Reims antique, acquis et perspectives by Magalie Cavé, Philippe Rollet, Régis Bontrond

“…Some portions of large ancient buildings are still visible within the landscape today (the Mars Gate, cryptoporticus, and bathhouses). …”
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L’enterrement d’une triade divine féminine à Lugdunum : étude du dépôt de la place d’Albon à Lyon (Métropole de Lyon) by Lucas Guillaud, Emmanuel Bernot, Aline Colombier-Gougouzian, Amaury Gilles, Nicolas Garnier

“…It was sealed with a large marble slab and marked in the landscape by a tile placed on edge on the wall of the horreum.The collection comprises a large bronze vessel that serves as a container for other objects. …”
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New era towards autonomous additive manufacturing: a review of recent trends and future perspectives by Haolin Fan, Chenshu Liu, Shijie Bian, Changyu Ma, Junlin Huang, Xuan Liu, Marshall Doyle, Thomas Lu, Edward Chow, Lianyi Chen, Jerry Ying Hsi Fuh, Wen Feng Lu, Bingbing Li

“…The additive manufacturing (AM) landscape has significantly transformed in alignment with Industry 4.0 principles, primarily driven by the integration of artificial intelligence (AI) and digital twins (DT). …”
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A comprehensive environmental index for monitoring ecological quality of typical alpine wetlands in Central Asia by Jiudan Zhang, Junli Li, Changming Zhu, Anming Bao, Amaury Frankl, Philippe De Maeyer, Tim Van de Voorde

“…Meanwhile, improvements were also observed in hydrological conditions, vegetation vitality, and aboveground biomass, coupled with a reduction in wetland landscape fragmentation, improving ecological stability. …”
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Hepatocellular carcinoma risk scores for non-viral liver disease: A systematic review and meta-analysis by Laura Burke, Alexander Hinkson, Vincent Haghnejad, Rebecca Jones, Richard Parker, Ian A. Rowe

“…This study addresses the gap in understanding the performance of current HCC risk models in patients with non-viral liver diseases, reflecting the epidemiological landscape of liver disease in Western countries. In our review of these models we identified several key concerns regarding reporting standards and risk of bias and confirmed that patients with alcohol-related liver disease and metabolic dysfunction-associated steatotic liver disease are underrepresented in model development and validation cohorts. …”
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Investigating intra‐tumoural heterogeneity and microenvironment diversity in primary cardiac angiosarcoma through single‐cell RNA sequencing by Jingyuan Huo, Zhen Wang, Wenting Zhao, Miao Chen, Haoyang Li, Fengpu He, Xiao Tian, Yaqi Ma, Firyuza Husanova, Liang Ma, Yiming Ni, Hongda Ding, Weidong Li, Hongfei Xu

“…Conclusion This study elucidates the complex cellular landscape and immune microenvironment of PCAS, highlighting potential molecular targets for the development of novel therapies. …”
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A Case Report and Genetic Characterization of a Massive Acinic Cell Carcinoma of the Parotid with Delayed Distant Metastases by Anthony C. Nichols, Michelle Chan-Seng-Yue, John Yoo, Sumit K. Agrawal, Maud H. W. Starmans, Daryl Waggott, Nicholas J. Harding, Samuel A. Dowthwaite, David A. Palma, Kevin Fung, Bret Wehrli, S. Danielle MacNeil, Philippe Lambin, Eric Winquist, James Koropatnick, Joe S. Mymryk, Paul C. Boutros, John W. Barrett

“…Future large-scale efforts will be necessary to define the mutational landscape of salivary gland malignancies to identify therapeutic targets and biomarkers of treatment failure.…”
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Ferroptosis in kidney disease: a bibliometric analysis from 2012 to 2024 by Yuxin Hu, Yuxin Hu, Yuxin Hu, Jingyi Tang, Jingyi Tang, Jingyi Tang, Hanzhang Hong, Hanzhang Hong, Yexin Chen, Yexin Chen, Beibei Ye, Ziheng Gao, Ziheng Gao, Gegongming Zhu, Lin Wang, Lin Wang, Lin Wang, Weijing Liu, Weijing Liu, Weijing Liu, Yaoxian Wang, Yaoxian Wang, Yaoxian Wang

“…In recent years, however, there has been a shift towards biomarkers, inflammation and necrosis, which indicate current and future research directions in this area.ConclusionThe global landscape of the ferroptosis research in kidney disease from 2012 to 2024 was presented. …”
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Spatio-temporal dynamics of speleothem growth and glaciation in the British Isles by S. Panitz, S. Panitz, M. Rogerson, J. Longman, N. Scroxton, T. J. Lawson, T. C. Atkinson, V. Ersek, J. Baldini, L. Baldini, S. Umbo, M. A. Lone, G. M. Henderson, S. F. M. Breitenbach

“…Further study of leads and lags in speleothem growth compared to surface deposition may provide new insights into landscape-scale dynamics during ice sheet growth and retreat.…”
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Performance of a hybrid capture-based target enrichment next-generation sequencing for the identification of respiratory pathogens and resistance-associated genes in patients with... by Wei-Yu Hsu, Ting-Wei Kao, Hsin-Ching Cho, Sheng-Yuan Ruan, Tai-Fen Lee, Yu-Tsung Huang, Jung-Yien Chien

“…This study aimed to elucidate the efficacy of a hybrid capture-based target enrichment next-generation sequencing technique (Respiratory Pathogen ID/AMR Enrichment Panel, RPIP) as exemplified in a cohort with severe pneumonia. Pathogen landscape in the population was illustrated by these three methodologies. …”
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Uncovering the whole genome silencers of human cells via Ss-STARR-seq by Xiusheng Zhu, Lei Huang, Chao Wang, Guoli Li, Biao Deng, Dashuai Kong, Xiaoxiao Wang, Rongrong Chang, Yi Gu, Qiuhan Wen, Siyuan Kong, Yuwen Liu, Yubo Zhang

