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3501
Glucose-Sensing Carbohydrate Response Element-Binding Protein in the Pathogenesis of Diabetic Retinopathy
Published 2025-01-01“…The retinal proteomic landscape revealed a decline in the KEGG pathways associated with phototransduction, amino acid metabolism, and cell adhesion. …”
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3502
Cuproptosis Cell Death Molecular Events and Pathways to Liver Disease
Published 2025-01-01“…Over the past few decades, the global landscape of chronic liver diseases, including hepatitis, metabolic dysfunction-associated steatotic liver disease (MASLD), liver fibrosis, and HCC, has undergone substantial changes. …”
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3503
Integrating Drone Truthing and Functional Classification of Remote Sensing Time Series for Supervised Vegetation Mapping
Published 2025-01-01“…This study proposes an approach to enhance the efficiency of supervised vegetation mapping in complex landscapes, integrating Multivariate Functional Principal Component Analysis (MFPCA) applied to the Sentinel-2 time series with drone-based ground truthing. …”
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3504
Improving Media Literacy Among Higher Education Students Through Vitagenic Information
Published 2025-01-01“…The primary focus is on how students can leverage their personal experiences and vitagenic learning to critically assess and interact with a wide array of media content in the current digital landscape. Background. As digital media and information become increasingly prevalent, students in higher education regularly encounter a significant volume of content that necessitates advanced critical evaluation skills. …”
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3505
UAV-Based Survey of the Earth Pyramids at the Kuklica Geosite (North Macedonia)
Published 2024-12-01“…The final goal was to monitor the changes and to minimize the degradation of the unique landscape, thus better protecting the geosite and its value.…”
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3506
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3507
Addressing the rising colorectal cancer burden in the older adult: examining modifiable risk and protective factors for comprehensive prevention strategies
Published 2025-02-01“…This comprehensive analysis aims to explore the complex epidemiological patterns of colorectal cancer, with a focus on the association between high BMI and disease burden in the older adult.MethodsThe study leveraged data from the Global Burden of Disease (GBD) 2021 study to examine the temporal trends, regional disparities, and the interplay of age, period, and cohort factors in shaping the global colorectal cancer landscape. Epidemiological techniques, including age-period-cohort modeling and joinpoint regression analysis, were employed to provide insights into the potential drivers of the evolving disease burden while controlling for relevant confounding factors.ResultsThe analysis revealed significant geographical disparities in the burden of colorectal cancer among the older adult population. …”
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3508
Exercise training and chronic kidney disease: characterization and bibliometrics of citation classics of clinical intervention trials
Published 2024-12-01“…This study analyzes citation classics on clinical intervention trials on exercise training and CKD to describe the research landscape and hotspots through bibliometric analysis.Methods To identify clinical trials of exercise training interventions for CKD with more than 100 citations from the Web of Science Core Collection database. …”
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3509
Case report: Personalized management of treatment resistance in advanced NSCLC patients with mutated epidermal growth factor receptor: special examples and literature review
Published 2025-02-01“…The treatment landscape of non-small cell lung cancer (NSCLC) has shifted significantly from empirical, histology-driven, and clinician-directed cytotoxic regimens to a stratified approach predicated on molecular profiling of tumor genetics and immune biomarkers, by the former can indicate targeted therapy that bull’s eye hits the arrow, while the latter can hint the benefit amplitude of immune checkpoint inhibitors (ICBs). …”
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3510
Care, conflict, and coexistence: Human–wildlife relations in community forests
Published 2025-01-01“…These multifaceted human–wildlife relationships, shaped by encounters in a shared landscape, inform communities' decisions and coping strategies for coexisting with their wild neighbours. …”
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3511
A bibliometric analysis of the effects of electronic waste on the environment
Published 2022-10-01“…This study provides an overview of the research landscape on the impact of e-waste on the environment using bibliometric analysis. …”
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3512
PROFILES OF FILIPINO TEACHERS AND THEIR ONLINE TEACHING COMPETENCIES DURING THE PANDEMIC
Published 2024-02-01“…In conclusion, this research provides insights into the current landscape of online teaching proficiency among Filipino educators, highlighting both strengths and areas for improvement. …”
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3513
Transitioning from wet lab to artificial intelligence: a systematic review of AI predictors in CRISPR
Published 2025-02-01“…Furthermore, it provides details of 80 available CRISPR-Cas9 system-related datasets that can be utilized to develop AI-driven applications. Within the landscape of AI predictors in CRISPR-Cas9 multi-step process, it provides insights of representation learning methods, machine and deep learning methods trends, and performance values of existing 50 predictive pipelines. …”
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3514
EVALUATION OF SMARTNESS OF THE TOURISM DESTINATION WEBSITES OF THE KLAIPEDA REGION
Published 2024-12-01“…In the contemporary era, the concept of smart cities, propelled by telecommunications-based information and communication technologies (ICT), is transforming the urban landscape. The concept of a smart city is not merely concerned with operational efficiency; it also seeks to enhance the overall value and quality of life for residents. …”
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3515
Investigation of Borrow Pit TEA28 BP3, Fenstanton, Cambridgeshire, UK
Published 2024-12-01“…The data also indicated a floodplain landscape occupied by a mosaic of ponds, marsh-fens, grassland, willow scrub and disturbed ground habitats. …”
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3516
Digestive cancers: mechanisms, therapeutics and management
Published 2025-01-01“…This knowledge is continuously translated into novel treatment concepts and targets, which are dynamically reshaping the therapeutic landscape of these tumors. In this review, we provide a concise overview of the etiology and molecular pathology of the six most common cancers of the digestive system, including esophageal, gastric, biliary tract, pancreatic, hepatocellular, and colorectal cancers. …”
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3517
From Night to Light: A Bibliometric Analysis of the Global Research Trajectory of Sleep Disorders in Parkinson’s Disease
Published 2025-01-01“…Emerging keywords include machine learning, sleep quality, biomarkers, covid-19, and mouse model.Conclusion: This bibliometric analysis sheds light on the global landscape of PD-related sleep disorder research over the past two decades, highlighting key countries, institutions, authors, and journals driving advancements in the field. …”
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3518
Numerical modelling of the hydrodynamics driven by tidal flooding of the land surface after dyke breaching
Published 2025-06-01“…A numerical model with an unstructured flexible mesh (Delft3D-FM) was applied to examine the impacts of tidal flooding from a river channel, through the dyke breach and across the previously agricultural landscape that was historically a salt marsh. The model was used to simulate the hydrodynamics inside and around the breach before and after seawater flooding during spring tides, to evaluate the initial impacts of this nature-based method of managed dyke realignment. …”
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3519
Economic and ecological perspectives of farmers on rice insect pest management
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3520
Diversification outbreaks and dynamics of Asian leaf-litter frogs, genus Leptobrachella (Anura, Megophryidae), with the description of a new species from Guizhou Province, China
Published 2025-02-01“…These two geologic events greatly altered topography and drainage patterns that, in turn, affected the regional climate, the landscape and the evolution of biodiversity. Despite this, little is known about how orogeny and climate affect the evolution of biodiversity, especially the dynamics of diversification, including origins, peaks and endings. …”
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