IFN-γ reprograms cardiac microvascular endothelial cells to mediate doxorubicin transport and influences the sensitivity of mice to doxorubicin-induced cardiotoxicity by Haoyu Ji, Wenya Ma, Xu Liu, Hongyang Chen, Yining Liu, Zhongyu Ren, Daohong Yin, Ao Cai, Zizhen Zhang, Xin Wang, Wei Huang, Leping Shi, Yanan Tian, Yang Yu, Xiuxiu Wang, Yang Li, Yu Liu, Benzhi Cai

“…IFN-γ stimulation upregulated P-glycoprotein expression, leading to increased DOX efflux and DIC insensitivity. …”
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Locating Station of One-Way Carsharing Based on Spatial Demand Characteristics by Xiaohong Chen, Jiaqi Cheng, Jianhong Ye, Yong Jin, Xi Li, Fei Zhang

“…The main results of this study are presented as follows: (1) different effects of built environment and transportation factors cause dynamic demand across different time periods; (2) factors with positive and negative effect on carsharing demand are divided clearly for guidance of the carsharing station layout; (3) public parking space leads to more personal vehicle trip compared to a carsharing trip; and (4) as public transportation, the relationship of the metro and carsharing is complementary. …”
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In Situ Surface Polymerization of PANI/SWCNT Bilayer Film: Effective Composite for Improving Seebeck Coefficient and Power Factor by Dezhuang Ji, Baosong Li, Balamurugan Thirumal Raj, Xuan Li, Dawei Zhang, Moh'd Rezeq, Wesley Cantwell, Lianxi Zheng

“…However, the uncontrollable interfaces between the components significantly scatter the transport of electrons leading to a reduced thermoelectric performance. In this research, hydrochloride acid doped polyaniline (PANI) is directly prepared on the surface of a single‐walled carbon nanotube (SWCNT) film to form a bilayer structure in controlling the interfacial filtering effect and preserve the high conductivity. …”
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DiffRSS: A Diffusion-Guided Multi-Scale Features Remote Sensing Image Segmentation Method by Honghao Liu, Ruixia Yang, Yue Xu, Zhengchao Chen, Yuyang Zheng

“…We conceptualize the semantic segmentation of remote sensing images as a conditional generation task and design a Multiscale Cyclic Denoising Module (MSCDM), which effectively leverages multiscale features of remote sensing images, leading to superior segmentation outcomes. Inspired by diffusion models, our denoising structure, MSCDM, can be reused multiple times during inference, enhancing the quality of segmentation masks. …”
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RTEL1 is upregulated in gastric cancer and promotes tumor growth by Chunyu Yang, Suzeng Wang, Ge Gao, Peiwen Xu, Mengyuan Qian, Yuan Yin, Surui Yao, Zhaohui Huang, Zehua Bian

“…It is typically diagnosed at advanced stages, leading to a poor prognosis. GC is a highly heterogeneous disease and its progression is associated with complex interplay between genetic and environmental factors. …”
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Piezo1 promotes vibration-induced vascular smooth muscle injury by regulating the NF-κB/p65 axis by Yingshan Zeng, Zhiquan Wu, Mengtian Xiong, Zhishan Liang, Ziyu Chen, Huimin Huang, Hongyu Yang, Qingsong Chen

“…We demonstrated that vibration exposure leads to Piezo1-mediated upregulation of angiogenic chemokines, including CCL2, CCL5, CXCL1, CXCL2, and CXCL10, through the NF-κB/p65 pathway. …”
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Amino Acid Signatures to Evaluate the Beneficial Effects of Weight Loss by Nina Geidenstam, Martin Magnusson, Anders P. H. Danielsson, Robert E. Gerszten, Thomas J. Wang, Lovisa E. Reinius, Hindrik Mulder, Olle Melander, Martin Ridderstråle

“…Weight loss followed by weight maintenance leads to differential changes in amino acid levels associated with obesity. …”
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Tailoring graphite fiber addition to improve high-temperature wear resistance graphite fiber/ Fe composite by Boer Cao, Qinyuan Huang, Yuhao Wu, Hongli Cao, Shangyang Zou, Quan Shan

“…The addition of Gf facilitated the bonding of carbon atoms with alloying elements like Cr, leading to carbide precipitation and a second-phase strengthening effect. …”
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Exploring the impact of elevated pH and short maceration on the deterioration of red wines: physical and chemical perspectives by Carlos Artur Nascimento Alves, Aline Camarão Telles Camarão Telles Biasoto, Grace da Silva Nunes, Hélio Oliveira do Nascimento, Ronaldo Ferreira do Nascimento, Inglides Gomes Oliveira, Patrícia Coelho de Souza Leão, Lucicléia Barros de Vasconcelos

“…The short maceration period reduced phenolic compound extraction in high-pH musts, leading to decreased antioxidant potential and chemical stability. …”
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Anomaly Usage Behavior Detection Based on Multi-Source Water and Electricity Consumption Information by Wenqing Zhou, Chaoqiang Chen, Qin Yan, Bin Li, Kang Liu, Yingjun Zheng, Hongming Yang, Hui Xiao, Sheng Su

“…Despite these advancements, the challenge of fully analyzing and understanding residents’ energy usage behaviors leads to inefficient energy use and potential economic losses. …”
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Locked-in Syndrome: Insights into Etiology, Diagnosis, Management, and Quality of Life by Urszula Zelik, Wojciech Florczak, Joanna Śnieżna, Jakub Dziewic, Karol Dzwonnik, Wiktoria Domino, Gabriela Trestka, Maria Przygoda, Jagienka Włodyka, Kamila Stępień, Sabina Adamczyk