“…In summary, this study pioneers the elucidation of the genome-wide silencer landscape in human cells, delineates their global regulatory features, and identifies specific silencers influencing cancer cell proliferation.…”
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Effects of mosquito-proofing storm drains on adult and larvae mosquito abundance: Protocol of the IDAlErt storm drAin randomiSed controlled trial (IDEAS) by Marina Treskova, Tomás Montalvo, Joacim Rocklöv, Charles Hatfield, Frederic Bartumeus, Shouro Dasgupta, João Encarnação, Rachel Lowe, Jan C. Semenza, Pascale Stiles, Jordi Noya, Andrea Valsecchi, Till Bärnighausen, John R.B. Palmer, Aditi Bunker

“…Cities contain numerous landscape and infrastructure elements, such as storm drains, that allow stagnant water build-up facilitating mosquito breeding. …”
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Genealogy of the Arab tribes living in Syria during the Caliphate of Imam Ali (AS)Typology of the Arab Tribes Living in the Levant during the Caliphate of Imam Ali (AS) Typology... by Akram sadat Hoseini, Yahya Mirhoseini

“…These insights can contribute to further research on Muawiya's policies, the Alavi-Umayyad conflict, and the sociopolitical landscape of the Levant. Keywords: Imam Ali (AS), Typology, Levant/Sham Tribes, Qahtanians, Adnanians, Muawiya. …”
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Evaluating the Effectiveness of Cyclin-Dependent Kinase 4/6 Inhibitors in Early- and Very Early-Onset Metastatic Breast Cancer: A Multicenter Study by Akif Doğan, Nurullah İlhan, Goncagül Akdağ, Sedat Yıldırım, Mustafa Seyyar, Zeynep Yüksel Yaşar, Hande Nur Erölmez, Heves Sürmeli, Buğra Öztosun, Özlem Nuray Sever, Hatice Odabaş, Mahmut Emre Yıldırım, Devrim Çabuk, Nedim Turan, Mahmut Gümüş

“…By advancing our understanding of the clinical and molecular landscape of early-onset breast cancer and very early-onset breast cancer, this study lays the groundwork for improving outcomes in these underserved patients through tailored therapeutic approaches.…”
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Impacts of genomic alterations on the efficacy of HER2-targeted antibody–drug conjugates in patients with metastatic breast cancer by Riqing Huang, Anqi Hu, Qixiang Rong, Ditian Shu, Meiting Chen, Wei Yang, Yue Zhang, Qiufan Zheng, Xin An, Cong Xue, Haifeng Li, Yanxia Shi

“…Abstract Background HER2-targeted antibody–drug conjugates (ADCs) have revolutionized the treatment landscape of metastatic breast cancer. However, the efficacy of these therapies may be compromised by genomic alterations. …”
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Changes of Narrative: Osvald Sirén’s Photographic Modeling of Modern Research on Chinese Garden by Jiuwen GU, Yuanfeng SHI, Shan JIA

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Research Progress in and Planning Strategies for Multi-scale Measurement of the Efficiency of Urban Blue-Green Infrastructure in Carbon Sink Enhancement and Emission Reduction by Song LIU, Zhaocheng BAI, Dizi LIU, Peiyu SHEN

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Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease by Zhen Zhu, Guangxin Luan, Song Wu, Yiyi Song, Shuang Shen, Kaiyue Wu, Shengnan Qian, Weiping Jia, Jun Yin, Tao Ren, Jianping Ye, Li Wei

“…Conclusions Our research suggests that scRNA-seq can reflect the multifaceted mitochondrial landscape of DKD renal tubular cells after drug treatment, and these findings may provide new targets for DKD therapy at the organelle level.…”
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Spatiotemporal analysis of Plasmodium falciparum erythrocyte binding antigen-175 gene dimorphism in Ghana by Abraham Y. Kpirikai, Belinda A. Ofosu, Josie N. A. Okai, Victor Kornu, Abdul Rashid Kassim, Esther Donkor, Frederica Malm, Osumanu Ahmed, Mona-Liza E. Sakyi, Samirah Saiid, Albert Yao Kudakpo, Charles Mensah, Francis Dzabeng, Collins Morang’a, Gordon A. Awandare, Yaw Aniweh, Lucas N. Amenga-Etego

“…There is paucity of data on the prevalence of these alleles and their epidemiology in the Ghanaian malaria landscape and hence this study. Methods Parasite gDNA was extracted from archived Dried Blood Spots (DBS) prepared from 700 confirmed malaria-infected individuals and analysed for P. falciparum EBA-175 dimorphism. …”
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Real‐world effectiveness and safety of oral azvudine versus nirmatrelvir‒ritonavir (Paxlovid) in hospitalized patients with COVID-19: a multicenter, retrospective, cohort study by Haiyu Wang, Guangying Cui, Ming Cheng, Tuerganaili Aji, Guotao Li, Xinjun Hu, Guangming Li, Shixi Zhang, Yanyang Zhang, Linqi Diao, Pan Li, Ling Wang, Yiqiang Yuan, Guowu Qian, Ruiqing Zhang, Xiaoli Jin, Juan Wang, Hong Luo, Donghua Zhang, Mingming Wang, Silin Li, Zhan Song, Mengzhao Yang, Guanyue Su, Ranran Sun, Junbiao Chang, Zujiang Yu, Zhigang Ren

“…Single-cell RNA sequencing was performed to elucidate the tumor immune landscape after azvudine treatment. After propensity score matching, 2404 azvudine and 1202 Paxlovid recipients from Henan Province were included. …”
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