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21701
E3 Ubiquitin Ligase CHIP Inhibits the Interaction between Hsp90β and MAST1 to Repress Radiation Resistance in Non-Small-Cell Lung Cancer Stem Cells
Published 2022-01-01“…Collectively, CHIP promotes the ubiquitination of MAST1 by blocking the interaction of Hsp90β with MAST1, leading to decreased MAST1 protein stability, which suppressed NSCLC stem cell properties and radiation resistance.…”
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21702
New Paradigm in Cell Therapy Using Sperm Head to Restore Brain Function and Structure in Animal Model of Alzheimer’s Disease: Support for Boosting Constructive Inflammation vs. Ant...
Published 2022-01-01“…Based on reproductive immunology, sperm induces constructive inflammatory response and seminal-vesicle-fluid (SVF) suppresses inflammation leading to uterus remodeling. It prompted us to compare therapeutic efficiency of inflammatory or anti-inflammatory approaches in AD model based on reproductive immunology. …”
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21703
Deep Q-Networks for Minimizing Total Tardiness on a Single Machine
Published 2024-12-01“…This underscores the capacity of advanced machine learning techniques to improve industrial scheduling processes, potentially leading to decent operational efficiency.…”
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21704
A Review of Sulfate Removal from Water Using Polymeric Membranes
Published 2025-01-01“…Sulfated waters represent a major challenge on the Canadian prairies, leading to many cattle deaths. While reverse osmosis (RO) membranes effectively remove sulfates, they are costly due to high-pressure requirements. …”
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21705
Enriched environment prevents hypobaric hypoxia induced memory impairment and neurodegeneration: role of BDNF/PI3K/GSK3β pathway coupled with CREB activation.
Published 2013-01-01“…Adverse environmental conditions such as hypobaric hypoxia (HH) cause memory impairment by affecting cellular machinery leading to neurodegeneration. Providing enriched environment (EE) is found to be beneficial for curing several neurodegenerative disorders. …”
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21706
A Generalized Bridge Regression in Fuzzy Environment and Its Numerical Solution by a Capable Recurrent Neural Network
Published 2020-01-01“…So, we perform the presented optimization problem for the model that leads to a multiobjective program. Also, we try to determine the shrinkage parameter and the tuning parameter from the same optimization problem. …”
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21707
Evolution and Attribution Analysis of Habitat Quality in China’s First Batch of National Parks
Published 2024-12-01“…Results showed that grassland and cultivated land were predominantly converted into forestland, leading to improvements in habitat quality in some parks. …”
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21708
Unveiling Green Supply Chain Practices: A Bibliometric Analysis and Unfolding Emerging Trends
Published 2024-12-01“…China, followed by the United States and the United Kingdom, emerged as leading contributors to research in this area, driven by rapid economic growth, heightened environmental concerns, and well-established academic and industrial infrastructures. …”
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21709
Advances in Ultrasound-Targeted Microbubble Destruction (UTMD) for Breast Cancer Therapy
Published 2025-02-01“…Yunfeng Wu,1 Yuxi Liu,2 Han Wu,1 Mengying Tong,1 Linyao Du,1 Shuangsong Ren,1 Ying Che1 1Department of Ultrasound, The First Affiliated Hospital of Dalian Medical University, Liaoning, Dalian, People’s Republic of China; 2Department of Ultrasound, Shandong Second Medical University Affiliated Hospital, Shan Dong, Weifang, People’s Republic of ChinaCorrespondence: Ying Che, Email yche1964@163.comAbstract: Breast cancer is one of the most common types of cancer in women worldwide and is a leading cause of cancer deaths among women. As a result, various treatments have been developed to combat this disease. …”
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21710
Time variations in the generation time of an infectious disease:Implications for sampling to appropriately quantify transmissionpotential
Published 2010-09-01“…If the serial intervals, which eventually determine the generation times, are sampled during the course of an epidemic, direct application of the sampled generation-time distribution to the Lotka-Euler equation leads to a biased estimate of $R_0$. An appropriate quantification of the transmission potential requires the estimation of the cohort generation time during the initial growth phase of an epidemic or adjustment of the time-effect (e.g., adjustment of the growth rate of the epidemic during the sampling time) on the period generation time. …”
