Amine Analysis Using AlexaFluor 488 Succinimidyl Ester and Capillary Electrophoresis with Laser-Induced Fluorescence by Christian G. Kendall, Amanda M. Stockton, Stephen Leicht, Heather McCaig, Shirley Chung, Valerie Scott, Fang Zhong, Ying Lin

“…Limits of detection using the optimized labeling conditions and these separation conditions were 5–17 nM. …”
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Machine Learning Algorithms Analysis of Synthetic Minority Oversampling Technique (SMOTE): Application to Credit Default Prediction by Emmanuel de-Graft Johnson Owusu-Ansah, Richard Doamekpor, Richard Kodzo Avuglah, Yaa Kyere Adwubi

“…This problem often arises in classification jobs if the distribution of classes or labels in a dataset is not uniform. To overcome this issue, just resample by adding or removing entries from the minority or majority classes. …”
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Navigating Recent Changes in Dosing Information: Dynamics of FDA‐Approved Monoclonal Antibodies in Post‐Marketing Realities by Nai Lee, Su‐jin Rhee, Seong Min Koo, So Won Kim, Gyo Eun Lee, Yoon A Yie, Yun Kim

“…This review evaluates post‐marketing label changes in dosing information for FDA‐approved mAbs from January 2015 to September 2024, with a focus on both initial and extended indications. …”
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Model-Oriented Training of Coordinators of the Decentralized Control System of Technological Facilities With Resource Interaction by Volodymyr M. Dubovoi, Maria S. Yukhimchuk, Viacheslav V. Kovtun, Krzysztof R. Grochla

“…However, the coordinators’ training process is complicated by the lack of labelled datasets for technological facilities. In decentralized control systems, the problem is complicated by the need to train all coordinators, with the outcome depending on the coordinator’s position within the structure of the distributed control system. …”
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Randomised feasibility study of an intestinal adsorbent in acute diarrhoea in The Gambia by Elena Markaryan, Matthew Dodd, Stephen Allen, Carol Howell, Angela Allen, Paul Rahden, Abdoulie Fatty, Momodou Lamin Jobarteh, Abdoulwahab Sallah, Ebrahim Jaiteh, Doreen Umoh, Fanta Bass, Radovan Hnatič

“…An intestinal adsorbent may reduce diarrhoea duration and severity.Methods Randomised controlled feasibility trial with two phases: phase 1 (0–4 hours and double-blind) and phase 2 (up to 5 days and open-label). 50 children aged 6–59 months with acute diarrhoea presenting with no or some dehydration to the emergency paediatric unit and outpatient clinic at Edward Francis Small Teaching Hospital, Banjul, The Gambia were randomised to either standard treatment (oral rehydration fluid and zinc) or standard treatment with polymethylsiloxane polyhydrate for up to 5 days.Results Recruitment was completed in 7 months. …”
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Forest Fire Clustering: A Novel Tool for Identifying Star Members of Clusters by Xingyin Wei, Jing Chen, Su Zhang, Feilong He, Yunbo Zhao, Xuran He, Yongjie Fang, Xinhao Chen, Hao Yang

“…FFC combines iterative label propagation with parallel Monte Carlo simulation to achieve internal validation of clustering results. …”
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Predicting branch retinal vein occlusion development using multimodal deep learning and pre-onset fundus hemisection images by Eun Young Choi, Dongyoung Kim, Jinyeong Kim, Eunjin Kim, Hyunseo Lee, Jinyoung Yeo, Tae Keun Yoo, Min Kim

“…A U-net model segmented retinal optic discs and blood vessels (BVs), dividing them into upper and lower halves labeled for BRVO occurrence. Both unimodal models (using either fundus or BV images) and a BV-enhanced multimodal model were constructed to predict future BRVO. …”
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Early Detection of Multiwavelength Blazar Variability by Hermann Stolte, Jonas Sinapius, Iftach Sadeh, Elisa Pueschel, Matthias Weidlich, David Berge

“…Based on unsupervised anomaly detection and clustering methods, we differentiate source variability from noisy background activity, without the need for a labeled training data set of flaring states. The framework incorporates measurement uncertainties and is robust given data quality challenges, such as varying cadences and observational gaps. …”
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Proteomic Identification of Heat Shock-Induced Danger Signals in a Melanoma Cell Lysate Used in Dendritic Cell-Based Cancer Immunotherapy by Fermín E. González, Alexey Chernobrovkin, Cristián Pereda, Tamara García-Salum, Andrés Tittarelli, Mercedes N. López, Flavio Salazar-Onfray, Roman A. Zubarev

“…Here, we characterized the proteomic profile of TRIMEL in response to HS treatment. A quantitative label-free proteome analysis of over 2800 proteins was performed, with 91 proteins that were found to be regulated by HS treatment: 18 proteins were overexpressed and 73 underexpressed. …”
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Traditional Chinese Medicine Prescription Generation Model Based on Search Enhancement by ZHAO Zijuan, REN Xueting, SONG Kai, QIANG Yan, ZHAO Juanjuan, ZHANG Junlong

“…In addition, the proposed model can recommend herbs that do not appear on the prescription label but are useful for relieving symptoms, which shows that the model can learn some interactions between herbs and symptoms. …”
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Stem Cells from Human Exfoliated Deciduous Teeth Attenuate Trigeminal Neuralgia in Rats by Xiaofeng Bai, Xuedi Zhang, Chun Wang, Yao Liu, Xuemei Liu, Yu Fan, Xia Zhang

