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  1. 9761

    Facilitators and barriers affecting the implementation of e-health for chronic respiratory diseases in remote settings: a qualitative evidence synthesis by Emil Matias Salmi, Francesca Wanda Basile, Faiz Ahmad Khan, Larry Watt, Rinn Song, Else Margreet Bijker

    Published 2025-01-01
    “…Good quality, usability, adaptability and efficacy of e-health interventions were important for implementation to be successful, as were adaptation to the local setting — including culture and language —and involvement of relevant stakeholders throughout the process. …”
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  2. 9762

    Clinically meaningful improvements after gene therapy for aromatic L-amino acid decarboxylase deficiency (AADCd) in the Peabody Developmental Motor Scale, Second Edition (PDMS-2) a... by Wuh-Liang Hwu, Hui-Min Lee, John Devin Peipert, Rongrong Zhang, Christian Werner, J. Rafael Sierra, Thomas O’Connell, Jonathan J. Woolley, Marjorie Crowell, Antonia Wang, Ioannis Tomazos

    Published 2025-02-01
    “…We sought to characterize clinically meaningful change in motor function, as measured by Total Peabody Developmental Motor Scales-Second Edition (PDMS-2) score, and assess correlations with cognition and language domains of the Bayley-III and motor milestone (MM) achievement. …”
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  3. 9763

    Why and how should we simulate platform trials? Learnings from EU-PEARL by Elias Laurin Meyer, Tobias Mielke, Marta Bofill Roig, Michaela Maria Freitag, Peter Jacko, Pavla Krotka, Peter Mesenbrink, Tom Parke, Sonja Zehetmayer, Dario Zocholl, Franz König

    Published 2025-01-01
    “…We addressed the functionality limitations of existing software as well as the unavailability of the coding therein by developing a suite of open-source software to use in simulating platform trials based on the R programming language. To give some examples, the newly developed software supports simulating staggered entry of treatments throughout the trial, choosing different options for control data sharing, specifying different platform stopping rules and platform-level operating characteristics. …”
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  4. 9764

    Psychological interventions for chronic non-specific low back pain: protocol of a systematic review with network meta-analysis by Lingxiao Chen, Jill Hayden, Manuela Ferreira, Emma Ho, Milena Simic, Claire Ashton-James, Josielli Comachio, Paulo Ferreira

    Published 2020-09-01
    “…There will be no restriction on language. The primary outcomes will include physical function and pain intensity, and secondary outcomes will include health-related quality of life, fear avoidance, intervention compliance and safety. …”
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  5. 9765

    PENGEMBANGAN MEDIA PEMBELAJARAN INTERAKTIF DENGAN MENGGUNAKAN ADOBE CAPTIVATE PADA MATERI GERAK HARMONIK SEDERHANA by Ramadhanty Mashama Putri, Eko Risdianto, Nyoman Rohadi

    Published 2019-09-01
    “…The results of this research indicated that interactive learning media using Adobe Captivate in simple harmonic motion which developed was included in the very valid category with a percentage of 81% which have high reliability with a score of 0.86 in the material aspect, 0.41 in the aspect of language and 0, 82 on the media aspect. Based on the results and discussion, an interactive learning media was produced by using Adobe Captivate on simple harmonic motion material that had a positive response by teacher and students with a percentage of 84% and 85% and was feasible to use. …”
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  6. 9766
  7. 9767

    Pharmacological and non-pharmacological interventions in patients undergoing nasal surgeries for prevention of emergence agitation: a systematic review and network meta-analysis by Gustavo R.M. Wegner, Bruno F.M. Wegner, Henrik G. Oliveira, Luis A. Costa, Luigi W. Spagnol, Valentine W. Spagnol, Gilberto T.F. de Oliveira Filho

    Published 2025-01-01
    “…Electronic searches, including PubMed, Scopus, Embase, Cochrane Library, and Web of Science, without language or date restrictions, were conducted. Two independent reviewers selected studies, and data extraction was performed using standardized tables. …”
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  8. 9768

    Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models by Wenhui Li, Xianyue Jiang, Wuke Wang, Liya Hou, Runze Cai, Yongqian Li, Qiuxi Gu, Qinchang Chen, Peixiang Ma, Jin Tang, Menghao Guo, Guohui Chuai, Xingxu Huang, Jun Zhang, Qi Liu

    Published 2024-11-01
    “…However, traditional Cas discovery methods relying on sequence similarity may miss distant homologs and aren’t suitable for functional recognition. With protein large language models (LLMs) evolving, there is potential for Cas system modeling without extensive training data. …”
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    Article
  9. 9769

    Risk prediction models for breast cancer: a systematic review by Jiang Li, He Li, Jie He, Ni Li, Yadi Zheng, Zheng Wu, Maomao Cao

    Published 2022-07-01
    “…Search was limited to English language only.Data extraction and synthesis Two reviewers independently screened, reviewed, extracted and assessed studies with discrepancies resolved through discussion or a third reviewer. …”
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  10. 9770

    Effects of isometric contraction training on hypertensive patients: A Systematic Review by Yuan Hao Dong

    Published 2025-01-01
    “…There are no restrictions on language or publishing timeline. The retrieval strategy uses keywords, medical keywords (MeSH), and Boolean conjunctions, including isometric contract or tension, AND (Contract, Isometric or Contracts, Isometric or Isometric Contracts), and AND (Blood Pressure, High or Blood Pressures, High or High Blood Pressure or High Blood Pressures。 …”
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  11. 9771