“… Locked-in Syndrome (LIS) is a rare and severe neurological condition resulting from damage to the ventral pons, leading to complete paralysis of voluntary muscles while preserving consciousness and cognitive function. …”
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Peculiarities of Charge Transfer in SiO2(Ni)/Si Nanosystems by Egor Yu. Kaniukov, Dzmitry V. Yakimchuk, Victoria D. Bundyukova, Alena E. Shumskaya, Abdulkarim A. Amirov, Sergey E. Demyanov

“…In the lower temperatures (~200-100 K) a current flow takes place only through the semiconductor due to an increase of resistivity on energy barriers n-Si/metal, which leads to a practically complete exclusion of a participation of the metal in the charge transport process. …”
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Systemic and immunotoxicity induced by topical application of perfluoroheptane sulfonic acid (PFHpS) or perfluorooctane sulfonic acid (PFOS) in a murine model by Lisa M. Weatherly, Hillary L. Shane, Laurel G. Jackson, Ewa Lukomska, Rachel Baur, Madison P. Cooper, Stacey E. Anderson

“…These findings support PFHpS absorption through the skin leading to liver damage and immune suppression.…”
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Shelf-Life Assessment of Canola Protein Bio-Adhesive by Lawrence Tene Tayo, Aldo Joao Cárdenas-Oscanoa, Lizhen Chen, Darshan Shivappa Nayaka, Markus Euring

“…This indicates that the nitrite-crosslinked variants had a more robust chemical formulation, leading to stronger and more durable bonds.…”
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Structural basis for RNA-guided DNA degradation by Cas5-HNH/Cascade complex by Yanan Liu, Lin Wang, Qian Zhang, Pengyu Fu, Lingling Zhang, Ying Yu, Heng Zhang, Hongtao Zhu

“…Upon DNA binding, the Cas5-HNH/Cascade complex adopts a more compact conformation, with subunits converging toward the center of nuclease, leading to its activation. Notably, we also find that divalent ions such as zinc, cobalt, and nickel down-regulate enzyme activity by destabilizing the Cascade complex. …”
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Near Junction Integration of Vapor Chamber for Transient Thermal Performance Improvements of SiC Power Module by Wei Mu, Laili Wang, Haoyuan Jin, Borong Hu, Binyu Wang, Jinfeng Zhang, Liang Wang, Teng Long

“…Power semiconductor modules are mostly stressed when faced with large junction temperature variations, leading to failures such as bond wire lift-off and solder fatigue. …”
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INFLUENCE OF IONIZING IRRADIATION ON THE PARAMETERS OF ZN NANOTUBES ARRAYS FOR DESIGN OF FLEXIBLE ELECTRONICS ELEMENTS by D. B. Kadyrzhanov, M. V. Zdorovets, A. L. Kozlovskiy, A. V. Petrov, V. D. Bundyukova, A. E. Shumskaya, E. Yu. Kaniukov

“…Using the methods of scanning electron microscopy, X-ray diffraction and energy dispersive analysis, the structure of nanotubes having a polycrystalline structure and completely consisting of zinc was studied and it was demonstrated that irradiation with Ar8+ ions with a dose from 1 × 109 to 5 × 1011 ion/cm2 and energy 1.75 MeV/nucleon has an effect on the crystal structure of nanotubes.At high doses, localized highly defect zones arise, leading to a critical change in the structure and physical properties of the nanotubes, respectively. …”
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Exploring the toxicology, socio-ecological impacts and biodegradation of microplastics in Africa: Potentials for resource conservation by Gloria Ifeoma Ujuagu, Onome Ejeromedoghene, Victor Enwemiwe, Chiamaka Linda Mgbechidinma, Ahmed Olalekan Omoniyi, Abiodun Oladipo, Jintu Gu

“…Considering the improper disposal, limited recycling and upcycling intervention, lack of policy, and strict laws against plastic waste management defaulters, the ecosystems in Africa remain immensely impacted by several socio-ecological factors leading to the loss of aquatic organisms through reducing fertility and increasing stress. …”
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DNMT3a Downregulation Ttriggered Upregulation of GABAA Receptor in the mPFC Promotes Paclitaxel‐Induced Pain and Anxiety in Male Mice by Lixia Tian, Xu‐Hui Li, Yu‐Long Zhao, Hui‐Yuan Yi, Xue‐Ru Liu, Rongrong Yao, Xue‐Mei Hou, Xuan Zhu, Fu‐Quan Huo, Tao Chen, Lingli Liang

“…In this study, systemic administration of PTX leads to a decrease in the expression of the DNA methyltransferase DNMT3a, while concurrently upregulating the expression of Gabrb1 mRNA and its encoded GABAARβ1 protein in the medial PFC (mPFC) of male mice. …”
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Early Healing Events around Titanium Implant Devices with Different Surface Microtopography: A Pilot Study in an In Vivo Rabbit Model by Ester Orsini, Stefano Salgarello, Désirée Martini, Beatrice Bacchelli, Marilisa Quaranta, Luciano Pisoni, Emma Bellei, Monika Joechler, Vittoria Ottani

“…In fact, SLA devices showed a more osteoconductive behavior retaining a less dense blood clot, which might be earlier and more easily replaced, and leading to a surface-conditioning layer which promotes osteogenic cell differentiation and appositional new bone deposition at the titanium surface. …”
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