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21711
Procoagulant Phospholipids and Tissue Factor Activity in Cerebrospinal Fluid from Patients with Intracerebral Haemorrhage
Published 2014-01-01“…Neuronal apoptosis after intracerebral haemorrhage (ICH) leads to the shedding of procoagulant phospholipids (PPLs). …”
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21712
Uncertainty Quantification for Machine Learning‐Based Ionosphere and Space Weather Forecasting: Ensemble, Bayesian Neural Network, and Quantile Gradient Boosting
Published 2023-10-01“…Techniques that consider only model parameter uncertainties (a and c) predict narrow CI and over‐optimistic results, whereas accounting for both model parameter and data uncertainties with the BNN + D approach leads to a wider CI and the most realistic uncertainties quantification of VTEC forecast. …”
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21713
Patterning Planar, Flexible Li-S Battery Full Cells on Laser-Induced Graphene Traces
Published 2024-12-01“…We show that sulfur can be deposited by selective nucleation and growth on the LIG cathode fingers in a supersaturated sulfur solution. Melt imbibition then leads to loadings as high as 3.9 mg/cm<sup>2</sup> and 75 wt% sulfur. …”
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21714
The Effect of Recycled Crushed Brick Aggregate on the Physical–Mechanical Properties of Earth Blocks
Published 2025-01-01“…This aggregate replacement leads to a reduction in compressive strength (up to −23%) and flexural strength (up to −17.43%); however, all CCB content levels studied met the requirements of the applied standards. …”
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21715
Behaviour and design of extruded high-strength aluminium alloy SHS beam-columns
Published 2024-12-01“…Findings indicated that both the European and Chinese standards tended to provide relatively conservative predictions for buckling resistances, while the American standard sometimes produced predictions leading to higher risk. Finally, a modification strategy for the design of AA7A04-T6 SHS beam-columns, utilizing modified interaction buckling factors that account for non-dimensional member slenderness and compression resistances, was suggested to enhance the precision and reliability of resistance forecasts.…”
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21716
Study on the stability of excavation process of permafrost subgrade slope in Alpine region
Published 2025-02-01“…Under identical temporal conditions, slopes with gentler gradients exhibit relatively shallower thawing depths and demonstrate enhanced stability.When comparing slopes with equivalent ratios and initial water contents, it was observed that maximum thawing depth in frozen soils decreases over time as construction delays occur; thus, later construction leads to diminished impacts on slope stability alongside accelerated freezing rates. …”
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21717
Scoping review of brucellosis in Cameroon: Where do we stand, and where are we going?
Published 2020-01-01“…Cameroon has an opportunity to build public and animal health infrastructure, leading the way for central Africa in the management and future eradication of brucellosis.…”
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21718
Understanding cervical cancer, human papillomavirus (HPV), and HPV vaccine acceptance in college-going students: Institutional-based cross-sectional study from Bihar State
Published 2025-01-01“…Background: Cervical cancer is the second leading cause of cancer-related deaths in Indian women, constituting a significant public health problem. …”
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21719
Age-Dependent Loss of Mitochondrial Function in Epithelial Tissue Can Be Reversed by Coenzyme Q10
Published 2018-01-01“…The fact that there is a significant effect of administered coenzyme Q10 on the respiratory parameters leads to the assumption that this is mainly caused by an increase in the electron transport chain. …”
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21720
A High-Precision Micro-Roll Forming Facility for Fuel Cell Metal Bipolar Plate Production
Published 2025-01-01“…However, micro-roll forming uses multiple sets of forming roll stands to form the part and this leads to technological challenges related to tool alignment and roll tool precision that must be overcome before widespread application can be achieved. …”
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