical westerly jet, which induces a westward movement of the subtropical southern branch trough and negative sea-level pressure anomalies over the eastern Arabian Sea. …”
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Strategies for improving the competitiveness of agricultural products and China's trade policy in the world market by Mahammad Aliyev, Mushfig Guliyev, Ulmas Abdullaev, Lamiya Huseynova, Gulnara Azizova

“…The study empirically assessed the performance of leading agricultural companies such as Joyvio Beidahuang Agricultural Holdings, Zheng Dong, Beijing Capital Agro and Rainbow Agro using statistical data and executive interviews. …”
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