Infiltrating T lymphocytes and tumor microenvironment within cholangiocarcinoma: immune heterogeneity, intercellular communication, immune checkpoints by Yunyan Dai, Chenyang Dong, Zhiming Wang, Yunpeng Zhou, Yi Wang, Yi Hao, Pinggui Chen, Chaojie Liang, Chaojie Liang, Gaopeng Li, Gaopeng Li

“…In this review, we describe the heterogeneous immune landscape and intercellular communication in cholangiocarcinoma and summarize the specific distribution of T lymphocytes. …”
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Bibliometric and visual analysis in the field of electroacupuncture’s analgesia and regulation on negative emotion from 2014 to 2024 by Xubo Huang, Jiajie Gao, Yuxin Ding, Jiali Wang, Junfan Fang, Junfan Fang, Jianqiao Fang, Jianqiao Fang, Junying Du, Junying Du

“…IntroductionThis bibliometric study systematically analyzes the research landscape of electroacupuncture (EA), focusing on its applications in pain relief and emotional regulation from 2014 to 2024. …”
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Study on SHP2 Conformational Transition and Structural Characterization of Its High-Potency Allosteric Inhibitors by Molecular Dynamics Simulations Combined with Machine Learning by Baerlike Wujieti, Mingtian Hao, Erxia Liu, Luqi Zhou, Huanchao Wang, Yu Zhang, Wei Cui, Bozhen Chen

“…Meanwhile, we explored the free energy landscape of SHP2 activation using enhanced sampling technique (meta-dynamics simulations), which provides insights into its conformational changes and activation mechanism. …”
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Seeking abortion medications online: experiences from a mystery client study in Colombia by Daniel Arango Arango, Alice F Cartwright, Ava Braccia, Ann Moore, Maria M Vivas

“…Accurate medication abortion information specific to Colombia should be made more accessible so that people can more easily navigate the new care landscape.…”
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STAMBPL1/TRIM21 Balances AXL Stability Impacting Mesenchymal Phenotype and Immune Response in KIRC by Shiyu Huang, Xuke Qin, Shujie Fu, Juncheng Hu, Zhengyu Jiang, Min Hu, Banghua Zhang, Jiachen Liu, Yujie Chen, Minghui Wang, Xiuheng Liu, Zhiyuan Chen, Lei Wang

“…Abstract Kidney renal clear cell carcinoma (KIRC) is recognized as an immunogenic tumor, and immunotherapy is incorporated into its treatment landscape for decades. The acquisition of a tumor mesenchymal phenotype through epithelial‐to‐mesenchymal transition (EMT) is associated with immune evasion and can contribute to immunotherapy resistance. …”
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Mapping integral cell-type-specific interferon-induced gene regulatory networks (GRNs) involved in systemic lupus erythematosus using systems and computational analysis by Blessy Kiruba, Akshayata Naidu, Vino Sundararajan, Sajitha Lulu S

“…Although extensive research has been conducted on SLE pathogenesis, a comprehensive understanding of its molecular landscape in different cell types has not been achieved. …”
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Molecular dependencies and genomic consequences of a global DNA damage tolerance defect by Daniel de Groot, Aldo Spanjaard, Ronak Shah, Maaike Kreft, Ben Morris, Cor Lieftink, Joyce J. I. Catsman, Shirley Ormel, Matilda Ayidah, Bas Pilzecker, Olimpia Alessandra Buoninfante, Paul C. M. van den Berk, Roderick L. Beijersbergen, Heinz Jacobs

“…Type 3 deletions are abundant in human tumors, can dominate the deletion landscape, and are associated with DNA damage response status and treatment modality. …”
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Improved Estimation of Aboveground Biomass in Rubber Plantations Using Deep Learning on UAV Multispectral Imagery by Hongjian Tan, Weili Kou, Weiheng Xu, Leiguang Wang, Huan Wang, Ning Lu

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Bibliometric Analysis and ChatGPT-Assisted Identification of Key Strategies for Improving Primary Maternity Care Based on a Decade of Collective Research by Maulana S, Iqhrammullah M, Pratama R, Tjandra S, Mulya IC, Haroen H

“…A bibliometric analysis was conducted using data from the Scopus database to map the research landscape and identify latent research topics in maternal health care. …”
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Conservation value and ecosystem service provision of Nothofagus antarctica forests based on phenocluster categories by Guillermo J. Martínez Pastur, Julián Rodríguez-Souilla, Yamina M. Rosas, Natalia Politi, Luis Rivera, Eduarda M. O. Silveira, Ashley M. Olah, Anna M. Pidgeon, María V. Lencinas, Pablo L. Peri

“…Conservation value and capacity to supply ES significantly varied among phenocluster categories: (i) cultural, regulating, and provisioning ES and potential biodiversity at landscape level, (ii) soil carbon and nitrogen, (iii) dominant height, crown cover, basal area, total volume, and domestic animal stock, and (iv) understory plant richness and cover at stand level. …”
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Research hotspots and frontiers of endoplasmic reticulum in glomerular podocytes: a bibliometric and visual analysis from 2005 to 2023 by Wang Junli, Hao Zhihong, Wang Lina, Ou Qiaoqun, Qu Jing, Hu Jiaqi, Shengyou Yu, Shengyou Yu, Shengyou Yu

