Prediction of potential drug targets and key inhibitors (ZINC67974679, ZINC67982856, and ZINC05668040) against Rickettsia felis using integrated computational approaches by Sudais Rahman, Hsien Liu, Mohibuallah Shah, Mashal M. Almutairi, Iram Liaqat, Tetsuya Tanaka, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Abdulaziz Alouffi, Abid Ali

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Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis by Mengling Wang, Feng Zeng, Fengling Ning, Yinhang Wang, Shilin Zhou, Jiaqi He, Cong Li, Cong Wang, Xiaolin Sun, Dongliang Zhang, Jisheng Xiao, Ping Hu, Svetlana Reilly, Hong Xin, Xudong Xu, Xuemei Zhang

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Influence of Arbuscular Mycorrhizal Fungi on Nitrogen Dynamics During <i>Cinnamomum camphora</i> Litter Decomposition by Yuehong Gao, Xiaoyu Long, Yiqi Liao, Yonghui Lin, Zaihua He, Qin Kong, Xiangshi Kong, Xingbing He

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<i>KRAS</i>, <i>NRAS</i>, and <i>BRAF</i> Hot-Spot Mutations in Relation to Sidedness of Primary Colorectal Cancer: A Retrospective Cohort Study by Omer Abdelgadir, Yong-Fang Kuo, Anthony O. Okorodudu, M. Firoze Khan, Yu-Wei Cheng, Jianli Dong

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Six-Phase Fully Coreless Axial-Flux Permanent-Magnet Generator: Design, Fabrication, and Performance Analysis by Turki M. Alsuwian, Asiful Habib, Muhammad Ammirrul Atiqi Mohd Zainuri, Ahmad Asrul Ibrahim, Nasrudin Abd Rahim, Adam R. H. Alhawari, Abdulkarem H. M. Almawgani, Saleh Almasabi, A. T. Hindi, Mohamed Fauzi Packeer Mohamed

“…To realize this aim, a six-phase multi-stage AFPM generator was designed and simulated using ANSYS Maxwell. Subsequently, a laboratory-scale prototype was fabricated accordingly. …”
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Corticomuscular Coupling Alterations During Elbow Isometric Contraction Correlated With Clinical Scores: An fNIRS-sEMG Study in Stroke Survivors by Xiaohan Wang, Weidong Li, Rong Song, Di Ao, Huijing Hu, Le Li

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Aldehyde Dehydrogenase 2 rs671 Polymorphism is Associated with Susceptibility of Coronary Atherosclerosis in Patients with Hypertension by Hou H, Huang S, Huang W, Huang L, Zhang Z, Liang L

“…Haisong Hou,1 Sina Huang,2 Wenyi Huang,3 Lingmei Huang,1 Zhouhua Zhang,4 Liu Liang5 1Department of Blood Transfusion, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 2Department of Cardiovascular Surgery, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 3Center for Surgical Operation, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 4Center for Cardiovascular Diseases, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 5Department of Laboratory Medicine, Meizhou People’s Hospital, Meizhou, People’s Republic of ChinaCorrespondence: Haisong Hou, Department of Blood Transfusion, Meizhou People’s Hospital, Meizhou, People’s Republic of China, Email houhaisonggd6@163.comObjective: Predisposing factors for coronary atherosclerosis in hypertensive individuals are unclear. …”
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A predictive risk‐scoring model for survival prognosis of multiple myeloma based on gain/amplification of 1q21: Experience in a tertiary hospital in South‐Western China by Yanqiu Xiong, Shanshan Liang, Wenjiao Tang, Li Zhang, Yuhuan Zheng, Ling Pan, Ting Niu