“…The data showed that systemic or local injection of SHED attenuated the sensitivity of rats to mechanical stimuli after nerve injury, and this effect lasted throughout the observation period of 8 weeks. PKH26-labeled SHED were distributed to the ipsilateral trigeminal ganglions 24 and 72 hours after local injection. …”
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Photoplethysmography based psychological stress detection with pulse rate variability feature differences and elastic net by Fenghua Li, Peida Xu, Shichun Zheng, Wenfeng Chen, Yang Yan, Suo Lu, Zhengkui Liu

“…The correct prediction took 86%–91% of the testing samples with error standard deviation of 0.68–0.81 in the label space of 14. By simplifying the process of prediction with a perspective of stress difference and handling the collinearity among pulse rate variability features with elastic net, we successfully built a stress prediction model with only pulse rate variability input source, fine granularity output and portable friendly sensor.…”
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Engineering p‐Orbital States via Molecular Modules in All‐Organic Electrocatalysts toward Direct Water Oxidation by Li‐Hong Yu, Xue‐Feng Zhang, Zi‐Ming Ye, Hong‐Gang Du, Li‐Dong Wang, Ping‐Ping Xu, Yuhai Dou, Li‐Ming Cao, Chun‐Ting He

“…Operando differential electrochemical mass spectrometry (DEMS) with isotope labeling identifies the adsorbate evolution mechanism (AEM). …”
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Extracellular vesicles in seminal plasma of Sahiwal cattle bulls carry a differential abundance of sperm fertility-associated proteins for augmenting the functional quality of low-... by Ankit Pal, Seema Karanwal, Mir Ahmad Habib, Fanny Josan, Vikrant Gaur, Aditya Patel, Muskaan Garg, Mukesh Bhakat, Tirtha K. Datta, Rakesh Kumar

“…Fertility-associated proteins such as SP10, ADAM7, and SPAM 1 were highly expressed in SPEVs of high-fertility (HF) bulls. PKH26 dye-labeled SPEVs demonstrated significant uptake by spermatozoa at pH 6.8 with ≥ 4 h of co-incubation. …”
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Pilot clinical trial of neoadjuvant toll-like receptor 7 agonist (Imiquimod) immunotherapy in early-stage oral squamous cell carcinoma by Angela J. Yoon, Richard D. Carvajal, Evan M. Graboyes, John M. Kaczmar, William G. Albergotti, Alexandra E. Kejner, Scott H. Troob, Elizabeth Philipone, Jean-Sebastien Anoma, Kent E. Armeson, Elizabeth G. Hill, Mary S. Richardson, Tina R. Woods, Bhishamjit S. Chera, Farzad Nourollah-Zadeh, Byung J. Lee, Subramanya Pandruvada, Antonis Kourtidis, Christina Kingsley, Elizabeth C. O’Quinn, Stephanie Mills, Victoria C. Jordan, Mike Spencer, Danielle Fails, Trevor D. McKee, Mark Zaidi, Alan Brisendine, Shane Horn, Shikhar Mehrotra, Besim Ogretmen, Jason G. Newman

“…We report a single-arm, open-label, pilot clinical trial assessing the efficacy and safety of topical toll-like receptor-7 (TLR-7) agonist, imiquimod, utilized in a neoadjuvant setting in early-stage oral squamous cell carcinoma (OSCC).MethodsThe primary endpoint is reduction in tumor cell counts assessed by quantitative multiplex immunofluorescence and the immune-related pathologic response. …”
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TTSNet: Transformer–Temporal Convolutional Network–Self-Attention with Feature Fusion for Prediction of Remaining Useful Life of Aircraft Engines by Zhaofei Li, Shilin Luo, Haiqing Liu, Chaobin Tang, Jianguo Miao

“…Finally, a fully connected layer is used to establish the mapping relationship between the feature matrix and the RUL label, obtaining the RUL prediction value. The model was validated on the C-MAPSS aircraft engine dataset. …”
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An Investigation of Presumptive Synergism of Oil Palm Bunch Ash and Sawdust Amendments in Remediation of crude oil Spiked Soil by Ejikeme Albert, Di Anyanwu

“…Two kilogram (2 kg) of sandy soil was placed in each of five plastic vessels labeled TA, TB, TC, TD and TE. TA was left in its natural state while the others were each polluted with 6.7% v/w of crude oil. …”
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Edoxaban Monotherapy in Nonvalvular Atrial Fibrillation Patients with Coronary Artery Disease by Daisuke Fukamachi, Yasuo Okumura, Naoya Matsumoto, Eizo Tachibana, Koji Oiwa, Makoto Ichikawa, Hironori Haruta, Kazumiki Nomoto, Ken Arima, Atsushi Hirayama

“…A multicenter, prospective, randomized, open-label, and parallel group study was established to investigate the safety of an edoxaban monotherapy in patients with NVAF and stable CAD including over 6 months postimplantation of a third-generation DES and 1 year postimplantation of other stents (PRAEDO AF study). …”
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Addressing widespread misidentifications of traditional medicinal mushrooms in Sanghuangporus (Basidiomycota) through ITS barcoding and designation of reference sequences by Shan Shen, Shi-Liang Liu, Ji-Hang Jiang, Li-Wei Zhou

“…However, inappropriately labeled ITS sequences of “Sanghuang” in GenBank restrict accurate species identification and, to some extent, the utilization of these species as medicinal resources. …”
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‘Photodynamic therapy light’: An enhanced treatment protocol for actinic keratoses with minimal pain and optimal clinical outcome by combining laser-assisted low irradiance PDT wit... by Martin T. Braun, Kelly Del Tredici, Anna Wölling, Luitgard Wiest

“…Therefore, we developed a novel off-label PDT protocol: ‘PDT light’. Methods: Laser-assisted low irradiance PDT (li-PDT) was performed beginning in 2014. …”
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