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21401
Challenges and Choices Amidst Military Conflict: The Present and Future of Medical Education and Healthcare in Sudan
Published 2025-01-01“…Reasons given for leaving included better personal lifestyle, avoiding conflict, advanced training, and better professional opportunities and salary. Leading motives for staying included the pull of friends and family and a sense of responsibility to the country. …”
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21402
GENDER INFLUENCE AND ACADEMIC PERFORMANCE IN NIGERIAN UNIVERSITIES SYSTEM: A STUDY OF BABCOCK UNIVERSITY AND UNIVERSITY OF LAGOS
Published 2024-12-01“…The study revealed that gender discrimination affects both male and female students, leading to lower self-esteem, uneven performance across disciplines, and influencing study time and career choices. …”
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21403
Inference Attacks on Genomic Data Based on Probabilistic Graphical Models
Published 2020-09-01“…The rapid progress and plummeting costs of human-genome sequencing enable the availability of large amount of personal biomedical information, leading to one of the most important concerns — genomic data privacy. …”
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21404
Central amygdala neuroimmune signaling in alcohol use disorder
Published 2025-03-01“…Chronic alcohol consumption disrupts neuroimmune signaling, leading to altered cytokine expression and activation of glial cells, including astrocytes and microglia. …”
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21405
Spatial Estimation of Trophic State for Reservoir Using Ground Monitoring and Remote Sensing Data
Published 2025-01-01“… Nutrient pollution, also known as eutrophication, is a severe environmental problem that leads to harmful algal blooms in water bodies and affects water supplies for human use. …”
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21406
N-Acetylcysteine in Combination with IGF-1 Enhances Neuroprotection against Proteasome Dysfunction-Induced Neurotoxicity in SH-SY5Y Cells
Published 2016-01-01“…In addition, MG132 treatment leads to endoplasmic reticulum (ER) stress and autophagy-mediated cell death. …”
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21407
12,13-diHOME Promotes Inflammatory Macrophages and Epigenetically Modifies Their Capacity to Respond to Microbes and Allergens
Published 2024-01-01“…We hypothesized that macrophages, which are key to both antimicrobial and antigen responses, are functionally and epigenetically modified by 12,13-diHOME leading to short- and long-term dysfunction with consequences for both antimicrobial and antigenic responses. …”
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21408
Activation of cannabinoid type 2 (CB2) receptors promotes the maintenance of redox homeostasis and protects against oxidative distress in the Neotropical freshwater fish matrinxã B...
Published 2024-11-01“…In conclusion, activation of CB1+CB2 receptors disrupted the redox balance, leading to oxidative distress and damage, whereas activation of CB2 preserved oxidative eustress. …”
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21409
Letalidad hospitalaria por enfermedad cerebrovascular en la provincia de Cienfuegos
Published 2014-12-01“…<strong>Background:</strong> cerebrovascular disease is the second leading cause of death in some countries, causing 10 million annual deaths. …”
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21410
Predictive modeling of cattle calving time emphasizing abnormal and normal cases by using posture analysis
Published 2024-12-01“…Additionally, the system differentiates between normal and abnormal calving patterns by analyzing posture sequences leading up to parturition, focusing on timeframes such as 30 min, 1 h, and 2 h pre-calving. …”
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21411
Mediating role of fatigue driving in the influence of job demand and insecurity on safety incidents among bus drivers
Published 2025-01-01“…These are intensified by demanding job conditions and job insecurity, potentially leading to increased safety incidents linked to driver fatigue. …”
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21412
Design and analysis of intelligent service chain system for network security resource pool