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Weak coupling of observed surface PM2.5 in Delhi-NCR with rice crop residue burning in Punjab and Haryana by Poonam Mangaraj, Yutaka Matsumi, Tomoki Nakayama, Akash Biswal, Kazuyo Yamaji, Hikaru Araki, Natsuko Yasutomi, Masayuki Takigawa, Prabir K. Patra, Sachiko Hayashida, Akanksha Sharma, A. P. Dimri, Surendra K. Dhaka, Manpreet S. Bhatti, Mizuo Kajino, Sahil Mor, Ravindra Khaiwal, Sanjeev Bhardwaj, Vimal J. Vazhathara, Ravi K. Kunchala, Tuhin K. Mandal, Prakhar Misra, Tanbir Singh, Kamal Vatta, Suman Mor

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Clinical validation and optimization of machine learning models for early prediction of sepsis by Xi Liu, Meiyi Li, Xu Liu, Yuting Luo, Dong Yang, Hui Ouyang, Jiaoling He, Jinyu Xia, Fei Xiao, Fei Xiao, Fei Xiao

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Clinical and Immunological Characteristics of Elderly Onset Rheumatoid Arthritis by LI Zhengfang, WU Chanyuan, MA Mengsi, LI Tingting, WU Xue, MENG Xinyan, ZHANG Sha, WU Lijun

“…The demographic data, clinical characteristics, extra-articular manifestations and laboratory examination results of the patients were collected. …”
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DNA-loaded targeted nanoparticles as a safe platform to produce exogenous proteins in tumor B cells by Maria Cristina Grimaldi, Sara Bozzer, Dick J. Sjöström, Dick J. Sjöström, Linnea I. Andersson, Tom Eirik Mollnes, Tom Eirik Mollnes, Per H. Nilsson, Per H. Nilsson, Luca De Maso, Federico Riccardi, Michele Dal Bo, Daniele Sblattero, Paolo Macor

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A Review of Marine Bacterial Intracellular and Extracellular Bioactive Compounds as Novel Antibacterial and Anti-Inflammation Agents by Harningsih Karim, Arief Azis, Ananda Ramadani, Anita Anita, Ahyar Ahmad, Hasnah Natsir, Paulina Taba, Suriati Eka Putri, Sarlan Sarlan, Siti Halimah Larekeng, Rizal Irfandi

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Epidemiology, clinical spectrum, and outcomes of severe malaria in Eastern Uganda: a prospective study by Cate Namayanja, George Paasi, Jimmy Patrick Alunyo, Denis Amorut, Charles Benard Okalebo, William Okiror, Paul Ongodia, Grace Abongo, Rita Muhindo, Yovani A. M. Lubaale, Peter Olupot-Olupot

“…Data were collected using a customized proforma on social demographic characteristics, clinical presentation, treatment, and outcomes. Laboratory analyses included complete blood counts, lactate, glucose, blood gases, electrolytes, metabolites, and coagulation markers. …”
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Gut Microbiome and Metabolite Characteristics Associated With Different Clinical Stages in Non-Small Cell Lung Cancer Patients by Liu F, Lu X, Tang M, Chen Y, Zheng X

“…Fan Liu,1 Xingbing Lu,2 Mengli Tang,2 Yuzuo Chen,2 Xi Zheng3,4 1Health Management Center, General Practice Medical Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 3Lung Cancer Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 4Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, People’s Republic of ChinaCorrespondence: Xi Zheng, Lung Cancer Center, Department of Thoracic Surgery, West China Hospital, Sichuan University, Guoxue Lane 37, Chengdu, Sichuan Province, People’s Republic of China, Tel +86-28-86298113, Email zhengxi@scu.edu.cnObjective: Our research has pinpointed the gut microbiome’s role in the progression of various pathological types of non-small cell lung cancer (NSCLC). …”
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Neuroprotective Effects of Eugenol Acetate Against Ischemic Stroke by Chen L, Zhang R, Xiao J, Liang Y, Lan Z, Fan Y, Yu X, Xia S, Yang H, Bao X, Meng H, Xu Y, Yu L, Zhu X

