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20421
Applying microbial biostimulants and drought-tolerant genotypes to enhance barley growth and yield under drought stress
Published 2025-01-01“…Barley, a staple crop consumed and cultivated globally, is particularly susceptible to the detrimental effects of drought stress, leading to reduced yield production. Water scarcity adversely affects multiple aspects of barley growth, including seed germination, biomass production, shoot and root characteristics, water and osmotic status, photosynthesis, and induces oxidative stress, resulting in considerable losses in grain yield and its components. …”
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20422
IL-1β-Induced Matrix Metalloprotease-1 Promotes Mesenchymal Stem Cell Migration via PAR1 and G-Protein-Coupled Signaling Pathway
Published 2018-01-01“…MMP-1 siRNA transfected MSCs, and MSC pretreatment with IL-1β inhibitor interleukin-1 receptor antagonist (IL-1RA), MMP tissue inhibitor of metalloproteinase 1 (TIMP1), tissue inhibitor of metalloproteinase 2 (TIMP2), MMP-1 inhibitor GM6001, and protease-activated receptor 1 (PAR1) inhibitor SCH79797 confirms that PAR1 protein signaling pathway leads to IL-1β-induced cell migration. In conclusion, IL-1β promotes the secretion of MMP-1, which then activates the PAR1 and G-protein-coupled signal pathways to promote mesenchymal stem cell migration.…”
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20423
Targeting cryptic allosteric sites of G protein-coupled receptors as a novel strategy for biased drug discovery
Published 2025-02-01“…Targeting more variable allosteric sites, which are spatially different from the highly conserved orthosteric sites, represents a novel approach in biased GPCR drug discovery, leading to innovative strategies for targeting GPCRs. …”
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20424
Comparison of Coupled and Uncoupled Modeling of Floating Wind Farms with Shared Anchors
Published 2025-01-01“…The inclusion of wakes in FAST.Farm also reduces the net load on the shared anchor due to the velocity deficit, leading to larger differences between OpenFAST and FAST.Farm (up to 3% difference in mean loads) for load cases with operational turbines.…”
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20425
Ultrastructure of Placenta of Gravidas with Gestational Diabetes Mellitus
Published 2015-01-01“…Gestational diabetes mellitus (GDM) leads to an abnormal placental environment which may cause some structural alterations of placenta and affect placental development and function. …”
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20426
Bibliometric analysis of trends in dental management of the children with Autism Spectrum Disorder (ASD)
Published 2025-01-01“…This study also revealed that most articles involved multinational collaborations, highlighting the global scope of dental research. The United States leads in terms of research output and citations, followed by India and China. …”
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20427
Study on the effects of fissure geometric characteristics on the mechanical behavior and failure mechanism of granite under uniaxial compression test
Published 2025-02-01“…The crack path and failure mode are significantly affected by the change of fissure angle and spacing, while the increase of fissure length and width leads to more rapid failure and lower peak mechanical response. …”
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20428
Semantic Image Synthesis via Class-Adaptive Cross-Attention
Published 2025-01-01“…Thus, they tend to overlook global image statistics, ultimately leading to unconvincing local style editing and causing global inconsistencies such as color or illumination distribution shifts. …”
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20429
Asynchronous Realization of Algebraic Integer-Based 2D DCT Using Achronix Speedster SPD60 FPGA
Published 2013-01-01“…AI DCT is implemented and tested on asynchronous quasi delay-insensitive logic, using Achronix SPD60 field programmable gate array (FPGA), which leads to lower complexity, higher speed of operation, and insensitivity to process-voltage-temperature variations. …”
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20430
C9ORF72 poly-PR induces TDP-43 nuclear condensation via NEAT1 and is modulated by HSP70 activity
Published 2025-01-01“…Under prolonged poly-PR stress, HSP70 delocalizes from TDP-43 NCs, leading to the oligomerization of TDP-43 within these condensates. …”
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20431
Multiscale Thermal Hydraulic Study under the Inadvertent Safety Injection System Operation Scenario of Typical Pressurized Water Reactor
Published 2017-01-01“…It implies the formation of great temperature gradient on the inlet nozzles and RPV wall, leading to the localized stresses and propagation of possible flaws that appeared in the material. …”
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20432
Multi-feature enhancement based on sparse networks for single-stage 3D object detection
Published 2025-01-01“…Analysis of the results leads to the conclusion that our solutions provide accurate and robust detection results. …”
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20433
Michigan tobacco cessation champions: A rapid qualitative analysis
Published 2025-01-01“…Background: Smoking is the leading cause of preventable death in the United States. …”
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20434
Detecting glacial lake water quality indicators from RGB surveillance images via deep learning
Published 2025-02-01“…Global warming has accelerated glacier retreat, subsequently leading to the formation of glacial lakes in high-altitude mountainous regions. …”
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20435
The IVIG treatment response in autoimmune polyendocrine syndromes type 2 with anti-GAD65 antibody-associated stiff person syndrome: a case report and literature review
Published 2025-01-01“…Most practicing neurologists encounter only one or two cases of APS-2 combined with anti-GAD65 antibody-associated SPS in their careers, resulting in underdiagnosis and undertreatment, leading to severe disability and suffering. This case report describes a young male who initially exhibited hair loss, vitiligo, and previously unreported eosinophilia. …”
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20436
Purine-rich element binding protein alpha: a DNA/RNA binding protein with multiple roles in cancers
Published 2025-01-01“…Therefore, dysregulation of DNA/RNA binding proteins such as purine-rich element binding protein alpha (PURα) disrupts signaling transduction and often leads to human diseases including cancer. PURα was initially recognized as a tumor suppressor in acute myeloid leukemia (AML) and prostate cancer (PC). …”
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20437
Prevalence of Precancerous Conditions and Gastric Cancer Based upon the National Cancer Screening Program in Korea for 7 Years, Single Center Experience
Published 2015-01-01“…Gastric cancer is the second most prevalent cancer and the third leading cause of cancer-related deaths in Korea. The National Cancer Screening Program (NCSP) has implemented esophagogastroduodenoscopy (EGD) biennially for all Koreans starting in their 40s. …”
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20438
Inhibition of high glucose-induced cardiac fibroblast activation: an effective treatment for diabetic cardiomyopathy using Chinese herbal medicine
Published 2025-01-01“…MF, as one of the pathological features of DCM at the end stage, is the key factor of poor prognosis leading to ventricular wall stiffness and heart failure, which affects the clinical process and outcome of patients. …”
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20439
Antibacterial properties of substituted phenethylamine-based β-lactam derivatives in oral infections
Published 2025-01-01“…These bacteria act as opportunistic pathogens, potentially leading to serious diseases. Moreover, antibiotic resistance is developing in these pathogenic bacteria, limiting treatment options. β-lactam antibiotics are particularly important due to their broad spectrum and selective toxicity. …”
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20440
Structural Design and Testing of a Corn Header for Soybean–Corn Intercropping
Published 2025-01-01“…By analyzing the corn stalks and the growth conditions of the corn, efforts were made to reduce the loss rate of kernels during harvesting, leading to a structural design of the header frame tailored for the strip intercropping mode. …”
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