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3541
Digital transformation and the fluid workforce: skill development and capacity building for railway workers
Published 2025-02-01“…This research provides a novel framework for enhancing worker competencies in the digitally evolving railway construction landscape, integrating SNA with strategic workforce development approaches. …”
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3542
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3543
Differential Intestinal Mucosa Transcriptomic Biomarkers for Crohn’s Disease and Ulcerative Colitis
Published 2018-01-01“…Genetic research has shaped the inflammatory bowel disease (IBD) landscape identifying nearly two hundred risk loci. …”
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3544
Extinction studies in focus: Reflections on photography at a time of ecological decline
Published 2025-01-01“…Through compositional inclusion or exclusion, the photograph can assert and communicate what belongs in a picture, in a landscape, in an ecosystem. It can illuminate what we deem conservation-worthy, or, on a larger scale, which extinctions are attention-worthy. …”
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3545
Spaced Seed Data Structures for De Novo Assembly
Published 2015-01-01“…Here, we revisit the DBG paradigm to adapt it to the changing sequencing technology landscape and introduce three data structure designs for spaced seeds in the form of paired subsequences. …”
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3546
A Particle Swarm Optimization Variant with an Inner Variable Learning Strategy
Published 2014-01-01“…Although Particle Swarm Optimization (PSO) has demonstrated competitive performance in solving global optimization problems, it exhibits some limitations when dealing with optimization problems with high dimensionality and complex landscape. In this paper, we integrate some problem-oriented knowledge into the design of a certain PSO variant. …”
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3547
Oral Squamous Cell Carcinoma: Features and Medico-Legal Implications of Diagnostic Omission
Published 2024-01-01“…This study is aimed at examining in depth, through the presentation of a specific clinical case, the medico-legal aspects inherent to the diagnosis of oral cancer, analyzing the preventive, interceptive, and diagnostic strategies, the legal implications of clinical evaluation errors and diagnostic omission, and the type of medical damage produced and professional liability. The medico-legal landscape surrounding oral squamous cell carcinoma is multifaceted and characterized by diagnostic challenges, treatment complexities, and legal considerations. …”
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3548
Changes in the Microbiome During Chronic Rhinosinusitis
Published 2024-12-01“…The persistence of inverted papillomas warrants investigation into their pathogenesis and how they may contribute to a nasal landscape promoting the chronicity of CRS. Further investigation is needed to uncover the interplay between resident microbiota and viral, fungal, and immunological influence. …”
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3549
Priming of prosopis cineraria (L.) druce and acacia tortilis (forssk) seeds with fulvic acid extracted from compost to improve germination and seedling vigor
Published 2015-07-01“…Composting of waste plant materials and its use in agriculture and landscape sites is an environmental friendly way of reducing waste material and conserving the environment. …”
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3550
Economic consequences of the First World War
Published 2024-01-01“…The hypothesis is that the war's consequences significantly shaped the economic and social landscape of the world throughout the 20th century. …”
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3551
The schematic structure of folk discourses of Toba Caldera Geosites as the collective memory for tourist destinations at lake Toba area
Published 2025-12-01“…To maximize the impact, they should be presented in regional, national, and foreign languages, including Batak script, through both conventional and online platforms, thus enriching the language landscape of the Lake Toba area.…”
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3552
D-2-hydroxyglutarate impairs DNA repair through epigenetic reprogramming
Published 2025-02-01“…Abstract Cancer-associated mutations in IDH are associated with multiple types of human malignancies, which exhibit distinctive metabolic reprogramming, production of oncometabolite D-2-HG, and shifted epigenetic landscape. IDH mutated malignancies are signatured with “BRCAness”, highlighted with the sensitivity to DNA repair inhibitors and genotoxic agents, although the underlying molecular mechanism remains elusive. …”
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3553
INSTINCT: Multi-sample integration of spatial chromatin accessibility sequencing data via stochastic domain translation
Published 2025-02-01“…Integrative analysis of multiple spATAC-seq samples, for which no method has been developed, allows for effective identification and elimination of unwanted non-biological factors within the data, enabling comprehensive exploration of tissue structures and providing a holistic epigenomic landscape, thereby facilitating the discovery of biological implications and the study of regulatory processes. …”
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3554
Global scientific performance and research trends of the interrelation between climate change and economic growth
Published 2025-01-01“…Our research contributes to the existing literature by providing a detailed mapping of the intellectual landscape and suggesting directions for future research to support effective climate policies.…”
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3555
Environmental influence and species occurrence of yellowjacket drones in an invaded area
Published 2025-01-01“…Such behavior is likely driven by a complex combination of individual and species-specific traits, environmental influence, and landscape cues. Our field study aimed to determine factors affecting the occurrence of Vespula spp. drones, focusing on the influence of vegetation traits, atmospheric factors and diel effects, and the species occurrence proportion in an invaded area in Patagonia. …”
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3556
Strategies to Identify Recognition Signals and Targets of SUMOylation
Published 2012-01-01“…Furthermore, an integrative analysis of known and putative SUMO substrates illustrates an updated landscape of several SUMO-regulated events. The strategies and analysis presented here should contribute to the understanding of SUMO-controlled functions and provide rational approach to identify biomarkers or choose possible targets for intervention in processes where SUMOylation plays a critical role.…”
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3557
Effects of a Severe Mountain Pine Beetle Epidemic in Western Alberta, Canada under Two Forest Management Scenarios
Published 2010-01-01“…When the outbreak occurred in each scenario, sufficient pine remained on the landscape for the beetle to cause the timber supply to collapse. …”
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3558
Interference of a phytoconstituent from Nymphaea lotus-derived ligand N-acetyl glucosamine with signaling receptors in diabetes mellitus development: A targeted computational analy...
Published 2025-01-01“…Molecular dynamics simulation, principal component analysis, and free energy landscape analysis showed that the binding affinity of the Nymphaea lotus complex was higher than that of reference ligands. …”
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3559
Evolution of CpG-islands by means of tandem duplications
Published 2017-02-01“…In particular, they: a) initiate transcription as promoters in most (> 50 %) genes of vertebrates, in some cases bi-directional, due to self-complement feature of cg dinucleotides; b) form a global methylation landscape; c) act as a transcription “switch” via methylation. …”
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3560
Responsible Email Marketing in Higher Education
Published 2024-10-01“…This paper explores the nuanced landscape of responsible email marketing within higher education, focusing on balancing effective communication and ethical considerations. …”
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