Smad2/3 Upregulates the Expression of Vimentin and Affects Its Distribution in DBP-Exposed Sertoli Cells by Xi Zhang, Xiaogang Wang, Taixiu Liu, Min Mo, Lin Ao, Jinyi Liu, Jia Cao, Zhihong Cui

“…The vimentin cytoskeleton in SCs is disrupted by dibutyl phthalate (DBP), which leads to SCs dysfunction. In a previous study, we found that peroxisome proliferator-activated receptor alpha (PPARα) influenced the distribution of vimentin by affecting its phosphorylation in DBP-exposed SCs. …”
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Vaccination and Infection as Causative Factors in Japanese Patients With Rasmussen Syndrome: Molecular Mimicry and HLA Class I by Yukitoshi Takahashi, Kazumi Matsuda, Yuko Kubota, Jiro Shimomura, Etsuko Yamasaki, Tatsuya Kudo, Katsuyuki Fukushima, Hitoshi Osaka, Noriyuki Akasaka, Atsushi Imamura, Shinji Yamada, Naomi Kondo, Tateki Fujiwara

“…Cross-reactivity of cytotoxic T lymphocytes may contribute to the processes leading from infection to the involvement of CNS.…”
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Rare earth alloying in Cu enhances the C/Cu interfacial wettability for long-lasting copper-based electrical contacts by Bingtian Li, Zhenjie Guan, Yang Li, Ziyao Chen, Weijian Li, Liang Zhen, Wenzhu Shao

“…In this work, we theoretically and experimentally demonstrate that rare earth alloying in Cu matrix enhances the interfacial wettability between C and Cu, leading to the improved electrical contact performance. …”
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Effective Method Using a Stool in Cardiopulmonary Resuscitation (CPR) on Dialysis Chair by Takeshi Ifuku, Takashi Hitosugi, Yoshfumi Kawakubo, Tomoyuki Tanaka, Kazuto Doi, Takeshi Yokoyama

“…Heart failure is the leading cause of death in dialysis patients. Cardiac arrest due to hypotension may also occur during dialysis therapy. …”
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Ultrahigh concentration exfoliation and aqueous dispersion of few-layer graphene by excluded volume effect by Zhiyuan Xiong, Luyan Shen, Jin Long, Xiao Li, Ke Zhou, Gyeong Min Choi, Kangtai Ou, GuiYan Yang, Weichun Ma, Heon Sang Lee, Youyi Sun, Dan Li

“…Structural analysis and theoretical modeling suggested that the 2D morphology of the resultant graphene nanosheets facilitates inter-sheet repulsive excluded volume interactions, leading to a fractal jammed network structure composed of nanosheets and tactoids to prevent their agglomeration. …”
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A Novel FS-GAN-Based Anomaly Detection Approach for Smart Manufacturing by Tae-yong Kim, Jieun Lee, Seokhyun Gong, Jaehoon Lim, Dowan Kim, Jongpil Jeong

“…However, collecting and labeling sufficient data to detect anomalies is time-intensive, and abnormal data are rare, leading to data imbalances. The FS-GAN model leverages few-shot learning to enable accurate predictions with minimal data and uses the generative capabilities of AnoGAN to mitigate the scarcity of abnormal data by generating synthetic normal data. …”
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Immunomodulation effects of collagen hydrogel encapsulating extracellular vesicles derived from calcium silicate stimulated-adipose mesenchymal stem cells for diabetic healing by Yen-Hong Lin, Yeh Chen, En-Wei Liu, Mei-Chih Chen, Min-Hua Yu, Cheng-Yu Chen, Chia-Che Ho, Tai-Yi Hsu-Jiang, Jian-Jr Lee, Der-Yang Cho, Ming-You Shie

“…Abstract Diabetic wounds are characterized by chronic inflammation, reduced angiogenesis, and insufficient collagen deposition, leading to impaired healing. Extracellular vesicles (EVs) derived from adipose-derived mesenchymal stem cells (ADSC) offer a promising cell-free therapeutic strategy, yet their efficacy and immunomodulation can be enhanced through bioactivation. …”
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First-principles investigation of local atomic environment and its impact on properties in non-equiatomic CoCrFeNi high-entropy alloys by Qingxu Tian, Fuhui Chen, Peter K. Liaw, Yang Tong, Shuying Chen, Fanchao Meng

“…The CTE analysis indicates that Ni and Cr tend to gain charge, while Co tends to lose charge, leading to modifications in their atomic radii. The SRO analysis suggests that Cr–Fe, Fe–Co, and Cr–Co atomic pairs are highly likely to form short-range ordering. …”
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Early childhood constraint therapy for sensory/motor impairment in cerebral palsy: a randomised clinical trial protocol by Garey Noritz, Olena Chorna, Jill Heathcock, Alexandra Key, Helen Carey, Ellyn Hamm, Mary Ann Nelin, Micah Murray, Amy Needham, James C Slaughter, Nathalie L Maitre

“…Infants with CP have a fundamental disadvantage in recovering motor function: they do not receive accurate sensory feedback from their movements, leading to developmental disregard. Constraint-induced movement therapy (CIMT) is one of the few effective neurorehabilitative strategies shown to improve upper extremity motor function in adults and older children with CP, potentially overcoming developmental disregard.Methods and analysis This study is a randomised controlled trial of children 12–24 months corrected age studying the effectiveness of CIMT combined with motor and sensory-motor interventions. …”
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AMPK: An energy sensor for non-small cell lung cancer progression and treatment by Zhi-Ting Zhong, Xu-Yan Wang, Ying Pan, Ke Zhou, Jing-Hui Chen, Yu-Qi Gao, Bo Dai, Zhi-Ling Zhou, Rui-Qi Wang