    Presencia y severidad de calcio coronario: su relación con la aparición de eventos coronarios agudos by Lázaro E. de la Cruz Avilés, Yanier Coll Muñoz, Félix R. Jorrín Román, Juan J. Navarro López, Dayan García Cuesta, Suleidy Castillo Fernández

    Published 2012-03-01
    “…-- @page { margin: 2cm } P { margin-bottom: 0.21cm } A:link { so-language: zxx } --> <!-- @page { margin: 2cm } P { margin-bottom: 0.21cm } -->…”
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  12. 9772

    Antenatal depression among pregnant women in Ethiopia: An umbrella review. by Mesfin Abebe, Yordanos Sisay Asgedom, Amanuel Yosef Gebrekidan, Tsion Mulat Tebeje

    Published 2025-01-01
    “…The search, conducted from August 5 to 15, 2024, used CoCoPop questions and included only English-language reviews. Study quality was assessed with the AMSTAR tool, and data extraction and analysis were performed using Microsoft Excel 2016 and STATA 14.0. …”
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  13. 9773

    Exome sequencing in Nigerian children with early‐onset epilepsy syndromes by Ibitayo Abigail Ademuwagun, Yagoub Adam, Solomon Oladapo Rotimi, Steffen Syrbe, Maximilian Radtke, Julia Hentschel, Johannes R. Lemke, Ezekiel Adebiyi

    Published 2025-02-01
    “…The integration of genomic medicine into epilepsy management in Nigeria holds promising prospects for improving patient care and reducing mortality rates. Plain Language Summary This study represents the first published exome findings in Nigerian children with early‐onset epilepsy, revealing a genetic diagnosis in 27% of cases. …”
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  14. 9774

    Key Drivers of Consumption, Conceptual, Sensory, and Emotional Profiling of Cheeses Based on Origin and Consumer Familiarity: A Case Study of Local and Imported Cheeses in Greece by Malamatenia Panagiotou, Efstathios Kaloudis, Danai Ioanna Koukoumaki, Vasiliki Bountziouka, Evangelia Giannakou, Margarita Pandi, Konstantinos Gkatzionis

    Published 2024-10-01
    “…Sensory and emotional attributes of local, local PDO, and imported cheeses, as well as drivers associated with consumers’ choice and acceptance above and beyond their sensory attributes, were studied using three methods: (a) flash profile to gain insight into the sensory positioning of products and description of samples; (b) qualitative analysis of focus groups to pinpoint consumer knowledge, preference, and consumption criteria; and (c) a new methodology for natural language processing and sentiment analysis of social media posts to determine consumer conceptualizations. …”
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  15. 9775

    Population Size Estimation of Men Who Have Sex With Men in Low- and Middle-Income Countries: Google Trends Analysis by Carly M Malburg, Steve Gutreuter, Horacio Ruiseñor-Escudero, Abu Abdul-Quader, Wolfgang Hladik

    Published 2025-01-01
    “…We conducted a sensitivity analysis in a subset of countries (n=14) examining the effect of alternative English search terms, different language search terms (Spanish, French, and Swahili), and alternative search years (2019 and 2021). …”
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  16. 9776
  17. 9777
  18. 9778

    Freedom of expression, aspiration and gender: A cultuling in the student demonstration by Siti Nurbayani, Elly Malihah, Millary Agung Widiawaty, Moh. Dede, Bayu Iqbal Anshari, Asep Mahpudz, Erry Sukriah, Sri Wahyuni

    Published 2025-01-01
    “…Men tended to use more direct language, whereas women used examples from their everyday lives. …”
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  19. 9779

    The adaptation process of a safety planning intervention to promote connectedness and reduce distress in Diné adolescents and adults during the COVID-19 pandemic by Joshuaa Dominic Allison-Burbank, Vanessa Begaye, Kyann Dedman-Cisco, Lisa Jim, Shannon Archuleta, Renae Begay, Lacey Howe, Emily E. Haroz

    Published 2025-01-01
    “…The first case of COVID-19, or Dikos Ntsaaígíí-19 in the Diné (Navajo) language, arrived in the Southwest in March 2020. The virus quickly spread amongst Diné communities and contributed to immediate school closures. …”
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  20. 9780

    Systematic literature review on Calcium Pyrophosphate Deposition (CPPD) nomenclature: condition elements and clinical states— A Gout, Hyperuricaemia and Crystal-Associated Disease... by Georgios Filippou, Antonella Adinolfi, Emilio Filippucci, Nicola Dalbeth, Robert Terkeltaub, Tristan Pascart, Edoardo Cipolletta, Silvia Sirotti, Charlotte Jauffret, Sara Tedeschi, Daniele Cirillo, Luca Ingrao, Alessandro Lucia

    Published 2025-01-01
    “…This systematic literature review constituted its first step and aimed to provide a state-of-the-art analysis of the medical literature of the last 20 years.Methods A systematic literature search was undertaken in the PubMed, Cochrane and Embase databases between 2000 and 2022, restricted to studies on humans and in the English language. Eight reviewers independently and manually extracted labels related to CPPD concepts, according to an a priori list generated by the authors: pathogenic conditions and pathogenic crystal labels, elementary imaging condition elements and asymptomatic and symptomatic condition states. …”
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