Published 2022-08-01“…The traditional network security architecture ensures network security by directing traffic through hardware based network security function devices.Since the architecture consists of fixed hardware devices, it leads to a single form of network security area deployment and poor scalability.Besides, the architecture cannot be flexibly adjusted when facing network security events, making it difficult to meet the security needs of future networks.The intelligent service chain system for network security resource pool was based on software-defined network and network function virtualization technologies, which can effectively solve the above problems.Network security functions of virtual form were added based on network function virtualization technology, combined with the existing hardware network elements to build a network security resource pool.In addition, the switching equipment connected to the network security elements can be flexibly controlled based on software-defined network technology.Then a dynamically adjustable network security service chain was built.Network security events were detected based on security log detection and a expert library consisting of security rules.This enabled dynamic and intelligent regulation of the service chain by means of centralized control in the face of network security events.The deployment process of the service chain was mathematically modeled and a heuristic algorithm was designed to realize the optimal deployment of the service chain.By building a prototype system and conducting experiments, the results show that the designed system can detect security events in seconds and automatically adjust the security service chain in minutes when facing security events, and the designed heuristic algorithm can reduce the occupation of virtual resources by 65%.The proposed system is expected to be applied to the network security area at the exit of the campus and data center network, simplifying the operation and maintenance of this area and improving the deployment flexibility of this area.…”
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21413
Providing a conceptual model to design the municipal office space with an emphasis on the existential approach base on gegoraphical characteristic (Case study: Shahrekord city)
Published 2025-06-01“…Factors that are not adequately considered in the design of the work environment may hinder the proper execution of administrative tasks, consequently leading to a decline in administrative productivity. …”
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21414
Flavonoids as Strong Inhibitors of MAPK3: A Computational Drug Discovery Approach
Published 2023-01-01“…The present study performed molecular docking and dynamics simulation to identify potential MAPK3 inhibitors from natural flavonoids, possibly leading to drug development in cancer therapy. Methods. …”
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21415
The Regional Subsystem Concept: From Heterogeneity to Pluralism
Published 2020-11-01“…The author identifies the key discussion points, which include primarily the nature of relations between subsystem actors: whether they should necessarily be cooperative or not; if they need formal institutionalization and whether they should be organized hierarchically with a strong leading state. The author concludes that despite the absence of expert consensus on these issues, the studies of regional subsystems have come a long way from extreme heterogeneity, even fragmentation of the very basic theoretical premises, to a much greater terminological consistency but have retained the pluralism of views, opinions and assessments.…”
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21416
Stability Improvement of an Efficient Graphene Nanoribbon Field-Effect Transistor-Based SRAM Design
Published 2020-01-01“…The development of the nanoelectronics semiconductor devices leads to the shrinking of transistors channel into nanometer dimension. …”
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21417
Patient satisfaction toward doctor communication in medical clinics: a study from northern Sri Lanka
Published 2024-04-01“…Inadequate communication is a significant factor in determining patients’ discontentment and frustration, which ultimately leads to poor healthcare quality. This is an outpatient clinic-based cross-sectional study, conducted among medical clinic patients in northern Sri Lanka. …”
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21418
New Insights into the PPARγ Agonists for the Treatment of Diabetic Nephropathy
Published 2014-01-01“…Diabetic nephropathy (DN) is a severe complication of diabetes and serves as the leading cause of chronic renal failure. In the past decades, angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin II receptor blockers (ARBs) based first-line therapy can slow but cannot stop the progression of DN, which urgently requests the innovation of therapeutic strategies. …”
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21419
Association of age at menopause with type 2 diabetes mellitus in postmenopausal women: a systematic review and meta-analysis
Published 2024-12-01“…The onset of menopause usually occurs between the ages of 48 and 52, leading to diverse symptoms in various body systems due to a decrease in estrogen level. …”
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21420
Optimization of Poultry Physiological Condition in the Post-Antibiotic Era through Nutritional Intervention – A Review
Published 2024-10-01“…Nutritional intervention can be used to enhance the equilibrium of the gut microbiota in chickens, leading to good physiological effects. Various nutritional interventions have been implemented, including feed additives, vitamins, and fermented and functional feeds. …”
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