“…Lung cancer (LC) is the leading cause of cancer-related morbidity and mortality in China, with non-small cell lung cancer (NSCLC) accounting for 85 % of the overall lung cancer cases. …”
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Convergence of Blockchain, IoT, and AI for Enhanced Traceability Systems: A Comprehensive Review by Yahaya Saidu, Shuhaida Mohamed Shuhidan, Dahiru Adamu Aliyu, Izzatdin Abdul Aziz, Shamsuddeen Adamu

“…Recent research output has notably increased, focusing on agricultural supply chains and SCM, with India and China leading in publications. The analysis shows a predominance of experimental and hybrid methodologies, using Ethereum and Hyperledger Fabric as key platforms. …”
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Delayed Diagnosis of Pharyngeal Perforation following Exploding Tyre Blast Barotrauma by Samantha M. Field, Joseph G. Manjaly, S. Krishan Ramdoo, Huw A. S. Jones, Taran S. Tatla

“…We present a case in which detection proved difficult leading to delayed diagnosis. Case Report. A 27-year-old mechanic presented with haemoptysis, dysphonia, and odynophagia after a car tyre exploded in his face. …”
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Review of Echocardiographic Findings in Patients with Obstructive Sleep Apnea by Radu Sascău, Ioana Mădălina Zota, Cristian Stătescu, Daniela Boișteanu, Mihai Roca, Alexandra Maștaleru, Maria Magdalena Leon Constantin, Teodor Flaviu Vasilcu, Radu Sebastian Gavril, Florin Mitu

“…Obstructive sleep apnea (OSA) causes recurrent apneas due to upper respiratory tract collapse, leading to sympathetic nervous system hyperactivation and increased cardiovascular risk. …”
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Electrodeposition of 4-Benzenesulfonic Acid onto a Graphite-Epoxy Composite Electrode for the Enhanced Voltammetric Determination of Caffeine in Beverages by Leonardo de A. Furtado, Mariana C. de O. Gonçalves, Carlos V. M. Inocêncio, Edilson M. Pinto, Daniela de L. Martins, Felipe S. Semaan

“…Analytical parameters for validation were suitably determined according to local legislation, leading to a linear behaviour from 5 to 150 µmol·L−1; precision of 4.09% was evaluated based on the RDC 166/17, and accuracy was evaluated in comparison with the reference method, with recovery of 98.37 ± 2.58%.…”
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Intrapericardial injection of hydrogels with ASC and their secretome to treat dilated cardiomyopathies by Tácia Tavares Aquinas Liguori, Gabriel Romero Liguori, Viktor Sinkunas, Cristiano Jesus Correia, Raphael dos Santos Coutinho e Silva, Fernando Luiz Zanoni, Vera Demarchi Aiello, Martin Conrad Harmsen, Luiz Felipe Pinho Moreira

“…Abstract Doxorubicin-induced cardiomyopathy (DOX-IC) is a significant and common complication in patients undergoing chemotherapy, leading to cardiac remodeling and reduced heart function. …”
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Wind and rainfall erosion energy in large sediment generating and coarse sediment class areas of the middle Yellow river by Tao Yang, Jianzhi Niu, Dengxing Fan, Di Wang, Yubo Miao, Miao Wang, Chunguang Zhao, Linus Zhang, Xiongwen Chen, Ronny Berndtsson

“…Joint action by strong winds and high-intensive rainfall leads to serious soil erosion problems in large sediment generating and coarse sediment class areas of the middle Yellow River. …”
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Interpretable machine learning modeling of temperature rise in a medium voltage switchgear using multiphysics CFD analysis by Mahmood Matin, Amir Dehghanian, Amir Hossein Zeinaddini, Hossein Darijani

“…In recent decades, leading companies and research groups have extensively conducted Multiphysics computational fluid dynamics (CFD) analyses to evaluate temperature rise in switchgear systems, aiming to meet type-testing requirements specified in IEC standards. …”
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IL-1RN VNTR Polymorphism in Adult Dermatomyositis and Systemic Lupus Erythematosus by Zornitsa Kamenarska, Gyulnas Dzhebir, Maria Hristova, Alexey Savov, Anton Vinkov, Radka Kaneva, Vanio Mitev, Lyubomir Dourmishev

“…A variable number tandem repeat (VNTR) polymorphism of 86 bp in intron 2 of the interleukin-1 receptor antagonist (IL-1RN) gene leads to the existence of five different alleles which cause differences in the production of both IL-1RA (interleukin-1 receptor antagonist) and IL-1β. …”
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Spatiotemporal evolutionary patterns of the hydrochemistry of Jurassic conglomerate aquifers under the influence of curtain walls by Luwang CHEN, Minghui WU, Xiaowei HOU, Yongsheng HU, Miao ZHANG, Xinyue CAI, Xiaoxi YIN, Xiaoping SHI

“…Furthermore, their dissolution will affect the chemical field of groundwater, leading to variations in its hydrochemical composition. …”
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Yaws in Africa: Past, Present and Future by Ezekiel K. Vicar, Shirley V. Simpson, Gloria I. Mensah, Kennedy K. Addo, Eric S. Donkor

“…In line with the WHO’s effort to improve early detection, diagnosis, and proper management leading to the eventual eradication of yaws, this article reviews the existing literature on yaws in Africa to highlight the epidemiological pattern, genetic variability, diagnosis modalities, treatment, and control strategies, the challenges and prospects for yaws eradication. …”
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