A suite of wildlife crossing structures facilitates mammal movement across tropical forest fragments in a city by Li Si Tay, Ruisheng Choo, Max D. Y. Khoo, Eunice Kong, Yi Xiang Chan, Wivian H. Y. Neo, Sebastian Ow, Yuet Hsin Toh, Han Ling, Malcolm C. K. Soh, Benjamin P. Y.‐H. Lee, Adrian H. B. Loo, Kenneth B. H. Er

“…Thus, a variety of infrastructure and measures to accommodate the diversity of wildlife moving across forest patches in a fragmented landscape is recommended.…”
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A scoping review on the obstacles faced by beta thalassemia major patients in Pakistan- Matter of policy investment by Ali Hussain Ansari, Saqib Hussain Ansari, Mubarak Jabeen Salman, Muhammad Usman Hussain Ansari, Rawshan Jabeen

“…Additionally, we critically analyzed the current landscape of β-TM in Pakistan. The main challenges in β-TM care in Pakistan are suboptimal transfusion services and a poor complication management. …”
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Preclinical evaluation of avutometinib and defactinib in high‐grade endometrioid endometrial cancer by Tobias Max Philipp Hartwich, Miranda Mansolf, Cem Demirkiran, Michelle Greenman, Stefania Bellone, Blair McNamara, Shuvro P. Nandi, Ludmil B. Alexandrov, Yang Yang‐Hartwich, Silvia Coma, Jonathan Pachter, Alessandro D. Santin

“…Methods Whole‐exome sequencing (WES) was used to evaluate the genetic landscape of five primary EAC cell lines. The in vitro activity of avutometinib and defactinib as single agents and in combination was evaluated using cell viability, cell cycle, and cytotoxicity assays. …”
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Outcomes of oncologic arthroplasty in children and adolescents with malignant limb tumors: a systematic review by Vyacheslav I. Zorin, Sergei V. Vissarionov, Alexandr Y. Makarov, Timofey S. Rybinskikh, Kristina N. Rodionova

“…However, the development and refinement of chemotherapy and radiotherapy protocols, along with advances in surgical techniques and implants, have significantly altered the treatment landscape for these patients. Currently, limb-sparing oncologic arthroplasty is the preferred surgical approach for treating limb sarcomas in children. …”
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Integrated bioinformatics analysis identified cuproptosis-related hub gene Mpeg1 as potential biomarker in spinal cord injury by Dandan Mao, Qi Chen, Shuolan Tong, Zixia Xu, Guofeng Yu, Chuan Chang, Yao Lv

“…Additionally, relying on the immune infiltration landscape associated with cuproptosis, we carried out immune cell correlation analysis on hub genes. …”
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Spatially mapping the tumour immune microenvironments of non-small cell lung cancer by Lysanne Desharnais, Mark Sorin, Morteza Rezanejad, Bridget Liu, Elham Karimi, Aline Atallah, Anikka M. Swaby, Miranda W. Yu, Samuel Doré, Saskia Hartner, Benoit Fiset, Yuhong Wei, Baharak Kadang, Roni Rayes, Philippe Joubert, Sophie Camilleri-Broët, Pierre-Olivier Fiset, Daniela F. Quail, Jonathan D. Spicer, Logan A. Walsh

“…Our findings underscore the importance of analyzing NSCLC histological subtypes separately when investigating the spatial immune landscape, as microenvironmental characteristics and cellular interactions differed by subtype. …”
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Digital interactive experience- and game-based fall interventions for community-dwelling healthy older adults: a cross-disciplinary systematic review by Celina Ciemer, Celina Ciemer, Lisa Kröper, Thomas Jürgen Klotzbier, Sabiha Ghellal, Nadja Schott

“…Digital, interactive interventions, incorporating experience-, and game-related aspects, offer a promising solution, making this topic inherently cross-disciplinary.ObjectiveThis review aims to assess the current landscape of digital interactive experience and game-based fall interventions for community-dwelling, healthy older adults. …”
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Synthetic peptides as valuable and versatile tools for research: our 20 year journey in Chile by Constanza Cárdenas, Paula Santana, Claudio Álvarez, Luis Mercado, Sergio Marshall, Fernando Albericio, Fanny Guzmán

“…In this report, we provide an overview of the extensive application landscape of synthetic peptides, presenting examples developed in-house across different areas which include a summary of the methodologies and results obtained.…”
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Assessing Four Decades of Land Use and Land Cover Change: Policy Impacts and Environmental Dynamics in the Min River Basin, Fujian, China by Weixuan Huang, Anil Shrestha, Yifan Xie, Jianwu Yan, Jingxin Wang, Futao Guo, Yuee Cao, Guangyu Wang

“…First, we mapped and quantified changes (i.e., LULCC and landscape indices) in forests, croplands, urban areas, and water bodies from 1980 to 2020 using the China National Land Use/Cover Change (CNLUCC) and ArcGIS Pro 2.3. …”
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Sensor-controlled fertigation management for higher yield and quality in greenhouse hydroponic strawberries by George Kerrigan Hutchinson, Lan Xuan Nguyen, Zilfina Rubio Ames, Krishna Nemali, Rhuanito Soranz Ferrarezi

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Historical and projected forest cover changes in the Mount Kenya Ecosystem: Implications for sustainable forest management by Brian Rotich, Abdalrahman Ahmed, Benjamin Kinyili, Harison Kipkulei