“…BackgroundThe glomerular podocyte endoplasmic reticulum is a critical component in renal function, yet its research landscape is not fully understood. This study aims to map the existing research on podocyte endoplasmic reticulum by analyzing publications in the Web of Science Core Collection (WOSCC) from the past 19 years.MethodsWe conducted a bibliometric analysis using Citespace, VOSviewer, the Metrology Literature Online platform, and the Bibliometrix software package to visualize and interpret the data from WOSCC. …”
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SEGMENTATION OF YOUNG ADULT TOURISTS VISITING CROATIAN CITIES: A HUNGARIAN CASE STUDY by Anetta MÜLLER, Éva Bába BÁCSNÉ, Gábor Gergely RÁTHONYI, Jordán Tütünkov-HRISZTOV, Noémi KULCSÁR, Erzsébet RÁKÓ, Sándor KOVÁCS, Attila LENGYEL

“…Croatia's allure as a cultural, natural, and historical destination in the global tourism landscape has garnered increasing interest from international travelers, including Hungarian tourists. …”
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DCLRE1B as a novel prognostic biomarker associated with immune infiltration: a pancancer analysis by Mi Zou, Zuxi Feng, Kaibo Hu, Yuan Shu, Ting Li, Xiaogang Peng, Leifeng Chen, Leyang Xiao, Shouhua Zhang, Ting Xiong, Xueqiang Deng, Jie Peng, Liang Hao

“…DCLRE1B was also found to be associated with the immune landscape and various immune biomarkers and regulators. …”
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Regional Medical Campuses in Canada by Aaron Johnston, Amanda Bell, Kristy Penner, Trushar Patel, Grace Perez

“… Background: Regional Medical Campuses (RMCs) are an established part of the Distributed Medical Education (DME) landscape in Canada. Combined model RMCs, offering both preclinical and clinical education have shown promising results in producing physicians who work in rural and regional settings and are currently a key avenue of expansion of medical training in Canada. …”
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Empowering Security Operation Center With Artificial Intelligence and Machine Learning—A Systematic Literature Review by Mohamad Khayat, Ezedin Barka, Mohamed Adel Serhani, Farag Sallabi, Khaled Shuaib, Heba M. Khater

“…As a result, SOCs struggle to address the evolving threat landscape due to their reliance on isolation technologies and reactive strategies. …”
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Metaverse Clinic for Pregnant Women With Subclinical Hypothyroidism: Prospective Randomized Study by Yuanyuan Zheng, Yizhen Chen, Yan Chen, Liang Lin, Ting Xue, Chuhui Chen, Junping Wen, Wei Lin, Gang Chen

“… BackgroundHealth care is experiencing new opportunities in the emerging digital landscape. The metaverse, a shared virtual space, integrates technologies such as augmented reality, virtual reality, blockchain, and artificial intelligence. …”
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Awareness and Attitude Toward Artificial Intelligence Among Medical Students and Pathology Trainees: Survey Study by Anwar Rjoop, Mohammad Al-Qudah, Raja Alkhasawneh, Nesreen Bataineh, Maram Abdaljaleel, Moayad A Rjoub, Mustafa Alkhateeb, Mohammad Abdelraheem, Salem Al-Omari, Omar Bani-Mari, Anas Alkabalan, Saoud Altulaih, Iyad Rjoub, Rula Alshimi

“…ObjectiveThis study aims to assess and compare medical AI-related attitudes among medical students in general medicine and in one of the visually oriented fields (pathology), along with illuminating their anticipated role of AI in the rapidly evolving landscape of AI-enhanced health care. MethodsThis was a cross-sectional study that used a web-based survey composed of a closed-ended questionnaire. …”
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University Leadership: Transparency in Communication with External Stakeholders by Nadiia Artyukhova, Olena Churikanova, Kseniia Bliumska-Danko

“…The clustering method provided essential insights into which institutions lead in transparency and where improvements are necessary, reinforcing that transparency is key to ensuring competitiveness within the higher education landscape. This research broadens the understanding of transparency in higher education, offering practical recommendations for universities seeking to enhance their external communication practices. …”
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Genomic characterization and molecular predictive biomarkers for chemotherapy in patients with metastatic triple-negative breast cancer treated in a real-world setting by Erik Olsson, Henrik Lindman, Evangelos Digkas, Viktoria Thurfjell, Haidar Mir Ali, Ute Krüger, Anna-Karin Wennstig, Marie Sundqvist, Antonios Valachis

“…Further research into the genomic landscape of tumors from patients with rapid progression or exceptional response to different treatment strategies can provide insights into mechanisms of resistance and identify predictive biomarkers.…”
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Assessment of historical and future changes in temperature indices for winegrape suitability in Hungarian wine regions (1971–2100) by László Lakatos, Richárd Nagy

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