“…Liqiu Chen,1,2,&ast; Ran Zhang,1,2,&ast; Jing Xiao,1,2,&ast; Ying Liang,1,2 Zhen Lan,3 Yingao Fan,2 Xi Yu,2 Shengnan Xia,2– 5 Haiyan Yang,2– 5 Xinyu Bao,2– 5 Hailan Meng,1– 6 Yun Xu,1– 6 Linjie Yu,1– 6 Xiaolei Zhu1– 6 1Department of Neurology, Nanjing Drum Tower Hospital, Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, People’s Republic of China; 2Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People’s Republic of China; 3Department of Neurology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, 210008, People’s Republic of China; 4State Key Laboratory of Pharmaceutical Biotechnology and Institute of Translational Medicine for Brain Critical Diseases, Nanjing University, Nanjing, 210008, People’s Republic of China; 5Jiangsu Provincial Key Discipline of Neurology, Nanjing, 210008, People’s Republic of China; 6Nanjing Neurology Medical Center, Nanjing, 210008, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Linjie Yu; Xiaolei Zhu, Department of Neurology, Nanjing Drum Tower Hospital, Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, People’s Republic of China, Email yulinjie126@126.com; zhuquelee@126.comObjective: To explore the neuroprotective effect of Eugenol Acetate (EA) on post-stroke neuroinflammation and investigate the underlying mechanisms.Methods: For in vitro experiments, primary microglia were pre-incubated with EA for 2 hours, followed by lipopolysaccharide (LPS) stimulation for 24 hours or Oxygen-Glucose Deprivation (OGD) treatment for 4 hours. …”
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Standardised protocol for a prospective cross-sectional multicentre clinical utility evaluation of two dual point-of-care tests in non-clinical settings for the screening of HIV an... by James Kiarie, Karel Blondeel, Igor Toskin, Jordi Casabona, Soe Soe Thwin, Massimo Mirandola, Rosanna Peeling, Ronald Ballard, Laura Fernàndez-López, Inga Upmace, Juliana Reyes-Urueña, Mara Vaselova, Mitja Ćosić, Simon Maljevac, William Mejías, Ander Pazos, Andrii Chernyshev

“…Introduction Point-of-care dual tests (POCTs) for simultaneously detecting antibodies to HIV and syphilis (dual HIV-syphilis POCTs) have been developed recently and show encouraging performance compared with the reference tests in laboratory-based studies. As community-based voluntary, counselling and testing (CBVCT) services are effective providers of HIV and syphilis testing and counselling with high acceptability among men who have sex with men (MSM), the evaluation of the utility of these dual tests in CBVCT services is a high priority. …”
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FoodMicroDB: A microbiome database for composition and time‐series research in food by Yahui Li, Hujie Lyu, Haifei Yang, Zhicheng Ju, Chuang Ma, Huiyu Hou, Yao Wang, Yuanping Zhou, Yunyun Gao, Junbo Yang, Shanshan Xu, Defeng Bai, Hao Luo, Salsabeel Yousuf, Tianyuan Zhang, Jiani Xun, Meiyin Zeng, Heyuan Qi, Tong Chen, Yong‐Xin Liu

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Real-time data processing for serial crystallography experiments by Thomas White, Tim Schoof, Sergey Yakubov, Aleksandra Tolstikova, Philipp Middendorf, Mikhail Karnevskiy, Valerio Mariani, Alessandra Henkel, Bjarne Klopprogge, Juergen Hannappel, Dominik Oberthuer, Ivan De Gennaro Aquino, Dmitry Egorov, Anna Munke, Janina Sprenger, Guillaume Pompidor, Helena Taberman, Andrey Gruzinov, Jan Meyer, Johanna Hakanpää, Martin Gasthuber

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DKK2 Impairs Tumor Immunity Infiltration and Correlates with Poor Prognosis in Pancreatic Ductal Adenocarcinoma by Jianyu Yang, Yongsheng Jiang, Ruizhe He, Wei Liu, Minwei Yang, Lingye Tao, Xueliang Fu, Yang Shen, Jiao Li, Dejun Liu, Yanmiao Huo, Junfeng Zhang, Rong Hua, Zhigang Zhang, Yongwei Sun

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