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Comprehensive computational analysis of differentially expressed miRNAs and their influence on transcriptomic signatures in prostate cancer by Fahad M. Aldakheel, Hadeel Alnajran, Ayesha Mateen, Shatha A. Alduraywish, Mohammed S. Alqahtani, Rabbani Syed

“…These findings both reinforce our current understanding of prostate cancer’s molecular landscape and point to unexplored pathways that could lead to novel therapeutic strategies. …”
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Mitigation of environmental impacts in ornamental rock and limestone aggregate quarries in arid and semi-arid areas by M.A. Peñaranda Barba, V. Alarcón Martínez, I. Gómez Lucas, J. Navarro Pedreño

“…All of this has given rise to numerous active and abandoned mines, where no restoration process has been carried out, generating strong impacts on the environment.METHODS: In this study, 8 environmental impact assessments studies of ornamental rock and aggregate quarries in the Region of Murcia were analysed to identify the negative impacts on the abiotic and biotic environment, landscape, socio-economic and socio-cultural environment, and infrastructures and analysing preventive and control measures. …”
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Heat shock transcription factor 1 facilitates liver cancer progression by driving super‐enhancer‐mediated transcription of MYCN by Yizhe Liu, Qili Shi, Yue Su, Zhiao Chen, Xianghuo He

“…Additionally, we utilized CUT&Tag, H3K27 acetylation enrichment, and RNA sequencing (RNA‐seq) to investigate the super‐enhancer (SE) regulatory landscapes of HSF1 in liver cancer cell lines. Results HSF1 expression is elevated in HCC and is linked to poor prognosis in several datasets. …”
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The Mediating Role of Cognitive Reappraisal on Bedtime Procrastination and Sleep Quality in Higher Educational Context: A Three-Wave Longitudinal Study by Zhang Y, Rehman S, Addas A, Ahmad M, Khan A

“…Yuan Zhang,1 Shazia Rehman,2 Abdullah Addas,3,4 Mehmood Ahmad,5 Ayesha Khan6 1College of Art, Nanyang Vocational College of Agriculture, Nan Yang, Henan, 47300, People’s Republic of China; 2Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, People’s Republic of China; 3Department of Civil Engineering, College of Engineering, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia; 4Landscape Architecture Department, Faculty of Architecture and Planning, King Abdulaziz University, Jeddah, 21589, Saudi Arabia; 5Department of Pharmacology and Toxicology, Faculty of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan; 6Department of Applied Psychology, Faculty of Social Sciences, The Islamia University of Bahawalpur, Bahawalpur, 63100, PakistanCorrespondence: Shazia Rehman, Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, People’s Republic of China, Tel +86-13308429613, Email rehmanshazia.malik@gmail.comBackground: While bedtime procrastination is commonly associated with adverse outcomes such as poor sleep quality, the mechanisms mediating these effects remain underexplored. …”
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Anxiety disorders and the gut microbiota: a bibliometric and visual analysis by Linli Guo, Linli Guo, Qin Ding, Qin Ding, Qing Li, Danping Zheng, Danping Zheng, Linglin Guo, Linglin Guo, Xiaotao Cao, Xiaotao Cao, Qianqian Mou, Qianqian Mou

“…This study aims to assess the current global research landscape, highlight current topics of interest, and explore future research directions in the field of anxiety disorders and gut microbiota.MethodsWe extracted research review articles related to anxiety and gut microbiota from the Web of Science, covering the period from 2004 to 2023. …”
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Management of chimeric antigen receptor T-cell-related toxicity of a patient affected by cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome, follo... by G. Menardi, A. Castellino, C. Castellino, M. E. Bersia, E. Grande, G. Fraternali, M. Massaia, C. Fruttero

“…The study emphasizes the evolving landscape of chimeric antigen receptor T-cell therapy and the significance of addressing toxicities associated with this innovative treatment approach. …”
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Epidemics In The 21st Century: A Multifaceted Challenge by Shawana Sharif

“…Amidst the convoluted landscape of epidemics, medical professionals confront an amalgamation of challenges. …”
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Securing black lion tamarin populations: improving habitat-based inputs and risks for population viability analysis to inform management decisions by Francy Forero-Sánchez, Francy Forero-Sánchez, Gabriela Cabral Rezende, Gabriela Cabral Rezende, Cláudio Valladares-Pádua, Cláudio Valladares-Pádua, Fabio Stucchi Vannucchi, Fabio Stucchi Vannucchi, Leandro Jerusalinsky, Leandro Jerusalinsky, Luciana Pacca, Kathy Traylor-Holzer

“…Climate change and fire risk data were incorporated to project future carrying capacity, and habitat connectivity supported estimates of black lion tamarin dispersal across this fragmented landscape. The resulting population viability projections using Vortex simulation software identify core subpopulations with low extinction risk and high gene diversity, as well as smaller subpopulations with low long-term viability, highlighting the need for targeted conservation strategies across the fragmented metapopulation.…”
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Inhibition of histone deacetylase in Arabidopsis root calli promotes de novo shoot organogenesis by Qinwei Pan, Ruirui Huang, Qiong Xiao, Xuting Wu, Baoxia Jian, Yanan Xiang, Lijun Gan, Zongrang Liu, Yi Li, Tingting Gu, Huawei Liu, Huawei Liu

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